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Chemistry

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Also known as: Barnidipine hcl, 104757-53-1, Mepirodipine hydrochloride, Barnidipine hydrochloride [jan], Barnidipine (hydrochloride), 7lz6r3aem1
Molecular Formula
C27H30ClN3O6
Molecular Weight
528.0  g/mol
InChI Key
XEMPUKIZUCIZEY-YSCHMLPRSA-N
FDA UNII
7LZ6R3AEM1

Barnidipine Hydrochloride
1 2D Structure

Barnidipine Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5-O-[(3S)-1-benzylpyrrolidin-3-yl] 3-O-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride
2.1.2 InChI
InChI=1S/C27H29N3O6.ClH/c1-17-23(26(31)35-3)25(20-10-7-11-21(14-20)30(33)34)24(18(2)28-17)27(32)36-22-12-13-29(16-22)15-19-8-5-4-6-9-19;/h4-11,14,22,25,28H,12-13,15-16H2,1-3H3;1H/t22-,25-;/m0./s1
2.1.3 InChI Key
XEMPUKIZUCIZEY-YSCHMLPRSA-N
2.1.4 Canonical SMILES
CC1=C(C(C(=C(N1)C)C(=O)OC2CCN(C2)CC3=CC=CC=C3)C4=CC(=CC=C4)[N+](=O)[O-])C(=O)OC.Cl
2.1.5 Isomeric SMILES
CC1=C([C@@H](C(=C(N1)C)C(=O)O[C@H]2CCN(C2)CC3=CC=CC=C3)C4=CC(=CC=C4)[N+](=O)[O-])C(=O)OC.Cl
2.2 Other Identifiers
2.2.1 UNII
7LZ6R3AEM1
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1-benzyl-3-pyrrolidinyl Methyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

2. Barnidipine

3. Cyress

4. Libradin

5. Mepirodipine

6. Mepirodipine Hydrobromide, (s,s)-isomer

7. Mepirodipine Hydrochloride, (r,r)-isomer

8. Mepirodipine Hydrochloride, (r,s)-isomer

9. Mepirodipine Hydrochloride, (s,r)-isomer

10. Mepirodipine Hydrochloride, (s,s)-isomer

11. Mepirodipine Malate, (s,s)-isomer

12. Mepirodipine Oxalate, (r,s)-isomer

13. Mepirodipine Oxalate, (s,s)-isomer

14. Mepirodipine, (r,r)-isomer

15. Mepirodipine, (r,s)-isomer

16. Mepirodipine, (s,r)-isomer

17. Ym 09730

18. Ym-09730

2.3.2 Depositor-Supplied Synonyms

1. Barnidipine Hcl

2. 104757-53-1

3. Mepirodipine Hydrochloride

4. Barnidipine Hydrochloride [jan]

5. Barnidipine (hydrochloride)

6. 7lz6r3aem1

7. Chembl2093893

8. 104757-53-1 (hcl)

9. Barnidipine Hydrochloride (jan)

10. (s)-3-((s)-1-benzylpyrrolidin-3-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Hydrochloride

11. 3-((s)-1-benzylpyrrolidin-3-yl) 5-methyl (s)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Hydrochloride

12. Unii-7lz6r3aem1

13. Cyress

14. Hypoca

15. Ym730

16. Hypoca (tn)

17. Ym-09730-5

18. Barnidipinehydrochloride

19. Ly198561

20. Ym09730-5

21. Ncgc00181772-01

22. Ym 09730-5

23. Dsstox_cid_28580

24. Dsstox_rid_82851

25. Dsstox_gsid_48654

26. Schembl347963

27. Chembl2356712

28. Dtxsid8048654

29. Chebi:31253

30. Bcp12810

31. Tox21_113010

32. Bdbm50226128

33. Eu-730

34. Mfcd00915772

35. Ym-730

36. Barnidipine Hydrochloride [mi]

37. Barnidipine Hydrochloride [mart.]

38. (s-(r*,r*))-methyl 1-(phenylmethyl)-3-pyrrolidinyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate

39. Barnidipine Hydrochloride [who-dd]

40. Hy-107322

41. Ly-198561

42. Cas-104757-53-1

43. Cs-0028139

44. D01104

45. 757b531

46. J-001245

47. Q27268545

48. (+)-(3's,4s)-1-benzyl-3-pyrrolidinyl Methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate Hydrochloride

49. 3,5-pyridinedicarboxylic Acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, Methyl 1-(phenylmethyl)-3-pyrrolidinyl Ester, Hydrochloride, (s-(r*,r*))-

50. 3,5-pyridinedicarboxylic Acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, Methyl 1-(phenylmethyl)-3-pyrrolidinyl Ester, Monohydrochloride, (s-(r*,r*))-

51. 5-o-[(3s)-1-benzylpyrrolidin-3-yl] 3-o-methyl (4s)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 528.0 g/mol
Molecular Formula C27H30ClN3O6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Exact Mass527.1823134 g/mol
Monoisotopic Mass527.1823134 g/mol
Topological Polar Surface Area114 Ų
Heavy Atom Count37
Formal Charge0
Complexity917
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Calcium Channel Blockers

A class of drugs that act by selective inhibition of calcium influx through cellular membranes. (See all compounds classified as Calcium Channel Blockers.)


ABOUT THIS PAGE

Barnidipine Hydrochloride Manufacturers

A Barnidipine Hydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Barnidipine Hydrochloride, including repackagers and relabelers. The FDA regulates Barnidipine Hydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Barnidipine Hydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Barnidipine Hydrochloride manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Barnidipine Hydrochloride Suppliers

A Barnidipine Hydrochloride supplier is an individual or a company that provides Barnidipine Hydrochloride active pharmaceutical ingredient (API) or Barnidipine Hydrochloride finished formulations upon request. The Barnidipine Hydrochloride suppliers may include Barnidipine Hydrochloride API manufacturers, exporters, distributors and traders.

click here to find a list of Barnidipine Hydrochloride suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Barnidipine Hydrochloride GMP

Barnidipine Hydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Barnidipine Hydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Barnidipine Hydrochloride GMP manufacturer or Barnidipine Hydrochloride GMP API supplier for your needs.

Barnidipine Hydrochloride CoA

A Barnidipine Hydrochloride CoA (Certificate of Analysis) is a formal document that attests to Barnidipine Hydrochloride's compliance with Barnidipine Hydrochloride specifications and serves as a tool for batch-level quality control.

Barnidipine Hydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Barnidipine Hydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Barnidipine Hydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Barnidipine Hydrochloride EP), Barnidipine Hydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Barnidipine Hydrochloride USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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