Synopsis
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1. Ag 013736
2. Ag-013736
3. Ag013736
4. Inlyta
1. 319460-85-0
2. Ag-013736
3. Inlyta
4. Ag 013736
5. (e)-n-methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1h-indazol-6-yl)thio)benzamide
6. Ag-13736
7. Ag013736
8. C9lvq0yuxg
9. N-methyl-2-((3-((1e)-2-(pyridin-2-yl)ethenyl)-1h-indazol-6-yl)sulfanyl)benzamide
10. Nsc-757441
11. Chebi:66910
12. (e)-n-methyl-2-(3-(2-(pyridin-2-yl)vinyl)-1h-indazol-6-ylthio)benzamide
13. N-methyl-2-[[3-[(e)-2-pyridin-2-ylethenyl]-1h-indazol-6-yl]sulfanyl]benzamide
14. Nsc757441
15. N-methyl-2-({3-[(e)-2-(pyridin-2-yl)ethenyl]-1h-indazol-6-yl}sulfanyl)benzamide
16. Ncgc00241108-01
17. S1005
18. Dsstox_cid_28975
19. Dsstox_rid_83240
20. Dsstox_gsid_49049
21. Axitinib (ag 013736)
22. N-methyl-2-({3-[(e)-2-(pyridin-2-yl)vinyl]-1h-indazol-6-yl}sulfanyl)benzamide
23. N-methyl-2-(3-((e)-2-pyridin-2-yl-vinyl)-1h-indazol-6-ylsulfanyl)-benzamide
24. Axitinib [usan]
25. Cas-319460-85-0
26. Unii-c9lvq0yuxg
27. Axitinibum
28. Axitinib [usan:inn:jan]
29. 4agc
30. Benzamide, N-methyl-2-((3-((1e)-2-(2-pyridinyl)ethenyl)-1h-indazol-6-yl)thio)-
31. Benzamide, N-methyl-2-[[3-[(1e)-2-(2-pyridinyl)ethenyl]-1h-indazol-6-yl]thio]-
32. Inlyta (tn)
33. Mfcd09837898
34. Ag13736
35. 4ag8
36. Axitinib (jan/usan)
37. Axitinib [inn]
38. Axitinib [jan]
39. Axitinib [mi]
40. Axitinib [vandf]
41. Axitinib [mart.]
42. Ag-013736;axitinib
43. Axitinib [who-dd]
44. Axitinib,ag-013736
45. Mls006010164
46. Schembl172918
47. Axitinib [orange Book]
48. Gtpl5659
49. Axitinib, >=98% (hplc)
50. Chembl1289926
51. Dtxsid3049049
52. N-methyl-2-[[3-[2-(2-pyridinyl)ethenyl]-1h-indazol-6-yl]thio]benzamide
53. Schembl22930506
54. Bdbm25117
55. Chebi:94568
56. Ex-a337
57. Bcpp000372
58. Bcp01371
59. Zinc3816287
60. Tox21_113597
61. Nsc799341
62. Akos015902898
63. Tox21_113597_1
64. Ac-1539
65. Bcp9000345
66. Ccg-264772
67. Cs-0116
68. Db06626
69. Ks-1448
70. Nsc 757441
71. Nsc-799341
72. Benzamide, N-methyl-2-((3-((e)-2-(2-pyridinyl)ethenyl)-1h-indazol-6-yl)thio)-
73. Ncgc00241108-04
74. Ncgc00241108-06
75. Hy-10065
76. Smr002530046
77. Am20090673
78. Sw219464-1
79. D03218
80. Ab01274739-01
81. Ab01274739_02
82. 460a850
83. Sr-01000941566
84. J-502064
85. Q-200662
86. Q4830631
87. Sr-01000941566-1
88. Brd-k29905972-001-01-4
89. Brd-k29905972-001-02-2
90. Benzamide, N-methyl-2-((3-((1e)-2-(2-pyridinyl)ethenyl)-1h-indazo)-6-yl)thio)-
91. N-methyl-[[3[(1e)-2-(2-pyridinyl)ethenyl]-1h-indazol-6-yl]thio]-benzamide
92. N-methyl-2((3-((1e0-2-(pyridin-2-yl)ethenyl)-1h-inazol-6-ylsufanyl)benzamide
93. N-methyl-2-({3-[(e)-2-pyridin-2-ylethenyl]-2h-indazol-6-yl}sulfanyl)benzamide
Molecular Weight | 386.5 g/mol |
---|---|
Molecular Formula | C22H18N4OS |
XLogP3 | 4.2 |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 4 |
Rotatable Bond Count | 5 |
Exact Mass | 386.12013238 g/mol |
Monoisotopic Mass | 386.12013238 g/mol |
Topological Polar Surface Area | 96 Ų |
Heavy Atom Count | 28 |
Formal Charge | 0 |
Complexity | 557 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 1 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
1 of 2 | |
---|---|
Drug Name | Inlyta |
PubMed Health | Axitinib (By mouth) |
Drug Classes | Antineoplastic Agent |
Drug Label | INLYTA (axitinib) is a kinase inhibitor. Axitinib has the chemical name N-methyl-2-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-ylsulfanyl]-benzamide. The molecular formula is C22H18N4OS and the molecular weight is 386.47 Daltons. The chemical structur... |
