Find Hydrocortisone manufacturers, exporters & distributors on PharmaCompass

Balneol-hc

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

49 API Suppliers, 29 USDMF, 14 CEP/COS, 6 JDMF, 5 EU WC, 10 KDMF, 41 NDC API, 1 VMF, 21 Listed Suppliers, $ API Reference Price

49 API Suppliers
29 USDMF
14 CEP/COS
6 JDMF
5 EU WC
10 KDMF
41 NDC API
1 VMF
21 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

21 Drugs in Development

21 Drugs in Development

FINISHED DOSAGE FORMULATIONS

381 FDF Dossiers, 227 FDA Orange Book, 83 Europe, 13 Canada, 6 Australia, 27 South Africa, 25 Listed Dossiers

381 FDF Dossiers
227 FDA Orange Book
83 Europe
13 Canada
6 Australia
27 South Africa
25 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

SUSPENSION/DROPS;OTIC - EQ 0.2% BASE;1%, CREAM;TOPICAL - 5%;1%, OINTMENT;TOPICAL - 400 UNITS/GM;1%;EQ 3.5MG BASE/GM;5,000 UNITS/GM **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, CREAM;TOPICAL - 1%, TABLET;ORAL - 10MG, TABLET;ORAL - 20MG, TABLET;ORAL - 5MG

drugProductComposition
SUSPENSION/DROPS;OTIC - EQ 0.2% BASE;1%
CREAM;TOPICAL - 5%;1%
OINTMENT;TOPICAL - 400 UNITS/GM;1%;EQ 3.5MG BASE/GM;5,000 UNITS/GM **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
CREAM;TOPICAL - 1%
TABLET;ORAL - 10MG
TABLET;ORAL - 20MG
TABLET;ORAL - 5MG

RELATED EXCIPIENT COMPANIES

5 Rochem International Inc, 8 SPI Pharma, 2 Seqens, 16 DKSH, 2 Jai Radhe Sales, 2 Nippon Fine Chemical, 1 Pharm-RX Chemical, 13 Gangwal Healthcare, 21 Nanjing Well Pharmaceutical, 5 Pfanstiehl, 22 Actylis, 1 Aeon Procare, 7 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 42 BASF, 3 BioSpectra, 1 Clariant, 15 Corel Pharma Chem, 7 DFE Pharma, 6 Finar, 16 Gangwal Chemicals, 2 Hayashibara, 3 Ideal Cures Pvt Ltd, 4 Ingredion Pharma Solutions, 31 Kerry, 9 Lubrizol Life Science Health, 17 Microlex e.U, 3 Nanjing Bold Chemical, 2 Nomisma Healthcare, 1 Novo Excipients, 2 Pharmatrans-Sanaq, 8 Pluviaendo, 4 Prachin Chemical, 33 Roquette, 21 Seppic, 2 Shandong Focus Biotechnology Co., Ltd, 5 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Shijiazhuang Huaxu Pharmaceutical, 11 Sigachi Industries, 2 Valens Pharmachem, 5 Vasa Pharmachem, 1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

87 Topical, 75 Fillers, Diluents & Binders, 56 Solubilizers, 56 Thickeners and Stabilizers, 45 Parenteral, 40 Direct Compression, 30 Coating Systems & Additives, 29 Lubricants & Glidants, 29 Disintegrants & Superdisintegrants, 28 Granulation, 27 Emulsifying Agents, 24 Controlled & Modified Release, 20 Surfactant & Foaming Agents, 20 Co-Processed Excipients, 19 Film Formers & Plasticizers, 18 Taste Masking, 11 Chewable & Orodispersible Aids, 8 Rheology Modifiers, 5 API Stability Enhancers, 2 Coloring Agents, 1 Soft Gelatin

DIGITAL CONTENT

4 DATA COMPILATION #PharmaFlow, 46 NEWS #PharmaBuzz

media
4 DATA COMPILATION #PharmaFlow
46 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

8 US Medicaid Prescriptions, 91 Finished Drug Prices, 1 Annual Reports

globalSalesInformation
8 US Medicaid Prescriptions
91 Finished Drug Prices
1 Annual Reports

MARKET PLACE

27 APIs, 16 FDF Dossiers

marketPlace
27 APIs
16 FDF Dossiers

PATENTS & EXCLUSIVITIES

12 US Patents

patents
12 US Patents

REF. STANDARDS & IMPURITIES

4 EDQM , 4 USP , 3 JP , 5 Others

otherSolutions
4 EDQM
4 USP
3 JP
5 Others

ANALYTICAL

2 BioAnalytical Methods, 4 Analytical Methods

otherMethods
2 BioAnalytical Methods
4 Analytical Methods

EuroAPI Hydrocortisone

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 592

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

381

FDF Dossiers

227

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

21DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

3,419,784

Annual Reports (USD Million)

Finished Drug Prices

362 RELATED EXCIPIENT COMPANIES

630EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: Cortisol, 50-23-7, Acticort, Cetacort, Cortef, Hydrasson

Molecular Formula

C₂₁H₃₀O₅

Molecular Weight

362.5 g/mol

InChI Key

JYGXADMDTFJGBT-VWUMJDOOSA-N

FDA UNII

WI4X0X7BPJ

The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.

Hydrocortisone is a Corticosteroid. The mechanism of action of hydrocortisone is as a Corticosteroid Hormone Receptor Agonist.

1 2D Structure

Hydrocortisone

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one

2.1.2 InChI

InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

2.1.3 InChI Key

JYGXADMDTFJGBT-VWUMJDOOSA-N

2.1.4 Canonical SMILES

CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O

2.1.5 Isomeric SMILES

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O

2.2 Other Identifiers

2.2.1 UNII

WI4X0X7BPJ

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 11 Epicortisol

2. 11-epicortisol

3. Cortef

4. Cortifair

5. Cortisol

6. Cortril

7. Epicortisol

8. Hydrocortisone, (11 Alpha)-isomer

9. Hydrocortisone, (9 Beta,10 Alpha,11 Alpha)-isomer

10. Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-

2.3.2 Depositor-Supplied Synonyms

1. Cortisol

2. 50-23-7

3. Acticort

4. Cetacort

5. Cortef

6. Hydrasson

7. Hydrocortisyl

8. Hydrocortone

9. Cobadex

10. Hytone

11. Cortenema

12. Cortril

13. Dermacort

14. Proctocort

15. Hycort

16. Signef

17. 17-hydroxycorticosterone

18. Optef

19. Kendall's Compound F

20. Cort-dome

21. Cortanal

22. Corticreme

23. Cortifan

24. Cortiment

25. Cortispray

26. Cortonema

27. Dermolate

28. Efcorbin

29. Efcortelan

30. Eldecort

31. Ficortril

32. Genacort

33. Hycortol

34. Hycortole

35. Penecort

36. Permicort

37. Tarcortin

38. Traumaide

39. Alacort

40. Cleiton

41. Epicort

42. Dihydrocostisone

43. Hytone Lotion

44. Hidro-colisona

45. Hydro-adreson

46. Scheroson F

47. Incortin-h

48. Reichstein's Substance M

49. Ala-scalp

50. Domolene-hc

51. Epiderm H

52. Esiderm H

53. Otosone-f

54. Polcort H

55. Aeroseb-hc

56. Cortolotion

57. Cortoxide

58. Cremesone

59. Eldercort

60. Heb-cort

61. Maintasone

62. Nutracort

63. Delacort

64. Dioderm

65. Mildison

66. Rectoid

67. Synacort

68. Anflam

69. Hydrocorticosterone

70. Hydroxycortisone

71. H-cort

72. Hydro-colisona

73. Cortisol Alcohol

74. Incortin-hydrogen

75. Ala-cort

76. Barseb Hc

77. Dermocortal

78. Flexicort

79. Texacort

80. Timocort

81. Evacort

82. Komed Hc

83. Hydrocortisone Base

84. Lacticare-hc

85. Texacort Lotion 25

86. Anti-inflammatory Hormone

87. Hydrocortisone Alcohol

88. Algicirtis

89. Aquacort

90. Colocort

91. Cortesal

92. Cortisolonum

93. Hidalone

94. Hytisone

95. Kyypakkaus

96. Lactisona

97. Lubricort

98. Meusicort

99. Milliderm

100. Sanatison

101. Schericur

102. Sigmacort

103. Stiefcorcil

104. Amberin

105. Cutisol

106. Dermil

107. Glycort

108. Uniderm

109. Foille Insetti

110. Gyno-cortisone

111. Balneol-hc

112. Transderma H

113. Basan-corti

114. Clear Aid

115. Cremicort-h

116. Dome-cort

117. Stie-cort

118. Beta-hc

119. Neosporin-h Ear

120. Remederm Hc

121. Aquanil Hc

122. Cortisporin Otico

123. Derm-aid

124. Heb Cort

125. Nogenic Hc

126. Scalpicin Capilar

127. Systral Hydrocort

128. Prevex Hc

129. Cortisporin

130. Efcortelin

131. Fiocortril

132. Hidrocortisona

133. Hydrocortisone Free Alcohol

134. Hydrocortisonum

135. Proctofoam

136. Alphaderm

137. Hydracort

138. Medicort

139. Otocort

140. Zenoxone

141. Drotic

142. Vytone

143. 11beta-hydroxycortisone

144. Nystaform-hc

145. Aeroseb Hc

146. Caldecort Spray

147. Anusol Hc

148. Pediotic Suspension

149. Vosol Hc

150. Idrocortisone

151. 17alpha-hydroxycorticosterone

152. Hydrocortal

153. Hydroskin

154. Otalgine

155. Otobiotic

156. Plenadren

157. Protocort

158. Hysone

159. Racet

160. Ef Corlin

161. 11beta-hydrocortisone

162. Compound F

163. Lacticare Hc

164. Compound F (kendall)

165. 11-beta-hydrocortisone

166. 11-beta-hydroxycortisone

167. Hydrocortisone (cortisol)

168. Chronocort

169. Hydrocort

170. Preparation H Hydrocortisone Cream

171. Neo-cort-dome

172. 11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione

173. Otic-neo-cort-dome

174. 11beta,17,21-trihydroxypregn-4-ene-3,20-dione

175. Nsc 10483

176. Hc

177. [3h]cortisol

178. Nsc-10483

179. (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione

180. Prestwick_265

181. (8s,9s,10r,11s,13s,14s,17r)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1h-cyclopenta[a]phenanthren-3-one

182. 4-pregnene-11beta,17alpha,21-triol-3,20-dione

183. Chebi:17650

184. 11beta,17alpha,21-trihydroxypregn-4-ene-3,20-dione

185. Nsc10483

186. 11.beta.-hydrocortisone

187. Dermaspray

188. Wi4x0x7bpj

189. 11beta,17,21-trihydroxyprogesterone

190. 11.beta.-hydroxycortisone

191. Ophthocort

192. Terra-cortril

193. Mls000069609

194. 17.alpha.-hydroxycorticosterone

195. Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11.beta.)-

196. Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-

197. 4-pregnen-11beta,17alpha,21-triol-3,20-dione

198. Idrocortisone [dcit]

199. Genacort (lotion)

200. Anucort

201. Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11b)-

202. Prepcort

203. Smr000059022

204. Dsstox_cid_714

205. Hydrocortisonum [inn-latin]

206. Proctozone Hc

207. Scalp-cort

208. Hidrocortisona [inn-spanish]

209. Rectasol-hc

210. Anucort-hc

211. Hydro-rx

212. Dsstox_rid_75753

213. Dsstox_gsid_20714

214. (8s,9s,10r,11s,13s,14s,17r)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-3(2h)-one

215. Hc (hydrocortisone)

216. 11.beta.,17,21-trihydroxypregn-4-ene-3,20-dione

217. Corhydron

218. (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione

219. Duocort

220. Hydrocortisone In Absorbase

221. Proctosol-hc

222. Hc #1

223. Hc #4

224. Acticort (tn)

225. Colocort (tn)

226. (1s,2r,10s,11s,14r,15s,17s)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one

227. Smr000653523

228. Cortef (tn)

229. Hytone (tn)

230. Ccris 5854

231. Component Of Otalgine

232. Anusol Hc (tn)

233. Component Of Lubricort

234. Cor-oticin

235. Hsdb 3339

236. Einecs 200-020-1

237. Unii-wi4x0x7bpj

238. Mfcd00011654

239. Component Of Neo-cort-dome

240. Cortizol

241. Efmody

242. Ai3-25006

243. 3h-cortisol

244. 11beta-cortisol

245. Cas-50-23-7

246. 11-hydrocortisone

247. Plenadren (tn)

248. Ncgc00022848-06

249. 11b-hydrocortisone

250. Hydrocortisone [usp:inn:ban:jan]

251. Drotic (salt/mix)

252. 11b-hydroxycortisone

253. Otocort (salt/mix)

254. Pregn-4-ene-3,20-dione, 11beta,17,21-trihydroxy-

255. Otalgine (salt/mix)

256. Hydrocortisone, 98%

257. 11,17,21-trihydroxypregn-4-ene-3,20-dione

258. Alkindi Sprinkle

259. Alphaderm (salt/mix)

260. Hydrocortisone, Topical

261. Otobiotic (salt/mix)

262. 4p6x

263. Cort-quin (salt/mix)

264. Cortisporin (salt/mix)

265. Vosol Hc (salt/mix)

266. 11a-hydroxycorticosterone

267. 17a-hydroxycorticosterone

268. Opera_id_1292

269. Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11-beta)-

270. Prestwick0_000447

271. Prestwick1_000447

272. Prestwick2_000447

273. Prestwick3_000447

274. Epitope Id:174851

275. Upcmld-dp133

276. Ec 200-020-1

277. H 4001

278. Hydrocortisone [ii]

279. Hydrocortisone [mi]

280. Schembl4148

281. Neo-cort-dome (salt/mix)

282. Hydrocortisone [inn]

283. Hydrocortisone [jan]

284. Lopac0_000594

285. 11alpha-hydroxycorticosterone

286. Bspbio_000494

287. Hydrocortisone [hsdb]

288. Mls001148103

289. Mls002207135

290. Mls002222189

291. Mls002548868

292. Hydrocortisone [vandf]

293. Spbio_002433

294. Hydrocortisone [mart.]

295. Bpbio1_000544

296. Chembl389621

297. Gtpl2868

298. Hydrocortisone [usp-rs]

299. Hydrocortisone [who-dd]

300. Hydrocortisone [who-ip]

301. Pediotic Suspension (salt/mix)

302. Dtxsid7020714

303. Upcmld-dp133:001

304. Bdbm13775

305. Otic-neo-cort-dome (salt/mix)

306. 2v95

307. Hydrocortisone (jp17/usp/inn)

308. Hms1569i16

309. Hms2090m04

310. Hms2096i16

311. Hms2230b18

312. Hms2235f17

313. Hms3259c05

314. Hms3261h10

315. Hms3713i16

316. Hydrocortisone, >=98% (hplc)

317. Vioform-hydrocortisone (salt/mix)

318. 11b,17,21-trihydroxyprogesterone

319. Hydrocortisone [green Book]

320. Bcp09054

321. Hy-n0583

322. Hydrocortisone [orange Book]

323. Tox21_110883

324. Tox21_200815

325. Tox21_500594

326. Hydrocortisone [ep Monograph]

327. Lmst02030001

328. S1696

329. Zinc13540519

330. Hydrocortisone [usp Monograph]

331. Akos001582651

332. Hydrocortisonum [who-ip Latin]

333. Oticair Component Hydrocortisone

334. Otocort Component Hydrocortisone

335. Tox21_110883_1

336. Ccg-204683

337. Db00741

338. Lp00594

339. Nc00456

340. Sdccgsbi-0050576.p003

341. 11.beta.,17,21-trihydroxyprogesterone

342. Cipro Hc Component Hydrocortisone

343. Orlex Hc Component Hydrocortisone

344. Otobione Component Hydrocortisone

345. Pediotic Component Hydrocortisone

346. Pyocidin Component Hydrocortisone

347. Smp1_000156

348. Vosol Hc Component Hydrocortisone

349. Alphaderm Component Hydrocortisone

350. Ncgc00022848-07

351. Ncgc00022848-09

352. Ncgc00022848-10

353. Ncgc00022848-11

354. Ncgc00022848-12

355. Ncgc00022848-13

356. Ncgc00022848-14

357. Ncgc00022848-15

358. Ncgc00022848-17

359. Ncgc00022848-26

360. Ncgc00258369-01

361. Ncgc00261279-01

362. Otobiotic Component Hydrocortisone

363. (1s,10s,11s,15s,17s,2r,14r)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyl Tetracyclo[8.7.0.0<2,7>.0<11,15>]heptadec-6-en-5-one

