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Chemistry

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Also known as: 863031-24-7, Azilsartan (medoxomil monopotassium), Azilsartan kamedoxomil, Azilsartan medoxomil monopotassium, Bcp11249, Sb19561
Molecular Formula
C30H23KN4O8
Molecular Weight
606.6  g/mol
InChI Key
IHWFKDWIUSZLCJ-UHFFFAOYSA-M

Azilsartan
1 2D Structure

Azilsartan

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
potassium;(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-3-[[4-[2-(5-oxo-1-oxa-4-aza-2-azanidacyclopent-3-en-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate
2.1.2 InChI
InChI=1S/C30H24N4O8.K/c1-3-38-28-31-23-10-6-9-22(27(35)39-16-24-17(2)40-30(37)41-24)25(23)34(28)15-18-11-13-19(14-12-18)20-7-4-5-8-21(20)26-32-29(36)42-33-26;/h4-14H,3,15-16H2,1-2H3,(H,32,33,36);/q;+1/p-1
2.1.3 InChI Key
IHWFKDWIUSZLCJ-UHFFFAOYSA-M
2.1.4 Canonical SMILES
CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NC(=O)O[N-]5)C(=O)OCC6=C(OC(=O)O6)C.[K+]
2.2 Synonyms
2.2.1 Depositor-Supplied Synonyms

1. 863031-24-7

2. Azilsartan (medoxomil Monopotassium)

3. Azilsartan Kamedoxomil

4. Azilsartan Medoxomil Monopotassium

5. Bcp11249

6. Sb19561

7. Hy-17458

8. Potassium;(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-3-[[4-[2-(5-oxo-1-oxa-4-aza-2-azanidacyclopent-3-en-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate

9. Potassium 3-(4'-((2-ethoxy-7-(((5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy)carbonyl)-1h-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-yl)-5-oxo-5h-1,2,4-oxadiazol-2-ide

2.3 Create Date
2015-09-21
3 Chemical and Physical Properties
Molecular Weight 606.6 g/mol
Molecular Formula C30H23KN4O8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count10
Rotatable Bond Count10
Exact Mass606.11529519 g/mol
Monoisotopic Mass606.11529519 g/mol
Topological Polar Surface Area129 Ų
Heavy Atom Count43
Formal Charge0
Complexity1110
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 FDA Pharmacological Classification
4.1.1 Pharmacological Classes
Angiotensin 2 Type 1 Receptor Antagonists [MoA]; Decreased Blood Pressure [PE]; Angiotensin 2 Receptor Blocker [EPC]

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C-24,","city":"HYDERABAD. AP","supplier":"MSN LABORATORIES","supplierCountry":"INDIA","foreign_port":"BOGOTA","customer":"LAFRANCOL S.A.S","customerCountry":"COLOMBIA","quantity":"20.00","actualQuantity":"20","unit":"KGS","unitRateFc":"2600","totalValueFC":"51452.2","currency":"USD","unitRateINR":214760.01349999997,"date":"18-Jun-2024","totalValueINR":"4295200.27","totalValueInUsd":"51452.2","indian_port":"Hyderabad Air","hs_no":"29331999","bill_no":"1749339","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"COLOMBIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"MSN HOUSE, PLOT NO. C-24,, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1719340200,"product":"AZILSARTAN KAMEDOXOMIL","address":"MSN HOUSE, PLOT NO. C-24,","city":"HYDERABAD. AP","supplier":"MSN LABORATORIES","supplierCountry":"INDIA","foreign_port":"BUCHAREST","customer":"GEDEON RICHTER","customerCountry":"ROMANIA","quantity":"105.00","actualQuantity":"105","unit":"KGS","unitRateFc":"4250","totalValueFC":"441548.9","currency":"USD","unitRateINR":351050,"date":"26-Jun-2024","totalValueINR":"36860250","totalValueInUsd":"441548.9","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"1965810","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ROMANIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"MSN HOUSE, PLOT NO. C-24,, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725993000,"product":"AZILSARTAN","address":"2 FLR.PRESTIGE PLAZA","city":"AKOTA BARODA","supplier":"AMI LIFESCIENCES PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"OSAKA","customer":"TO THE ORDER OF,","customerCountry":"JAPAN","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"2500","totalValueFC":"7358.2","currency":"USD","unitRateINR":205541.53333333333,"date":"11-Sep-2024","totalValueINR":"616624.6","totalValueInUsd":"7358.2","indian_port":"Ahmedabad Air","hs_no":"29332990","bill_no":"3912926","productDescription":"API","marketType":"REGULATED MARKET","country":"JAPAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Ahmedabad Air","supplierAddress":"2 FLR.PRESTIGE PLAZA, AKOTA BARODA","customerAddress":""}]
07-Jan-2021
11-Sep-2024
KGS
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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INTERMEDIATES SUPPLIERS

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01

2024 ACI Convention
Not Confirmed
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  • fda
  • EDQM
  • WHO-GMP

Virtual BoothShandong Loncom is an R&D-focused manufacturer of Anti-cancer APIs.