Active Ingredient | Axitinib |
Dosage Form | Tablet |
Route | Oral |
Strength | 1mg; 5mg |
Market Status | Prescription |
Company | Pfizer |
2 of 2 | |
---|---|
Drug Name | Inlyta |
PubMed Health | Axitinib (By mouth) |
Drug Classes | Antineoplastic Agent |
Drug Label | INLYTA (axitinib) is a kinase inhibitor. Axitinib has the chemical name N-methyl-2-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-ylsulfanyl]-benzamide. The molecular formula is C22H18N4OS and the molecular weight is 386.47 Daltons. The chemical structur... |
Active Ingredient | Axitinib |
Dosage Form | Tablet |
Route | Oral |
Strength | 1mg; 5mg |
Market Status | Prescription |
Company | Pfizer |
Used in kidney cell cancer and investigated for use/treatment in pancreatic and thyroid cancer.
FDA Label
Inlyta is indicated for the treatment of adult patients with advanced renal cell carcinoma (RCC) after failure of prior treatment with sunitinib or a cytokine.
Axitinib prevents the progression of cancer by inhibiting angiogenesis and blocking tumor growth.
Antineoplastic Agents
Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)
Protein Kinase Inhibitors
Agents that inhibit PROTEIN KINASES. (See all compounds classified as Protein Kinase Inhibitors.)
L01EK01
L01XE17
S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355
L - Antineoplastic and immunomodulating agents
L01 - Antineoplastic agents
L01E - Protein kinase inhibitors
L01EK - Vascular endothelial growth factor receptor (vegfr) tyrosine kinase inhibitors
L01EK01 - Axitinib
Absorption
After one 5 mg dose of axitinib, it takes about 2.5 to 4.1 hours to reach maximum plasma concentration.
Route of Elimination
Axitinib is mainly eliminated unchanged in the feces (41%) with 12% of the original dose as unchanged axitinib. There is also 23% eliminated in the urine, most of which are metabolites.
Volume of Distribution
The volume of distribution is 160 L.
Clearance
The average clearance of axitinib is 38 L/h.
Axitinib undergoes mainly hepatic metabolism. CYP3A4 and CYP3A5 are the main hepatic enzymes while CYP1A2, CYP2C19, and UGT1A1 enzymes are secondary.
Axitinib has a half life of 2.5 to 6.1 hours.
Axitinib selectively blocks the tyrosine kinase receptors VEGFR-1 (vascular endothelial growth factor receptor), VEGFR-2, and VEGFR-3.
GDUFA
DMF Review : Complete
Rev. Date : 2016-09-16
Pay. Date : 2016-07-01
DMF Number : 30341
Submission : 2016-03-04
Status : Active
Type : II
GDUFA
DMF Review : Complete
Rev. Date : 2015-12-18
Pay. Date : 2015-09-23
DMF Number : 29672
Submission : 2015-09-29
Status : Active
Type : II
GDUFA
DMF Review : Complete
Rev. Date : 2016-02-05
Pay. Date : 2015-12-23
DMF Number : 30104
Submission : 2015-12-24
Status : Active
Type : II
GDUFA
DMF Review : Complete
Rev. Date : 2023-06-27
Pay. Date : 2023-02-06
DMF Number : 37971
Submission : 2023-02-02
Status : Active
Type : II
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 39323
Submission : 2023-12-27
Status : Active
Type : II
GDUFA
DMF Review : Complete
Rev. Date : 2016-04-15
Pay. Date : 2015-10-29
DMF Number : 29918
Submission : 2015-10-10
Status : Active
Type : II
Date of Issue : 2022-06-17
Valid Till : 2025-07-02
Written Confirmation Number : WC-0082
Address of the Firm : API Division Kharakhadi, Plot No. 842-843, Kharakhadi, Padra Vadodara-391 450, G...