364. (8s,9s,10r,11s,13s,14s,17r)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3h-cyclopenta[a]phenanthren-3-one

365. Ac-12902

366. As-11651

367. Bp-20390

368. Hydrocortisone 100 Microg/ml In Methanol

369. Hydrocortisone Component Of Oticair

370. Hydrocortisone Component Of Otocort

371. Nci60_000118

372. Acetasol Hc Component Hydrocortisone

373. Calmurid Hc Component Hydrocortisone

374. Hydrocortisone Component Of Otobione

375. Hydrocortisone Component Of Pediotic

376. Hydrocortisone Component Of Pyocidin

377. 4-pregnene-11alpha,21-triol 3,20-dione

378. Hydrocortisone Component Of Alphaderm

379. Hydrocortisone Component Of Cipro Hc

380. Hydrocortisone Component Of Orlex Hc

381. Hydrocortisone Component Of Otobiotic

382. Hydrocortisone Component Of Vosol Hc

383. B1951

384. Eu-0100594

385. Prednisolone Impurity A [ep Impurity]

386. 4-pregnene-11b,17a,21-triol-3,20-dione

387. Hydrocortisone 100 Microg/ml In Acetonitrile

388. Hydrocortisone Component Of Acetasol Hc

389. Hydrocortisone Component Of Calmurid Hc

390. 50h237

391. C00735

392. D00088

393. U 1851

394. Hydrocortisone, Meets Usp Testing Specifications

395. Pregn-4-ene-3, 11.beta.,17,21-trihydroxy-

396. 11?,17?,21-trihydroxypregn-4-ene-3,20-dione

397. A929789

398. Hydrocortisone, Vetranal(tm), Analytical Standard

399. Q190875

400. Sr-01000000139

401. Q-201211

402. Sr-01000000139-3

403. Brd-k93568044-001-03-1

404. Brd-k93568044-001-11-4

405. Brd-k93568044-001-32-0

406. Hydrocortisone Acetate Impurity A [ep Impurity]

407. Hydrocortisone, Bioreagent, Suitable For Cell Culture

408. 4-pregnen-11.beta.,17.alpha.,21-triol-3,20-dione

409. 4-pregnene-11.beta.,17.alpha.,21-triol-3,20-dione

410. Pregn-4-ene-3,20-dione, 11.beta.,17,21-trihydroxy-

411. Z2786051549

412. (11beta)-11,17,21-trihydroxy-pregn-4-ene-3,20-dione

413. 11.beta.,17.alpha.,21-trihydroxy-4-pregnene-3,20-dione

414. 11.beta.,17.alpha.,21-trihydroxypregn-4-ene-3,20-dione

415. B48448a1-24ba-47ca-8d9e-43e5bc949386

416. Hydrocortisone, British Pharmacopoeia (bp) Assay Standard

417. Pregn-4-ene-3, 11,17,21-trihydroxy-, (11.beta.)-

418. 11,17,21-trihydroxypregn-4-ene-3,20-dione, (11.beta.)-

419. Hydrocortisone Sodium Succinate Impurity A [ep Impurity]

420. Hydrocortisone, European Pharmacopoeia (ep) Reference Standard

421. Hydrocortisone Hydrogen Succinate Impurity A [ep Impurity]

422. Hydrocortisone, United States Pharmacopeia (usp) Reference Standard

423. Hydrocortisone-water Soluble, Bioreagent, Suitable For Cell Culture

424. Hydrocortisone, Gamma-irradiated, Powder, Bioxtra, Suitable For Cell Culture

425. 4-(6-chloro-4-oxoquinazolin-3(4h)-yl)-n-(3-methoxyphenyl)piperidine-1-carboxamide

426. Cortisol Solution, 1.0 Mg/ml In Methanol, Ampule Of 1 Ml, Certified Reference Material

427. Hydrocortisone For Peak Identification, European Pharmacopoeia (ep) Reference Standard

428. Hydrocortisone Solution, 50 Mum, Sterile-filtered, Bioxtra, Suitable For Cell Culture

429. Hydrocortisone, Pharmaceutical Secondary Standard; Certified Reference Material

430. (10r,13s,17r)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1h-cyclopenta[a]phenanthren-3-one

2.3.3 Other Synonyms

1. Efficort

2. Retef

3. Hydrocortisone Aceponate

4. Cortef Fluid

5. Hydrocortisone Cypionate

6. Hidroaltesona

7. Hydrocortone Phosphate

8. Hydrocortisone Phosphate

9. Hydrocortisone Sodium Phosphate

10. Aacicortisol

11. Hydrocortisone Hydrogen Succinate

12. Hydrocortisone Hemisuccinate Hydrate

13. Hydrocortisone Hemisuccinate

14. Hydrocortisone 21-hemisuccinate

2.4 Create Date

2004-09-16

3 Chemical and Physical Properties

Molecular Formula	C₂₁H₃₀O₅
Molecular Weight	362.5 g/mol
XLogP3	1.6
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	362.20932405 g/mol
Monoisotopic Mass	362.20932405 g/mol
Topological Polar Surface Area	94.8 Å²
Heavy Atom Count	26
Formal Charge	0
Complexity	684
Isotope Atom Count	0
Defined Atom Stereocenter Count	7
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Information

1 of 36
Drug Name	Acetasol hc
PubMed Health	Acetic Acid/Hydrocortisone (Into the ear)
Drug Classes	Anti-Infective/Anti-Inflammatory Combination
Active Ingredient	Acetic acid, glacial; hydrocortisone
Dosage Form	Solution/drops
Route	Otic
Strength	1%; 2%
Market Status	Prescription
Company	Actavis Mid Atlantic

2 of 36
Drug Name	Ala-cort
PubMed Health	Hydrocortisone
Drug Classes	Anti-Inflammatory, Corticosteroid, Intermediate, Corticosteroid, Weak, Endocrine-Metabolic Agent, Gastrointestinal Agent, Hemorrhoidal Anti-Inflammatory, Hydrocortisone, Immune Suppressant
Active Ingredient	Hydrocortisone
Dosage Form	Cream
Route	Topical
Strength	1%
Market Status	Prescription
Company	Crown Labs

3 of 36
Drug Name	Ala-scalp
PubMed Health	Hydrocortisone (On the skin)
Drug Classes	Corticosteroid, Intermediate, Corticosteroid, Weak
Active Ingredient	Hydrocortisone
Dosage Form	Lotion
Route	Topical
Strength	2%
Market Status	Prescription
Company	Crown Labs

4 of 36
Drug Name	Anusol hc
PubMed Health	Hydrocortisone (By mouth)
Drug Classes	Anti-Inflammatory, Endocrine-Metabolic Agent, Immune Suppressant
Active Ingredient	Hydrocortisone
Dosage Form	Cream
Route	Topical
Strength	2.5%
Market Status	Prescription
Company	Salix Pharms

5 of 36
Drug Name	Colocort
PubMed Health	Hydrocortisone Enema (Rectal)
Drug Classes	Anti-Inflammatory, Gastrointestinal Agent
Drug Label	Hydrocortisone is a white to practically white, odorless, crystalline powder, very slightly soluble in water. It has the chemical name Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-,(11)- and the following structural formula:Colocort is a convenien...
Active Ingredient	Hydrocortisone
Dosage Form	Enema
Route	Rectal
Strength	100mg/60ml
Market Status	Prescription
Company	Paddock

6 of 36
Drug Name	Cortef
PubMed Health	Hydrocortisone (Rectal)
Drug Classes	Anti-Inflammatory, Hemorrhoidal Anti-Inflammatory
Drug Label	CORTEF Tablets contain hydrocortisone which is a glucocorticoid. Glucocorticoids are adrenocortical steroids, both naturally occurring and synthetic, which are readily absorbed from the gastrointestinal tract. Hydrocortisone USP is white to practical...
Active Ingredient	Hydrocortisone
Dosage Form	Tablet
Route	Oral
Strength	5mg; 10mg; 20mg
Market Status	Prescription
Company	Pharmacia And Upjohn

7 of 36
Drug Name	Cortenema
PubMed Health	Neomycin, Polymyxin B, and Hydrocortisone
Drug Classes	Adrenal Glucocorticoid, Aminoglycoside/Corticosteroid Combination, Anti-Infective/Anti-Inflammatory Combination, Neomycin
Drug Label	Hydrocortisone is a white to practically white, odorless, crystalline powder, very slightly soluble in water. It has the chemical name Pregn-4-ene-3,20-dione,11,17,21-trihydroxy,(11)-and the following structural formula: CORTENEMA is a convenient...
Active Ingredient	Hydrocortisone
Dosage Form	Enema
Route	Rectal
Strength	100mg/60ml
Market Status	Prescription
Company	Ani Pharms

8 of 36
Drug Name	Cortifoam
PubMed Health	Hydrocortisone
Drug Classes	Anti-Inflammatory, Corticosteroid, Intermediate, Corticosteroid, Weak, Endocrine-Metabolic Agent, Gastrointestinal Agent, Hemorrhoidal Anti-Inflammatory, Hydrocortisone, Immune Suppressant
Active Ingredient	Hydrocortisone acetate
Dosage Form	Aerosol, metered
Route	Rectal
Strength	10%
Market Status	Prescription
Company	Meda Pharms

9 of 36
Drug Name	Cortisporin
PubMed Health	Hydrocortisone
Drug Classes	Anti-Inflammatory, Corticosteroid, Intermediate, Corticosteroid, Weak, Endocrine-Metabolic Agent, Gastrointestinal Agent, Hemorrhoidal Anti-Inflammatory, Hydrocortisone, Immune Suppressant
Active Ingredient	Hydrocortisone acetate; polymyxin b sulfate; Hydrocortisone; Bacitracin zinc; hydrocortisone; neomycin sulfate
Dosage Form	Solution/drops; Suspension/drops; Ointment; Cream
Route	Topical; Otic
Strength	400 units/gm; 10,000 units/gm; 0.5%; 10,000 units/ml; 1%; eq 3.5mg base/ml; eq 3.5mg base/gm; 5,000 units/gm
Market Status	Prescription
Company	Monarch Pharms; Citron Pharma

10 of 36
Drug Name	Hydrocortisone
Active Ingredient	Hydrocortisone
Dosage Form	Ointment; Enema; Tablet; Cream; Lotion
Route	Rectal; Oral; Topical
Strength	1%; 5mg; 10mg; 2.5%; 100mg/60ml; 20mg
Market Status	Prescription
Company	Vintage Pharms; Amedra Pharms; Taro; Fougera; Lyne; Fougera Pharms; Teva Pharms; Actavis Mid Atlantic; Vintage; Perrigo New York

11 of 36
Drug Name	Hydrocortisone and acetic acid
Drug Label	Topical corticosteroids constitute a class of primarily synthetic steroids used as anti-inflammatory and antipruritic agents. Texacort Topical Solution contains hydrocortisone as the active corticosteroid, having the chemical formula of Pregn-4-ene-3...
Active Ingredient	Acetic acid, glacial; hydrocortisone
Dosage Form	Solution/drops
Route	Otic
Strength	1%; 2%
Market Status	Prescription
Company	Taro; Vintage

12 of 36
Drug Name	Hydrocortisone in absorbase
Active Ingredient	Hydrocortisone
Dosage Form	Ointment
Route	Topical
Strength	1%
Market Status	Prescription
Company	Carolina Medcl

13 of 36
Drug Name	Hydro-rx
PubMed Health	Acetic Acid/Hydrocortisone (Into the ear)
Drug Classes	Anti-Infective/Anti-Inflammatory Combination
Drug Label	Glucocorticoids are adrenocortical steroids, both naturally occurring and synthetic, which are readily absorbed from the gastrointestinal tract.Hydrocortisone is a white to practically white, odorless, crystalline powder, very slightly soluble in wat...
Active Ingredient	Hydrocortisone
Dosage Form	Powder
Route	For rx compounding
Strength	100%
Market Status	Prescription
Company	X Gen Pharms

14 of 36
Drug Name	Nutracort
Active Ingredient	Hydrocortisone
Dosage Form	Lotion
Route	Topical
Strength	2.5%
Market Status	Prescription
Company	Dow Pharm

15 of 36
Drug Name	Stie-cort
Active Ingredient	Hydrocortisone
Dosage Form	Lotion
Route	Topical
Strength	2.5%
Market Status	Prescription
Company	Perrigo

16 of 36
Drug Name	Synacort
Active Ingredient	Hydrocortisone
Dosage Form	Cream
Route	Topical
Strength	1%; 2.5%
Market Status	Prescription
Company	Medicis

17 of 36
Drug Name	Texacort
Active Ingredient	Hydrocortisone
Dosage Form	Solution
Route	Topical
Strength	2.5%
Market Status	Prescription
Company	Mission Pharma

18 of 36
Drug Name	Vosol hc
Active Ingredient	Acetic acid, glacial; hydrocortisone
Dosage Form	Solution/drops
Route	Otic
Strength	1%; 2%
Market Status	Prescription
Company	Hi Tech Pharma

19 of 36
Drug Name	Acetasol hc
PubMed Health	Acetic Acid/Hydrocortisone (Into the ear)
Drug Classes	Anti-Infective/Anti-Inflammatory Combination
Active Ingredient	Acetic acid, glacial; hydrocortisone
Dosage Form	Solution/drops
Route	Otic
Strength	1%; 2%
Market Status	Prescription
Company	Actavis Mid Atlantic

20 of 36
Drug Name	Ala-cort
PubMed Health	Hydrocortisone
Drug Classes	Anti-Inflammatory, Corticosteroid, Intermediate, Corticosteroid, Weak, Endocrine-Metabolic Agent, Gastrointestinal Agent, Hemorrhoidal Anti-Inflammatory, Hydrocortisone, Immune Suppressant
Active Ingredient	Hydrocortisone
Dosage Form	Cream
Route	Topical
Strength	1%
Market Status	Prescription
Company	Crown Labs

21 of 36
Drug Name	Ala-scalp
PubMed Health	Hydrocortisone (On the skin)
Drug Classes	Corticosteroid, Intermediate, Corticosteroid, Weak
Active Ingredient	Hydrocortisone
Dosage Form	Lotion
Route	Topical
Strength	2%
Market Status	Prescription
Company	Crown Labs

22 of 36
Drug Name	Anusol hc
PubMed Health	Hydrocortisone (By mouth)
Drug Classes	Anti-Inflammatory, Endocrine-Metabolic Agent, Immune Suppressant
Active Ingredient	Hydrocortisone
Dosage Form	Cream
Route	Topical
Strength	2.5%
Market Status	Prescription
Company	Salix Pharms

23 of 36
Drug Name	Colocort
PubMed Health	Hydrocortisone Enema (Rectal)
Drug Classes	Anti-Inflammatory, Gastrointestinal Agent
Drug Label	Hydrocortisone is a white to practically white, odorless, crystalline powder, very slightly soluble in water. It has the chemical name Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-,(11)- and the following structural formula:Colocort is a convenien...
Active Ingredient	Hydrocortisone
Dosage Form	Enema
Route	Rectal
Strength	100mg/60ml
Market Status	Prescription
Company	Paddock

24 of 36
Drug Name	Cortef
PubMed Health	Hydrocortisone (Rectal)
Drug Classes	Anti-Inflammatory, Hemorrhoidal Anti-Inflammatory
Drug Label	CORTEF Tablets contain hydrocortisone which is a glucocorticoid. Glucocorticoids are adrenocortical steroids, both naturally occurring and synthetic, which are readily absorbed from the gastrointestinal tract. Hydrocortisone USP is white to practical...
Active Ingredient	Hydrocortisone
Dosage Form	Tablet
Route	Oral
Strength	5mg; 10mg; 20mg
Market Status	Prescription
Company	Pharmacia And Upjohn

