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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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FDF

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Chemistry

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Also known as: Belladonnine sulfate, 510-25-8, Beta-belladonnine, Belladonna alkaloids, Nsc100797, 5878-33-1
Molecular Formula
C34H42N2O4
Molecular Weight
542.7  g/mol
InChI Key
GERIGMSHTUAXSI-UHFFFAOYSA-N

Belladonna Leaf Extract
Alkaloids obtained from various plants, especially the deadly nightshade (Atropa belladonna), variety acuminata; atropine, hyoscyamine and scopolamine are classical, specific antimuscarinic agents with many pharmacologic actions; used mainly as antispasmodics.
1 2D Structure

Belladonna Leaf Extract

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
bis(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 4-phenyl-2,3-dihydro-1H-naphthalene-1,4-dicarboxylate
2.1.2 InChI
InChI=1S/C34H42N2O4/c1-35-23-12-13-24(35)19-27(18-23)39-32(37)30-16-17-34(22-8-4-3-5-9-22,31-11-7-6-10-29(30)31)33(38)40-28-20-25-14-15-26(21-28)36(25)2/h3-11,23-28,30H,12-21H2,1-2H3
2.1.3 InChI Key
GERIGMSHTUAXSI-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN1C2CCC1CC(C2)OC(=O)C3CCC(C4=CC=CC=C34)(C5=CC=CC=C5)C(=O)OC6CC7CCC(C6)N7C
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Alkaloids, Belladonna

2. Belladonna Alkaloids

2.2.2 Depositor-Supplied Synonyms

1. Belladonnine Sulfate

2. 510-25-8

3. Beta-belladonnine

4. Belladonna Alkaloids

5. Nsc100797

6. 5878-33-1

7. Schembl6437603

8. Chembl3187149

9. Dtxsid10965277

10. Stk663541

11. Ncgc00160302-01

12. Bis(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 4-phenyl-2,3-dihydro-1h-naphthalene-1,4-dicarboxylate

13. Ncgc00160302-01!belladonnine

14. Ft-0622610

15. Bis(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 1-phenyltetralin-1,4-dicarboxylate

16. 1,2,3,4-tetrahydro-1-phenyl-1,4-naphthalenedicarboxylic Acid Bis(8-methyl-8-azabicyclo[3.2.1]oct-3-yl) Ester

17. Bis(8-methyl-8-azabicyclo[3.2.1]oct-3-yl) 1-phenyl-1,2,3,4-tetrahydronaphthalene-1,4-dicarboxylate

18. Sulfuric Acid Compound With Bis(8-methyl-8-azabicyclo[3.2.1]oct-3-yl) 1-phenyl-1,2,3,4-tetrahydro-1,4-naphthalenedicarboxylate (1:1)

2.3 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 542.7 g/mol
Molecular Formula C34H42N2O4
XLogP36
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Exact Mass542.31445783 g/mol
Monoisotopic Mass542.31445783 g/mol
Topological Polar Surface Area59.1 Ų
Heavy Atom Count40
Formal Charge0
Complexity922
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count6
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 ATC Code

A - Alimentary tract and metabolism

A03 - Drugs for functional gastrointestinal disorders

A03B - Belladonna and derivatives, plain

A03BA - Belladonna alkaloids, tertiary amines

A03BA04 - Belladonna total alkaloids


API SUPPLIERS

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01

Alchem International Private Ltd

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Medlab Asia & Asia Health
Not Confirmed
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothAlchem offers Phytochemical APIs for Pharmaceuticals, Cosmetics and Nutraceuticals// FDA-inspected and EU-GMP certified.

Flag India
Digital Content Digital Content
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
Alchem

02

Tenatra Chemie

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Medlab Asia & Asia Health
Not Confirmed
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothTenatra connects Indian manufacturers with global buyers through active partners in Germany, Switzerland, Belgium, Spain & Turkey.

Flag India
Digital Content Digital Content
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
Tenatra

03

Inga Pharmaceuticals

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health
Not Confirmed
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Inga Pharmaceuticals

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Medlab Asia & Asia Health
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC arrow-down KDMF VMF Others AUDIT
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04

Ransom Naturals Ltd

United Kingdom

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health
Not Confirmed
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Ransom Naturals Ltd

United Kingdom

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Medlab Asia & Asia Health
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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NDC API

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01

Medlab Asia & Asia Health
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Medlab Asia & Asia Health
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ATROPA BELLADONNA

NDC Package Code : 63570-010

Start Marketing Date : 2000-03-01

End Marketing Date : 2024-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT

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02

Medlab Asia & Asia Health
Not Confirmed
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Medlab Asia & Asia Health
Not Confirmed

ATROPA BELLADONNA

NDC Package Code : 51927-1120

Start Marketing Date : 2013-06-25

End Marketing Date : 2024-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT FOR HUMAN P...

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Listed Suppliers

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01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothAlchem offers Phytochemical APIs for Pharmaceuticals, Cosmetics and Nutraceuticals// FDA-inspected and EU-GMP certified.

Flag India
Digital Content Digital Content

Belladonna Leaf Extract

About the Company : Alchem International, established in 1935, is a pioneer in phytochemicals, providing plant-derived active pharmaceutical ingredients to the pharmaceutical, cosmetic and nutraceutic...

Alchem International, established in 1935, is a pioneer in phytochemicals, providing plant-derived active pharmaceutical ingredients to the pharmaceutical, cosmetic and nutraceutical industries. With over 75 years of experience, Alchem has established a global presence, selling its products in more than 35 countries. Alchem has three manufacturing sites spread across 62 acres in India and four international divisions with offices in India, Europe, Hong Kong and the US. Alchem has two divisions – Phytoceuticals and EpiQue – that provide healthcare and cosmetic products to the Indian market and employs over 1,000 people worldwide.
Alchem

02

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Antibody Engineering
Not Confirmed
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothTenatra connects Indian manufacturers with global buyers through active partners in Germany, Switzerland, Belgium, Spain & Turkey.

Flag India
Digital Content Digital Content

Belladonna Alkaloids

About the Company : Tenatra International was established as a proprietorship firm in 1999. It got off to a very good start, supporting clients in the United States, Mexico and Europe. As business opp...

Tenatra International was established as a proprietorship firm in 1999. It got off to a very good start, supporting clients in the United States, Mexico and Europe. As business opportunities grew, it was felt that the proprietorship firm had outlived its usefulness and that it needed a corporate structure. So, Tenatra Chemie Private Limited (TCPL) was incorporated in 2002. Since then, the company has come a long way, gaining valuable experience and knowledge in the fields of chemicals and pharmaceuticals in India.
Tenatra

03

Antibody Engineering
Not Confirmed
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Antibody Engineering
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Belladonna Alkaloids

About the Company : Inga Pharmaceuticals (Inga), established in 1980, is involved in the cultivation, isolation and extraction of actives from plant sources. The Corporate Office is located in Mumbai ...

Inga Pharmaceuticals (Inga), established in 1980, is involved in the cultivation, isolation and extraction of actives from plant sources. The Corporate Office is located in Mumbai & the manufacturing facility is located at Chennai. Plants required for the isolation of active principles are cultivated by the company at its own farms and those of its associates in India, Africa and the Americas. Inga has established excellent relations with it's customers in 60 countries through its dedicated service for the last 5 decades.
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04

Ransom Naturals Ltd

United Kingdom
Antibody Engineering
Not Confirmed
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Ransom Naturals Ltd

United Kingdom
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Antibody Engineering
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Atropa Belladonna L.

About the Company : Ransom Naturals Ltd (RNL) is a leading developer and manufacturer of natural products and extracts to the pharmaceutical, cosmetic and food & drinks industries.Our range includes a...

Ransom Naturals Ltd (RNL) is a leading developer and manufacturer of natural products and extracts to the pharmaceutical, cosmetic and food & drinks industries.Our range includes active pharmaceutical ingredients (APSs), excipients, over the counter medicines and products used to deliver flavour and functionality in food and drinks.
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