Date of Issue : 2022-09-16
Valid Till : 2025-08-08
Written Confirmation Number : WC-0041
Address of the Firm : Unit-I, Survey No.10, I.D.A, Gaddapotharam Village, Jinnaram Mandal,Medak Dist, ...
Date of Issue : 2019-09-03
Valid Till : 2022-08-08
Written Confirmation Number : WC-0041A3
Address of the Firm : Unit-I, Survey No.10, I.D.A, Gaddapotharam Village, Jinnaram Mandal,Medak Dist, ...
Date of Issue : 2022-09-02
Valid Till : 2025-05-05
Written Confirmation Number : WC-0349
Address of the Firm : MIs. MSN Laboratories Private Limited, Unit-II, sv. No, 50, Kardanur (Village), ...
Date of Issue : 2021-06-11
Valid Till : 2022-07-02
Written Confirmation Number : WC-0147A3
Address of the Firm : 100% EOU, Raichur Industrial Growth Centre, Plot No. 33, 33A, 40-47, Chicksugur-...
NDC Package Code : 54893-0043
Start Marketing Date : 2016-02-01
End Marketing Date : 2024-12-31
Dosage Form (Strength) : POWDER (1kg/kg)
Marketing Category : BULK INGREDIENT
NDC Package Code : 54893-0032
Start Marketing Date : 2014-12-23
End Marketing Date : 2024-12-31
Dosage Form (Strength) : POWDER (1kg/kg)
Marketing Category : BULK INGREDIENT
NDC Package Code : 82920-028
Start Marketing Date : 2022-08-15
End Marketing Date : 2024-12-31
Dosage Form (Strength) : POWDER (1kg/kg)
Marketing Category : BULK INGREDIENT
NDC Package Code : 65344-0033
Start Marketing Date : 2023-12-29
End Marketing Date : 2024-12-31
Dosage Form (Strength) : POWDER (1kg/kg)
Marketing Category : BULK INGREDIENT
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API Imports and Exports
Importing Country | Total Quantity (KGS) |
Average Price (USD/KGS) |
Number of Transactions |
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Details:
Axpaxli (axitinib) is an investigational bioresorbable, hydrogel implant with axitinib, small molecule TKI with anti-angiogenic properties. It is being developed for the treatment of wet AMD.
Lead Product(s): Axitinib
Therapeutic Area: Ophthalmology Brand Name: Axpaxli
Study Phase: Phase IIIProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable October 15, 2024
Lead Product(s) : Axitinib
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Ocular Therapeutix™ Speeds SOL-1 Trial of AXPAXLI™ in Wet AMD
Details : Axpaxli (axitinib) is an investigational bioresorbable, hydrogel implant with axitinib, small molecule TKI with anti-angiogenic properties. It is being developed for the treatment of wet AMD.
Brand Name : Axpaxli
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 15, 2024
Details:
CLS-AX (axitinib injectable suspension) is a tyrosine kinase inhibitor (TKI), is under Phase 2b clinical trial for the treatment of wet AMD.
Lead Product(s): Axitinib
Therapeutic Area: Ophthalmology Brand Name: CLS-AX
Study Phase: Phase IIProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable October 09, 2024
Lead Product(s) : Axitinib
Therapeutic Area : Ophthalmology
Highest Development Status : Phase II
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Clearside Announces Positive Results in ODYSSEY Phase 2b Trial For Wet AMD
Details : CLS-AX (axitinib injectable suspension) is a tyrosine kinase inhibitor (TKI), is under Phase 2b clinical trial for the treatment of wet AMD.
Brand Name : CLS-AX
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 09, 2024
Details:
CLS-AX (axitinib injectable suspension) is a tyrosine kinase inhibitor (TKI), is under Phase 2b clinical trial for the treatment of wet AMD.
Lead Product(s): Axitinib
Therapeutic Area: Ophthalmology Brand Name: CLS-AX
Study Phase: Phase IIProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable August 27, 2024
Lead Product(s) : Axitinib
Therapeutic Area : Ophthalmology
Highest Development Status : Phase II
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Clearside Biomedical Completes ODYSSEY Phase 2b Trial for CLS-AX in Wet AMD
Details : CLS-AX (axitinib injectable suspension) is a tyrosine kinase inhibitor (TKI), is under Phase 2b clinical trial for the treatment of wet AMD.