25 of 36
Drug Name	Cortenema
PubMed Health	Neomycin, Polymyxin B, and Hydrocortisone
Drug Classes	Adrenal Glucocorticoid, Aminoglycoside/Corticosteroid Combination, Anti-Infective/Anti-Inflammatory Combination, Neomycin
Drug Label	Hydrocortisone is a white to practically white, odorless, crystalline powder, very slightly soluble in water. It has the chemical name Pregn-4-ene-3,20-dione,11,17,21-trihydroxy,(11)-and the following structural formula: CORTENEMA is a convenient...
Active Ingredient	Hydrocortisone
Dosage Form	Enema
Route	Rectal
Strength	100mg/60ml
Market Status	Prescription
Company	Ani Pharms

26 of 36
Drug Name	Cortifoam
PubMed Health	Hydrocortisone
Drug Classes	Anti-Inflammatory, Corticosteroid, Intermediate, Corticosteroid, Weak, Endocrine-Metabolic Agent, Gastrointestinal Agent, Hemorrhoidal Anti-Inflammatory, Hydrocortisone, Immune Suppressant
Active Ingredient	Hydrocortisone acetate
Dosage Form	Aerosol, metered
Route	Rectal
Strength	10%
Market Status	Prescription
Company	Meda Pharms

27 of 36
Drug Name	Cortisporin
PubMed Health	Hydrocortisone
Drug Classes	Anti-Inflammatory, Corticosteroid, Intermediate, Corticosteroid, Weak, Endocrine-Metabolic Agent, Gastrointestinal Agent, Hemorrhoidal Anti-Inflammatory, Hydrocortisone, Immune Suppressant
Active Ingredient	Hydrocortisone acetate; polymyxin b sulfate; Hydrocortisone; Bacitracin zinc; hydrocortisone; neomycin sulfate
Dosage Form	Solution/drops; Suspension/drops; Ointment; Cream
Route	Topical; Otic
Strength	400 units/gm; 10,000 units/gm; 0.5%; 10,000 units/ml; 1%; eq 3.5mg base/ml; eq 3.5mg base/gm; 5,000 units/gm
Market Status	Prescription
Company	Monarch Pharms; Citron Pharma

28 of 36
Drug Name	Hydrocortisone
Active Ingredient	Hydrocortisone
Dosage Form	Ointment; Enema; Tablet; Cream; Lotion
Route	Rectal; Oral; Topical
Strength	1%; 5mg; 10mg; 2.5%; 100mg/60ml; 20mg
Market Status	Prescription
Company	Vintage Pharms; Amedra Pharms; Taro; Fougera; Lyne; Fougera Pharms; Teva Pharms; Actavis Mid Atlantic; Vintage; Perrigo New York

29 of 36
Drug Name	Hydrocortisone and acetic acid
Drug Label	Topical corticosteroids constitute a class of primarily synthetic steroids used as anti-inflammatory and antipruritic agents. Texacort Topical Solution contains hydrocortisone as the active corticosteroid, having the chemical formula of Pregn-4-ene-3...
Active Ingredient	Acetic acid, glacial; hydrocortisone
Dosage Form	Solution/drops
Route	Otic
Strength	1%; 2%
Market Status	Prescription
Company	Taro; Vintage

30 of 36
Drug Name	Hydrocortisone in absorbase
Active Ingredient	Hydrocortisone
Dosage Form	Ointment
Route	Topical
Strength	1%
Market Status	Prescription
Company	Carolina Medcl

31 of 36
Drug Name	Hydro-rx
PubMed Health	Acetic Acid/Hydrocortisone (Into the ear)
Drug Classes	Anti-Infective/Anti-Inflammatory Combination
Drug Label	Glucocorticoids are adrenocortical steroids, both naturally occurring and synthetic, which are readily absorbed from the gastrointestinal tract.Hydrocortisone is a white to practically white, odorless, crystalline powder, very slightly soluble in wat...
Active Ingredient	Hydrocortisone
Dosage Form	Powder
Route	For rx compounding
Strength	100%
Market Status	Prescription
Company	X Gen Pharms

32 of 36
Drug Name	Nutracort
Active Ingredient	Hydrocortisone
Dosage Form	Lotion
Route	Topical
Strength	2.5%
Market Status	Prescription
Company	Dow Pharm

33 of 36
Drug Name	Stie-cort
Active Ingredient	Hydrocortisone
Dosage Form	Lotion
Route	Topical
Strength	2.5%
Market Status	Prescription
Company	Perrigo

34 of 36
Drug Name	Synacort
Active Ingredient	Hydrocortisone
Dosage Form	Cream
Route	Topical
Strength	1%; 2.5%
Market Status	Prescription
Company	Medicis

35 of 36
Drug Name	Texacort
Active Ingredient	Hydrocortisone
Dosage Form	Solution
Route	Topical
Strength	2.5%
Market Status	Prescription
Company	Mission Pharma

36 of 36
Drug Name	Vosol hc
Active Ingredient	Acetic acid, glacial; hydrocortisone
Dosage Form	Solution/drops
Route	Otic
Strength	1%; 2%
Market Status	Prescription
Company	Hi Tech Pharma

4.2 Therapeutic Uses

Anti-Inflammatory Agents, Steroidal

National Library of Medicine's Medical Subject Headings online file (MeSH, 1999)

MEDICATION (VET): Acute urticaria /can be treated by/ rapid-acting adrenocorticosteroids, eg, hydrocortisone ... .

Kahn, C.M. (Ed.); The Merck Veterinary Manual 9th ed. Merck & Co. Whitehouse Station, NJ. 2005, p. 690

MEDICATION (VET): /USED/ IV, IN PREVENTING OR TREATING ADRENAL FAILURE & SHOCK-LIKE CONDITIONS IN SURGICAL CASES WHICH HAVE BEEN ON CORTICOSTEROIDS, IN ACUTE ALLERGIC REACTIONS...IN POOR SURGICAL RISKS, & IN CASES WHICH HAVE HAD OVERWHELMING SYSTEMIC INFECTIONS...IN DOGS OR CATTLE...

Rossoff, I.S. Handbook of Veterinary Drugs. New York: Springer Publishing Company, 1974., p. 266

MEDICATION (VET) /EXPL:/: 5 Standardbreds and 4 Dutch Warmblood horses /were/ used to examine sensitivity of peripheral tissues to exogenous insulin 24 hours after administration of a single dose of hydrocortisone (0.06 mg/kg), eGH (20 ug/kg), or saline (0.9% NaCl) solution and after long-term administration (11 to 15 days) of eGH to horses. The amounts of metabolized glucose (M) and plasma insulin concentration (I) were determined. Values for M and the M-to-I ratio were significantly higher 24 hours after administration of a single dose of hydrocortisone than after single-dose administration of eGH or saline solution. After long-term administration of eGH, basal I concentration was increased and the mean M-to-I ratio was 22% lower, compared with values for horses treated with saline solution. Increases in M and the M-to-I ratio after a single dose of hydrocortisone imply that short-term hydrocortisone treatment increases glucose use by, and insulin sensitivity of, peripheral tissues. Assuming a single dose of hydrocortisone improves sensitivity of peripheral tissues to insulin, it may be an interesting candidate for use in reducing insulin resistance in peripheral tissues of horses with several disease states.

PMID:6334949 de Graaf-Roelfsema E et al; Am J Vet Res 66 (11): 1907-13 (2005)

For more Therapeutic Uses (Complete) data for HYDROCORTISONE (23 total), please visit the HSDB record page.

4.3 Drug Warning

It is not known whether rectal corticosteroids are distributed into breast milk. Systemic corticosteroids are distributed into breast milk and may cause unwanted effects, such as growth suppression, in the infant. Rectal corticosteroids are not recommended for use by breast-feeding mothers. /Corticosteroids, rectal/

Thomson/Micromedex. Drug Information for the Health Care Professional. Volume 1, Greenwood Village, CO. 2007., p. 913

The results of a prospective randomized controlled trial, which looked at the incidence of postoperative diabetes insipidus following the use of three different hydrocortisone protocols, and the results of a study, on the incidence of diabetes insipidus and cortisol response in patients not given hydrocortisone /was reported/. In study 1, 114 patients with pituitary macroadenoma were randomized into three groups: conventional dose (injected hydrocortisone 100 mg IV 6-hourly for 3 days); intermediate dose (injected hydrocortisone 100 mg IV 6-hourly on day 1, 100 mg IV 8-hourly on day 2, and 100 mg IV 12-hourly on day 3); low dose protocol (injected hydrocortisone 25 mg IV 6-hourly on day 1, 25 mg IV 8-hourly on day 2 and 25 mg IV 12-hourly on day 3). Radical excision was achieved in 92 patients. The incidence of diabetes insipidus with the conventional dose was 52%, intermediate dose, 36% and low dose, 24% (p = 0.025). Study 2 included 16 consecutive patients with Hardy's grade A & B pituitary adenoma. These patients were randomized to receive (Group I) or not receive (Group II) hydrocortisone. Patients in Group II demonstrated normal cortisol response intraoperatively and no patient developed features of hypocortisolism; the incidence of diabetes insipidus in this group was 14%. The low dose hydrocortisone protocol reduced the incidence of diabetes insipidus by 46% when compared with the conventional dose hydrocortisone protocol. In patients with grade A and B tumor with normal preoperative cortisol levels, the use of perioperative hydrocortisone can be avoided.

PMID:14635749 Rajaratnam S et al; Br J Neurosurg 17 (5): 437-42 (2003)

ACUTE ADRENAL INSUFFICIENCY RESULTS FROM TOO RAPID WITHDRAWAL OF CORTICOSTEROID THERAPY. /CORTICOSTEROIDS/

Goodman, L.S., and A. Gilman. (eds.) The Pharmacological Basis of Therapeutics. 5th ed. New York: Macmillan Publishing Co., Inc., 1975., p. 1496

POTENTIAL ADVERSE EFFECTS ON FETUS: Cleft palate, spontaneous abortions, and intrauterine growth retardation in animals. Potential for cleft palate formation and adrenal suppression in humans, although teratogenic effects have not been confirmed. POTENTIAL SIDE EFFECTS ON BREAST-FED INFANT: Passes into breast milk in small amounts. Administration of physiologic doses unlikely to adversely affect infant. FDA Category: C (C = Studies in laboratory animals have revealed adverse effects on the fetus (teratogenic, embryocidal, etc.) but there are no controlled studies in pregnant women. The benefits from use of the drug in pregnant women may be acceptable despite its potential risks, or there are no laboratory animal studies or adequate studies in pregnant women.) /Adrenocorticosteroids/ /from table II/

PMID:2195076 Stockton DL, Palle AS; J Am Acad Dermatol 23 (1): 87-103 (1990)

For more Drug Warnings (Complete) data for HYDROCORTISONE (31 total), please visit the HSDB record page.

4.4 Drug Indication

Otic solutions are indicated for infections of the external auditory canal caused by susceptible organisms and with inflammation. Hydrocortisone tablets are indicated for certain endocrine, rheumatic, collagen, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, gastrointestinal, and other conditions. A hydrocortisone enema is indicated for ulcerative colitis, a topical ointment with antibiotics is indicated for corticosteroid responsive dermatoses with infections, and a topical cream with [acyclovir] is indicated to treat cold sores. Oral granules of hydrocortisone are used as a replacement therapy for Adrenocortical Insufficiency (AI) in children under 17 years of age.

FDA Label

Replacement therapy of adrenal insufficiency in infants, children and adolescents (from birth to < 18 years old).

Treatment of adrenal insufficiency in adults.

Treatment of adrenocortical insufficiency

Treatment of congenital adrenal hyperplasia (CAH) in adolescents aged 12 years and over and adults.

5 Pharmacology and Biochemistry

5.1 Pharmacology

Hydrocortisone binds to the glucocorticoid receptor leading to downstream effects such as inhibition of phospholipase A2, NF-kappa B, other inflammatory transcription factors, and the promotion of anti-inflammatory genes. Hydrocortisone has a wide therapeutic index and a moderate duration of action. Patients should stop taking the medication if irritation or sensitization occurs.

5.2 MeSH Pharmacological Classification

Anti-Inflammatory Agents

Substances that reduce or suppress INFLAMMATION. (See all compounds classified as Anti-Inflammatory Agents.)

5.3 FDA Pharmacological Classification

5.3.1 Active Moiety

HYDROCORTISONE

5.3.2 FDA UNII

WI4X0X7BPJ

5.3.3 Pharmacological Classes

Corticosteroid [EPC]; Corticosteroid Hormone Receptor Agonists [MoA]

5.4 ATC Code

H02AB09

D07AA02

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355

A - Alimentary tract and metabolism

A01 - Stomatological preparations

A01A - Stomatological preparations

A01AC - Corticosteroids for local oral treatment

A01AC03 - Hydrocortisone

A - Alimentary tract and metabolism

A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents

A07E - Intestinal antiinflammatory agents

A07EA - Corticosteroids acting locally

A07EA02 - Hydrocortisone

C - Cardiovascular system

C05 - Vasoprotectives

C05A - Agents for treatment of hemorrhoids and anal fissures for topical use

C05AA - Corticosteroids

C05AA01 - Hydrocortisone

D - Dermatologicals

D07 - Corticosteroids, dermatological preparations

D07A - Corticosteroids, plain

D07AA - Corticosteroids, weak (group i)

D07AA02 - Hydrocortisone

D - Dermatologicals

D07 - Corticosteroids, dermatological preparations

D07X - Corticosteroids, other combinations

D07XA - Corticosteroids, weak, other combinations

D07XA01 - Hydrocortisone

H - Systemic hormonal preparations, excl. sex hormones and insulins

H02 - Corticosteroids for systemic use

H02A - Corticosteroids for systemic use, plain

H02AB - Glucocorticoids

H02AB09 - Hydrocortisone

S - Sensory organs

S01 - Ophthalmologicals

S01B - Antiinflammatory agents

S01BA - Corticosteroids, plain

S01BA02 - Hydrocortisone

S - Sensory organs

S01 - Ophthalmologicals

S01C - Antiinflammatory agents and antiinfectives in combination

S01CB - Corticosteroids/antiinfectives/mydriatics in combination

S01CB03 - Hydrocortisone

S - Sensory organs

S02 - Otologicals

S02B - Corticosteroids

S02BA - Corticosteroids

S02BA01 - Hydrocortisone

5.5 Absorption, Distribution and Excretion

Absorption

Oral hydrocortisone at a dose of 0.2-0.3mg/kg/day reached a mean C_max of 32.69nmol/L with a mean AUC of 90.63h\*nmol/L A 0.4-0.6mg/kg/day dose reached a mean C_max of 70.81nmol/L with a mean AUC of 199.11h\*nmol/L. However, the pharmacokinetics of hydrocortisone can vary by 10 times from patient to patient. Topical hydrocortisone cream is 4-19% bioavailable[8546995] with a T_max of 24h. Hydrocortisone retention enemas are have a bioavailability of 0.810 for slow absorbers and 0.502 in rapid absorbers. Slow absorbers take up hydrocortisone at a rate of 0.3610.255/h while fast absorbers take up hydrocortisone at a rate of 1.050.255/h. A 20mg IV dose of hydrocortisone has an AUC of 1163277ng\*h/mL.

Route of Elimination

Corticosteroids are eliminated predominantly in the urine. However, data regarding the exact proportion is not readily available.

Volume of Distribution

Total hydrocortisone has a volume of distribution of 39.82L, while the free fraction has a volume of distribution of 474.38L.

Clearance

Total hydrocortisone by the oral route has a mean clearance of 12.85L/h, while the free fraction has a mean clearance of 235.78L/h. A 20mg IV dose of hydrocortisone has a clearance of 18.24.2L/h.

