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Chemistry

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Also known as: L-arginine hydrochloride, 1119-34-2, L-arginine monohydrochloride, L-arginine hcl, H-arg-oh.hcl, Arginine hcl
Molecular Formula
C6H15ClN4O2
Molecular Weight
210.66  g/mol
InChI Key
KWTQSFXGGICVPE-WCCKRBBISA-N
FDA UNII
F7LTH1E20Y

L-Arginine Hydrochloride API
An essential amino acid that is physiologically active in the L-form.
1 2D Structure

L-Arginine Hydrochloride API

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid;hydrochloride
2.1.2 InChI
InChI=1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1
2.1.3 InChI Key
KWTQSFXGGICVPE-WCCKRBBISA-N
2.1.4 Canonical SMILES
C(CC(C(=O)O)N)CN=C(N)N.Cl
2.1.5 Isomeric SMILES
C(C[C@@H](C(=O)O)N)CN=C(N)N.Cl
2.2 Other Identifiers
2.2.1 UNII
F7LTH1E20Y
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Arginine

2. Arginine, L Isomer

3. Arginine, L-isomer

4. Dl Arginine Acetate, Monohydrate

5. Dl-arginine Acetate, Monohydrate

6. Hydrochloride, Arginine

7. L Arginine

8. L-arginine

9. L-isomer Arginine

10. Monohydrate Dl-arginine Acetate

2.3.2 Depositor-Supplied Synonyms

1. L-arginine Hydrochloride

2. 1119-34-2

3. L-arginine Monohydrochloride

4. L-arginine Hcl

5. H-arg-oh.hcl

6. Arginine Hcl

7. 15595-35-4

8. L-arginine, Monohydrochloride

9. Levargin

10. Arginine Monohydrochloride

11. Argamine

12. Argivene

13. Detoxargin

14. L-(+)-arginine Monohydrochloride

15. Minophagen A

16. (s)-2-amino-5-guanidinopentanoic Acid Hydrochloride

17. R-gene 10

18. R-gene

19. L-arginine (hydrochloride)

20. L-(+)-arginine Hydrochloride

21. (s)-(+)-arginine Hydrochloride

22. Arginine Monochloride

23. F7lth1e20y

24. L-arginine, Hydrochloride (1:1)

25. Mfcd00064550

26. Nsc-7914

27. Nsc-203450

28. L(+)-arginine Hydrochloride

29. (+)-l-arginine Hydrochloride

30. (2s)-2-amino-5-carbamimidamidopentanoic Acid Hydrochloride

31. L-arginine, Hydrochloride

32. Tivortin

33. R-gene (tn)

34. Arginine, Hydrochloride, L-

35. L-arginine Hydrochloride (van)

36. Arginine Hydrochloride [usan:jan]

37. Nsc 7914

38. Einecs 214-275-1

39. Unii-f7lth1e20y

40. Nsc 203450

41. (2s)-2-amino-5-carbamimidamidopentanoic Acid;hydrochloride

42. (2s)-2-amino-5-(diaminomethylideneamino)pentanoic Acid;hydrochloride

43. Ai3-18300

44. H-arg-oh?cl

45. L-argininexhydrochloride

46. L-arginine Xhydrochloride

47. L- Arginine Hydrochloride

48. L-arginine Monochlorhydrate

49. Ec 214-275-1

50. L-arginine Hcl (l-arg)

51. Argininine Monohydrocholoride

52. Arginine Hcl [inci]

53. Schembl44977

54. Arginine Hydrochloride (usp)

55. Chembl1200381

56. Chebi:31235

57. Hy-n0455a

58. L-arginine Hydrochloride Solution

59. Dtxsid20883650

60. L-arginine Hydrochloride (jp17)

61. Arginine Hydrochloride [mi]

62. L-arginine, Monohydrochloride, L-

63. Arginine, L-, Hydrochloride

64. Arginine Hydrochloride [usan]

65. Ccg-43265

66. S3174

67. Arginine Hydrochloride [vandf]

68. (s)-(+)-2-amino-5-[(aminoiminomethyl)amino]pentanoic Acid Monohydrochloride

69. Akos015906195

70. Akos015924214

71. Arginine Hydrochloride [mart.]

72. L-arginine Hydrochloride [jan]

73. Am81503

74. Arginine Hydrochloride [usp-rs]

75. Arginine Hydrochloride [who-dd]

76. Cs-2046

77. Ds-2054

78. Ac-23975

79. L-arginine Monohydrochloride [fcc]

80. Arginine Hydrochloride [orange Book]

81. Db-029943

82. A0528

83. A7080

84. Arginine Hydrochloride [ep Monograph]

85. Cs-0368604

86. Arginine Hydrochloride [usp Monograph]

87. A-8580

88. D01126

89. D70773

90. 119a342

91. A802447

92. Arginine Hydrochloride (l-arginine Hydrochloride)

93. L-arginine Monohydrochloride, Vetec(tm), 98.5%

94. J-521633

95. Sr-01000075479-3

96. Q27277776

97. L-arginine Hydrochloride, Saj Special Grade, >=99.0%

98. L-arginine Monohydrochloride, Bioultra, >=99.5% (at)

99. L-arginine Monohydrochloride, Vetec(tm) Reagent Grade, >=98%

100. L-arginine Monohydrochloride, Reagent Grade, >=98% (hplc), Powder

101. Arginine Hydrochloride, British Pharmacopoeia (bp) Reference Standard

102. Arginine Hydrochloride, European Pharmacopoeia (ep) Reference Standard

103. L-arginine Monohydrochloride, Certified Reference Material, Tracecert(r)

104. Arginine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

105. L-arginine Hydrochloride Solution, 100 Mm Amino Acid In 0.1 M Hcl, Analytical Standard

106. L-arginine Monohydrochloride, Not Synthetic, Meets Ep, Jp, Usp Testing Specifications, Suitable For Cell Culture, 98.5-101.0%

107. L-arginine Monohydrochloride, Pharmagrade, Ajinomoto, Ep, Jp, Usp, Manufactured Under Appropriate Gmp Controls For Pharma Or Biopharmaceutical Production, Suitable For Cell Culture

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 210.66 g/mol
Molecular Formula C6H15ClN4O2
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Exact Mass210.0883534 g/mol
Monoisotopic Mass210.0883534 g/mol
Topological Polar Surface Area128 Ų