Brand Name : CLS-AX
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 27, 2024
Details:
Axpaxli (axitinib) is an investigational bioresorbable, hydrogel implant with axitinib, small molecule TKI with anti-angiogenic properties. It is being developed for the treatment of wet AMD.
Lead Product(s): Axitinib
Therapeutic Area: Ophthalmology Brand Name: Axpaxli
Study Phase: Phase IIIProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable August 07, 2024
Lead Product(s) : Axitinib
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Ocular Therapeutix™ Receives FDA Feedback on SOL-R Trial for Wet AMD
Details : Axpaxli (axitinib) is an investigational bioresorbable, hydrogel implant with axitinib, small molecule TKI with anti-angiogenic properties. It is being developed for the treatment of wet AMD.
Brand Name : Axpaxli
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 07, 2024
Details:
Axpaxli (axitinib) is an investigational bioresorbable, hydrogel implant incorporating axitinib, a small molecule, multi-target, tyrosine kinase inhibitor for the treatment of WET AMD.
Lead Product(s): Axitinib
Therapeutic Area: Ophthalmology Brand Name: Axpaxli
Study Phase: Phase IIIProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable July 30, 2024
Lead Product(s) : Axitinib
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Ocular Therapeutix™ Announces First Patients Enrolled in Phase 3 SOL-R Wet AMD Study
Details : Axpaxli (axitinib) is an investigational bioresorbable, hydrogel implant incorporating axitinib, a small molecule, multi-target, tyrosine kinase inhibitor for the treatment of WET AMD.
Brand Name : Axpaxli
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 30, 2024
Details:
Axpaxli (axitinib) is a bioresorbable hydrogel implant incorporating axitinib, a multi-target tyrosine kinase inhibitor, being developed for diabetic retinopathy treatment.
Lead Product(s): Axitinib
Therapeutic Area: Ophthalmology Brand Name: Axpaxli
Study Phase: Phase IProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable April 18, 2024
Lead Product(s) : Axitinib
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Ocular Therapeutix™ Announces Positive Phase 1 Data for AXPAXLI™ in Diabetic Retinopathy
Details : Axpaxli (axitinib) is a bioresorbable hydrogel implant incorporating axitinib, a multi-target tyrosine kinase inhibitor, being developed for diabetic retinopathy treatment.
Brand Name : Axpaxli
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 18, 2024
Details:
JS001 (toripalimab) is an anti-PD-1 monoclonal antibody developed for its ability to block PD-1 interactions. It is approved in combination with axitinib for the treatment of renal carcinoma.
Lead Product(s): Toripalimab,Axitinib
Therapeutic Area: Oncology Brand Name: Tuoyi
Study Phase: ApprovedProduct Type: Large molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable April 07, 2024
Lead Product(s) : Toripalimab,Axitinib
Therapeutic Area : Oncology
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Junshi Receives sNDA Approval for Toripalimab for First-Line Renal Cancer Treatment
Details : JS001 (toripalimab) is an anti-PD-1 monoclonal antibody developed for its ability to block PD-1 interactions. It is approved in combination with axitinib for the treatment of renal carcinoma.
Brand Name : Tuoyi
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 07, 2024
Details:
The company intends to use the net proceeds from the private placement to accelerate the clinical development of Axpali (axitinib) for the treatment of wet age-related macular degeneration.
Lead Product(s): Axitinib
Therapeutic Area: Ophthalmology Brand Name: Axpaxli
Study Phase: Phase IIIProduct Type: Small molecule
Sponsor: Venrock Healthcare Capital Partners
Deal Size: $325.0 million Upfront Cash: Undisclosed
Deal Type: Private Placement February 22, 2024
Lead Product(s) : Axitinib
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Venrock Healthcare Capital Partners
Deal Size : $325.0 million
Deal Type : Private Placement
Ocular Therapeutix, Inc. Announces $325.0 Million Private Placement
Details : The company intends to use the net proceeds from the private placement to accelerate the clinical development of Axpali (axitinib) for the treatment of wet age-related macular degeneration.
Brand Name : Axpaxli
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 22, 2024
Details:
Axpaxli (axitinib) is a bioresorbable hydrogel implant incorporating axitinib, developed for wet age-related macular degeneration treatment.
Lead Product(s): Axitinib
Therapeutic Area: Ophthalmology Brand Name: Axpaxli
Study Phase: Phase IIIProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable February 13, 2024
Lead Product(s) : Axitinib
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Ocular Therapeutix Announces First Subjects Screened in Phase 3 Trial Of AXPAXLI
Details : Axpaxli (axitinib) is a bioresorbable hydrogel implant incorporating axitinib, developed for wet age-related macular degeneration treatment.
Brand Name : Axpaxli
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 13, 2024
Details:
Axpaxli (axitinib) is an investigational hydrogel implant containing axitinib, being evaluated in phase 3 trials for treating wet AMD and other retinal diseases.
Lead Product(s): Axitinib
Therapeutic Area: Ophthalmology Brand Name: Axpaxli
Study Phase: Phase IIIProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable January 25, 2024
Lead Product(s) : Axitinib
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Ocular Therapeutix Amends SPA for AXPAXLI™ in Wet AMD Trial
Details : Axpaxli (axitinib) is an investigational hydrogel implant containing axitinib, being evaluated in phase 3 trials for treating wet AMD and other retinal diseases.
Brand Name : Axpaxli
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 25, 2024
CAS Number : 319460-85-0
End Use API : Axitinib
About The Company : Epoch-Labs is a Hyderabad, India based Research Organization that gives science administrations to expansive pharmaceutical organization, agrochemical organizat...
2-(1H-indazol-6-ylthio)-N-methyl-Benzamide
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End Use API : Axitinib
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6-Iodo-3(E)-2-pyridin-2-yl-vinyl)-1-(tetrahydropyr...
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End Use API : Axitinib
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End Use API : Axitinib
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CAS Number : 70315-70-7
End Use API : Axitinib
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2,2'-disulfanediylbis(N-methylbenzamide)
CAS Number : 2527-58-4
End Use API : Axitinib
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CAS Number : 20054-45-9
End Use API : Axitinib
About The Company : Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceu...
N -methyl-2 -sulfanylbenzamide
CAS Number : 20054-45-9
End Use API : Axitinib
About The Company : Established in 2011 and situated in Hangzhou, Zhejiang, China, Hangzhou Longshine Bio-Tech CO., Ltd is dedicated to providing services for pharmaceutical and ch...
3-Iodo-6-nitromdazole
CAS Number : 70315-70-7
End Use API : Axitinib
About The Company : Established in 2011 and situated in Hangzhou, Zhejiang, China, Hangzhou Longshine Bio-Tech CO., Ltd is dedicated to providing services for pharmaceutical and ch...
N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-in...
CAS Number : 319460-85-0
End Use API : Axitinib
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RLD :
TE Code :
Brand Name : AXITINIB
Dosage Form : TABLET;ORAL
Dosage Strength : 1MG
Approval Date :
Application Number : 211650
RX/OTC/DISCN :
RLD :
TE Code :
RLD :
TE Code :
Brand Name : AXITINIB
Dosage Form : TABLET;ORAL
Dosage Strength : 5MG
Approval Date :
Application Number : 211650
RX/OTC/DISCN :
RLD :
TE Code :
RLD : Yes
TE Code :
Brand Name : INLYTA
Dosage Form : TABLET;ORAL
Dosage Strength : 1MG
Approval Date : 2012-01-27
Application Number : 202324
RX/OTC/DISCN : RX
RLD : Yes
TE Code :
RLD : Yes
TE Code :
Brand Name : INLYTA
Dosage Form : TABLET;ORAL
Dosage Strength : 5MG
Approval Date : 2012-01-27
Application Number : 202324
RX/OTC/DISCN : RX
RLD : Yes
TE Code :
RLD :
TE Code :
Brand Name : AXITINIB
Dosage Form : TABLET;ORAL
Dosage Strength : 1MG
Approval Date :
Application Number : 210234
RX/OTC/DISCN :
RLD :
TE Code :
RLD :
TE Code :
Brand Name : AXITINIB
Dosage Form : TABLET;ORAL
Dosage Strength : 5MG
Approval Date :
Application Number : 210234
RX/OTC/DISCN :
RLD :
TE Code :
Related Excipient Companies
Dosage Form : Capsule
Grade : Not Available
Excipients by Applications
Global Sales Information
Dosage Form : Antic-calc Tablet, Film Coated
Dosage Strength : 5 mg
Price Per Pack (Euro) : 4,622.66
Published in :
Country : Norway
RX/OTC/DISCN :
Dosage Form : Antic-calc Tablet, Film Coated
Dosage Strength : 1 mg
Price Per Pack (Euro) : 928.99
Published in :
Country : Norway
RX/OTC/DISCN :
Dosage Form : Antic-calc Tablet, Film Coated
Dosage Strength : 3 mg
Price Per Pack (Euro) : 3,076.63
Published in :
Country : Norway
RX/OTC/DISCN :
Dosage Form : Antic-calc Tablet, Film Coated
Dosage Strength : 5 mg
Price Per Pack (Euro) : 4,622.66
Published in :
Country : Norway
RX/OTC/DISCN :
Dosage Form : Antic-calc Tablet, Film Coated
Dosage Strength : 7 mg
Price Per Pack (Euro) : 6,529.60
Published in :
Country : Norway
RX/OTC/DISCN :
Dosage Form : Axitinib 1Mg 56 Combined Oral Us...
