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Chemistry

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Also known as: Aristolochic acid a, 313-67-7, Aristolochic acid i, Aristolochin, Tardolyt, Aristolochic acid-i
Molecular Formula
C17H11NO7
Molecular Weight
341.27  g/mol
InChI Key
BBFQZRXNYIEMAW-UHFFFAOYSA-N
FDA UNII
94218WFP5T

Aristolochic Acid
birthwort is a natural product found in Thottea duchartrei, Aristolochia, and other organisms with data available.
1 2D Structure

Aristolochic Acid

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
8-methoxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid
2.1.2 InChI
InChI=1S/C17H11NO7/c1-23-12-4-2-3-8-9(12)5-11(18(21)22)14-10(17(19)20)6-13-16(15(8)14)25-7-24-13/h2-6H,7H2,1H3,(H,19,20)
2.1.3 InChI Key
BBFQZRXNYIEMAW-UHFFFAOYSA-N
2.1.4 Canonical SMILES
COC1=CC=CC2=C3C(=C(C=C21)[N+](=O)[O-])C(=CC4=C3OCO4)C(=O)O
2.2 Other Identifiers
2.2.1 UNII
94218WFP5T
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 8-methoxy-6-nitrophenanthro(3,4-d)-1,3-dioxole-5-carboxylic Acid