Heavy Atom Count13
Formal Charge0
Complexity176
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameR-gene 10
Active IngredientArginine hydrochloride
Dosage FormInjectable
RouteInjection
Strength10gm/100ml
Market StatusPrescription
CompanyPharmacia And Upjohn

2 of 2  
Drug NameR-gene 10
Active IngredientArginine hydrochloride
Dosage FormInjectable
RouteInjection
Strength10gm/100ml
Market StatusPrescription
CompanyPharmacia And Upjohn

5 Pharmacology and Biochemistry
5.1 ATC Code

B - Blood and blood forming organs

B05 - Blood substitutes and perfusion solutions

B05X - I.v. solution additives

B05XB - Amino acids

B05XB01 - Arginine hydrochloride


API SUPPLIERS

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Pfanstiehl

U.S.A

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AVT (Shanghai)

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Antibioticos do Brasil Ltda

Brazil

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Antibioticos do Brasil Ltda

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Fresenius Kabi AB Brunna

Sweden

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Kyowa Hakko Bio

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Kyowa Hakko Bio

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Sandoz B2B

Switzerland

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Sandoz B2B

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Antibioticos do Brasil Ltda

Brazil

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Antibioticos do Brasil Ltda

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Mitsubishi Tanabe Pharma

Japan

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Mitsubishi Tanabe Pharma

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CordenPharma

Germany

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CordenPharma

Germany

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SIGMA TAU

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SIGMA TAU

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FDF Dossiers

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01

Adcock Ingram

South Africa
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Adcock Ingram

South Africa
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Arginine hydrochloride

Brand Name : Nutrineal PD4 with 1.1% amino acids

Dosage Form : SOL

Dosage Strength : 152mg/1000ml

Packaging : 2500X1g/1000ml

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

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Pfizer Inc

U.S.A
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Pfizer Inc

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ARGININE HYDROCHLORIDE

Brand Name : R-GENE 10

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 10GM/100ML

Packaging :

Approval Date : 1982-01-01

Application Number : 16931

Regulatory Info : RX

Registration Country : USA

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Sandoz B2B

Switzerland
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Sandoz B2B

Switzerland
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ARGININE HYDROCHLORIDE

Brand Name : L-ARGININE HYDROCHLORIDE INJECTION

Dosage Form : LIQUID

Dosage Strength : 250MG/ML

Packaging : 1X30ML

Approval Date :

Application Number : 399736

Regulatory Info : Ethical

Registration Country : Canada

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Serene Pharma

Uzbekistan
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Serene Pharma

Uzbekistan
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L-Arginine Hydrochloride API

Brand Name : Arginal

Dosage Form : Infusion

Dosage Strength : 4.2GM/100ML

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Approval Date :

Application Number :

Regulatory Info :

Registration Country : Uzbekistan

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Serene Pharma

Uzbekistan
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Serene Pharma

Uzbekistan
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L-Arginine Hydrochloride API

Brand Name : Argin

Dosage Form : Syrup

Dosage Strength : 1000MG/15ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Uzbekistan

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FDA Orange Book

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ARGININE HYDROCHLORIDE

Brand Name : R-GENE 10

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 10GM/100ML

Approval Date : 1982-01-01

Application Number : 16931

RX/OTC/DISCN : RX

RLD : Yes

TE Code :

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Canada

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ARGININE HYDROCHLORIDE

Brand Name : L-ARGININE HYDROCHLORIDE INJECTION

Dosage Form : LIQUID

Dosage Strength : 250MG/ML

Packaging : 1X30ML

Approval Date :

Application Number : 399736

Regulatory Info : Ethical

Registration Country : Canada

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