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ACTIVE PHARMA INGREDIENTS

57 API Suppliers, 17 USDMF, 10 JDMF, 10 EU WC, 15 KDMF, 6 NDC API, 37 Listed Suppliers, $ API Reference Price

57 API Suppliers
17 USDMF
10 JDMF
10 EU WC
15 KDMF
6 NDC API
37 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

7 Drugs in Development

7 Drugs in Development

INTERMEDIATES

33 Intermediates Suppliers

33 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

30 FDF Dossiers, 6 FDA Orange Book, 16 Europe, 4 Canada, 4 Listed Dossiers

30 FDF Dossiers
6 FDA Orange Book
16 Europe
4 Canada
4 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

TABLET;ORAL - EQ 40MG MEDOXOMIL, TABLET;ORAL - EQ 80MG MEDOXOMIL, TABLET;ORAL - EQ 40MG MEDOXOMIL;12.5MG, TABLET;ORAL - EQ 40MG MEDOXOMIL;25MG

drugProductComposition
TABLET;ORAL - EQ 40MG MEDOXOMIL
TABLET;ORAL - EQ 80MG MEDOXOMIL
TABLET;ORAL - EQ 40MG MEDOXOMIL;12.5MG
TABLET;ORAL - EQ 40MG MEDOXOMIL;25MG

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc, 13 SPI Pharma, 3 DKSH, 1 Jai Radhe Sales, 3 Faran Shimi Pharmaceutical, 7 Gangwal Healthcare, 1 Pfanstiehl, 1 ACG Worldwide, 1 Aeon Procare, 5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 1 BASF, 10 Corel Pharma Chem, 3 DFE Pharma, 5 Gangwal Chemicals, 5 Ideal Cures Pvt Ltd, 2 Ingredion Pharma Solutions, 17 Kerry, 3 Kima Chemical, 6 Lonza Capsugel, 10 Microlex e.U, 1 Novo Excipients, 1 Pharmatrans-Sanaq, 3 Pluviaendo, 3 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 1 Qualicaps, 13 Roquette, 7 Seppic, 5 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Shijiazhuang Huaxu Pharmaceutical, 10 Sigachi Industries, 2 The Dow Chemical Company, 3 Vasa Pharmachem

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44 Coating Systems & Additives, 41 Fillers, Diluents & Binders, 23 Direct Compression, 21 Controlled & Modified Release, 15 Disintegrants & Superdisintegrants, 12 Thickeners and Stabilizers, 12 Lubricants & Glidants, 12 Chewable & Orodispersible Aids, 12 Co-Processed Excipients, 12 Taste Masking, 12 Granulation, 7 Film Formers & Plasticizers, 5 Empty Capsules, 5 Coloring Agents, 4 Parenteral, 4 Vegetarian Capsules, 4 API Stability Enhancers, 3 Rheology Modifiers, 2 Emulsifying Agents, 1 Solubilizers

DIGITAL CONTENT

3 DATA COMPILATION #PharmaFlow, 15 NEWS #PharmaBuzz

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3 DATA COMPILATION #PharmaFlow
15 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 10 Finished Drug Prices, 8 Annual Reports

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1 US Medicaid Prescriptions
10 Finished Drug Prices
8 Annual Reports

MARKET PLACE

16 APIs

marketPlace
16 APIs

PATENTS & EXCLUSIVITIES

16 US Patents, 2 Health Canada Patents

patents
16 US Patents
2 Health Canada Patents

REF. STANDARDS & IMPURITIES

10 Others

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10 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 1,436

MARKET PLACE

API

FDF

33INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

7DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

36,008,755

Annual Reports (USD Million)

4,921

Finished Drug Prices

149 RELATED EXCIPIENT COMPANIES

251EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 863031-24-7, Azilsartan (medoxomil monopotassium), Azilsartan kamedoxomil, Azilsartan medoxomil monopotassium, Bcp11249, Sb19561

Molecular Formula

C₃₀H₂₃KN₄O₈

Molecular Weight

606.6 g/mol

InChI Key

IHWFKDWIUSZLCJ-UHFFFAOYSA-M

1 2D Structure

Azilsartan

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

potassium;(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-3-[[4-[2-(5-oxo-1-oxa-4-aza-2-azanidacyclopent-3-en-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate

2.1.2 InChI

InChI=1S/C30H24N4O8.K/c1-3-38-28-31-23-10-6-9-22(27(35)39-16-24-17(2)40-30(37)41-24)25(23)34(28)15-18-11-13-19(14-12-18)20-7-4-5-8-21(20)26-32-29(36)42-33-26;/h4-14H,3,15-16H2,1-2H3,(H,32,33,36);/q;+1/p-1

2.1.3 InChI Key

IHWFKDWIUSZLCJ-UHFFFAOYSA-M

2.1.4 Canonical SMILES

CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NC(=O)O[N-]5)C(=O)OCC6=C(OC(=O)O6)C.[K+]

2.2 Synonyms

2.2.1 Depositor-Supplied Synonyms

1. 863031-24-7

2. Azilsartan (medoxomil Monopotassium)

3. Azilsartan Kamedoxomil

4. Azilsartan Medoxomil Monopotassium

5. Bcp11249

6. Sb19561

7. Hy-17458

8. Potassium;(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-3-[[4-[2-(5-oxo-1-oxa-4-aza-2-azanidacyclopent-3-en-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate

9. Potassium 3-(4'-((2-ethoxy-7-(((5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy)carbonyl)-1h-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-yl)-5-oxo-5h-1,2,4-oxadiazol-2-ide

2.3 Create Date

2015-09-21

3 Chemical and Physical Properties

Molecular Formula	C₃₀H₂₃KN₄O₈
Molecular Weight	606.6 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	10
Exact Mass	606.11529519 g/mol
Monoisotopic Mass	606.11529519 g/mol
Topological Polar Surface Area	129 Å²
Heavy Atom Count	43
Formal Charge	0
Complexity	1110
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 FDA Pharmacological Classification

4.1.1 Pharmacological Classes

Angiotensin 2 Type 1 Receptor Antagonists [MoA]; Decreased Blood Pressure [PE]; Angiotensin 2 Receptor Blocker [EPC]

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API Reference Price

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