CAS Number : 147403-65-4

End Use API : Azilsartan

About The Company : Established in May 2012, Shandong Loncom Pharmaceutical operates as a fully owned subsidiary of Shandong Bestcomm Pharmaceutical Co., Ltd. Situated in the Qihe ...

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02

Almelo

India
2024 ACI Convention
Not Confirmed
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Almelo

India
2024 ACI Convention
Not Confirmed
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CAS Number : CAS-147403-65-4

End Use API : Azilsartan

About The Company : Almelo are the industry leaders in manufacturing advanced intermediates, Active Pharmaceutical Ingredients (APIs) and specialty fine chemicals. With a diverse p...

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03

Almelo

India
2024 ACI Convention
Not Confirmed
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Almelo

India
2024 ACI Convention
Not Confirmed
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CAS Number : CAS-139481-44-0

End Use API : Azilsartan

About The Company : Almelo are the industry leaders in manufacturing advanced intermediates, Active Pharmaceutical Ingredients (APIs) and specialty fine chemicals. With a diverse p...

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04

Almelo

India
2024 ACI Convention
Not Confirmed
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Almelo

India
2024 ACI Convention
Not Confirmed
arrow

CAS Number : CAS-147403-03-0

End Use API : Azilsartan

About The Company : Almelo are the industry leaders in manufacturing advanced intermediates, Active Pharmaceutical Ingredients (APIs) and specialty fine chemicals. With a diverse p...

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05

Almelo

India
2024 ACI Convention
Not Confirmed
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Almelo

India
2024 ACI Convention
Not Confirmed
arrow

CAS Number : CAS-147403-52-9

End Use API : Azilsartan

About The Company : Almelo are the industry leaders in manufacturing advanced intermediates, Active Pharmaceutical Ingredients (APIs) and specialty fine chemicals. With a diverse p...

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06

2024 ACI Convention
Not Confirmed
arrow
2024 ACI Convention
Not Confirmed
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CAS Number : 147403-65-4

End Use API : Azilsartan

About The Company : CTX is one of the youngest and fastest-growing Indian API and Intermediate manufacturing companies doing business in over 70 countries. In these five years, all...

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07

2024 ACI Convention
Not Confirmed
arrow
2024 ACI Convention
Not Confirmed
arrow

CAS Number : 147403-52-9

End Use API : Azilsartan

About The Company : CTX is one of the youngest and fastest-growing Indian API and Intermediate manufacturing companies doing business in over 70 countries. In these five years, all...

blank

08

2024 ACI Convention
Not Confirmed
arrow
2024 ACI Convention
Not Confirmed
arrow

CAS Number : 147403-03-0

End Use API : Azilsartan

About The Company : CTX is one of the youngest and fastest-growing Indian API and Intermediate manufacturing companies doing business in over 70 countries. In these five years, all...

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09

2024 ACI Convention
Not Confirmed
arrow
2024 ACI Convention
Not Confirmed
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CAS Number : 139481-44-0

End Use API : Azilsartan

About The Company : Established in 2011 and situated in Hangzhou, Zhejiang, China, Hangzhou Longshine Bio-Tech CO., Ltd is dedicated to providing services for pharmaceutical and ch...

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10

2024 ACI Convention
Not Confirmed
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2024 ACI Convention
Not Confirmed
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CAS Number : 147403-52-9

End Use API : Azilsartan

About The Company : Established in 2011 and situated in Hangzhou, Zhejiang, China, Hangzhou Longshine Bio-Tech CO., Ltd is dedicated to providing services for pharmaceutical and ch...

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - TABLET;ORAL - EQ 40MG MEDOXOMIL

USFDA APPLICATION NUMBER - 200796

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DOSAGE - TABLET;ORAL - EQ 80MG MEDOXOMIL

USFDA APPLICATION NUMBER - 200796

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DOSAGE - TABLET;ORAL - EQ 40MG MEDOXOMIL;12.5...DOSAGE - TABLET;ORAL - EQ 40MG MEDOXOMIL;12.5MG

USFDA APPLICATION NUMBER - 202331

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DOSAGE - TABLET;ORAL - EQ 40MG MEDOXOMIL;25MG

USFDA APPLICATION NUMBER - 202331

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Patents & EXCLUSIVITIES

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US Patents

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01

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World Vaccine Congress
Not Confirmed

AZURITY

U.S.A
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World Vaccine Congress
Not Confirmed

AZILSARTAN KAMEDOXOMIL; CHLORTHALIDONE

US Patent Number : 7157584

Drug Substance Claim : Y

Drug Product Claim :

Application Number : 202331

Patent Use Code :

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2025-05-22

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02

arrow
World Vaccine Congress
Not Confirmed

AZURITY

U.S.A
arrow
World Vaccine Congress
Not Confirmed

AZILSARTAN KAMEDOXOMIL; CHLORTHALIDONE

US Patent Number : 7572920

Drug Substance Claim :

Drug Product Claim : Y

Application Number : 202331

Patent Use Code : U-3

Delist Requested :

Patent Use Description : TREATMENT OF HYPERTENS...

Patent Expiration Date : 2025-01-07

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03

arrow
World Vaccine Congress
Not Confirmed

AZURITY

U.S.A
arrow
World Vaccine Congress
Not Confirmed

AZILSARTAN KAMEDOXOMIL; CHLORTHALIDONE

US Patent Number : 7157584

Drug Substance Claim : Y

Drug Product Claim :

Application Number : 202331

Patent Use Code :

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2025-05-22

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04

arrow
World Vaccine Congress
Not Confirmed

AZURITY

U.S.A
arrow
World Vaccine Congress
Not Confirmed

AZILSARTAN KAMEDOXOMIL; CHLORTHALIDONE

US Patent Number : 7572920

Drug Substance Claim :

Drug Product Claim : Y

Application Number : 202331

Patent Use Code : U-3

Delist Requested :

Patent Use Description : TREATMENT OF HYPERTENS...

Patent Expiration Date : 2025-01-07

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05

arrow
World Vaccine Congress
Not Confirmed

AZURITY

U.S.A
arrow
World Vaccine Congress
Not Confirmed

AZILSARTAN KAMEDOXOMIL; CHLORTHALIDONE

US Patent Number : 9169238

Drug Substance Claim :

Drug Product Claim : Y

Application Number : 202331

Patent Use Code :

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2030-02-04

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06

arrow
World Vaccine Congress
Not Confirmed

AZURITY

U.S.A
arrow
World Vaccine Congress
Not Confirmed

AZILSARTAN KAMEDOXOMIL

US Patent Number : 7572920

Drug Substance Claim :

Drug Product Claim : Y

Application Number : 200796

Patent Use Code : U-3

Delist Requested :

Patent Use Description : TREATMENT OF HYPERTENS...

Patent Expiration Date : 2025-01-07

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07

arrow
World Vaccine Congress
Not Confirmed

AZURITY

U.S.A
arrow
World Vaccine Congress
Not Confirmed

AZILSARTAN KAMEDOXOMIL; CHLORTHALIDONE

US Patent Number : 9169238

Drug Substance Claim :

Drug Product Claim : Y

Application Number : 202331

Patent Use Code :

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2030-02-04

blank

08

arrow
World Vaccine Congress
Not Confirmed

AZURITY

U.S.A
arrow
World Vaccine Congress
Not Confirmed

AZILSARTAN KAMEDOXOMIL

US Patent Number : 7572920

Drug Substance Claim :

Drug Product Claim : Y

Application Number : 200796

Patent Use Code : U-3

Delist Requested :

Patent Use Description : TREATMENT OF HYPERTENS...

Patent Expiration Date : 2025-01-07

blank

09

arrow
World Vaccine Congress
Not Confirmed

AZURITY

U.S.A
arrow
World Vaccine Congress
Not Confirmed

AZILSARTAN KAMEDOXOMIL

US Patent Number : 7157584

Drug Substance Claim : Y

Drug Product Claim :

Application Number : 200796

Patent Use Code :

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2025-05-22

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10

arrow
World Vaccine Congress
Not Confirmed

AZURITY

U.S.A
arrow
World Vaccine Congress
Not Confirmed

AZILSARTAN KAMEDOXOMIL; CHLORTHALIDONE

US Patent Number : 9066936

Drug Substance Claim :

Drug Product Claim : Y

Application Number : 202331

Patent Use Code :

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2028-03-26

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