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Chemistry

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Also known as: 21967-41-9, Baicalein 7-o-glucuronide, 7-d-glucuronic acid-5,6-dihydroxyflavone, Mfcd00134418, Chebi:2981, Chembl485818
Molecular Formula
C21H18O11
Molecular Weight
446.4  g/mol
InChI Key
IKIIZLYTISPENI-ZFORQUDYSA-N
FDA UNII
347Q89U4M5

Baicalin
baicalin is a natural product found in Scutellaria amoena, Thalictrum baicalense, and other organisms with data available.
1 2D Structure

Baicalin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S,3S,4S,5R,6S)-6-(5,6-dihydroxy-4-oxo-2-phenylchromen-7-yl)oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
2.1.2 InChI
InChI=1S/C21H18O11/c22-9-6-10(8-4-2-1-3-5-8)30-11-7-12(14(23)15(24)13(9)11)31-21-18(27)16(25)17(26)19(32-21)20(28)29/h1-7,16-19,21,23-27H,(H,28,29)/t16-,17-,18+,19-,21+/m0/s1
2.1.3 InChI Key
IKIIZLYTISPENI-ZFORQUDYSA-N
2.1.4 Canonical SMILES
C1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)OC4C(C(C(C(O4)C(=O)O)O)O)O)O)O
2.1.5 Isomeric SMILES
C1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O)O)O
2.2 Other Identifiers
2.2.1 UNII
347Q89U4M5
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 7-d-glucuronic Acid-5,6-dihydroxy-flavone

2. 7-d-glucuronic Acid-5,6-dihydroxyflavone

2.3.2 Depositor-Supplied Synonyms

1. 21967-41-9

2. Baicalein 7-o-glucuronide

3. 7-d-glucuronic Acid-5,6-dihydroxyflavone

4. Mfcd00134418

5. Chebi:2981

6. Chembl485818

7. 31564-28-0

8. 5,6-dihydroxy-4-oxo-2-phenyl-4h-chromen-7-yl Beta-d-glucopyranosiduronic Acid

9. Baicalein 7-o-.beta.-d-glucuronide

10. 347q89u4m5

11. (2s,3s,4s,5r,6s)-6-((5,6-dihydroxy-4-oxo-2-phenyl-4h-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2h-pyran-2-carboxylic Acid

12. 5,6,7-trihydroxyflavone 7-o-beta-d-glucuronide

13. (2s,3s,4s,5r,6s)-6-(5,6-dihydroxy-4-oxo-2-phenylchromen-7-yl)oxy-3,4,5-trihydroxyoxane-2-carboxylic Acid

14. (2s,3s,4s,5r,6s)-6-[(5,6-dihydroxy-4-oxo-2-phenyl-4h-chromen-7-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic Acid

15. 5,6-dihydroxy-4-oxo-2-phenyl-4h-1-benzopyran-7-yl

16. A-d-glucopyranosiduronic Acid

17. Baicalein 7-glucuronide

18. Baicalein-7-o-glucuronide

19. 5,6-dihydroxy-4-oxo-2-phenyl-4h-1-benzopyran-7-yl Beta-d-glucopyranosiduronic Acid

20. Baikalin

21. Baicaloside

22. Baicalin,(s)

23. (2s,3s,4s,5r,6s)-6-(5,6-dihydroxy-4-oxo-2-phenyl-4h-chromen-7-yloxy)-3,4,5-trihydroxytetrahydro-2h-pyran-2-carboxylic Acid

24. 0xe

25. Baicalin, 95%

26. Baicalin [inci]

27. Baicalin [vandf]

28. Baicalein-7-d-glucuronide

29. Baicalin [who-dd]

30. Schembl285082

31. Baicalein 7-beta-d-glucuronide

32. Baicalein 7-o-b-d-glucuronide

33. Baikal Skullcap Extract Baicalin

34. Unii-347q89u4m5

35. Tjn-151

36. Dtxsid701346569

37. Baicalin, >=99.0% (hplc)

38. Hy-n0197

39. Zinc3943903

40. Bdbm50242173

41. Akos007930529

42. Akos015955933

43. Baicalin 1000 Microg/ml In Methanol

44. Ac-7990

45. Am84780

46. Ccg-214128

47. Cs-5302

48. Beta-d-glucopyranosiduronic Acid, 5,6-dihydroxy-4-oxo-2-phenyl-4h-1-benzopyran-7-yl

49. Baicalein 7-beta-d-glucopyranosiduronate

50. Ncgc00386028-03

51. (2s,3s,4s,5r,6s)-6-(5,6-dihydroxy-4-oxo-2-phenyl-chromen-7-yl)oxy-3,4, 5-trihydroxy-oxane-2-carboxylic Acid

52. (2s,3s,4s,5r,6s)-6-(5,6-dihydroxy-4-oxo-2-phenyl-chromen-7-yl)oxy-3,4,5-trihydroxy-oxane-2-carboxylic Acid

53. (2s,3s,4s,5r,6s)-6-(5,6-dihydroxy-4-oxo-2-phenyl-chromen-7-yl)oxy-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic Acid

54. As-13226

55. Baicalein 7-o-glucuronide [usp-rs]

56. 967b419

57. A815791

58. J-013512

59. Q-100275

60. Q2879368

61. Brd-k49962337-001-01-1

62. Baicalin, European Pharmacopoeia (ep) Reference Standard

63. 5,6,7-trihydroxyflavone-7-o-.beta.-d-glucopyranosideuronic Acid

64. 5,6-dihydroxy-4-oxo-2-phenyl-4h-chromen-7-yl Ss-d-glucopyranosiduronic Acid

65. (2s,3s,4s,5r,6r)-6-(5,6-dihydroxy-4-oxo-2-phenyl-chromen-7-yl)oxy-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic Acid

66. (2s,3s,4s,5r,6s)-6-(5,6-dihydroxy-4-oxo-2-phenyl-4h-chromen-7-yloxy)-3,4,5-trihydroxy-tetrahydro-2h-pyran-2-carboxylic Acid

67. .beta.-d-glucopyranosiduronic Acid, 5,6-dihydroxy-4-oxo-2-phenyl-4h-1-benzopyran-7-yl

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 446.4 g/mol
Molecular Formula C21H18O11
XLogP31.1
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count11
Rotatable Bond Count4
Exact Mass446.08491139 g/mol
Monoisotopic Mass446.08491139 g/mol
Topological Polar Surface Area183 Ų
Heavy Atom Count32
Formal Charge0
Complexity748
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Infective Agents

Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (See all compounds classified as Anti-Infective Agents.)


Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


Enzyme Inhibitors

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)


Anti-Asthmatic Agents

Drugs that are used to treat asthma. (See all compounds classified as Anti-Asthmatic Agents.)


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Baicalin manufacturers, exporters & distributors 1

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PharmaCompass also assists you with knowing the Baicalin API Price utilized in the formulation of products. Baicalin API Price is not always fixed or binding as the Baicalin Price is obtained through a variety of data sources. The Baicalin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Baicalin

Synonyms

21967-41-9, Baicalein 7-o-glucuronide, 7-d-glucuronic acid-5,6-dihydroxyflavone, Mfcd00134418, Chebi:2981, Chembl485818

Cas Number

21967-41-9

Unique Ingredient Identifier (UNII)

347Q89U4M5

About Baicalin

baicalin is a natural product found in Scutellaria amoena, Thalictrum baicalense, and other organisms with data available.

Baicalin Manufacturers

A Baicalin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Baicalin, including repackagers and relabelers. The FDA regulates Baicalin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Baicalin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Baicalin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Baicalin Suppliers

A Baicalin supplier is an individual or a company that provides Baicalin active pharmaceutical ingredient (API) or Baicalin finished formulations upon request. The Baicalin suppliers may include Baicalin API manufacturers, exporters, distributors and traders.

click here to find a list of Baicalin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Baicalin GMP

Baicalin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Baicalin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Baicalin GMP manufacturer or Baicalin GMP API supplier for your needs.

Baicalin CoA

A Baicalin CoA (Certificate of Analysis) is a formal document that attests to Baicalin's compliance with Baicalin specifications and serves as a tool for batch-level quality control.

Baicalin CoA mostly includes findings from lab analyses of a specific batch. For each Baicalin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Baicalin may be tested according to a variety of international standards, such as European Pharmacopoeia (Baicalin EP), Baicalin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Baicalin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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