Find Arg-3-Hyp-7-Phe-Bradykinin manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Npc-567, Npc 567, 109333-26-8, (d-arg0,hyp3,d-phe7)-bradykinin, Dv64b0pleh, Chembl446325
Molecular Formula
C60H87N19O13
Molecular Weight
1282.5  g/mol
InChI Key
RBIXVHPHNGXTCI-QJTYZATASA-N
FDA UNII
DV64B0PLEH

Arg-3-Hyp-7-Phe-Bradykinin
1 2D Structure

Arg-3-Hyp-7-Phe-Bradykinin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S,4R)-1-[(2S)-1-[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]-4-hydroxypyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
2.1.2 InChI
InChI=1S/C60H87N19O13/c61-39(20-10-24-68-58(62)63)49(83)73-40(21-11-25-69-59(64)65)55(89)78-27-13-23-46(78)56(90)79-33-38(81)31-47(79)54(88)71-32-48(82)72-42(28-35-14-4-1-5-15-35)50(84)77-45(34-80)53(87)76-44(30-37-18-8-3-9-19-37)52(86)75-43(29-36-16-6-2-7-17-36)51(85)74-41(57(91)92)22-12-26-70-60(66)67/h1-9,14-19,38-47,80-81H,10-13,20-34,61H2,(H,71,88)(H,72,82)(H,73,83)(H,74,85)(H,75,86)(H,76,87)(H,77,84)(H,91,92)(H4,62,63,68)(H4,64,65,69)(H4,66,67,70)/t38-,39-,40+,41+,42+,43+,44-,45+,46+,47+/m1/s1
2.1.3 InChI Key
RBIXVHPHNGXTCI-QJTYZATASA-N
2.1.4 Canonical SMILES
C1CC(N(C1)C(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)N)C(=O)N2CC(CC2C(=O)NCC(=O)NC(CC3=CC=CC=C3)C(=O)NC(CO)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CC5=CC=CC=C5)C(=O)NC(CCCN=C(N)N)C(=O)O)O
2.1.5 Isomeric SMILES
C1C[C@H](N(C1)C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](CCCN=C(N)N)N)C(=O)N2C[C@@H](C[C@H]2C(=O)NCC(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CO)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)N[C@@H](CC5=CC=CC=C5)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)O
2.2 Other Identifiers
2.2.1 UNII
DV64B0PLEH
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Bradykinin, Arg(0)-hyp(3)-phe(7)-

2. Bradykinin, Arg-hyp(3)-phe(7)-

3. Bradykinin, Arginyl-hydroxyprolyl(3)-phenylalanine(7)-

4. Npc 567

5. Npc-567

2.3.2 Depositor-Supplied Synonyms

1. Npc-567

2. Npc 567

3. 109333-26-8

4. (d-arg0,hyp3,d-phe7)-bradykinin

5. Dv64b0pleh

6. Chembl446325

7. Chebi:73294

8. Arg(0)-hyp(3)-phe(7)-bradykinin

9. [d-arg(0),hyp(3),d-phe(7)]bradykinin

10. D-arg-arg-pro-hyp-gly-phe-ser-d-phe-phe-arg

11. D-arginyl-l-arginyl-l-prolyl-(4r)-4-hydroxy-l-prolylglycyl-l-phenylalanyl-l-seryl-d-phenylalanyl-l-phenylalanyl-l-arginine

