Find ASLAN-002 manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

API REF. PRICE (USD/KG)

$
$ 0

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Regulatory FDF Prices

NA

API/FDF Prices: Book a Demo to
explore the features and consider
upgrading later

MARKET PLACE

0

API

0

FDF

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: Bms-777607, 1025720-94-8, Bms 777607, 1196681-44-3, Bms777607, Aslan-002
Molecular Formula
C25H19ClF2N4O4
Molecular Weight
512.9  g/mol
InChI Key
VNBRGSXVFBYQNN-UHFFFAOYSA-N
FDA UNII
A3MMS6HDO1

ASLAN-002
MET Tyrosine Kinase Inhibitor BMS-777607 is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. MET tyrosine kinase inhibitor BMS-777607 binds to c-Met protein, or hepatocyte growth factor receptor (HGFR), preventing binding of hepatocyte growth factor (HGF) and disrupting the MET signaling pathway; this agent may induce cell death in tumor cells expressing c-Met. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays an important role in tumor cell proliferation, survival, invasion, and metastasis, and in tumor angiogenesis.
1 2D Structure

ASLAN-002

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-[4-(2-amino-3-chloropyridin-4-yl)oxy-3-fluorophenyl]-4-ethoxy-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide
2.1.2 InChI
InChI=1S/C25H19ClF2N4O4/c1-2-35-19-10-12-32(16-6-3-14(27)4-7-16)25(34)21(19)24(33)31-15-5-8-18(17(28)13-15)36-20-9-11-30-23(29)22(20)26/h3-13H,2H2,1H3,(H2,29,30)(H,31,33)
2.1.3 InChI Key
VNBRGSXVFBYQNN-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCOC1=C(C(=O)N(C=C1)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F
2.2 Other Identifiers
2.2.1 UNII
A3MMS6HDO1
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Bms 777607

2. Bms-777607

3. Bms777607

4. N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide

2.3.2 Depositor-Supplied Synonyms

1. Bms-777607

2. 1025720-94-8

3. Bms 777607

4. 1196681-44-3

5. Bms777607

6. Aslan-002

7. Aslan002

8. N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide

9. A3mms6hdo1

10. N-[4-(2-amino-3-chloropyridin-4-yl)oxy-3-fluorophenyl]-4-ethoxy-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide

11. Bms 817378

12. 3-pyridinecarboxamide, N-[4-[(2-amino-3-chloro-4-pyridinyl)oxy]-3-fluorophenyl]-4-ethoxy-1-(4-fluorophenyl)-1,2-dihydro-2-oxo-

13. N-[4-[(2-amino-3-chloropyridin-4-yl)oxy]-3-fluorophenyl]-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide

14. N-{4-[(2-amino-3-chloropyridin-4-yl)oxy]-3-fluorophenyl}-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide

15. 3-pyridinecarboxamide, N-[4-[(2-amino-3-chloro-4-pyridinyl)oxy]-3-fluorophenyl]-4-ethoxy-1-(4-fluorophenyl)-1,2-dihydro-2-oxo-;3-pyridinecarboxamide, N-[4-[(2-amino-3-chloro-4-pyridinyl)oxy]-3-fluorophenyl]-4-ethoxy-1-(4-fluorophenyl)-1,2-dihydro-2-oxo-

16. N-(4-((2-amino-3-chloropyridin-4-yl)oxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide.

17. Unii-a3mms6hdo1

18. 3-pyridinecarboxamide, N-(4-((2-amino-3-chloro-4-pyridinyl)oxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-1,2-dihydro-2-oxo-

19. Mls006010958

20. N-{4-[(2-amino-3-chloro-4-pyridinyl)oxy]-3-fluorophenyl}-4-ethoxy -1-(4-fluorophenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide

21. Chembl460702

22. Gtpl7953

23. Schembl2588311

24. Bdbm28031

25. Chebi:91409

26. Dtxsid50145278

27. Ex-a004

28. 3f82

29. Hms3295i07

30. Hms3655c05

31. Amy24190

32. Bcp02303

33. Bcp13190

34. Bms777606

35. Mfcd16495773

36. Nsc764090

37. Nsc799365

38. S1561

39. Zinc39716080

40. Akos026750587

41. Bcp9000432

42. Ccg-264913

43. Cs-0227

44. Db12064

45. Ex-7213

46. Nsc-764090

47. Nsc-799365

48. Sb16607

49. Ncgc00263157-01

50. Ncgc00263157-09

51. Ac-30912

52. Ac-31421

53. As-17034

54. Da-35016

55. Hy-12076

56. N-[4-[(2-amino-3-chloro-4-pyridinyl)oxy]-3-fluorophenyl]-4-ethoxy-1-(4-fluorophenyl)-1,2-dihydro-2-oxo-3-pyridinecarboxamide

57. Smr004702762

58. Bms-777607;bms777607

59. Ft-0701277

60. Ft-0722977

61. Sw219298-1

62. A25030

63. Bms-777607, >=98% (hplc)

64. J-004169

65. J-523337

66. Brd-k40738845-001-01-9

67. Q27075371

68. N-(4-(2-amino-3-chloropyridin-4-yloxy )-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide

69. N-[4-[(2-amino-3-chloropyridin-4-yl)oxy]-3-fluorophenyl]-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide;bms-817378;bms-777607

2.4 Create Date
2008-05-26
3 Chemical and Physical Properties
Molecular Weight 512.9 g/mol
Molecular Formula C25H19ClF2N4O4
XLogP34
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Exact Mass512.1062891 g/mol
Monoisotopic Mass512.1062891 g/mol
Topological Polar Surface Area107 Ų
Heavy Atom Count36
Formal Charge0
Complexity867
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 1025720-94-8 / ASLAN-002 API manufacturers, exporters & distributors?

ASLAN-002 manufacturers, exporters & distributors 1

91

PharmaCompass offers a list of ASLAN-002 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right ASLAN-002 manufacturer or ASLAN-002 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred ASLAN-002 manufacturer or ASLAN-002 supplier.

PharmaCompass also assists you with knowing the ASLAN-002 API Price utilized in the formulation of products. ASLAN-002 API Price is not always fixed or binding as the ASLAN-002 Price is obtained through a variety of data sources. The ASLAN-002 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

ASLAN-002

Synonyms

Bms-777607, 1025720-94-8, Bms 777607, 1196681-44-3, Bms777607, Aslan002

Cas Number

1025720-94-8

Unique Ingredient Identifier (UNII)

A3MMS6HDO1

About ASLAN-002

MET Tyrosine Kinase Inhibitor BMS-777607 is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. MET tyrosine kinase inhibitor BMS-777607 binds to c-Met protein, or hepatocyte growth factor receptor (HGFR), preventing binding of hepatocyte growth factor (HGF) and disrupting the MET signaling pathway; this agent may induce cell death in tumor cells expressing c-Met. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays an important role in tumor cell proliferation, survival, invasion, and metastasis, and in tumor angiogenesis.

ASLAN-002 Manufacturers

A ASLAN-002 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of ASLAN-002, including repackagers and relabelers. The FDA regulates ASLAN-002 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. ASLAN-002 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

ASLAN-002 Suppliers

A ASLAN-002 supplier is an individual or a company that provides ASLAN-002 active pharmaceutical ingredient (API) or ASLAN-002 finished formulations upon request. The ASLAN-002 suppliers may include ASLAN-002 API manufacturers, exporters, distributors and traders.

ASLAN-002 GMP

ASLAN-002 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of ASLAN-002 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right ASLAN-002 GMP manufacturer or ASLAN-002 GMP API supplier for your needs.

ASLAN-002 CoA

A ASLAN-002 CoA (Certificate of Analysis) is a formal document that attests to ASLAN-002's compliance with ASLAN-002 specifications and serves as a tool for batch-level quality control.

ASLAN-002 CoA mostly includes findings from lab analyses of a specific batch. For each ASLAN-002 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

ASLAN-002 may be tested according to a variety of international standards, such as European Pharmacopoeia (ASLAN-002 EP), ASLAN-002 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (ASLAN-002 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty