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Chemistry

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Also known as: 254877-67-3, Hmr-1766, Ataciguat [inn], Hmr1766, Qp166m390q, 5-chloro-2-[(5-chlorothiophen-2-yl)sulfonylamino]-n-(4-morpholin-4-ylsulfonylphenyl)benzamide
Molecular Formula
C21H19Cl2N3O6S3
Molecular Weight
576.5  g/mol
InChI Key
PQHLRGARXNPFCF-UHFFFAOYSA-N
FDA UNII
QP166M390Q

Ataciguat
Ataciguat has been investigated for the basic science of Aortic Valve Stenosis.
1 2D Structure

Ataciguat

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5-chloro-2-[(5-chlorothiophen-2-yl)sulfonylamino]-N-(4-morpholin-4-ylsulfonylphenyl)benzamide
2.1.2 InChI
InChI=1S/C21H19Cl2N3O6S3/c22-14-1-6-18(25-34(28,29)20-8-7-19(23)33-20)17(13-14)21(27)24-15-2-4-16(5-3-15)35(30,31)26-9-11-32-12-10-26/h1-8,13,25H,9-12H2,(H,24,27)
2.1.3 InChI Key
PQHLRGARXNPFCF-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1COCCN1S(=O)(=O)C2=CC=C(C=C2)NC(=O)C3=C(C=CC(=C3)Cl)NS(=O)(=O)C4=CC=C(S4)Cl
2.2 Other Identifiers
2.2.1 UNII
QP166M390Q
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 5-chloro-2-(5-chlorothiophene-2-sulfonylamino)-n-(4-(morpholine-4-sulfonyl)phenyl)benzamide

2. Hmr 1766

3. Hmr-1766

4. Hmr1766

2.3.2 Depositor-Supplied Synonyms

1. 254877-67-3

2. Hmr-1766

3. Ataciguat [inn]

4. Hmr1766

5. Qp166m390q

6. 5-chloro-2-[(5-chlorothiophen-2-yl)sulfonylamino]-n-(4-morpholin-4-ylsulfonylphenyl)benzamide

7. 5-chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-n-[4-(4-morpholinylsulfonyl)phenyl]benzamide

8. 5-chloro-2-((5-chloro-2-thienyl)sulfonylamino)-n-(4-(morpholin-4-ylsulfonyl)phenyl)benzamide

9. Dsstox_cid_28672

10. Dsstox_rid_82942

11. Dsstox_gsid_48746

12. Hmr 1766

13. Cas-254877-67-3

14. Unii-qp166m390q

15. 5-chloro-2-(5-chlorothiophene-2-sulfonylamino)-n-(4-(morpholine-4-sulfonyl)phenyl)benzamide

16. Ataciguat [who-dd]

17. Schembl491675

18. Gtpl5141

19. Chembl2107729

20. Dtxsid7048746

21. Zinc3612878

22. Tox21_113203

23. Tox21_113203_1

24. Db12805

25. Sb16944

26. Ncgc00249417-01

27. Ncgc00249417-02

28. Hy-17500

29. Cs-0009242

30. Ft-0662311

31. A911275

32. J-016012

33. Q27074574

34. 5-chloro-2-(5-chlorothiophene-2-sulfonamido)-n-[4-(morpholine-4-sulfonyl)phenyl]benzamide

2.4 Create Date
2005-08-09
3 Chemical and Physical Properties
Molecular Weight 576.5 g/mol
Molecular Formula C21H19Cl2N3O6S3
XLogP34.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count7
Exact Mass574.9813042 g/mol
Monoisotopic Mass574.9813042 g/mol
Topological Polar Surface Area167 Ų
Heavy Atom Count35
Formal Charge0
Complexity944
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Enzyme Activators

Compounds or factors that act on a specific enzyme to increase its activity. (See all compounds classified as Enzyme Activators.)


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Looking for 254877-67-3 / Ataciguat API manufacturers, exporters & distributors?

Ataciguat manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Ataciguat API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Ataciguat manufacturer or Ataciguat supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ataciguat manufacturer or Ataciguat supplier.

PharmaCompass also assists you with knowing the Ataciguat API Price utilized in the formulation of products. Ataciguat API Price is not always fixed or binding as the Ataciguat Price is obtained through a variety of data sources. The Ataciguat Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Ataciguat

Synonyms

254877-67-3, Hmr-1766, Ataciguat [inn], Hmr1766, Qp166m390q, 5-chloro-2-[(5-chlorothiophen-2-yl)sulfonylamino]-n-(4-morpholin-4-ylsulfonylphenyl)benzamide

Cas Number

254877-67-3

Unique Ingredient Identifier (UNII)

QP166M390Q

About Ataciguat

Ataciguat has been investigated for the basic science of Aortic Valve Stenosis.

Ataciguat Manufacturers

A Ataciguat manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ataciguat, including repackagers and relabelers. The FDA regulates Ataciguat manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ataciguat API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Ataciguat Suppliers

A Ataciguat supplier is an individual or a company that provides Ataciguat active pharmaceutical ingredient (API) or Ataciguat finished formulations upon request. The Ataciguat suppliers may include Ataciguat API manufacturers, exporters, distributors and traders.

Ataciguat GMP

Ataciguat Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ataciguat GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ataciguat GMP manufacturer or Ataciguat GMP API supplier for your needs.

Ataciguat CoA

A Ataciguat CoA (Certificate of Analysis) is a formal document that attests to Ataciguat's compliance with Ataciguat specifications and serves as a tool for batch-level quality control.

Ataciguat CoA mostly includes findings from lab analyses of a specific batch. For each Ataciguat CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ataciguat may be tested according to a variety of international standards, such as European Pharmacopoeia (Ataciguat EP), Ataciguat JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ataciguat USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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