Dosage Strength : 56 cpr riv 1 mg
Price Per Pack (Euro) : 1,317.03
Published in :
Country : Italy
RX/OTC/DISCN : Class H
Dosage Form : Axitinib 3Mg 56 Combined Oral Us...
Dosage Strength : 56 cpr riv 3 mg
Price Per Pack (Euro) : 3,951.11
Published in :
Country : Italy
RX/OTC/DISCN : Class H
Dosage Form : Axitinib 5Mg 56 Combined Oral Us...
Dosage Strength : 56 cpr riv 5 mg
Price Per Pack (Euro) : 6,585.15
Published in :
Country : Italy
RX/OTC/DISCN : Class H
Dosage Form : Axitinib 7Mg 56 Combined Oral Us...
Dosage Strength : 56 cpr riv 7 mg
Price Per Pack (Euro) : 9,219.22
Published in :
Country : Italy
RX/OTC/DISCN : Class H
Dosage Form : Filmtabl
Dosage Strength : 1mg
Price Per Pack (Euro) : 682.69
Published in :
Country : Switzerland
RX/OTC/DISCN : Class A
Market Place
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24 May 2023
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30 Sep 2022
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21 Sep 2022
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09 Feb 2021
Patents & EXCLUSIVITIES
Patent Expiration Date : 2035-02-03
US Patent Number : 10570202
Drug Substance Claim :
Drug Product Claim :
Application Number : 202324
Patent Use Code : U-2844
Delist Requested :
Patent Use Description :
Patent Expiration Date : 2035-02-03
Patent Expiration Date : 2025-10-29
US Patent Number : 6534524*PED
Drug Substance Claim :
Drug Product Claim :
Application Number : 202324
Patent Use Code :
Delist Requested :
Patent Use Description :
Patent Expiration Date : 2025-10-29
Patent Expiration Date : 2035-02-03
US Patent Number : 10570202
Drug Substance Claim :
Drug Product Claim :
Application Number : 202324
Patent Use Code : U-2844
Delist Requested :
Patent Use Description :
Patent Expiration Date : 2035-02-03
Patent Expiration Date : 2031-06-14
US Patent Number : 8791140*PED
Drug Substance Claim :
Drug Product Claim :
Application Number : 202324
Patent Use Code :
Delist Requested :
Patent Use Description :
Patent Expiration Date : 2031-06-14
Patent Expiration Date : 2037-01-12
US Patent Number : 10869924
Drug Substance Claim :
Drug Product Claim :
Application Number : 202324
Patent Use Code : U-3044
Delist Requested :
Patent Use Description :
Patent Expiration Date : 2037-01-12
Patent Expiration Date : 2031-06-14
US Patent Number : 8791140*PED
Drug Substance Claim :
Drug Product Claim :
Application Number : 202324
Patent Use Code :
Delist Requested :
Patent Use Description :
Patent Expiration Date : 2031-06-14
Patent Expiration Date : 2037-01-12
US Patent Number : 10869924
Drug Substance Claim :
Drug Product Claim :
Application Number : 202324
Patent Use Code : U-3044
Delist Requested :
Patent Use Description :
Patent Expiration Date : 2037-01-12
Patent Expiration Date : 2037-07-12
US Patent Number : 10869924*PED
Drug Substance Claim :
Drug Product Claim :
Application Number : 202324
Patent Use Code :
Delist Requested :
Patent Use Description :
Patent Expiration Date : 2037-07-12
Patent Expiration Date : 2030-12-14
US Patent Number : 8791140
Drug Substance Claim : Y
Drug Product Claim :
Application Number : 202324
Patent Use Code :
Delist Requested :
Patent Use Description :
Patent Expiration Date : 2030-12-14
Patent Expiration Date : 2037-07-12
US Patent Number : 10869924*PED
Drug Substance Claim :
Drug Product Claim :
Application Number : 202324
Patent Use Code :
Delist Requested :
Patent Use Description :
Patent Expiration Date : 2037-07-12
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