Following percutaneous penetration of a topical corticosteroid, the drug that is systemically absorbed probably follows the metabolic pathways of systemically administered corticosteroids. Corticosteroids usually are metabolized in the liver and excreted by the kidneys. Some topical corticosteroids and their metabolites are excreted in bile. /Topical corticosteroids/

McEvoy, G.K. (ed.). American Hospital Formulary Service. AHFS Drug Information. American Society of Health-System Pharmacists, Bethesda, MD. 2007., p. 3525

Topical application of corticosteroids to the mucosa of the genitourinary or lower intestinal tract may result in substantial systemic absorption of the drugs. In healthy individuals, as much as 30-90% of rectally administered hydrocortisone as a retention enema may be absorbed. Greater amounts of hydrocortisone may be absorbed rectally if the intestinal mucosa is inflamed.

McEvoy, G.K. (ed.). American Hospital Formulary Service. AHFS Drug Information. American Society of Health-System Pharmacists, Bethesda, MD. 2007., p. 3525

Following topical application of a corticosteroid to most areas of normal skin, only minimal amounts of the drug reach the dermis and subsequently the systemic circulation; however, absorption is markedly increased when the skin has lost its keratin layer and can be increased by inflammation and/or diseases of the epidermal barrier (e.g., psoriasis, eczema). The drugs are absorbed to a greater degree from the scrotum, axilla, eyelid, face, and scalp than from the forearm, knee, elbow, palm, and sole. Even after washing the area being treated, prolonged absorption of the corticosteroid occurs, possibly because the drug is retained in the stratum corneum. /Topical corticosteroids/

McEvoy, G.K. (ed.). American Hospital Formulary Service. AHFS Drug Information. American Society of Health-System Pharmacists, Bethesda, MD. 2007., p. 3525

Percutaneous penetration of corticosteroids varies among individual patients and can be increased by the use of occlusive dressings, by increasing the concentration of the corticosteroid, and by using different vehicles. The use of an occlusive dressing with hydrocortisone for 96 hours substantially enhances percutaneous penetration of the drug; however, such use for up to 24 hours does not appear to alter penetration of topically applied hydrocortisone.

McEvoy, G.K. (ed.). American Hospital Formulary Service. AHFS Drug Information. American Society of Health-System Pharmacists, Bethesda, MD. 2007., p. 3525

For more Absorption, Distribution and Excretion (Complete) data for HYDROCORTISONE (15 total), please visit the HSDB record page.

5.6 Metabolism/Metabolites

Hydrocortisone is metabolised to 6-beta hydrocortisol via CYP3A, 5-beta tetrahydrocortisol via 3-oxo-5-beta-steroid 4-dehydrogenase, 5-alpha tetrahydrocortisol via 3-oxo-5-alpha-steroid 4-dehydrogenase 2, cortisone via Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticosteroid 11-beta-dehydrogenase isozyme 2, and glucuronide products. Cortisone is further metabolized to tetrahydrocortisone and dihydrocortisol.

A study was made of the absorption of exogenous hydrocortisone and formation of its metabolites in isolated liver of intact and exposed rats in conditions of recirculating perfusion. It was shown that the absorption of the hormone by the liver of irradiated rats was greatly lowered but the content of most metabolites found in the perfused medium of irradiated liver increased as compared to the control. It is suggested that irradiation inhibits subsequent transformations of the hydrocortisone metabolism products.

PMID:4001319 Litskevich LA, Dokshina GA; Radiobiologiia 25 (2): 200-3 (1985)

Subcellular distribution of (3)H-hydrocortisone and its metabolites in the liver and kidney of intact and alloxan diabetic rats was investigated. Ten minutes after the administration of this hormone several metabolites (mostly tetrahydrocortisol) and the native hormone were found in liver cytosol, microsomes, mitochondria and nuclei, the relative content of individual compounds in various subcellular fractions being different. In liver mitochondria, microsomes and nuclei of alloxan diabetic rats the concentration of tetrahydrocortisol was decreased, while that of native hormone was increased as compared to normal animals. It was suggested that such changes found in diabetic animals may be one of the causes of increased sensitivity of transcription and translation processes to glucocorticoids. In kidney cytosol and microsomes of intact rats cortisone and tetrahydrocortisol were found. In diabetic animals, however, the concentration of tetrahydrocortisol increased, while that of cortisone was undetectable.

PMID:3259502 Minchenko AG, Tronjko ND; Endocrinol Exp 22 (1): 19-28 (1988)

5.7 Biological Half-Life

Total hydrocortisone via the oral route has a half life of 2.15h while the free fraction has a half life of 1.39h. A 20mg IV dose of hydrocortisone has a terminal half life of 1.90.4h.

... After IV administration, hydrocortisone was eliminated with a total body clearance of 18 L/hr and a half-life of 1.7 hr.

PMID:2050835 Derendorf H et al; J Clin Pharmacol 31 (5): 473-6 (1991)

5.8 Mechanism of Action

The short term effects of corticosteroids are decreased vasodilation and permeability of capillaries, as well as decreased leukocyte migration to sites of inflammation. Corticosteroids binding to the glucocorticoid receptor mediates changes in gene expression that lead to multiple downstream effects over hours to days. Glucocorticoids inhibit neutrophil apoptosis and demargination; they inhibit phospholipase A2, which decreases the formation of arachidonic acid derivatives; they inhibit NF-Kappa B and other inflammatory transcription factors; they promote anti-inflammatory genes like interleukin-10. Lower doses of corticosteroids provide an anti-inflammatory effect, while higher doses are immunosuppressive. High doses of glucocorticoids for an extended period bind to the mineralocorticoid receptor, raising sodium levels and decreasing potassium levels.

Following topical application, corticosteroids produce anti-inflammatory, antipruritic, and vasoconstrictor actions. The activity of the drugs is thought to result at least in part from binding with a steroid receptor. Corticosteroids decrease inflammation by stabilizing leukocyte lysosomal membranes, preventing release of destructive acid hydrolases from leukocytes; inhibiting macrophage accumulation in inflamed areas; reducing leukocyte adhesion to capillary endothelium; reducing capillary wall permeability and edema formation; decreasing complement components; antagonizing histamine activity and release of kinin from substrates; reducing fibroblast proliferation, collagen deposition, and subsequent scar tissue formation; and possibly by other mechanisms as yet unknown. Corticosteroids, especially the fluorinated corticosteroids, have antimitotic activity on cutaneous fibroblasts and the epidermis. /Corticosteroids/

McEvoy, G.K. (ed.). American Hospital Formulary Service. AHFS Drug Information. American Society of Health-System Pharmacists, Bethesda, MD. 2007., p. 3525

Reactive oxygen species (ROS) generation by polymorphonuclear leukocytes (PMNL) and mononuclear cells (MNC) is inhibited following the intravenous administration of hydrocortisone. This is associated with a parallel decrease in intranuclear NFkappaB, known to modulate inflammatory responses including ROS generation. Plasma levels of interleukin-10 (IL-10), an anti-inflammatory and immunosuppressive cytokine produced by TH2 cells, are also increased after hydrocortisone administration. In this study, we have investigated the effect of hydrocortisone on p47(phox) subunit, a key component of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, in MNC and the pharmacodynamics of this effect with ROS generation and plasma IL-10 levels /were investigated/. p47(phox) subunit protein levels in MNC showed a progressive decrease after hydrocortisone administration. It reached a nadir at 4 hours and increased thereafter to a baseline level at 24 hours. ROS generation also decreased, reached a nadir between 2 and 4 hours, and returned to a baseline level at 24 hours. IL-10 concentrations increased, peaked at 4 hours, and reverted to the baseline levels at 24 hours. In conclusion, p47(phox) subunit suppression may contribute to the inhibition of ROS generation in MNC after hydrocortisone administration. This suppression occurs in parallel with the suppression of NFkappaB and an increase in IL-10 plasma levels. Therefore, it would appear that the decrease in intranuclear NFkappaB and an increase in IL-10 may cause the inhibitory modulation on p47(phox) subunit and ROS generation by MNC following hydrocortisone and other glucocorticoids.

PMID:11319715 Dandona P et al; Metabolism 50 (5): 548-52 (2001)

API SUPPLIERS

01

EUROAPI

France

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #5A113

EUROAPI, the leading small molecules API player, provides both API sales & CDMO services.

Contact Supplier

France

Virtual Booth

Digital Content

USDMF CEP/COS

JDMF

EU-WC NDC

KDMF

VMF ROW

AUDIT

02

Pfizer CentreOne

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Contract Pharma 2024

Attending

Pfizer CentreOne is a global CDMO and a leading supplier of Specialty APIs.

Contact Supplier

U.S.A

Virtual Booth

Digital Content

USDMF

CEP/COS

JDMF

EU-WC NDC KDMF VMF Others AUDIT

03

Symbiotec Pharmalab

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #2A58

Symbiotec: Global API manufacturer, specializing in Cortico-Steroids & Steroid-Hormone APIs.

Contact Supplier

India

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC

NDC

KDMF VMF Others AUDIT

Corporate PDF

04

Axplora

Germany

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #2A18

Axplora- The partner of choice for complex APIs.

Contact Supplier

Germany

Virtual Booth

Digital Content

USDMF

CEP/COS JDMF EU-WC NDC KDMF VMF EU

AUDIT

Product Web Link

05

Sanofi

France

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Attending

Sanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

Contact Supplier

France

Virtual Booth

Digital Content

USDMF

CEP/COS JDMF EU-WC NDC

KDMF VMF Others AUDIT

Portfolio PDF

Product Web Link

06

Rochem International Inc

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #3F18

Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

Contact Supplier

U.S.A

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

07

Gonane Pharma

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Attending

Gonane has API manufacturing expertise in new-age Corticosteroids, Hormones and other pharma raw materials.

Contact Supplier

India

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

Product Web Link

08

Pharm-RX Chemical

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Attending

Pharm-Rx is a reputed global importer and distributor of pharmaceutical active ingredients.

Contact Supplier

U.S.A

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

Corporate PDF

09

HRV Global Life Sciences

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #3A25

HRV Global Life Sciences - Market Expansion Leader in Pharmaceuticals.

Contact Supplier

India

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF AU

AUDIT

10

Bioquim

Spain

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Attending

Bioquim: An European GMP-certified company manufacturing bulk APIs, specializing in sterile lyophilization and chemical synthesis.

Contact Supplier

Spain

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

Corporate PDF

Only 10 entries up to this point, click to access all

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

USDMF

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

CEP/COS

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

JDMF

01

EUROAPI FRANCE

France

CPhI Worldwide, Milan

Booth #5A113

EUROAPI, the leading small molecules API player, provides both API sales & CDMO services.

Contact Supplier

France

Virtual Booth

Digital Content

hydrocortisone

Registration Number : 218MF10377

Registrant's Address : 15 rue Traversie(')re 75012 Paris France

Initial Date of Registration : 2006-03-20

Latest Date of Registration : 2019-11-27

02

EUROAPI FRANCE

France

CPhI Worldwide, Milan

Booth #5A113

EUROAPI, the leading small molecules API player, provides both API sales & CDMO services.

Contact Supplier

France

Virtual Booth

Digital Content

hydrocortisone sodium phosphate

Registration Number : 220MF10093

Registrant's Address : 15 rue Traversie(')re 75012 Paris France

Initial Date of Registration : 2008-03-28

Latest Date of Registration : 2022-06-22

03

EUROAPI FRANCE

France

CPhI Worldwide, Milan

Booth #5A113

EUROAPI, the leading small molecules API player, provides both API sales & CDMO services.

Contact Supplier

France

Virtual Booth

Digital Content

hydrocortisone

Registration Number : 228MF10090

Registrant's Address : 15 rue Traversie(')re 75012 Paris France

Initial Date of Registration : 2016-04-15

Latest Date of Registration : 2021-03-05

04

Pfizer Inc.

U.S.A

Contract Pharma 2024

Attending

Pfizer CentreOne is a global CDMO and a leading supplier of Specialty APIs.

Contact Supplier

U.S.A

Virtual Booth

Digital Content

Hydrocortisone

Registration Number : 222MF10138

Registrant's Address : 235 East 42nd Street, New York, NY 10017

Initial Date of Registration : 2010-04-14

Latest Date of Registration : 2023-03-23

05

Curia Spain SAU

U.S.A

BioProcess International

Not Confirmed

06

Henan Lihua Pharmaceutical Co., Ltd...

