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1. Aumolertinib
2. Hs-10296
3. N-(5-((4-(1-cyclopropylindol-3-yl)pyrimidin-2-yl)amino)-2-(2-(dimethylamino)ethyl-methylamino)-4-methoxyphenyl)prop-2-enamide
1. Hs-10296
2. 1899921-05-1
3. Aumolertinib
4. Ameile
5. Aumolertinib [usan]
6. Hs-10297
7. Egfr T790m Inhibitor Hs-10296
8. Chembl4761468
9. T4rs462g19
10. N-(5-((4-(1-cyclopropyl-1h-indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide
11. 2-propenamide, N-(5-((4-(1-cyclopropyl-1h-indol-3-yl)-2-pyrimidinyl)amino)-2-((2-(dimethylamino)ethyl)methylamino)-4-methoxyphenyl)-
12. N-[5-[[4-(1-cyclopropylindol-3-yl)pyrimidin-2-yl]amino]-2-[2-(dimethylamino)ethyl-methylamino]-4-methoxyphenyl]prop-2-enamide
13. Aumolertinib [inn]
14. Almonertinib [who-dd]
15. Unii-t4rs462g19
16. Schembl17683063
17. Gtpl11136
18. Eq143
19. Ex-a3721
20. Zad92105
21. Hs 10296 [who-dd]
22. Bdbm50557548
23. Eq-143
24. S8817
25. Who 11295
26. At30756
27. Hs10296
28. As-84436
29. Example 26 [wo2016054987a1]
30. Hs-10206
31. Hy-112823
32. Cs-0066162
Molecular Weight | 525.6 g/mol |
---|---|
Molecular Formula | C30H35N7O2 |
XLogP3 | 4.2 |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 7 |
Rotatable Bond Count | 11 |
Exact Mass | 525.28522338 g/mol |
Monoisotopic Mass | 525.28522338 g/mol |
Topological Polar Surface Area | 87.6 Ų |
Heavy Atom Count | 39 |
Formal Charge | 0 |
Complexity | 823 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
Almonertinib inhibits EGFR tyrosine kinase targeting EGFR-sensitizing and T790M resistance mutations.
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