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Chemistry

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Also known as: 603148-36-3, Ttp488, Azeliragon [inn], Azeliragon free base, Pf-04494700, Azeliragon [usan]
Molecular Formula
C32H38ClN3O2
Molecular Weight
532.1  g/mol
InChI Key
KJNNWYBAOPXVJY-UHFFFAOYSA-N
FDA UNII
LPU25F15UQ

Azeliragon
Azeliragon has been used in trials studying the treatment of Alzheimer's Disease.
1 2D Structure

Azeliragon

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3-[4-[2-butyl-1-[4-(4-chlorophenoxy)phenyl]imidazol-4-yl]phenoxy]-N,N-diethylpropan-1-amine
2.1.2 InChI
InChI=1S/C32H38ClN3O2/c1-4-7-9-32-34-31(25-10-16-28(17-11-25)37-23-8-22-35(5-2)6-3)24-36(32)27-14-20-30(21-15-27)38-29-18-12-26(33)13-19-29/h10-21,24H,4-9,22-23H2,1-3H3
2.1.3 InChI Key
KJNNWYBAOPXVJY-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCCCC1=NC(=CN1C2=CC=C(C=C2)OC3=CC=C(C=C3)Cl)C4=CC=C(C=C4)OCCCN(CC)CC
2.2 Other Identifiers
2.2.1 UNII
LPU25F15UQ
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1-propanamine, 3-(4-(2-butyl-1-(4-(4-chlorophenoxy)phenyl)-1h-imidazol-4-yl)phenoxy)-n,n-diethyl-

2. 3-(4-(2-butyl-1-(4-(4-chlorophenoxy)phenyl)-1h-imidazol-4-yl)phenoxy)-n,n-diethyl-1-propanamine

3. Ttp488

2.3.2 Depositor-Supplied Synonyms

1. 603148-36-3

2. Ttp488

3. Azeliragon [inn]

4. Azeliragon Free Base

5. Pf-04494700

6. Azeliragon [usan]

7. Ttp-488

8. Lpu25f15uq

9. Ttp488;pf-04494700

10. 3-(4-(2-butyl-1-(4-(4-chlorophenoxy)phenyl)-1h-imidazol-4-yl)phenoxy)-n,n-diethylpropan-1-amine

11. Ttp448

12. 603148-36-3 (free Base)

13. 1-propanamine, 3-(4-(2-butyl-1-(4-(4-chlorophenoxy)phenyl)-1h-imidazol-4-yl)phenoxy)-n,n-diethyl-

14. 3-[4-[2-butyl-1-[4-(4-chlorophenoxy)phenyl]imidazol-4-yl]phenoxy]-n,n-diethylpropan-1-amine

15. Unii-lpu25f15uq

16. 3-(4-(2-butyl-1-(4-(4-chlorophenoxy)phenyl)-1h-imidazol-4-yl)phenoxy)-n,n-diethyl-1-propanamine

17. 3-[4-[2-butyl-1-[4-(4-chlorophenoxy)phenyl]-1h-imidazol-4-yl]phenoxy]-n,n-diethyl-1-propanamine

18. Azeliragon (usan/inn)

19. Azeliragon [usan:inn]

20. Azeliragon [who-dd]

21. Gtpl8317

22. Schembl1142599

23. Chembl3989929

24. Dtxsid601117468

25. Amy17088

26. Bcp16862

27. Ex-a1834

28. Bdbm50249580

29. Mfcd11977600

30. S6415

31. Zinc38336973

32. Akos026750516

33. Azeliragonpf-04494700,ttp488

34. Cs-5117

35. Db12689

36. Sb19818

37. Ac-35831

38. As-49837

39. Hy-50682

40. D11147

41. N11192

42. Q27074825

43. 1-propanamine,3-[4-[2-butyl-1-[4-(4-chlorophenoxy)phenyl]-1h-imidazol-4-yl]phenoxy]-n,n-diethyl-

44. 1421852-66-5

2.4 Create Date
2006-10-26
3 Chemical and Physical Properties
Molecular Weight 532.1 g/mol
Molecular Formula C32H38ClN3O2
XLogP38.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count14
Exact Mass531.2652552 g/mol
Monoisotopic Mass531.2652552 g/mol
Topological Polar Surface Area39.5 Ų
Heavy Atom Count38
Formal Charge0
Complexity626
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Azeliragon Manufacturers

A Azeliragon manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Azeliragon, including repackagers and relabelers. The FDA regulates Azeliragon manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Azeliragon API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Azeliragon Suppliers

A Azeliragon supplier is an individual or a company that provides Azeliragon active pharmaceutical ingredient (API) or Azeliragon finished formulations upon request. The Azeliragon suppliers may include Azeliragon API manufacturers, exporters, distributors and traders.

Azeliragon GMP

Azeliragon Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Azeliragon GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Azeliragon GMP manufacturer or Azeliragon GMP API supplier for your needs.

Azeliragon CoA

A Azeliragon CoA (Certificate of Analysis) is a formal document that attests to Azeliragon's compliance with Azeliragon specifications and serves as a tool for batch-level quality control.

Azeliragon CoA mostly includes findings from lab analyses of a specific batch. For each Azeliragon CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Azeliragon may be tested according to a variety of international standards, such as European Pharmacopoeia (Azeliragon EP), Azeliragon JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Azeliragon USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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