China

BioProcess International

Not Confirmed

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

EU WC

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

KDMF

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

NDC API

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

VMF

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Listed Suppliers

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

API Reference Price

[{"dataSource":"API Export","activeIngredients":"HYDROCORTISONE","year":"2021","qtr":"Q1","strtotime":1611772200,"product":"HYDROCORTISONE EP (MICRONISED)","address":"385\/2, GRAM PIGDEMBER,","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"MUNICH","customer":"FLAVINE","customerCountry":"GERMANY","quantity":"225.00","actualQuantity":"225","unit":"KGS","unitRateFc":"653.3","totalValueFC":"144916","currency":"USD","unitRateINR":47105.333333333336,"date":"28-Jan-2021","totalValueINR":"10598700","totalValueInUsd":"144916","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372900","bill_no":"4001423","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Micronized","supplierPort":"Indore-EPZ\/SEZ","supplierAddress":"385\/2, GRAM PIGDEMBER,, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"HYDROCORTISONE ACETATE","year":"2021","qtr":"Q1","strtotime":1614450600,"product":"HYDROCORTISONE ACETATE IP","address":"70, PRINCESS STREET, RANVIR BUILDING, 2ND FLOOR,","city":"MUMBAI, MAHARASHTRA.","supplier":"PREMIER DRUG HOUSE","supplierCountry":"INDIA","foreign_port":"BIRGUNJ","customer":"NOVA GENETICA PVT ","customerCountry":"NEPAL","quantity":"2.50","actualQuantity":"2500","unit":"GMS","unitRateFc":"0.5","totalValueFC":"1184.6","currency":"USD","unitRateINR":34.500003999999997,"date":"28-Feb-2021","totalValueINR":"86250.01","totalValueInUsd":"1184.6","indian_port":"RAXAUL","hs_no":"29372100","bill_no":"8998867","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"NEPAL","selfForZScoreResived":"Pharma Grade","supplierPort":"RAXAUL","supplierAddress":"70, PRINCESS STREET, RANVIR BUILDING, 2ND FLOOR,, MUMBAI, MAHARASHTRA.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"HYDROCORTISONE","year":"2021","qtr":"Q1","strtotime":1616783400,"product":"HYDROCORTISONE USP (MICRONISED)","address":"385\/2, GRAM PIGDEMBER,","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"CLOSTER\/NEW JERSEY","customer":"FLAVINE","customerCountry":"UNITED STATES","quantity":"12.00","actualQuantity":"12","unit":"KGS","unitRateFc":"500","totalValueFC":"5901","currency":"USD","unitRateINR":35800,"date":"27-Mar-2021","totalValueINR":"429600","totalValueInUsd":"5901","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372900","bill_no":"4005124","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Micronized","supplierPort":"Indore-EPZ\/SEZ","supplierAddress":"385\/2, GRAM PIGDEMBER,, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"HYDROCORTISONE SODIUM SUCCINATE","year":"2021","qtr":"Q2","strtotime":1619029800,"product":"HYDROCORTISONE SODIUM SUCCINATE FOR INJE CTION (LYOPHILISED STERILE BULK)","address":"304,?TOWN?CENTRE,?ANDHERI?KURLAROAD,?ANDHERI?(EAST),","city":"MUMBAI?\/?MAHARASHTRA","supplier":"MAC-CHEM PRODUCTS (INDIA) PVT.LTD","supplierCountry":"INDIA","foreign_port":"HANOI - NOIBAI","customer":"VINH PHUC PHARMACEUTICAL ","customerCountry":"VIETNAM","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"400.1","totalValueFC":"3871.8","currency":"USD","unitRateINR":28825,"date":"22-Apr-2021","totalValueINR":"288250","totalValueInUsd":"3871.8","indian_port":"BOMBAY AIR","hs_no":"29372100","bill_no":"1300249","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"VIETNAM, DEMOCRATIC REP. OF","selfForZScoreResived":"Sterile","supplierPort":"BOMBAY AIR","supplierAddress":"304,?TOWN?CENTRE,?ANDHERI?KURLAROAD,?ANDHERI?(EAST),, MUMBAI?\/?MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q2","strtotime":1624473000,"product":"HYDROCORTISONE ACETATE BP (MICRONISED)","address":"385\/2, GRAM PIGDEMBER,","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"KARACHI","customer":"GSK","customerCountry":"PAKISTAN","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"497","totalValueFC":"49229.9","currency":"USD","unitRateINR":36206.449999999997,"date":"24-Jun-2021","totalValueINR":"3620645","totalValueInUsd":"49229.9","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372200","bill_no":"4010164","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Micronized","supplierPort":"Indore-EPZ\/SEZ","supplierAddress":"385\/2, GRAM PIGDEMBER,, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1628101800,"product":"HYDROCORTISONE SODIUM SUCCINATE FOR INJE CTION USP FOR MANUFACTURERS USE","address":"385\/2, GRAM PIGDEMBER,NEAR HOTEL MASHAL, RAU","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES","customer":"KLONAL SRL","customerCountry":"ARGENTINA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"460.5","totalValueFC":"44731.3","currency":"USD","unitRateINR":33176.055,"date":"05-Aug-2021","totalValueINR":"3317605.5","totalValueInUsd":"44731.3","indian_port":"BOMBAY AIR","hs_no":"29372900","bill_no":"3637713","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"385\/2, GRAM PIGDEMBER,NEAR HOTEL MASHAL, RAU, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1630348200,"product":"HYDROCORTISONE SOD. SUCC.FOR INJ.(LYOPHI LISED STERILE BULK)","address":"304,?TOWN?CENTRE,?ANDHERI?KURLAROAD,?ANDHERI?(EAST),","city":"MUMBAI?\/?MAHARASHTRA","supplier":"MAC-CHEM PRODUCTS (INDIA) PVT.LTD","supplierCountry":"INDIA","foreign_port":"JAKARTA","customer":"PT EUTHICA UNGGUL ","customerCountry":"INDONESIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"571.5","totalValueFC":"2775.8","currency":"USD","unitRateINR":41175.099999999999,"date":"31-Aug-2021","totalValueINR":"205875.5","totalValueInUsd":"2775.8","indian_port":"BOMBAY AIR","hs_no":"29372100","bill_no":"4239891","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"INDONESIA","selfForZScoreResived":"Sterile","supplierPort":"BOMBAY AIR","supplierAddress":"304,?TOWN?CENTRE,?ANDHERI?KURLAROAD,?ANDHERI?(EAST),, MUMBAI?\/?MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1631212200,"product":"HYDROCORTISONE ACETATE USP MICRONISED","address":"3, BOTAWALA BLDG., 1ST FLOOR, BANK STREET, BEHIND SBI, FORT","city":"MUMBAI","supplier":"NISHCHEM INTERNATIONAL PVT. LTD","supplierCountry":"INDIA","foreign_port":"BIRGUNJ","customer":"NATIONAL HEALTHCARE PVT ","customerCountry":"NEPAL","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"40000","totalValueFC":"543.8","currency":"INR","unitRateINR":40000,"date":"10-Sep-2021","totalValueINR":"40000","totalValueInUsd":"543.8","indian_port":"RAXAUL","hs_no":"29372100","bill_no":"4505136","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"NEPAL","selfForZScoreResived":"Micronized","supplierPort":"RAXAUL","supplierAddress":"3, BOTAWALA BLDG., 1ST FLOOR, BANK STREET, BEHIND SBI, FORT, MUMBAI","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1635359400,"product":"HYDROCORTISONE ACETATE IP","address":"44-FAIZ-E-EDROOS,371-373 NARSI NATHA STREET,MASJID BUNDER","city":"MUMBAI ,MAHARASHTRA","supplier":"JAYANA PHARMA","supplierCountry":"INDIA","foreign_port":"KATHMANDU","customer":"NOVA GENETICA P ","customerCountry":"NEPAL","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"32500","totalValueFC":"2175.9","currency":"INR","unitRateINR":32600,"date":"28-Oct-2021","totalValueINR":"163000","totalValueInUsd":"2175.9","indian_port":"RAXAUL","hs_no":"29372100","bill_no":"5633635","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"NEPAL","selfForZScoreResived":"Pharma Grade","supplierPort":"RAXAUL","supplierAddress":"44-FAIZ-E-EDROOS,371-373 NARSI NATHA STREET,MASJID BUNDER, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1635705000,"product":"HYDROCORTISONE SODIUM SUCCINATE FOR INJE","address":"385\/2, GRAM PIGDEMBER,NEAR HOTEL MASHAL, RAU","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"ISLAMABAD - ISLAMABA","customer":"MEEZAN BANK LTD","customerCountry":"PAKISTAN","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"390","totalValueFC":"19148.3","currency":"USD","unitRateINR":28520,"date":"01-Nov-2021","totalValueINR":"1426000","totalValueInUsd":"19148.3","indian_port":"BOMBAY AIR","hs_no":"29372900","bill_no":"5750185","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"385\/2, GRAM PIGDEMBER,NEAR HOTEL MASHAL, RAU, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1639506600,"product":"HYDROCORTISONE SODIUM SUCCINATE FOR INJE","address":"385\/2, GRAM PIGDEMBER,,NEAR HOTEL MASHAL, RAU","city":"INDORE,MADHYA PRADESH","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES","customer":"KLONAL SRL","customerCountry":"ARGENTINA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"430","totalValueFC":"41590.3","currency":"USD","unitRateINR":31370,"date":"15-Dec-2021","totalValueINR":"3137000","totalValueInUsd":"41590.3","indian_port":"BOMBAY AIR","hs_no":"29372900","bill_no":"6753582","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"385\/2, GRAM PIGDEMBER,,NEAR HOTEL MASHAL, RAU, INDORE,MADHYA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1640889000,"product":"HYDROCORTISONE ACETATE BP(MICRONISED)","address":"385\/2, GRAM PIGDEMBER,","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"KARACHI","customer":"GSK","customerCountry":"PAKISTAN","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"497","totalValueFC":"12223.9","currency":"USD","unitRateINR":36879.959999999999,"date":"31-Dec-2021","totalValueINR":"921999","totalValueInUsd":"12223.9","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372900","bill_no":"4020854","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Micronized","supplierPort":"Indore-EPZ\/SEZ","supplierAddress":"385\/2, GRAM PIGDEMBER,, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1642962600,"product":"HYDROCORTISONE HEMISUCCINATE BP\/PHEUR\/US","address":"385\/2, GRAM PIGDEMBER,,NEAR HOTEL MASHAL, RAU","city":"INDORE,MADHYA PRADESH","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"GUARULHOS","customer":"EUROFARMA LABORATORIOS S.A","customerCountry":"BRAZIL","quantity":"0.50","actualQuantity":"0.5","unit":"KGS","unitRateFc":"1200","totalValueFC":"510.1","currency":"USD","unitRateINR":76000,"date":"24-Jan-2022","totalValueINR":"38000","totalValueInUsd":"510.1","indian_port":"BOMBAY AIR","hs_no":"29372900","bill_no":"7710425","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"385\/2, GRAM PIGDEMBER,,NEAR HOTEL MASHAL, RAU, INDORE,MADHYA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1644517800,"product":"HYDROCORTISONE ACETATE","address":"29-B, RABINDRA SARANI,,2ND FLOOR, ROOM NO 15","city":"KOLKATA,WEST BENGAL","supplier":"K KUMAR & ","supplierCountry":"INDIA","foreign_port":"KATHMANDU","customer":"NOVA GENETICA PVT ","customerCountry":"NEPAL","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"36000","totalValueFC":"1454.2","currency":"INR","unitRateINR":36333.333333333336,"date":"11-Feb-2022","totalValueINR":"109000","totalValueInUsd":"1454.2","indian_port":"RAXAUL","hs_no":"29372100","bill_no":"8151006","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"NEPAL","selfForZScoreResived":"Pharma Grade","supplierPort":"RAXAUL","supplierAddress":"29-B, RABINDRA SARANI,,2ND FLOOR, ROOM NO 15, KOLKATA,WEST BENGAL","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1649788200,"product":"HYDROCORTISONE ACETATE USP 43 ( MICRONI","address":"A-501, KRISHNA REGENCY, KRISHNA ENCLAVE, DATTA MANDIR ROAD,","city":"VAKOLA, SANTACRUZ EAST, MUMBAI","supplier":"PHARMACREST COMPANY PRIVATE ","supplierCountry":"INDIA","foreign_port":"UMM QASR","customer":"BUYER","customerCountry":"IRAQ","quantity":"12.00","actualQuantity":"12","unit":"KGS","unitRateFc":"490","totalValueFC":"5858.3","currency":"USD","unitRateINR":36833.333333333336,"date":"13-Apr-2022","totalValueINR":"442000","totalValueInUsd":"5858.3","indian_port":"JNPT","hs_no":"29372100","bill_no":"9668383","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"IRAQ","selfForZScoreResived":"Pharma Grade","supplierPort":"JNPT","supplierAddress":"A-501, KRISHNA REGENCY, KRISHNA ENCLAVE, DATTA MANDIR ROAD,, VAKOLA, SANTACRUZ EAST, MUMBAI","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1651257000,"product":"HYDROCORTISONE USP (MICRONISED)","address":"385\/2, GRAM PIGDEMBER,","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"CLOSTER\/NEW JERSEY","customer":"FLAVINE","customerCountry":"UNITED STATES","quantity":"15.00","actualQuantity":"15","unit":"KGS","unitRateFc":"570.7","totalValueFC":"8560.1","currency":"USD","unitRateINR":43056.800000000003,"date":"30-Apr-2022","totalValueINR":"645852","totalValueInUsd":"8560.1","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372900","bill_no":"4006237","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Micronized","supplierPort":"Indore-EPZ\/SEZ","supplierAddress":"385\/2, GRAM PIGDEMBER,, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1652121000,"product":"HYDROCORTISONE ACETATE","address":"GROUND FLOOR, 1, PLOT-273, RAMA BAUG, DEODHAR ROAD, NAPPU GARD","city":"MUMBAI","supplier":"HONEY DRUGS","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES, BA","customer":"TO THE ORDER OF","customerCountry":"ARGENTINA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"690","totalValueFC":"1345.7","currency":"USD","unitRateINR":52000,"date":"10-May-2022","totalValueINR":"104000","totalValueInUsd":"1345.7","indian_port":"BOMBAY AIR","hs_no":"29372200","bill_no":"1302444","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"GROUND FLOOR, 1, PLOT-273, RAMA BAUG, DEODHAR ROAD, NAPPU GARD, MUMBAI","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1653417000,"product":"HYDROCORTISONE SODIUM SUCCINATE FOR","address":"385\/2, GRAM PIGDEMBER,","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"GUARULHOS","customer":"ASHFORD INVEST & TRADE INC","customerCountry":"BRAZIL","quantity":"600.00","actualQuantity":"600","unit":"KGS","unitRateFc":"467.8","totalValueFC":"279249.3","currency":"USD","unitRateINR":35969.974999999999,"date":"25-May-2022","totalValueINR":"21581985","totalValueInUsd":"279249.3","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372100","bill_no":"4007416","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"Indore-EPZ\/SEZ","supplierAddress":"385\/2, GRAM PIGDEMBER,, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1655749800,"product":"HYDROCORTISONE ACETATE IP","address":"44-FAIZ-E-EDROOS,371-373,NARSI NAT HA STREET,MASJID BUNDER","city":"MUMBAI,MAHARASHTRA","supplier":"JAYANA PHARMA","supplierCountry":"INDIA","foreign_port":"KATHMANDU","customer":"CUREX PHARMACEUTICALS P ","customerCountry":"NEPAL","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"37080","totalValueFC":"474.3","currency":"INR","unitRateINR":37000,"date":"21-Jun-2022","totalValueINR":"37000","totalValueInUsd":"474.3","indian_port":"RAXAUL","hs_no":"29372100","bill_no":"2270736","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"NEPAL","selfForZScoreResived":"Pharma Grade","supplierPort":"RAXAUL","supplierAddress":"44-FAIZ-E-EDROOS,371-373,NARSI NAT HA STREET,MASJID BUNDER, MUMBAI,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1659033000,"product":"HYDROCORTISONE ACETATE USP","address":"385\/2, GRAM PIGDEMBER,","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"BARCELONA","customer":"CHEMO","customerCountry":"SPAIN","quantity":"35.00","actualQuantity":"35","unit":"KGS","unitRateFc":"592.4","totalValueFC":"20650","currency":"USD","unitRateINR":46914.800000000003,"date":"29-Jul-2022","totalValueINR":"1642018","totalValueInUsd":"20650","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372100","bill_no":"4010928","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"Indore-EPZ\/SEZ","supplierAddress":"385\/2, GRAM PIGDEMBER,, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1660242600,"product":"HYDROCORTISONE HEMISUCCINATE BP\/PHEUR\/US","address":"385\/2, GRAM PIGDEMBER,,NEAR HOTEL MASHAL, RAU","city":"INDORE,MADHYA PRADESH","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"MUNICH","customer":"TO THE ORDER","customerCountry":"GERMANY","quantity":"15.00","actualQuantity":"15","unit":"KGS","unitRateFc":"1200","totalValueFC":"17406.7","currency":"USD","unitRateINR":92333.333333333328,"date":"12-Aug-2022","totalValueINR":"1385000","totalValueInUsd":"17406.7","indian_port":"BOMBAY AIR","hs_no":"29372900","bill_no":"3464583","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"385\/2, GRAM PIGDEMBER,,NEAR HOTEL MASHAL, RAU, INDORE,MADHYA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1660761000,"product":"HYDROCORTISONE EP (MICRONISED)","address":"385\/2, GRAM PIGDEMBER,","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"MUNICH","customer":"FLAVINE","customerCountry":"GERMANY","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"704.8","totalValueFC":"138531.1","currency":"USD","unitRateINR":55112.644999999997,"date":"18-Aug-2022","totalValueINR":"11022529","totalValueInUsd":"138531.1","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372100","bill_no":"4011820","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Micronized","supplierPort":"Indore-EPZ\/SEZ","supplierAddress":"385\/2, GRAM PIGDEMBER,, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1664303400,"product":"HYDROCORTISONE SODIUM SUCCINATE FOR INJE","address":"PLOT NO.2516 & 2518, G.I.D.C. SARIGAM, TAL: UMBERGAON,","city":"DIST: VALSAD\/GUJARAT","supplier":"ARIHANTANAM LIFECARE PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"BANGKOK","customer":"ABLE MEDICAL COMPANY ","customerCountry":"THAILAND","quantity":"30.00","actualQuantity":"30","unit":"KGS","unitRateFc":"470","totalValueFC":"13626","currency":"USD","unitRateINR":36400,"date":"28-Sep-2022","totalValueINR":"1092000","totalValueInUsd":"13626","indian_port":"BOMBAY AIR","hs_no":"29379090","bill_no":"4496676","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"THAILAND","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"PLOT NO.2516 & 2518, G.I.D.C. SARIGAM, TAL: UMBERGAON,, DIST: VALSAD\/GUJARAT","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1664994600,"product":"HYDROCORTISONE ACETATE BP (STERILE,","address":"385\/2, GRAM PIGDEMBER,","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"DHAKA","customer":"POPULAR PHARMACEUTICALS LTD.","customerCountry":"BANGLADESH","quantity":"30.00","actualQuantity":"30","unit":"KGS","unitRateFc":"926.2","totalValueFC":"26576.4","currency":"USD","unitRateINR":72894.03333333334,"date":"06-Oct-2022","totalValueINR":"2186821","totalValueInUsd":"26576.4","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372100","bill_no":"4014344","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BANGLADESH","selfForZScoreResived":"Sterile","supplierPort":"Indore-EPZ\/SEZ","supplierAddress":"385\/2, GRAM PIGDEMBER,, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1664994600,"product":"HYDROCORTISONE ACETATE BP (MICRONISED)","address":"385\/2, GRAM PIGDEMBER,","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"KARACHI","customer":"GSK","customerCountry":"PAKISTAN","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"491","totalValueFC":"23480.6","currency":"USD","unitRateINR":38641.699999999997,"date":"06-Oct-2022","totalValueINR":"1932085","totalValueInUsd":"23480.6","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372900","bill_no":"4014342","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Micronized","supplierPort":"Indore-EPZ\/SEZ","supplierAddress":"385\/2, GRAM PIGDEMBER,, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1665340200,"product":"HYDROCORTISONE ACETATE USP MICRONISED","address":"3 BOTAWALA BLDG 1ST FLOOR,BANK STR EET BEHIND SBI FORT","city":"MUMBAI,MAHARASHTRA","supplier":"NISHCHEM INTERNATIONAL PVT. LTD","supplierCountry":"INDIA","foreign_port":"BIRGUNJ","customer":"TO THE ORDER OF NATIONAL HEALTHCARE","customerCountry":"NEPAL","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"38000","totalValueFC":"461.8","currency":"INR","unitRateINR":38000,"date":"10-Oct-2022","totalValueINR":"38000","totalValueInUsd":"461.8","indian_port":"RAXAUL","hs_no":"29372100","bill_no":"4718623","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"NEPAL","selfForZScoreResived":"Micronized","supplierPort":"RAXAUL","supplierAddress":"3 BOTAWALA BLDG 1ST FLOOR,BANK STR EET BEHIND SBI FORT, MUMBAI,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1666290600,"product":"HYDROCORTISONE ACETATE(SUPPLR:MAHARSHI P","address":"AT POST KHERGAM BANDHAD FALIYA, KHERGAM-VALSAD ROAD, TAL-KHERGAM Co","city":"NAVSARI","supplier":"GANGOTRI ORGANICS","supplierCountry":"INDIA","foreign_port":"MATADI","customer":"PROMED S.A.R.L","customerCountry":"CONGO, THE DEMOCRATIC REPUBLIC","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"531","totalValueFC":"5310.9","currency":"USD","unitRateINR":43700,"date":"21-Oct-2022","totalValueINR":"437000","totalValueInUsd":"5310.9","indian_port":"JNPT","hs_no":"29372100","bill_no":"5004785","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"CONGO, THE DEMOCRATIC REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"JNPT","supplierAddress":"AT POST KHERGAM BANDHAD FALIYA, KHERGAM-VALSAD ROAD, TAL-KHERGAM Co, NAVSARI","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1666981800,"product":"HYDROCORTISONE SOD. SUCC. FOR INJ.(LYOPH","address":"304, Town Centre, Andheri Kurla Road, Andheri East","city":"MUMBAI","supplier":"MAC-CHEM PRODUCTS (INDIA) PVT.LTD","supplierCountry":"INDIA","foreign_port":"ISLAMABAD - ISLAMABA","customer":"HABIB METROPOLITAN BANK ","customerCountry":"PAKISTAN","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"380","totalValueFC":"37953.8","currency":"USD","unitRateINR":31230,"date":"29-Oct-2022","totalValueINR":"3123000","totalValueInUsd":"37953.8","indian_port":"BOMBAY AIR","hs_no":"29372100","bill_no":"5117151","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"304, Town Centre, Andheri Kurla Road, Andheri East, MUMBAI","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1667154600,"product":"HYDROCORTISONE ACETATE USP (MICRONISED)","address":"385\/2, GRAM PIGDEMBER,","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"CLOSTER\/NEW JERSEY","customer":"FLAVINE","customerCountry":"UNITED STATES","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"678.8","totalValueFC":"33905.3","currency":"USD","unitRateINR":55797.360000000001,"date":"31-Oct-2022","totalValueINR":"2789868","totalValueInUsd":"33905.3","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372900","bill_no":"4015528","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Micronized","supplierPort":"Indore-EPZ\/SEZ","supplierAddress":"385\/2, GRAM PIGDEMBER,, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1667845800,"product":"HYDROCORTISONE SODIUM SUCCINATE FOR INJE","address":"385\/2, GRAM PIGDEMBER,,NEAR HOTEL MASHAL, RAU","city":"INDORE,MADHYA PRADESH","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES","customer":"TO THE ORDER","customerCountry":"ARGENTINA","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"360","totalValueFC":"70062.7","currency":"USD","unitRateINR":28590,"date":"08-Nov-2022","totalValueINR":"5718000","totalValueInUsd":"70062.7","indian_port":"BOMBAY AIR","hs_no":"29372900","bill_no":"5316340","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"385\/2, GRAM PIGDEMBER,,NEAR HOTEL MASHAL, RAU, INDORE,MADHYA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1669746600,"product":"HYDROCORTISONE ACETATE USP (MICRONISED)","address":"385\/2, GRAM PIGDEMBER,","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"DUBAI","customer":"CHEMO","customerCountry":"UNITED ARAB EMIRATES","quantity":"20.00","actualQuantity":"20","unit":"KGS","unitRateFc":"586","totalValueFC":"11617.3","currency":"USD","unitRateINR":47405.800000000003,"date":"30-Nov-2022","totalValueINR":"948116","totalValueInUsd":"11617.3","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372900","bill_no":"4017174","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"UNITED ARAB EMIR","selfForZScoreResived":"Micronized","supplierPort":"Indore-EPZ\/SEZ","supplierAddress":"385\/2, GRAM PIGDEMBER,, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1670005800,"product":"HYDROCORTISONE ACETATE BP (STERILE, MICR","address":"","city":"","supplier":"APOTECA PHARMA PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"MOSCOW DOMODEDOVO","customer":"FAVORIT TRADE JSC","customerCountry":"RUSSIA","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"1243.7","totalValueFC":"12535.5","currency":"EUR","unitRateINR":103300,"date":"03-Dec-2022","totalValueINR":"1033000","totalValueInUsd":"12535.5","indian_port":"BOMBAY AIR","hs_no":"29372100","bill_no":"5901296","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"RUSSIA","selfForZScoreResived":"Sterile","supplierPort":"BOMBAY AIR","supplierAddress":"","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1670178600,"product":"HYDROCORTISONE ACETATE BP (STERILE, MICR","address":"","city":"","supplier":"APOTECA PHARMA PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"MOSCOW DOMODEDOVO","customer":"FAVORIT TRADE JSC","customerCountry":"RUSSIA","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"1243.7","totalValueFC":"12438.4","currency":"EUR","unitRateINR":102500,"date":"05-Dec-2022","totalValueINR":"1025000","totalValueInUsd":"12438.4","indian_port":"BOMBAY AIR","hs_no":"29372100","bill_no":"5925879","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"RUSSIA","selfForZScoreResived":"Sterile","supplierPort":"BOMBAY AIR","supplierAddress":"","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1672770600,"product":"HYDROCORTISONE SODIUM SUCCINATE FOR INJE","address":"385\/2, GRAM PIGDEMBER,,NEAR HOTEL MASHAL, RAU","city":"INDORE,MADHYA PRADESH","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES","customer":"TO THE ORDER","customerCountry":"ARGENTINA","quantity":"30.00","actualQuantity":"30","unit":"KGS","unitRateFc":"410","totalValueFC":"12072","currency":"USD","unitRateINR":32900,"date":"04-Jan-2023","totalValueINR":"987000","totalValueInUsd":"12072","indian_port":"BOMBAY AIR","hs_no":"29372900","bill_no":"6690832","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"385\/2, GRAM PIGDEMBER,,NEAR HOTEL MASHAL, RAU, INDORE,MADHYA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1673375400,"product":"HYDROCORTISONE ACETATE BP (MICRONISED)","address":"385\/2, GRAM PIGDEMBER,","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"KARACHI","customer":"GSK","customerCountry":"PAKISTAN","quantity":"20.00","actualQuantity":"20","unit":"KGS","unitRateFc":"495","totalValueFC":"9923.1","currency":"USD","unitRateINR":40565.25,"date":"11-Jan-2023","totalValueINR":"811305","totalValueInUsd":"9923.1","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372900","bill_no":"4000307","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Micronized","supplierPort":"Indore-EPZ\/SEZ","supplierAddress":"385\/2, GRAM PIGDEMBER,, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1675103400,"product":"HYDROCORTISONE SODIUM SUCCINATE FOR","address":"385\/2, GRAM PIGDEMBER,","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"GUARULHOS","customer":"ASHFORD INVEST & TRADE INC","customerCountry":"BRAZIL","quantity":"600.00","actualQuantity":"600","unit":"KGS","unitRateFc":"469.6","totalValueFC":"277587","currency":"USD","unitRateINR":37825.60833333333,"date":"31-Jan-2023","totalValueINR":"22695365","totalValueInUsd":"277587","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372900","bill_no":"4001366","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"Indore-EPZ\/SEZ","supplierAddress":"385\/2, GRAM PIGDEMBER,, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1676226600,"product":"HYDROCORTISONE ACETATE","address":"BG-533, SANJAY GANDHI TRANSPORT NAGAR","city":"DELHI","supplier":"DRUG CENTRE DELHI PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"BIRGUNJ","customer":"NOVA GENETICA","customerCountry":"NEPAL","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"34250","totalValueFC":"835.5","currency":"INR","unitRateINR":34500,"date":"13-Feb-2023","totalValueINR":"69000","totalValueInUsd":"835.5","indian_port":"RAXAUL","hs_no":"29372100","bill_no":"7737214","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"NEPAL","selfForZScoreResived":"Pharma Grade","supplierPort":"RAXAUL","supplierAddress":"BG-533, SANJAY GANDHI TRANSPORT NAGAR, DELHI","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1676572200,"product":"HYDROCORTISONE SODIUM SUCCINATE FOR INJE","address":"304, Town Centre, Andheri Kurla Road, Andheri East","city":"MUMBAI","supplier":"MAC-CHEM PRODUCTS (INDIA) PVT.LTD","supplierCountry":"INDIA","foreign_port":"LAHORE","customer":"BANK AL HABIB ","customerCountry":"PAKISTAN","quantity":"225.00","actualQuantity":"225","unit":"KGS","unitRateFc":"409","totalValueFC":"91258","currency":"USD","unitRateINR":33497.777777777781,"date":"17-Feb-2023","totalValueINR":"7537000","totalValueInUsd":"91258","indian_port":"BOMBAY AIR","hs_no":"29372100","bill_no":"7870474","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"304, Town Centre, Andheri Kurla Road, Andheri East, MUMBAI","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1677781800,"product":"HYDROCORTISONE SODIUM SUCCINATE FOR INJE","address":"PLOT NO.2516 & 2518, G.I.D.C. SARIGAM, TAL: UMBERGAON,","city":"DIST: VALSAD\/GUJARAT","supplier":"ARIHANTANAM LIFECARE PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"BANGKOK","customer":"ABLE MEDICAL COMPANY ","customerCountry":"THAILAND","quantity":"30.00","actualQuantity":"30","unit":"KGS","unitRateFc":"470","totalValueFC":"13896.6","currency":"USD","unitRateINR":38100,"date":"03-Mar-2023","totalValueINR":"1143000","totalValueInUsd":"13896.6","indian_port":"BOMBAY AIR","hs_no":"29379090","bill_no":"8218780","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"THAILAND","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"PLOT NO.2516 & 2518, G.I.D.C. SARIGAM, TAL: UMBERGAON,, DIST: VALSAD\/GUJARAT","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1682965800,"product":"HYDROCORTISONE EP (MICRONISED)","address":"385\/2, GRAM PIGDEMBER,","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES","customer":"LABORATORIO PABLO CASSARA ","customerCountry":"ARGENTINA","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"493.3","totalValueFC":"24400","currency":"USD","unitRateINR":40154.620000000003,"date":"02-May-2023","totalValueINR":"2007731","totalValueInUsd":"24400","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372900","bill_no":"4006275","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Micronized","supplierPort":"Indore-EPZ\/SEZ","supplierAddress":"385\/2, GRAM PIGDEMBER,, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1684348200,"product":"HYDROCORTISONE MICRONISED USP LOT EL2116 EK1306 EH3951 ETO STERILISATION AND RE EXPORT JOB WORK","address":"308-309, ATL CORPORATE PARK,,SAKI VIHAR ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"MICROTROL STERILISATION SERVICES PVT LTD","supplierCountry":"INDIA","foreign_port":"MADRID","customer":"PHARMALOOP S L","customerCountry":"SPAIN","quantity":"0.06","actualQuantity":"0.06","unit":"KGS","unitRateFc":"450","totalValueFC":"24.3","currency":"USD","unitRateINR":33333.333333333336,"date":"18-May-2023","totalValueINR":"2000","totalValueInUsd":"24.3","indian_port":"BANGALORE AIR","hs_no":"29372100","bill_no":"0","productDescription":"Re-export","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Micronized","supplierPort":"BANGALORE AIR","supplierAddress":"308-309, ATL CORPORATE PARK,,SAKI VIHAR ROAD,, MUMBAI,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1684693800,"product":"HYDROCORTISONE SODIUM SUCCINATE FOR INJECTION LYOPHILISED STERILE BULK","address":"304, Town Centre, Andheri Kurla Road, Andheri East","city":"MUMBAI","supplier":"MAC CHEM PRODUCTS INDIA PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"HANOI NOIBAI","customer":"VINH PHUC PHARMACEUTICAL ","customerCountry":"VIETNAM","quantity":"155.00","actualQuantity":"155","unit":"KGS","unitRateFc":"390","totalValueFC":"59890","currency":"USD","unitRateINR":31793.548387096773,"date":"22-May-2023","totalValueINR":"4928000","totalValueInUsd":"59890","indian_port":"BOMBAY AIR","hs_no":"29372100","bill_no":"0","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"VIETNAM","selfForZScoreResived":"Sterile","supplierPort":"BOMBAY AIR","supplierAddress":"304, Town Centre, Andheri Kurla Road, Andheri East, MUMBAI","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1685125800,"product":"HYDROCORTISONE EP (MICRONISED)","address":"385\/2, GRAM PIGDEMBER,","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"MARSEILLE","customer":"XXAVIXX EUXXPE XXBH","customerCountry":"FRANCE","quantity":"225.00","actualQuantity":"225","unit":"KGS","unitRateFc":"702","totalValueFC":"156548.6","currency":"USD","unitRateINR":57251.022222222222,"date":"27-May-2023","totalValueINR":"12881480","totalValueInUsd":"156548.6","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372100","bill_no":"4007711","productDescription":"API","marketType":"REGULATED MARKET","country":"FRANCE","selfForZScoreResived":"Micronized","supplierPort":"Indore-EPZ\/SEZ","supplierAddress":"385\/2, GRAM PIGDEMBER,, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1695407400,"product":"HYDROCORTISONE SODIUM SUCCINATE FOR INJECTION (LYOPHILISED STERILE BULK)","address":"304, TOWN CENTRE, ANDHERI KURLA","city":"MUMBAI \/ MAHARASHTRA","supplier":"MAC-CHEM PRODUCTS (INDIA) PVT.LTD","supplierCountry":"INDIA","foreign_port":"LAHORE","customer":"BANK AL HABIB ","customerCountry":"PAKISTAN","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"385","totalValueFC":"76203.7","currency":"USD","unitRateINR":31675,"date":"23-Sep-2023","totalValueINR":"6335000","totalValueInUsd":"76203.7","indian_port":"Bombay Air","hs_no":"29372100","bill_no":"4145038","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Sterile","supplierPort":"Bombay Air","supplierAddress":"304, TOWN CENTRE, ANDHERI KURLA, MUMBAI \/ MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1695580200,"product":"PHARMACEUTICALS APIS HYDROCORTISONE SODIUM SUCCINATE FOR INJECTION USP FOR MANUFACTURERS USE (HYDROCORTISONE SODIUM","address":"385\/2, GRAM PIGDEMBER,NEAR HOTEL MASHAL, RAU","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES","customer":"TO THE ORDER,","customerCountry":"ARGENTINA","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"450","totalValueFC":"4306.4","currency":"USD","unitRateINR":35800,"date":"25-Sep-2023","totalValueINR":"358000","totalValueInUsd":"4306.4","indian_port":"Bombay Air","hs_no":"29372900","bill_no":"4173903","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"385\/2, GRAM PIGDEMBER,NEAR HOTEL MASHAL, RAU, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1695666600,"product":"HYDROCORTISONE IP\/EP\/USP","address":"44-FAIZ-E-EDROOS,371-373","city":"MUMBAI ,MAHARASHTRA","supplier":"JAYANA PHARMA","supplierCountry":"INDIA","foreign_port":"BIRGUNJ","customer":"NEPAL PHARMACEUTICAL LAB ","customerCountry":"NEPAL","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"40000","totalValueFC":"2405.8","currency":"INR","unitRateINR":40000,"date":"26-Sep-2023","totalValueINR":"200000","totalValueInUsd":"2405.8","indian_port":"Raxaul","hs_no":"29372100","bill_no":"4191458","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"NEPAL","selfForZScoreResived":"Pharma Grade","supplierPort":"Raxaul","supplierAddress":"44-FAIZ-E-EDROOS,371-373, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1695753000,"product":"HYDROCORTISONE ACETATE","address":"BG-533, SANJAY GANDHI TRANSPORT","city":"DELHI","supplier":"DRUG CENTRE DELHI PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"BIRGUNJ","customer":"MARUTI PHARMA PVT.LTD","customerCountry":"NEPAL","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"34250","totalValueFC":"2057","currency":"INR","unitRateINR":34200,"date":"27-Sep-2023","totalValueINR":"171000","totalValueInUsd":"2057","indian_port":"Raxaul","hs_no":"29372100","bill_no":"4228993","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"NEPAL","selfForZScoreResived":"Pharma Grade","supplierPort":"Raxaul","supplierAddress":"BG-533, SANJAY GANDHI TRANSPORT, DELHI","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1698258600,"product":"HYDROCORTISONE SOD. SUCC. FOR INJ.(LYOPHILISED STERILE BULK)","address":"304, TOWN CENTRE, ANDHERI KURLA","city":"MUMBAI \/ MAHARASHTRA","supplier":"MAC-CHEM PRODUCTS (INDIA) PVT.LTD","supplierCountry":"INDIA","foreign_port":"JAKARTA","customer":"PT EUTHICA UNGGUL ","customerCountry":"INDONESIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"575","totalValueFC":"2822.6","currency":"USD","unitRateINR":47000,"date":"26-Oct-2023","totalValueINR":"235000","totalValueInUsd":"2822.6","indian_port":"Bombay Air","hs_no":"29372100","bill_no":"4903149","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"INDONESIA","selfForZScoreResived":"Sterile","supplierPort":"Bombay Air","supplierAddress":"304, TOWN CENTRE, ANDHERI KURLA, MUMBAI \/ MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1698690600,"product":"HYDROCORTISONE ACETATE UP","address":"502 B-WING CRYSTAL PLAZA,","city":"ANDHERI WEST, MUMBAI","supplier":"ORIENT PHARMA","supplierCountry":"INDIA","foreign_port":"BIRATNAGAR","customer":"ALIVE PHARMACETICALS PVT.LTD.","customerCountry":"NEPAL","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"35400","totalValueFC":"852.8","currency":"INR","unitRateINR":35500,"date":"31-Oct-2023","totalValueINR":"71000","totalValueInUsd":"852.8","indian_port":"Jogbani","hs_no":"29372100","bill_no":"5009357","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"NEPAL","selfForZScoreResived":"Pharma Grade","supplierPort":"Jogbani","supplierAddress":"502 B-WING CRYSTAL PLAZA,, ANDHERI WEST, MUMBAI","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1699468200,"product":"PHARMACEUTICALS APIS HYDROCORTISONE SODIUM SUCCINATE FOR INJECTION USP FOR MANUFACTURERS USE (HYDROCORTISONE SODIUM SU","address":"385\/2, GRAM PIGDEMBER,NEAR HOTEL MASHAL, RAU","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES","customer":"TO THE ORDER,","customerCountry":"ARGENTINA","quantity":"15.00","actualQuantity":"15","unit":"KGS","unitRateFc":"370","totalValueFC":"5382.8","currency":"USD","unitRateINR":29800,"date":"09-Nov-2023","totalValueINR":"447000","totalValueInUsd":"5382.8","indian_port":"Bombay Air","hs_no":"29372900","bill_no":"5262505","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"385\/2, GRAM PIGDEMBER,NEAR HOTEL MASHAL, RAU, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1701023400,"product":"HYDROCORTISONE ACETATE USP (MICRONISED)","address":"3, BOTAWALA BLDG., 1ST FLOOR,","city":"FORT, MUMBAI MAHARASHTRA","supplier":"NISHCHEM INTERNATIONAL PVT. LTD","supplierCountry":"INDIA","foreign_port":"BIRGUNJ","customer":"TO THE ORDER OF","customerCountry":"NEPAL","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"39000","totalValueFC":"939.3","currency":"INR","unitRateINR":39000,"date":"27-Nov-2023","totalValueINR":"78000","totalValueInUsd":"939.3","indian_port":"Raxaul","hs_no":"29372100","bill_no":"5606961","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"NEPAL","selfForZScoreResived":"Micronized","supplierPort":"Raxaul","supplierAddress":"3, BOTAWALA BLDG., 1ST FLOOR,, FORT, MUMBAI MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1701282600,"product":"PHARMACEUTICALS APIS HYDROCORTISONE HYDROGEN SUCCINATE BP\/PHEUR","address":"385\/2, GRAM PIGDEMBER,NEAR HOTEL MASHAL, RAU","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"YELGRAD (BEOGRAD)","customer":"TO THE ORDER","customerCountry":"SERBIA","quantity":"240.00","actualQuantity":"240","unit":"KGS","unitRateFc":"925","totalValueFC":"219031.9","currency":"USD","unitRateINR":75787.5,"date":"30-Nov-2023","totalValueINR":"18189000","totalValueInUsd":"219031.9","indian_port":"Bombay Air","hs_no":"29372900","bill_no":"5686245","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"SERBIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"385\/2, GRAM PIGDEMBER,NEAR HOTEL MASHAL, RAU, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1702233000,"product":"HYDROCORTISONE IP\/EP\/USP BATCH NO:TA0551,MFG DT:APR-23,EXP DT:APR-26","address":"205,B B C TOWER","city":"BARODA","supplier":"AKHIL HEALTHCARE PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"COLOMBO","customer":"THEIT WORLDWIDE FZE LLC","customerCountry":"SRI LANKA","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"700","totalValueFC":"1902.6","currency":"USD","unitRateINR":52666.666666666664,"date":"11-Dec-2023","totalValueINR":"158000","totalValueInUsd":"1902.6","indian_port":"JNPT","hs_no":"29372100","bill_no":"5942086","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"SRI LANKA","selfForZScoreResived":"Pharma Grade","supplierPort":"JNPT","supplierAddress":"205,B B C TOWER, BARODA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1704479400,"product":"RAW MATERIAL USE IN PHARMACEUTICAL INDUSTRIES HYDROCORTISONE ACETATE USP(AS PERINVOICE)","address":"814, `DEVPATH`, BESIDE LAL BUNGLOW,","city":"C.G.ROAD\/ AHMEDABD\/GUJARAT","supplier":"ESPEE PHARMA CHEM ","supplierCountry":"INDIA","foreign_port":"KABUL","customer":"TO ORDER","customerCountry":"AFGHANISTAN","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"460","totalValueFC":"870","currency":"USD","unitRateINR":36122.345000000001,"date":"06-Jan-2024","totalValueINR":"72244.69","totalValueInUsd":"870","indian_port":"Ahmedabad ICD","hs_no":"29372100","bill_no":"6572012","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"AFGHANISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Ahmedabad ICD","supplierAddress":"814, `DEVPATH`, BESIDE LAL BUNGLOW,, C.G.ROAD\/ AHMEDABD\/GUJARAT","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1705343400,"product":"HYDROCORTISONE SOD. SUCC. FOR INJ.(LYOPHILISED STERILE BULK)","address":"304, TOWN CENTRE, ANDHERI KURLA","city":"MUMBAI \/ MAHARASHTRA","supplier":"MAC-CHEM PRODUCTS (INDIA) PVT.LTD","supplierCountry":"INDIA","foreign_port":"JAKARTA","customer":"PT EUTHICA UNGGUL ","customerCountry":"INDONESIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"575","totalValueFC":"2740.7","currency":"USD","unitRateINR":45519.300000000003,"date":"16-Jan-2024","totalValueINR":"227596.5","totalValueInUsd":"2740.7","indian_port":"Bombay Air","hs_no":"29372100","bill_no":"6792035","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"INDONESIA","selfForZScoreResived":"Sterile","supplierPort":"Bombay Air","supplierAddress":"304, TOWN CENTRE, ANDHERI KURLA, MUMBAI \/ MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1711823400,"product":"RAW MATERIAL USE IN PHARMACEUTICAL INDUSTRIES HYDROCORTISONE ACETATE USP(AS PERINVOICE)","address":"814, `DEVPATH`, BESIDE LAL BUNGLOW,","city":"C.G.ROAD\/ AHMEDABD\/GUJARAT","supplier":"ESPEE PHARMA CHEM ","supplierCountry":"INDIA","foreign_port":"HERAT","customer":"TO ORDER","customerCountry":"AFGHANISTAN","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"503","totalValueFC":"996.4","currency":"USD","unitRateINR":41371.805,"date":"31-Mar-2024","totalValueINR":"82743.61","totalValueInUsd":"996.4","indian_port":"Ahmedabad ICD","hs_no":"29372100","bill_no":"8794212","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"AFGHANISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Ahmedabad ICD","supplierAddress":"814, `DEVPATH`, BESIDE LAL BUNGLOW,, C.G.ROAD\/ AHMEDABD\/GUJARAT","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1714069800,"product":"PHARMACEUTICALS APIS: HYDROCORTISONE SODIUM SUCCINATE FOR INJECTION USP FOR MANUFACTURER\\'S USE (HYDROCORTISON","address":"385\/2, GRAM PIGDEMBER,NEAR HOTEL MASHAL, RAU","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"ISLAMABAD - ISLAMABA","customer":"TO THE ORDER","customerCountry":"PAKISTAN","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"393","totalValueFC":"38560.2","currency":"USD","unitRateINR":32021.439999999999,"date":"26-Apr-2024","totalValueINR":"3202144","totalValueInUsd":"38560.2","indian_port":"Bombay Air","hs_no":"29372900","bill_no":"9436591","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"385\/2, GRAM PIGDEMBER,NEAR HOTEL MASHAL, RAU, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1714415400,"product":"HYDROCORTISONE SOD. SUCC. FOR INJ.(LYOPHILISED STERILE BULK)","address":"304, TOWN CENTRE, ANDHERI KURLA","city":"MUMBAI \/ MAHARASHTRA","supplier":"MAC-CHEM PRODUCTS (INDIA) PVT.LTD","supplierCountry":"INDIA","foreign_port":"JAKARTA","customer":"PT EUTHICA UNGGUL ","customerCountry":"INDONESIA","quantity":"15.00","actualQuantity":"15","unit":"KGS","unitRateFc":"575","totalValueFC":"8564.5","currency":"USD","unitRateINR":47414.666666666664,"date":"30-Apr-2024","totalValueINR":"711220","totalValueInUsd":"8564.5","indian_port":"Bombay Air","hs_no":"29372100","bill_no":"9534636","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"INDONESIA","selfForZScoreResived":"Sterile","supplierPort":"Bombay Air","supplierAddress":"304, TOWN CENTRE, ANDHERI KURLA, MUMBAI \/ MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1715797800,"product":"PHARMACEUTICAL RAW MATERIAL\/BULK DRUGS-HYDROCORTISONE BASE USP","address":"309 HARIKRUPA TOWER NR.OLD-","city":"AHMEDABAD","supplier":"JAI RADHE SALES","supplierCountry":"INDIA","foreign_port":"MONTEVIDEO -","customer":"TO THE ORDER OF","customerCountry":"URUGUAY","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"531","totalValueFC":"468.4","currency":"USD","unitRateINR":38893.620000000003,"date":"16-May-2024","totalValueINR":"38893.62","totalValueInUsd":"468.4","indian_port":"Ahmedabad Air","hs_no":"29372200","bill_no":"9913732","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"URUGAY","selfForZScoreResived":"Pharma Grade","supplierPort":"Ahmedabad Air","supplierAddress":"309 HARIKRUPA TOWER NR.OLD-, AHMEDABAD","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1715970600,"product":"RAW MATERIAL USE IN PHARMACEUTICAL INDUSTRIES HYDROCORTISONE ACETATE USP (AS PERINVOICE)","address":"814, `DEVPATH`, BESIDE LAL BUNGLOW,","city":"C.G.ROAD\/ AHMEDABD\/GUJARAT","supplier":"ESPEE PHARMA CHEM ","supplierCountry":"INDIA","foreign_port":"SALALAH","customer":"TO ORDER","customerCountry":"OMAN","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"420","totalValueFC":"2090.1","currency":"USD","unitRateINR":34713.014000000003,"date":"18-May-2024","totalValueINR":"173565.07","totalValueInUsd":"2090.1","indian_port":"Ahmedabad ICD","hs_no":"29372100","bill_no":"9995076","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"OMAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Ahmedabad ICD","supplierAddress":"814, `DEVPATH`, BESIDE LAL BUNGLOW,, C.G.ROAD\/ AHMEDABD\/GUJARAT","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1722191400,"product":"HYDROCORTISONE EP ( COUNTRY OF ORIGIN CHINA )","address":"301 - B, HERITAGE HOUSE, GUNDVALI","city":"MUMBAI,","supplier":"VERTEX CHEMICALS","supplierCountry":"INDIA","foreign_port":"COLOMBO","customer":"TO THE ORDER OF..,,.,","customerCountry":"SRI LANKA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"700","totalValueFC":"1410","currency":"USD","unitRateINR":58546.739999999998,"date":"29-Jul-2024","totalValueINR":"117093.48","totalValueInUsd":"1410","indian_port":"JNPT","hs_no":"29372100","bill_no":"2801096","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"SRI LANKA","selfForZScoreResived":"Pharma Grade","supplierPort":"JNPT","supplierAddress":"301 - B, HERITAGE HOUSE, GUNDVALI, MUMBAI,","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1723401000,"product":"HYDROCORTISONE ACETATE IP","address":"224 A BLOCK SEVENTH HEAVEN","city":"AHMEDABAD","supplier":"NASSIL MEDICARE","supplierCountry":"INDIA","foreign_port":"KATHMANDU","customer":"TO THE ORDER OF","customerCountry":"NEPAL","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"31500","totalValueFC":"1138","currency":"INR","unitRateINR":31500.00333333333,"date":"12-Aug-2024","totalValueINR":"94500.01","totalValueInUsd":"1138","indian_port":"Raxaul","hs_no":"29372100","bill_no":"3156378","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"NEPAL","selfForZScoreResived":"Pharma Grade","supplierPort":"Raxaul","supplierAddress":"224 A BLOCK SEVENTH HEAVEN, AHMEDABAD","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724783400,"product":"PHARMACEUTICALS APIS: HYDROCORTISONE SODIUM SUCCINATE USP (STERILE)","address":"385\/2, GRAM PIGDEMBER,NEAR HOTEL MASHAL, RAU","city":"INDORE, M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"CAIRO","customer":"TO THE ORDER","customerCountry":"EGYPT","quantity":"15.00","actualQuantity":"15","unit":"KGS","unitRateFc":"300","totalValueFC":"4311","currency":"USD","unitRateINR":23866.32,"date":"28-Aug-2024","totalValueINR":"357994.8","totalValueInUsd":"4311","indian_port":"Bombay Air","hs_no":"29372900","bill_no":"3535912","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"EGYPT","selfForZScoreResived":"Sterile","supplierPort":"Bombay Air","supplierAddress":"385\/2, GRAM PIGDEMBER,NEAR HOTEL MASHAL, RAU, INDORE, M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724869800,"product":"HYDROCORTISONE EP (MICRONISED)","address":"385\/2,GRAM PIGDEMBER,NEAR HOTEL MASHAL,RAU","city":"INDORE,M.P.","supplier":"SYMBIOTEC PHARMALAB","supplierCountry":"INDIA","foreign_port":"MARSEILLE","customer":"SPTT","customerCountry":"FRANCE","quantity":"33.00","actualQuantity":"33","unit":"KGS","unitRateFc":"750","totalValueFC":"24486.9","currency":"USD","unitRateINR":61619.909090909088,"date":"29-Aug-2024","totalValueINR":"2033457","totalValueInUsd":"24486.9","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372100","bill_no":"3583659","productDescription":"API","marketType":"REGULATED MARKET","country":"FRANCE","selfForZScoreResived":"Micronized","supplierPort":"Indore-EPZ\/SEZ","supplierAddress":"385\/2,GRAM PIGDEMBER,NEAR HOTEL MASHAL,RAU, INDORE,M.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724869800,"product":"HYDROCORTISONE ACETATE IP (MICRONISED)","address":"86,MAROL CO-OP. INDUSTRIAL ESTATE,","city":"MUMBAI","supplier":"UNI MED INDIA","supplierCountry":"INDIA","foreign_port":"PARAMARIBO","customer":"APERA NV","customerCountry":"SURINAME","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"396","totalValueFC":"596.4","currency":"USD","unitRateINR":24762.154999999999,"date":"29-Aug-2024","totalValueINR":"49524.31","totalValueInUsd":"596.4","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"3595485","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"SURINAME","selfForZScoreResived":"Micronized","supplierPort":"Bombay Air","supplierAddress":"86,MAROL CO-OP. INDUSTRIAL ESTATE,, MUMBAI","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1628188200,"product":"HYDROCORTISONE SODIUM PHOSPHATE","address":"MUMBAI CENTRAL,","city":"MUMBAI, MAHARASHTRA.","supplier":"CRYSTAL PHARMA S.A.U","supplierCountry":"SPAIN","foreign_port":"MADRID","customer":"CIPLA","customerCountry":"INDIA","quantity":"0.30","actualQuantity":"0.3","unit":"KGS","unitRateFc":"5000","totalValueFC":"1518.9","currency":"USD","unitRateINR":"375500","date":"06-Aug-2021","totalValueINR":"112650","totalValueInUsd":"1518.9","indian_port":"BOMBAY AIR","hs_no":"29372100","bill_no":"4959434","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"MADRID","supplierAddress":"","customerAddress":"MUMBAI CENTRAL,"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1631471400,"product":"HYDROCORTISONE SODIUM PHOSPHATE","address":"MUMBAI CENTRAL,","city":"MUMBAI, MAHARASHTRA.","supplier":"CRYSTAL PHARMA S.A.U","supplierCountry":"SPAIN","foreign_port":"#N\/A","customer":"CIPLA","customerCountry":"INDIA","quantity":"2.50","actualQuantity":"2.5","unit":"KGS","unitRateFc":"5000","totalValueFC":"12566.9","currency":"USD","unitRateINR":"369750","date":"13-Sep-2021","totalValueINR":"924375","totalValueInUsd":"12566.9","indian_port":"BOMBAY AIR","hs_no":"29372100","bill_no":"5425413","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"#N\/A","supplierAddress":"","customerAddress":"MUMBAI CENTRAL,"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1632508200,"product":"HYDROCORTISONE SODIUM PHOSPHATE","address":"MUMBAI CENTRAL,","city":"MUMBAI, MAHARASHTRA.","supplier":"CRYSTAL PHARMA S.A.U","supplierCountry":"SPAIN","foreign_port":"#N\/A","customer":"CIPLA","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"5000","totalValueFC":"5057.3","currency":"USD","unitRateINR":"372000","date":"25-Sep-2021","totalValueINR":"372000","totalValueInUsd":"5057.3","indian_port":"BOMBAY AIR","hs_no":"29372100","bill_no":"5587067","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"#N\/A","supplierAddress":"","customerAddress":"MUMBAI CENTRAL,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1641493800,"product":"HYDROCORTISONE","address":"385\/2, GRAM PIGDEMBER,","city":"INDORE, M.P.","supplier":"YUANCHI HONG KONG ","supplierCountry":"CHINA","foreign_port":"WUHAN","customer":"SYMBIOTEC PHARMALAB","customerCountry":"INDIA","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"312.9","totalValueFC":"159416.7","currency":"USD","unitRateINR":"23751","date":"07-Jan-2022","totalValueINR":"11875500","totalValueInUsd":"159416.7","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372900","bill_no":"1000117","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"WUHAN","supplierAddress":"N\/A","customerAddress":"385\/2, GRAM PIGDEMBER,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1646159400,"product":"HYDROCORTISONE SODIUM PHOSPHATE","address":"CIPLA HOUSE, PENINSULA BUSINESS,PA RK,GANPATRAO KADAM MARG,LOWER","city":"PAREL MUMBAI MAHARASHTRA,MAHARASHTR","supplier":"CURIA","supplierCountry":"SPAIN","foreign_port":"NA","customer":"CIPLA","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"5000","totalValueFC":"24944.4","currency":"USD","unitRateINR":"380250","date":"02-Mar-2022","totalValueINR":"1901250","totalValueInUsd":"24944.4","indian_port":"BOMBAY AIR","hs_no":"29372100","bill_no":"7702494","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"CIPLA HOUSE, PENINSULA BUSINESS,PA RK,GANPATRAO KADAM MARG,LOWER"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1673461800,"product":"HYDROCORTISONE","address":"502 JOLLY BHAVAN 2, 7 NEW MARINE, LINES CHURCHGATE MUMBAI","city":"MUMBAI,MAHARASHTRA","supplier":"HENAN LIHUA PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"NA","customer":"B.M. CHEMIE","customerCountry":"INDIA","quantity":"106.00","actualQuantity":"106","unit":"KGS","unitRateFc":"360.6","totalValueFC":"39127.1","currency":"USD","unitRateINR":"30179.4","date":"12-Jan-2023","totalValueINR":"3199014","totalValueInUsd":"39127.1","indian_port":"BOMBAY AIR","hs_no":"29372100","bill_no":"4151575","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"502 JOLLY BHAVAN 2, 7 NEW MARINE, LINES CHURCHGATE MUMBAI"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1690569000,"product":"HYDROCORTISONE BASE EP (NOT FOR MEDICINAL USE)","address":"PLOT NO. 25 \/ 1, PHASE-III, G.I.D.C. ESTATE, NARODA,","city":"AHMEDABAD","supplier":"KHONSU INTERNATIONAL CO. ","supplierCountry":"CHINA","foreign_port":"NA","customer":"NEXUS PHARMA CHEM ","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"275","totalValueFC":"27754.4","currency":"USD","unitRateINR":"22810.9","date":"29-Jul-2023","totalValueINR":"2281124.685","totalValueInUsd":"27754.4","indian_port":"AHMEDABAD AIR","hs_no":"29372100","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Non Pharma","supplierPort":"NA","supplierAddress":"","customerAddress":"PLOT NO. 25 \/ 1, PHASE-III, G.I.D.C. ESTATE, NARODA,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1695925800,"product":"HYDROCORTISONE SODIUM SUCCINATE BUFFERED STERILE I.P. (USE IN PHARMACEUTICALS MANUFACTURING OF DRY INJECTION)","address":"302, NARMADA BLOCK-5,POCKET D-6, V","city":"NEW DELHI,DELHI","supplier":"BIOFER","supplierCountry":"ITALY","foreign_port":"BOLOGNA","customer":"SKYMAP PHARMACEUTICALS PVT LTD","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"575","totalValueFC":"3017.9","currency":"USD","unitRateINR":"50177.9","date":"29-Sep-2023","totalValueINR":"250889.25","totalValueInUsd":"3017.9","indian_port":"Delhi Air","hs_no":"29372100","bill_no":"8075795","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Sterile","supplierPort":"BOLOGNA","supplierAddress":"VIA TOMMASO DA CAZZANIGA,9\/620121MILANO (MI) ITALY","customerAddress":"302, NARMADA BLOCK-5,POCKET D-6, V"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

Upgrade, download data, analyse, strategize, subscribe with us contact

Drugs in Development

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

FDF Dossiers

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

FDA Orange Book

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Europe

01

SANOFI SpA

France

CPhI Worldwide, Milan

Attending

Sanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

Contact Supplier

France

Virtual Booth

Digital Content

Regulatory Info :

Registration Country : Italy

Hydrocortisone

Brand Name : Flebocortid Richter

Dosage Form : Hydrocortisone 1G 1 Units Parenteral Use

Dosage Strength : 1 bottle EV 1 g + 1 ampoule solv 10 ml

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

Portfolio PDF

Product Web Link

02

Sanofi-aventis Norway (3)

France

CPhI Worldwide, Milan

Attending

Sanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

Contact Supplier

France

Virtual Booth

Digital Content

Regulatory Info :

Registration Country : Norway

Hydrocortisone

Brand Name : Proctosedyl

Dosage Form : Rectal Salve

Dosage Strength : (not entered)

Packaging : Tube

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Norway

Portfolio PDF

Product Web Link

03

Orion Corporation

Finland

BioProcess International

Not Confirmed

Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

Contact Supplier

Finland

Virtual Booth

Digital Content

Regulatory Info :

Registration Country : Sweden

hydrokortison

Brand Name : Hydrokortison Orion

Dosage Form : TABLETT

Dosage Strength : 10 MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Sweden

Portfolio PDF

Product Web Link

Denmark

BioProcess International

Not Confirmed

09

Pfizer AG

U.S.A

BioProcess International

Not Confirmed

10

SOLVAY PHARMA SpA

Country

BioProcess International

Not Confirmed

Only 10 entries up to this point, click to access all

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Canada

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Australia

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

South Africa

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Listed Dossiers

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

DRUG PRODUCT COMPOSITIONS

Do you need Business Intel? Ask us

DOSAGE - SUSPENSION/DROPS;OTIC - EQ 0.2% BASE...DOSAGE - SUSPENSION/DROPS;OTIC - EQ 0.2% BASE;1%

USFDA APPLICATION NUMBER - 20805

DOSAGE - CREAM;TOPICAL - 5%;1%

USFDA APPLICATION NUMBER - 22436

DOSAGE - CREAM;TOPICAL - 1%

USFDA APPLICATION NUMBER - 80693

DOSAGE - TABLET;ORAL - 10MG

USFDA APPLICATION NUMBER - 8697

DOSAGE - TABLET;ORAL - 20MG

USFDA APPLICATION NUMBER - 8697

DOSAGE - TABLET;ORAL - 5MG

USFDA APPLICATION NUMBER - 8697

Related Excipient Companies

Upload your portfolio for free, ask us

Excipients by Applications

Click here to find the perfect excipient manufacturers by their capabilities

Topical

Fillers, Diluents & Binders

Solubilizers

Thickeners and Stabilizers

Parenteral

Direct Compression

Coating Systems & Additives

Lubricants & Glidants

Disintegrants & Superdisintegrants

Granulation

Emulsifying Agents

Controlled & Modified Release

Surfactant & Foaming Agents

Co-Processed Excipients

Film Formers & Plasticizers

Taste Masking

Chewable & Orodispersible Aids

Rheology Modifiers

API Stability Enhancers

Coloring Agents

Soft Gelatin

Digital Content

Create Content with PharmaCompass, ask us

DATA COMPILATION #PharmaFlow

FDA’s June 2024 list of off-patent, off-exclusivity drugs sees rise in cancer, HIV treatments

This week PharmaCompass brings to you key highlights of the US Food and Drug Administration’s recently released June 2024 list of Off-Patent, Off-Exclusivity Drugs without an Approved Generic (OPOE list). The list is a crucial resource for promoting competition and affordability in the pharmaceutical industry. Updated biannually in December and June, the OPOE list serves as a transparent guide for drug manufacturers. Since December 2021, the FDA has enhanced its transparency efforts by providing separate lists for prescription (Rx) and over-the-counter (OTC) drugs approved under a New Drug Application (NDA). This initiative is a significant cog in the FDA’s broader strategy to encourage the development and submission of Abbreviated New Drug Applications (ANDAs). ANDAs are a streamlined pathway for generic drug development, offering a more cost-effective alternative to brand-name drugs. By highlighting drugs that lack generic competition on the OPOE list, FDA aims to incentivize manufacturers to develop generics, ultimately leading to greater affordability and access for patients. Access the Interactive Dashboard on FDA's June 2024 List of Off-Patent Drugs (Free Excel) ALS drugs, cancer, asthma, HIV treatments among new drugs added to OPOE list The December 2023 OPOE list had 23 new applications of branded drugs eligible for but without generic competition. The June list further added 21 new applications of drugs that had never appeared before. These include bendamustine hydrochloride (to treat chronic lymphocytic leukemia), fluticasone propionate (to treat asthma), maraviroc (to treat HIV-1 infection in patients two years of age and older weighing at least 10 kilograms), carbamazepine (to treat epilepsy and bipolar I disorder), and posaconazole (an antifungal agent indicated for Aspergillus and Candida infections). There are two other drugs on the list – edaravone and riluzole – to treat amyotrophic lateral sclerosis (ALS) or Lou Gehrig’s disease (a neurological disorder). Much like the June 2023 OPOE list, nearly one-third of the prescription drugs listed are injectables – 170 out of 499. There are 74 prescription entries for oral solid dosage forms (such as tablets, capsules and modified release forms). The June 2024 OPOE list has 57 OTC drugs, a tad shy of the 60 drugs in last year’s list. Among them are antihistamine drugs (used to treat allergies), cetirizine hydrochloride, nizatidine, famotidine, loratadine and anti-obesity medication orlistat. The list also had a newly listed drug, which is a combination of chlorpheniramine maleate, ibuprofen and pseudoephedrine hydrochloride for treating allergic sinusitis. Out of the 57 OTC drug products on the list, 18 are delivered as oral solid dosage forms. Access the Interactive Dashboard on FDA's June 2024 List of Off-Patent Drugs (Free Excel) Novartis blockbusters lose exclusivity, Lupin wins FDA nod for copycat of Neurocrine’s bestseller This year, several large-selling drugs from drugmakers like Eisai, AbbVie, Gilead, Sanofi, Fresenius Kabi and others are due to face their first generic or biosimilar challengers in the US market. “First generics” are given for a first-to-file ANDA, for which there is no previously-approved ANDA by the FDA for the drug product. The agency considers first generics to be important to public health and prioritizes review of these submissions. First generics are eligible for a 180-day exclusivity period. Three of Novartis’ drugs have lost exclusivity so far, this year. These include Promacta/Revolade (eltrombopag) used to treat thrombocytopenia (low platelet count). Promacta was approved in 2015 and saw sales of US$ 2.27 billion last year. Annora Pharma scored an FDA approval for eltrombopag’s first generic in April. Tasigna (nilotinib), the Swiss drugmaker’s oral treatment for Philadelphia chromosome-positive chronic myeloid leukemia (a kind of leukemia where patients have an abnormal chromosome in their blood cells called the Philadelphia chromosome), got its first generic in January, which was introduced by Apotex. Tasigna brought in sales of US$ 1.85 billion in 2023 and its sales are projected to plummet to US$ 79 million by 2029. Novartis’ Rydapt (midostaurin) for treating adult patients with newly diagnosed acute myeloid leukemia (AML) also lost exclusivity in April. Neurocrine Biosciences’ top-selling drug Ingrezza (valbenazine) was the first FDA-approved drug to treat tardive dyskinesia, a disorder that involves involuntary movements. It raked in US$ 1.84 billion in 2023, registering a year-on-year growth of 29 percent. In April, Lupin won FDA’s approval for the first generic of valbenazine capsules. Access the Interactive Dashboard on FDA's June 2024 List of Off-Patent Drugs (Free Excel) Our view The Biden administration has been pushing hard to lower the price of prescription drugs. It is one of President Joe Biden’s central campaign promises this year. However, lowering drug prices is a bipartisan issue in the US. So whether a republican or a democrat takes over the US administration, making medicines affordable should remain a priority. In 2023, generic drugs accounted for US$ 424 billion of the US$ 1.6 trillion global pharmaceutical market. A determined FDA that is proactively looking to approve generic drugs will no doubt help this segment grow even further.