12. Bradykinin, Arg-hyp(3)-phe(7)-

13. Unii-dv64b0pleh

14. Bradykinin, Arg(0)-hyp(3)-phe(7)-

15. Bradykinin, Arginyl-hydroxyprolyl(3)-phenylalanine(7)-

16. Gtpl676

17. D-arg-(hyp3,d-phe7)bradykinin

18. [d-arg0,hyp3,d-phe7]bradykinin

19. Bdbm50435301

20. Bim 31006

21. Bim-31006

22. Bradykinin, N2-d-arginyl-3-(trans-4-hydroxy-l-proline)-7-d-phenylalanine-

23. Q27088026

24. Bradykinin, N2-d-arginyl-3-((4r)-4-hydroxy-l-proline)-7-d-phenylalanine-

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 1282.5 g/mol
Molecular Formula C60H87N19O13
XLogP3-5.9
Hydrogen Bond Donor Count17
Hydrogen Bond Acceptor Count17
Rotatable Bond Count36
Exact Mass1281.67307391 g/mol
Monoisotopic Mass1281.67307391 g/mol
Topological Polar Surface Area541 Ų
Heavy Atom Count92
Formal Charge0
Complexity2550
Isotope Atom Count0
Defined Atom Stereocenter Count10
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Analgesics

Compounds capable of relieving pain without the loss of CONSCIOUSNESS. (See all compounds classified as Analgesics.)


ABOUT THIS PAGE

Arg-3-Hyp-7-Phe-Bradykinin Manufacturers

A Arg-3-Hyp-7-Phe-Bradykinin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Arg-3-Hyp-7-Phe-Bradykinin, including repackagers and relabelers. The FDA regulates Arg-3-Hyp-7-Phe-Bradykinin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Arg-3-Hyp-7-Phe-Bradykinin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Arg-3-Hyp-7-Phe-Bradykinin Suppliers

A Arg-3-Hyp-7-Phe-Bradykinin supplier is an individual or a company that provides Arg-3-Hyp-7-Phe-Bradykinin active pharmaceutical ingredient (API) or Arg-3-Hyp-7-Phe-Bradykinin finished formulations upon request. The Arg-3-Hyp-7-Phe-Bradykinin suppliers may include Arg-3-Hyp-7-Phe-Bradykinin API manufacturers, exporters, distributors and traders.

click here to find a list of Arg-3-Hyp-7-Phe-Bradykinin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Arg-3-Hyp-7-Phe-Bradykinin USDMF

A Arg-3-Hyp-7-Phe-Bradykinin DMF (Drug Master File) is a document detailing the whole manufacturing process of Arg-3-Hyp-7-Phe-Bradykinin active pharmaceutical ingredient (API) in detail. Different forms of Arg-3-Hyp-7-Phe-Bradykinin DMFs exist exist since differing nations have different regulations, such as Arg-3-Hyp-7-Phe-Bradykinin USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Arg-3-Hyp-7-Phe-Bradykinin DMF submitted to regulatory agencies in the US is known as a USDMF. Arg-3-Hyp-7-Phe-Bradykinin USDMF includes data on Arg-3-Hyp-7-Phe-Bradykinin's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Arg-3-Hyp-7-Phe-Bradykinin USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Arg-3-Hyp-7-Phe-Bradykinin suppliers with USDMF on PharmaCompass.

Arg-3-Hyp-7-Phe-Bradykinin GMP

Arg-3-Hyp-7-Phe-Bradykinin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Arg-3-Hyp-7-Phe-Bradykinin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Arg-3-Hyp-7-Phe-Bradykinin GMP manufacturer or Arg-3-Hyp-7-Phe-Bradykinin GMP API supplier for your needs.

Arg-3-Hyp-7-Phe-Bradykinin CoA

A Arg-3-Hyp-7-Phe-Bradykinin CoA (Certificate of Analysis) is a formal document that attests to Arg-3-Hyp-7-Phe-Bradykinin's compliance with Arg-3-Hyp-7-Phe-Bradykinin specifications and serves as a tool for batch-level quality control.

Arg-3-Hyp-7-Phe-Bradykinin CoA mostly includes findings from lab analyses of a specific batch. For each Arg-3-Hyp-7-Phe-Bradykinin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Arg-3-Hyp-7-Phe-Bradykinin may be tested according to a variety of international standards, such as European Pharmacopoeia (Arg-3-Hyp-7-Phe-Bradykinin EP), Arg-3-Hyp-7-Phe-Bradykinin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Arg-3-Hyp-7-Phe-Bradykinin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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