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Polfa Tarchomin is a leading Polish pharmaceutical company with 200 year tradition in manufacture and sale of pharmaceutical products.

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ACTIVE PHARMA INGREDIENTS

35 API Suppliers, 22 USDMF, 5 CEP/COS, 2 JDMF, 15 NDC API, 1 VMF, 13 Listed Suppliers, $ API Reference Price

35 API Suppliers
22 USDMF
5 CEP/COS
2 JDMF
15 NDC API
1 VMF
13 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

66 FDF Dossiers, 39 FDA Orange Book, 4 Europe, 17 Canada, 2 South Africa, 4 Listed Dossiers

66 FDF Dossiers
39 FDA Orange Book
4 Europe
17 Canada
2 South Africa
4 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

OINTMENT;TOPICAL - 400 UNITS/GM;1%;EQ 3.5MG BASE/GM;5,000 UNITS/GM **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, OINTMENT;OPHTHALMIC - EQ 400 UNITS/GM;EQ 3.5MG BASE/GM;EQ 10,000 UNITS/GM

drugProductComposition
OINTMENT;TOPICAL - 400 UNITS/GM;1%;EQ 3.5MG BASE/GM;5,000 UNITS/GM **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
OINTMENT;OPHTHALMIC - EQ 400 UNITS/GM;EQ 3.5MG BASE/GM;EQ 10,000 UNITS/GM

RELATED EXCIPIENT COMPANIES

1 SPI Pharma, 1 DKSH, 3 Nanjing Well Pharmaceutical, 1 Pfanstiehl, 10 Actylis, 11 BASF, 1 Finar, 5 Gangwal Chemicals, 4 Kerry, 2 Microlex e.U, 1 Nanjing Bold Chemical, 2 Nippon Fine Chemical, 1 Pluviaendo, 5 Roquette, 7 Seppic

relatedExcipients
1 SPI Pharma
1 DKSH
3 Nanjing Well Pharmaceutical
1 Pfanstiehl
10 Actylis
11 BASF
1 Finar
5 Gangwal Chemicals
4 Kerry
2 Microlex e.U
1 Nanjing Bold Chemical
2 Nippon Fine Chemical
1 Pluviaendo
5 Roquette
7 Seppic

EXCIPIENTS BY APPLICATIONS

18 Topical, 15 Solubilizers, 12 Parenteral, 9 Coating Systems & Additives, 8 Thickeners and Stabilizers, 8 Film Formers & Plasticizers, 6 Emulsifying Agents, 5 Co-Processed Excipients, 5 Direct Compression, 4 Surfactant & Foaming Agents, 3 Lubricants & Glidants, 3 Fillers, Diluents & Binders, 3 Granulation, 2 Taste Masking, 2 Controlled & Modified Release, 1 Rheology Modifiers, 1 API Stability Enhancers

excipientsByApplications
18 Topical
15 Solubilizers
12 Parenteral
9 Coating Systems & Additives
8 Thickeners and Stabilizers
8 Film Formers & Plasticizers
6 Emulsifying Agents
5 Co-Processed Excipients
5 Direct Compression
4 Surfactant & Foaming Agents
3 Lubricants & Glidants
3 Fillers, Diluents & Binders
3 Granulation
2 Taste Masking
2 Controlled & Modified Release
1 Rheology Modifiers
1 API Stability Enhancers

DIGITAL CONTENT

11 NEWS #PharmaBuzz

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11 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

5 Finished Drug Prices

globalSalesInformation
5 Finished Drug Prices

MARKET PLACE

21 APIs, 1 FDF Dossiers

marketPlace
21 APIs
1 FDF Dossiers

REF. STANDARDS & IMPURITIES

1 EDQM , 1 USP , 1 Others

otherSolutions
1 EDQM
1 USP
1 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 486

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

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Data Compilation #PharmaFlow

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GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

55 RELATED EXCIPIENT COMPANIES

105EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Bacitracin a2a, Baciguent, Fortracin, Bacitracinum, Parentracin, Penitracin

Molecular Formula

C₆₆H₁₀₃N₁₇O₁₆S

Molecular Weight

1422.7 g/mol

InChI Key

CLKOFPXJLQSYAH-ABRJDSQDSA-N

FDA UNII

DDA3RRX0P7

Bacitracin is a combination of at least 9 bacitracins. 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.

1 2D Structure

Bacitracin Zinc

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(4R)-4-[[(2S)-2-[[(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2S,3S)-1-[[(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2S)-butan-2-yl]-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclopentacos-21-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid

2.1.2 InChI

InChI=1S/C66H103N17O16S/c1-9-35(6)52(69)66-81-48(32-100-66)63(97)76-43(26-34(4)5)59(93)74-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)75-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-72-39)77-60(94)44(27-38-18-13-12-14-19-38)80-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)73-56(40)90/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,72)(H,71,89)(H,73,90)(H,74,93)(H,75,98)(H,76,97)(H,77,94)(H,78,96)(H,79,95)(H,80,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88)/t35-,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48-,52-,53-,54-/m0/s1

2.1.3 InChI Key

CLKOFPXJLQSYAH-ABRJDSQDSA-N

2.1.4 Canonical SMILES

CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCCCCC(C(=O)NC(C(=O)N1)CCCN)NC(=O)C(C(C)CC)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C2CSC(=N2)C(C(C)CC)N)CC(=O)N)CC(=O)O)CC3=CN=CN3)CC4=CC=CC=C4

2.1.5 Isomeric SMILES

CC[C@H](C)[C@H]1C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)NCCCC[C@@H](C(=O)N[C@@H](C(=O)N1)CCCN)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]2CSC(=N2)[C@H]([C@@H](C)CC)N)CC(=O)N)CC(=O)O)CC3=CN=CN3)CC4=CC=CC=C4

2.2 Other Identifiers

2.2.1 UNII

DDA3RRX0P7

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. Bacitracin A2a

2. Baciguent

3. Fortracin

4. Bacitracinum

5. Parentracin

6. Penitracin

7. Topitracin

8. Zutracin

9. Baciim

10. Baci-rx

11. Solu-tracin 50

12. 22601-59-8

13. Chebi:35862

14. Dda3rrx0p7

15. Altracin

16. Bacitracin A1

17. E700

18. Bacitracin F, 1-(n-((2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl)carbonyl)-l-leucine)-

19. Ayfivin

20. Unii-dda3rrx0p7

21. Baciliquin

22. Bacilliquin

23. Bacitracina

24. Bacitracine

25. Mycitracin

26. Topitrasin

27. Tropitracin

28. Septa

29. Spectrocin Plus

30. Bacitek Ointment

31. Nsc-45737

32. Bacitracin Powder

33. Ak-tracin

34. Baci-jel

35. Bacitracin Complex

36. Nsc-755905

37. Baciferm 50

38. Bacitracin, Sterile

39. Einecs 245-115-9

40. Nsc 45737

41. Bacitracine [french]

42. Bacitracinum [latin]

43. Albac 50

44. Bacitracina [spanish]

45. Bactine Triple Antibiotic

46. Bacitracin(non-injectable)

47. Usaf Cb-7

48. Unii-58h6rwo52i

49. Mycitracin Plus Pain Reliever

50. 58h6rwo52i

51. Chembl1200558

52. Schembl20385900

53. Hsdb 6418

54. Bacitracin [usp:inn:ban:jan]

55. Einecs 215-786-2

56. Bdbm50458054

57. Bacitracin-neomycin-polymyxin Ointment

58. Db00626

59. Nsc 755905

60. Ai3-50147-x

61. Campho-phenique Triple Plus Pain Reliever

62. Q424319

63. Mycitracin Triple Antibiotic First Aid Ointment Maximum Strength

64. 85800-09-5

65. L-asparagine, N-(((4r)-2-((1s,2s)-1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl)carbonyl)-l-leucyl-d-.alpha.-glutamyl-l-isoleucyl-l-lysyl-d-ornithyl-l-isoleucyl-d-phenylalanyl-l-histidyl-d-.alpha.-aspartyl-, (10->4)-lactam

66. N-({(4r)-2-[(1s,2s)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazol-4-yl}carbonyl)-l-leucyl-d-alpha-glutamyl-n-[(3s,6r,9s,12r,15s,18r,21s)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2s)-butan-2-yl]-6-(carboxymethyl)-9-(1h-imidazol-4-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl]-l-isoleucinamide

2.4 Create Date

2006-10-26

3 Chemical and Physical Properties

Molecular Formula	C₆₆H₁₀₃N₁₇O₁₆S
Molecular Weight	1422.7 g/mol
XLogP3	-4.1
Hydrogen Bond Donor Count	17
Hydrogen Bond Acceptor Count	21
Rotatable Bond Count	31
Exact Mass	1421.74894144 g/mol
Monoisotopic Mass	1421.74894144 g/mol
Topological Polar Surface Area	556 Å²
Heavy Atom Count	100
Formal Charge	0
Complexity	2850
Isotope Atom Count	0
Defined Atom Stereocenter Count	15
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Baciim
Drug Label	Bacitracin for Injection, USP is a sterile antibiotic for intramuscular administration. Bacitracin is derived from cultures of Bacillus subtilis (Tracey). It is a white to pale buff, hygroscopic powder, odorless or having a slight odor. It is freely...
Active Ingredient	Bacitracin
Dosage Form	Injectable
Route	Injection
Strength	50,000 units/vial
Market Status	Prescription
Company	X Gen Pharms

2 of 2
Drug Name	Baciim
Drug Label	Bacitracin for Injection, USP is a sterile antibiotic for intramuscular administration. Bacitracin is derived from cultures of Bacillus subtilis (Tracey). It is a white to pale buff, hygroscopic powder, odorless or having a slight odor. It is freely...
Active Ingredient	Bacitracin
Dosage Form	Injectable
Route	Injection
Strength	50,000 units/vial
Market Status	Prescription
Company	X Gen Pharms

4.2 Drug Indication

Bacitracin is indicated in topical formulations for acute and chronic localized skin infections. Occasionally, it is also used intramuscularly for infantile streptococcal pneumonia and empyema. Bacitracin is also formulated as an ointment with neomycin and polymyxin B for over the counter use. A bacitracin ointment formulated with neomycin and polymyxin B along with hydrocortisone is indicated for the treatment of corticosteroid responsive dermatoses with secondary infection.

5 Pharmacology and Biochemistry

5.1 Pharmacology

Bacitracin is a mixture of polypeptides that prevent the formation of the bacterial cell wall and oxidatively cleave DNA. It has a short duration of action as it must be given every 3 to 4 hours topically. Bacitracin is nephrotoxic when given intramuscularly and may lead to renal failure.

5.2 Absorption, Distribution and Excretion

Absorption

Topical, ophthalmic, and oral formulations of bacitracin are poorly absorbed systemically. Intramuscular bacitracin is readily and completely absorbed.

Route of Elimination

Bacitracin is mainly excreted renally with 87% of and intramuscular dose being recovered in the urine after 6 hours.

Volume of Distribution

Data regarding the volume of distribution of bacitracin in humans is not readily available.

Clearance

Data regarding the clearance of bacitracin in humans has not been well studied. A study of 9 subjects in 1947 shows a renal clearance of 105-283mL/min with an average renal clearance of 159mL/min.

5.3 Metabolism/Metabolites

Data regarding the metabolism of bacitracin in humans is not readily available. Because bacitracin is a protein it is expected to be metabolized into smaller polypeptides and amino acids. However, the structure of bacitracin may afford it some protection from the action of proteases.

5.4 Biological Half-Life

Data regarding the half life of bacitracin in humans is not readily available.

5.5 Mechanism of Action

Bacitracin binds to a divalent metal ion such as Mn(II), Co(II), Ni(II), Cu(II), or Zn(II). These complexes bind C₅₅-isoprenyl pyrophosphate, preventing the hydrolysis of a lipid dolichol pyrophosphate, which finally inhibits cell wall synthesis. Bacitracin metal complexes also bind and oxidatively cleave DNA.

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01

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API Reference Price

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Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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DOSAGE - OINTMENT;TOPICAL - 400 UNITS/GM;1%;E...DOSAGE - OINTMENT;TOPICAL - 400 UNITS/GM;1%;EQ 3.5MG BASE/GM;5,000 UNITS/GM **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 50168

DOSAGE - OINTMENT;OPHTHALMIC - EQ 400 UNITS/G...DOSAGE - OINTMENT;OPHTHALMIC - EQ 400 UNITS/GM;EQ 3.5MG BASE/GM;EQ 10,000 UNITS/GM

USFDA APPLICATION NUMBER - 50417

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ABOUT THIS PAGE

Bacitracin Zinc Manufacturers

A Bacitracin Zinc manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Bacitracin Zinc, including repackagers and relabelers. The FDA regulates Bacitracin Zinc manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Bacitracin Zinc API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Bacitracin Zinc manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Bacitracin Zinc Suppliers

A Bacitracin Zinc supplier is an individual or a company that provides Bacitracin Zinc active pharmaceutical ingredient (API) or Bacitracin Zinc finished formulations upon request. The Bacitracin Zinc suppliers may include Bacitracin Zinc API manufacturers, exporters, distributors and traders.

click here to find a list of Bacitracin Zinc suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Bacitracin Zinc USDMF

A Bacitracin Zinc DMF (Drug Master File) is a document detailing the whole manufacturing process of Bacitracin Zinc active pharmaceutical ingredient (API) in detail. Different forms of Bacitracin Zinc DMFs exist exist since differing nations have different regulations, such as Bacitracin Zinc USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Bacitracin Zinc DMF submitted to regulatory agencies in the US is known as a USDMF. Bacitracin Zinc USDMF includes data on Bacitracin Zinc's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Bacitracin Zinc USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Bacitracin Zinc suppliers with USDMF on PharmaCompass.

Bacitracin Zinc JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Bacitracin Zinc Drug Master File in Japan (Bacitracin Zinc JDMF) empowers Bacitracin Zinc API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Bacitracin Zinc JDMF during the approval evaluation for pharmaceutical products. At the time of Bacitracin Zinc JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Bacitracin Zinc suppliers with JDMF on PharmaCompass.

Bacitracin Zinc CEP

A Bacitracin Zinc CEP of the European Pharmacopoeia monograph is often referred to as a Bacitracin Zinc Certificate of Suitability (COS). The purpose of a Bacitracin Zinc CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Bacitracin Zinc EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Bacitracin Zinc to their clients by showing that a Bacitracin Zinc CEP has been issued for it. The manufacturer submits a Bacitracin Zinc CEP (COS) as part of the market authorization procedure, and it takes on the role of a Bacitracin Zinc CEP holder for the record. Additionally, the data presented in the Bacitracin Zinc CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Bacitracin Zinc DMF.

A Bacitracin Zinc CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Bacitracin Zinc CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Bacitracin Zinc suppliers with CEP (COS) on PharmaCompass.

Bacitracin Zinc NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Bacitracin Zinc as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Bacitracin Zinc API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Bacitracin Zinc as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Bacitracin Zinc and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Bacitracin Zinc NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Bacitracin Zinc suppliers with NDC on PharmaCompass.

Bacitracin Zinc GMP

Bacitracin Zinc Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Bacitracin Zinc GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Bacitracin Zinc GMP manufacturer or Bacitracin Zinc GMP API supplier for your needs.

Bacitracin Zinc CoA

A Bacitracin Zinc CoA (Certificate of Analysis) is a formal document that attests to Bacitracin Zinc's compliance with Bacitracin Zinc specifications and serves as a tool for batch-level quality control.

Bacitracin Zinc CoA mostly includes findings from lab analyses of a specific batch. For each Bacitracin Zinc CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Bacitracin Zinc may be tested according to a variety of international standards, such as European Pharmacopoeia (Bacitracin Zinc EP), Bacitracin Zinc JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Bacitracin Zinc USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

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ACTIVE PHARMA INGREDIENTS

35 API Suppliers

22 USDMF

5 CEP/COS

2 JDMF

15 NDC API

1 VMF

13 Listed Suppliers

$ API Reference Price

FINISHED DOSAGE FORMULATIONS

66 FDF Dossiers

39 FDA Orange Book

4 Europe

17 Canada

2 South Africa

4 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

OINTMENT;TOPICAL - 400 UNITS/GM;1%;EQ 3.5MG BASE/GM;5,000 UNITS/GM **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

OINTMENT;OPHTHALMIC - EQ 400 UNITS/GM;EQ 3.5MG BASE/GM;EQ 10,000 UNITS/GM

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5 Roquette

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EXCIPIENTS BY APPLICATIONS

18 Topical

15 Solubilizers

12 Parenteral

9 Coating Systems & Additives

8 Thickeners and Stabilizers

8 Film Formers & Plasticizers

6 Emulsifying Agents

5 Co-Processed Excipients

5 Direct Compression

4 Surfactant & Foaming Agents

3 Lubricants & Glidants

3 Fillers, Diluents & Binders

3 Granulation

2 Taste Masking

2 Controlled & Modified Release

1 Rheology Modifiers

1 API Stability Enhancers

DIGITAL CONTENT

11 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

5 Finished Drug Prices

MARKET PLACE

21 APIs

1 FDF Dossiers

REF. STANDARDS & IMPURITIES

1 EDQM

1 USP

1 Others

ACTIVE PHARMA INGREDIENTS

API REF. PRICE (USD/KG)

$ 486

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DIGITAL CONTENT

OINTMENT;TOPICAL - 400 UNITS/GM;1%;EQ 3.5MG BASE/GM;5,000 UNITS/GM Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons