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Also known as: Arginine vasopressin, 113-79-1, Argipressine, Pitressin, Beta-hypophamine, 8-arginine-vasopressin
Molecular Formula
C46H65N15O12S2
Molecular Weight
1084.2  g/mol
InChI Key
KBZOIRJILGZLEJ-LGYYRGKSSA-N

Arginine Vasopressin
The predominant form of mammalian antidiuretic hormone. It is a nonapeptide containing an ARGININE at residue 8 and two disulfide-linked cysteines at residues of 1 and 6. Arg-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.
1 2D Structure

Arginine Vasopressin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
2.1.2 InChI
InChI=1S/C46H65N15O12S2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)/t27-,28-,29-,30-,31-,32-,33-,34-/m0/s1
2.1.3 InChI Key
KBZOIRJILGZLEJ-LGYYRGKSSA-N
2.1.4 Canonical SMILES
C1CC(N(C1)C(=O)C2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N
2.1.5 Isomeric SMILES
C1C[C@H](N(C1)C(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Arg Vasopressin

2. Arg-vasopressin

3. Arginine Vasopressin

4. Argipressin Tannate

5. Vasopressin, Arginine

2.2.2 Depositor-Supplied Synonyms

1. Arginine Vasopressin

2. 113-79-1

3. Argipressine

4. Pitressin

5. Beta-hypophamine

6. 8-arginine-vasopressin

7. Argipressin Tannate

8. Vasopressin (arginine Form)

9. Arginine-vasopressin

10. Chebi:34543

11. Vasophysin

12. Arg-vasopressin

13. Chembl373742

14. (arg8)-vasopressin

15. [arg8]-vasopressin

16. (2s)-1-[(4r,7s,10s,13s,16s,19r)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-n-[(2s)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide

17. 8-l-arginine Vasopressin

18. Argipresina

19. Argipressina

20. Argipressinum

21. Avp

22. Arg8-vasopressin

23. Argipressin [inn]

24. Argipressina [dcit]

25. Ncgc00166306-01

26. Argipressin [inn:ban]

27. 8-l-arginine-vasopressin

28. Argipresina [inn-spanish]

29. Argipressine [inn-french]

30. Argipressinum [inn-latin]

31. Unii-y4907o6mfd

32. Rindervasopressin

33. [3h]vasopressin

34. Einecs 204-035-4

35. 3-(phenylalanine)-8-arginineoxytocin

36. Arg8-vasopressin;avp

37. Arginine-8-vasopressin

38. Argipressin Or Lypressin

39. [8-arginine]vasopressin

40. [3h]argipressin Tannate

41. Antidiuretic Hormone (adh)

42. Arginine Vasopressin (avp)

43. Argipressin Tannate [usan]

44. Arginine Antidiuretic Hormone

45. Dsstox_cid_28324

46. Dsstox_rid_82752

47. Dsstox_gsid_48349

48. Schembl43139

49. Vasopressin, 8-l-arginine-

50. [cyclo S-s]cyfqncprg-nh2

51. Gtpl2168

52. Y4907o6mfd

53. Dtxsid0048349

54. Schembl17874853

55. Bdbm35667

56. Tox21_113037

57. Bdbm50044777

58. Mfcd00076738

59. Ncgc00166306-02

60. Ncgc00188439-01

61. Cas-113-79-1

62. H-cys-tyr-phe-gln-asn-cys-pro-arg-gly-nh2

63. Oxytocin, 3-(l-phenylalanine)-8-l-arginine-

64. Vasopressin, 8-l-arginine- (7ci,8ci,9ci)

65. Roxybenzyl-6,9,12,15,18-pentaoxo- (6ci)

66. 113a791

67. Q183011

68. Cys-tyr-phe-gln-asn-cys-pro-arg-gly-nh2[disulfide Bridge: 1-6]

69. (2s)-1-[(4r,7s,10s,13s,16s,19r)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-n-[(2s)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide

70. 1,2-dithia-5,8,11,14,17-pentaazacycloeicosane-10-propionamide, 19-amino-13-benzyl-7-(carbamoylmethyl)-4-[2-[[1-[(carbamoylmethyl)carbamoyl]-4-guanidinobutyl]carbamoyl]-1-pyrrolidinylcarbonyl]-16-p-hyd

