Find AUM001 manufacturers, exporters & distributors on PharmaCompass

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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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API Suppliers

API Suppliers

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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JDMF

JDMFs Filed

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

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Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

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MARKET PLACE

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API

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FDF

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FINISHED DOSAGE FORMULATIONS

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FDF Dossiers

FDF Dossiers

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FDA Orange Book

FDA (Orange Book)

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Europe

Europe

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Canada

Canada

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Australia

Australia

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South Africa

South Africa

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Listed Dossiers

Listed Dossiers

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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Others

PATENTS & EXCLUSIVITIES

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US Patents

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Data Compilation #PharmaFlow

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Stock Recap #PipelineProspector

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GLOBAL SALES INFORMATION

US Medicaid

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Annual Reports

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Finished Drug Prices

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0RELATED EXCIPIENT COMPANIES

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Chemistry

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Also known as: Etc-206, 1464151-33-4, Mnd3wx2r7i, Aum001, Aum-001, Etc1907206
Molecular Formula
C25H20N4O2
Molecular Weight
408.5  g/mol
InChI Key
FWRFPHJSGLYXTD-UHFFFAOYSA-N
FDA UNII
MND3WX2R7I

AUM001
MNK1/2 Inhibitor ETC-1907206 is a selective mitogen-activated protein kinase (MAPK)-interacting protein kinase (MNK) types 1/2 inhibitor with potential antineoplastic activity. Upon administration, MNK1/2 inhibitor ETC-1907206 may inhibit MNK1/2-dependent phosphorylation of eukaryotic initiation factor 4E (eIF4E) and interfere with its role in mRNA translation. eIF4E is an oncoprotein that must be phosphorylated before it can promote the proliferation and progression of tumor cells. MNKs are a family of serine/threonine kinases that have been implicated in oncogenic transformation and tumor progression.
1 2D Structure

AUM001

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]benzonitrile
2.1.2 InChI
InChI=1S/C25H20N4O2/c26-15-18-1-3-20(4-2-18)23-16-27-24-10-9-22(17-29(23)24)19-5-7-21(8-6-19)25(30)28-11-13-31-14-12-28/h1-10,16-17H,11-14H2
2.1.3 InChI Key
FWRFPHJSGLYXTD-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1COCCN1C(=O)C2=CC=C(C=C2)C3=CN4C(=NC=C4C5=CC=C(C=C5)C#N)C=C3
2.2 Other Identifiers
2.2.1 UNII
MND3WX2R7I
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Etc-206

2. 1464151-33-4

3. Mnd3wx2r7i

4. Aum001

5. Aum-001

6. Etc1907206

7. 4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]benzonitrile

8. Benzonitrile, 4-(6-(4-(4-morpholinylcarbonyl)phenyl)imidazo(1,2-a)pyridin-3-yl)-

9. Unii-mnd3wx2r7i

10. Etc206

11. Chembl4211649

12. Schembl15288605

13. Us9908886, Example 96

14. Bdbm375544

15. Bcp30906

16. Ex-a4504

17. Mfcd31692387

18. S6658

19. Etc-206 (aum 001)

20. Hy-112424

21. Cs-0046041

22. Etc 206; Etc206;etc-1907206

2.4 Create Date
2013-11-04
3 Chemical and Physical Properties
Molecular Weight 408.5 g/mol
Molecular Formula C25H20N4O2
XLogP33.9
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass408.15862589 g/mol
Monoisotopic Mass408.15862589 g/mol
Topological Polar Surface Area70.6 Ų
Heavy Atom Count31
Formal Charge0
Complexity668
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

AUM001 Manufacturers

A AUM001 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of AUM001, including repackagers and relabelers. The FDA regulates AUM001 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. AUM001 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

AUM001 Suppliers

A AUM001 supplier is an individual or a company that provides AUM001 active pharmaceutical ingredient (API) or AUM001 finished formulations upon request. The AUM001 suppliers may include AUM001 API manufacturers, exporters, distributors and traders.

AUM001 GMP

AUM001 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of AUM001 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right AUM001 GMP manufacturer or AUM001 GMP API supplier for your needs.

AUM001 CoA

A AUM001 CoA (Certificate of Analysis) is a formal document that attests to AUM001's compliance with AUM001 specifications and serves as a tool for batch-level quality control.

AUM001 CoA mostly includes findings from lab analyses of a specific batch. For each AUM001 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

AUM001 may be tested according to a variety of international standards, such as European Pharmacopoeia (AUM001 EP), AUM001 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (AUM001 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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