2. Aristolochic Acid A

3. Aristolochic Acid I

4. Aristolochic Acid I, Sodium Salt

5. Sodium Aristolochate

6. Tardolyt

2.3.2 Depositor-Supplied Synonyms

1. Aristolochic Acid A

2. 313-67-7

3. Aristolochic Acid I

4. Aristolochin

5. Tardolyt

6. Aristolochic Acid-i

7. Aristolochine

8. Tr 1736

9. Nsc-50413

10. 8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic Acid

11. Nsc11926

12. 3,4-methylenedioxy-8-methoxy-10-nitro-1-phenanthrenecarboxylic Acid

13. 8-methoxy-3,4-methylenedioxy-10-nitrophenanthrene-1-carboxylic Acid

14. Nsc50413

15. Birthwort

16. 8-methoxy-6-nitrophenanthol (3,4-d) 1,3-dioxole-5-carboxylic Acid

17. Chembl93353

18. Mls002702976

19. Chebi:2825

20. Aristolochic Acid I;tr 1736

21. 94218wfp5t

22. Phenanthro(3,4-d)-1,3-dioxole-5-carboxylic Acid, 8-methoxy-6-nitro-

23. Phenanthro[3,4-d]-1,3-dioxole-5-carboxylic Acid, 8-methoxy-6-nitro-

24. Nsc-11926

25. 8-methoxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylic Acid

26. Aristolochiazaeure

27. 8-methoxy-6-nitro-naphtho[1,2-e][1,3]benzodioxole-5-carboxylic Acid

28. 8-methoxy-6-nitrophenanthrol(3,4-d)-1,3-dioxide-5-carboxylic Acid

29. Smr001562128

30. Aristolochic Acid 1

31. Ccris 1544

32. Sr-05000002369

33. Einecs 206-238-3

34. Nsc 11926

35. Nsc 50413

36. Brn 0345159

37. Aristolochia

38. Phenanthro[3,3-dioxole-5-carboxylic Acid, 8-methoxy-6-nitro-

39. Unii-94218wfp5t

40. Aristolochicacida

41. Aris-tolochic Acid

42. Goq

43. Aristolochic-acid-a

44. Mfcd00004996

45. Aristolochia A

46. Spectrum_001156

47. Specplus_000448

48. 8-methoxy-3,4-methylendioxxy-10-nitro-1-phenanthrencarbonsaeure

49. 8-methoxy-6-nitrophenanthro(3,4-d)-1,3-dioxole-5-carboxylic Acid

50. Spectrum2_000822

51. Spectrum3_001114

52. Spectrum4_001952

53. Spectrum5_000729

54. Aristolochic Acid A,(s)

55. Zinc52

56. Ncimech_000812

57. Aristolochic Acid I, Powder

58. Bspbio_001440

59. Bspbio_002848

60. Kbiogr_000160

61. Kbiogr_002387

62. Kbioss_000160

63. Kbioss_001636

64. Mls002695974

65. Divk1c_006544

66. Schembl166284

67. Spectrum1502233

68. Spbio_000743

69. Aristolochic Acid [mi]

70. Aristolochic Acid [iarc]

71. Dtxsid0040969

72. Kbio1_001488

73. Kbio2_000160

74. Kbio2_001636

75. Kbio2_002728

76. Kbio2_004204

77. Kbio2_005296

78. Kbio2_006772

79. Kbio3_000319

80. Kbio3_000320

81. Kbio3_002068

82. Bio1_000418

83. Bio1_000907

84. Bio1_001396

85. Bio2_000160

86. Bio2_000640

87. Hms1361h22

88. Hms1791h22

89. Hms1989h22

90. Hms3402h22

91. Aristolochic Acid [who-dd]

92. Hy-n0510

93. Tnp00273

94. 8-methoxy-6-nitro-naphtho[2,1-g][1,3]benzodioxole-5-carboxylic Acid

95. Bdbm50306855

96. Ccg-35796

97. Ccg-36162

98. S9193

99. Mixture Of Aristolochic Acid A And B

100. Akos015896751

101. Tr-1736

102. Idi1_033910

103. 2-naphthyl Pyrovalerone-d8 Hydrochloride

104. Ncgc00017334-01

105. Ncgc00017334-02

106. Ncgc00017334-03

107. Ncgc00017334-04

108. Ncgc00017334-05

109. Ncgc00017334-06

110. Ncgc00017334-07

111. Ncgc00095981-01

112. Ncgc00095981-02

113. Ncgc00095981-03

114. Ncgc00095981-04

115. Ncgc00095981-05

116. 1246815-48-4

117. Ac-34489

118. Bs-16911

119. Nci60_000460

120. Xa167153

121. Db-048017

122. Cs-0009050

123. Ft-0602867

124. N2032

125. C08469

126. 313a677

127. Aristolochic Acid, Plants Containing [iarc]

128. Q-100394

129. Sr-05000002369-2

130. Sr-05000002369-3

131. Q21099362

132. Aristolochia, European Pharmacopoeia (ep) Reference Standard

133. 8-methoxy-6-nitro-phenanthro[3,4-d][1,3]dioxole-5-carboxylic Acid

134. Aristolochic Acid I, European Pharmacopoeia (ep) Reference Standard

135. 8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic Acid #

136. Phenanthro[3,4-d]-1,3-dioxole-5-carbocylic Acid, 8-methoxy-6-nitro-

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 341.27 g/mol
Molecular Formula C17H11NO7
XLogP33.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count2
Exact Mass341.05355169 g/mol
Monoisotopic Mass341.05355169 g/mol
Topological Polar Surface Area111 Ų
Heavy Atom Count25
Formal Charge0
Complexity550
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Mutagens

Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes. (See all compounds classified as Mutagens.)


Carcinogens

Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included. (See all compounds classified as Carcinogens.)


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PharmaCompass also assists you with knowing the Aristolochic Acid API Price utilized in the formulation of products. Aristolochic Acid API Price is not always fixed or binding as the Aristolochic Acid Price is obtained through a variety of data sources. The Aristolochic Acid Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Aristolochic Acid

Synonyms

Aristolochic acid a, 313-67-7, Aristolochic acid i, Aristolochin, Tardolyt, Aristolochic acid-i

Cas Number

313-67-7

Unique Ingredient Identifier (UNII)

94218WFP5T

About Aristolochic Acid

birthwort is a natural product found in Thottea duchartrei, Aristolochia, and other organisms with data available.

Aristolochic Acid Manufacturers

A Aristolochic Acid manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Aristolochic Acid, including repackagers and relabelers. The FDA regulates Aristolochic Acid manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Aristolochic Acid API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Aristolochic Acid Suppliers

A Aristolochic Acid supplier is an individual or a company that provides Aristolochic Acid active pharmaceutical ingredient (API) or Aristolochic Acid finished formulations upon request. The Aristolochic Acid suppliers may include Aristolochic Acid API manufacturers, exporters, distributors and traders.

Aristolochic Acid GMP

Aristolochic Acid Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Aristolochic Acid GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Aristolochic Acid GMP manufacturer or Aristolochic Acid GMP API supplier for your needs.

Aristolochic Acid CoA

A Aristolochic Acid CoA (Certificate of Analysis) is a formal document that attests to Aristolochic Acid's compliance with Aristolochic Acid specifications and serves as a tool for batch-level quality control.

Aristolochic Acid CoA mostly includes findings from lab analyses of a specific batch. For each Aristolochic Acid CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Aristolochic Acid may be tested according to a variety of international standards, such as European Pharmacopoeia (Aristolochic Acid EP), Aristolochic Acid JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Aristolochic Acid USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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