71. 1-{[(4r,7s,10s,13s,16s,19r)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-l-prolyl-l-arginylglycinamide

72. Glycinamide, L-cysteinyl-l-tyrosyl-l-phenylalanyl-l-glutaminyl-l-asparaginyl-l-cysteinyl-l-prolyl-l-arginyl-, Cyclic (1>6)-disulfide

2.3 Create Date
2005-06-01
3 Chemical and Physical Properties
Molecular Weight 1084.2 g/mol
Molecular Formula C46H65N15O12S2
XLogP3-4.8
Hydrogen Bond Donor Count14
Hydrogen Bond Acceptor Count16
Rotatable Bond Count19
Exact Mass1083.43785492 g/mol
Monoisotopic Mass1083.43785492 g/mol
Topological Polar Surface Area515 Ų
Heavy Atom Count75
Formal Charge0
Complexity2070
Isotope Atom Count0
Defined Atom Stereocenter Count8
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Vasoconstrictor Agents

Drugs used to cause constriction of the blood vessels. (See all compounds classified as Vasoconstrictor Agents.)


Antidiuretic Agents

Agents that reduce the excretion of URINE, most notably the octapeptide VASOPRESSINS. (See all compounds classified as Antidiuretic Agents.)


Hemostatics

Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure. (See all compounds classified as Hemostatics.)


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20-Feb-2025
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ABOUT THIS PAGE

Looking for 113-79-1 / Arginine Vasopressin API manufacturers, exporters & distributors?

Arginine Vasopressin manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Arginine Vasopressin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Arginine Vasopressin manufacturer or Arginine Vasopressin supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Arginine Vasopressin manufacturer or Arginine Vasopressin supplier.

PharmaCompass also assists you with knowing the Arginine Vasopressin API Price utilized in the formulation of products. Arginine Vasopressin API Price is not always fixed or binding as the Arginine Vasopressin Price is obtained through a variety of data sources. The Arginine Vasopressin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Arginine Vasopressin

Synonyms

113-79-1, Argipressine, Pitressin, Beta-hypophamine, 8-arginine-vasopressin, Argipressin tannate

Cas Number

113-79-1

About Arginine Vasopressin

The predominant form of mammalian antidiuretic hormone. It is a nonapeptide containing an ARGININE at residue 8 and two disulfide-linked cysteines at residues of 1 and 6. Arg-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.

Argipressin Manufacturers

A Argipressin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Argipressin, including repackagers and relabelers. The FDA regulates Argipressin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Argipressin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Argipressin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Argipressin Suppliers

A Argipressin supplier is an individual or a company that provides Argipressin active pharmaceutical ingredient (API) or Argipressin finished formulations upon request. The Argipressin suppliers may include Argipressin API manufacturers, exporters, distributors and traders.

click here to find a list of Argipressin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Argipressin USDMF

A Argipressin DMF (Drug Master File) is a document detailing the whole manufacturing process of Argipressin active pharmaceutical ingredient (API) in detail. Different forms of Argipressin DMFs exist exist since differing nations have different regulations, such as Argipressin USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Argipressin DMF submitted to regulatory agencies in the US is known as a USDMF. Argipressin USDMF includes data on Argipressin's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Argipressin USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Argipressin suppliers with USDMF on PharmaCompass.

Argipressin NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Argipressin as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Argipressin API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Argipressin as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Argipressin and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Argipressin NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Argipressin suppliers with NDC on PharmaCompass.

Argipressin GMP

Argipressin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Argipressin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Argipressin GMP manufacturer or Argipressin GMP API supplier for your needs.

Argipressin CoA

A Argipressin CoA (Certificate of Analysis) is a formal document that attests to Argipressin's compliance with Argipressin specifications and serves as a tool for batch-level quality control.

Argipressin CoA mostly includes findings from lab analyses of a specific batch. For each Argipressin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Argipressin may be tested according to a variety of international standards, such as European Pharmacopoeia (Argipressin EP), Argipressin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Argipressin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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