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Chemistry

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Also known as: 23642-66-2, Benfluorex hcl, Lipophoral, Balans, Benfluorex (hydrochloride), Mediaxal
Molecular Formula
C19H21ClF3NO2
Molecular Weight
387.8  g/mol
InChI Key
NLOALSPYZIIXEO-UHFFFAOYSA-N
FDA UNII
X7O165XZ00

Benfluorex
1 2D Structure

Benfluorex

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethyl benzoate;hydrochloride
2.1.2 InChI
InChI=1S/C19H20F3NO2.ClH/c1-14(12-15-6-5-9-17(13-15)19(20,21)22)23-10-11-25-18(24)16-7-3-2-4-8-16;/h2-9,13-14,23H,10-12H2,1H3;1H
2.1.3 InChI Key
NLOALSPYZIIXEO-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(CC1=CC(=CC=C1)C(F)(F)F)NCCOC(=O)C2=CC=CC=C2.Cl
2.2 Other Identifiers
2.2.1 UNII
X7O165XZ00
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1-(2-trifluoromethylphenyl)-2-(benzoyloxyethyl)aminopropane Hcl

2. 780 Se

3. Benfluorex

4. Benfluorex Hydrochloride, (+-)-isomer

5. Benfluorex Maleate

6. Benfluorex, Methanesulfonate Salt

7. Benfluramate

8. Jp 992

9. S 780

10. Se 780

2.3.2 Depositor-Supplied Synonyms

1. 23642-66-2

2. Benfluorex Hcl

3. Lipophoral

4. Balans

5. Benfluorex (hydrochloride)

6. Mediaxal

7. 2-((1-(3-(trifluoromethyl)phenyl)propan-2-yl)amino)ethyl Benzoate Hydrochloride

8. Jp-992 (hydrochloride)

9. X7o165xz00

10. Ncgc00094832-01

11. 2-(-methyl-3-(trifluoromethyl)phenethylamino)ethyl Benzoate Hydrochloride

12. Jp 992

13. 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]ethyl Benzoate Hydrochloride

14. 2-{(1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl}amino)ethyl Benzoate Hydrochloride

15. Dsstox_cid_25854

16. Dsstox_rid_81175

17. Dsstox_gsid_45854

18. 2-((alpha-methyl-m-(trifluoromethyl)phenethyl)amino)ethanol Benzoate (ester)

19. 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethyl Benzoate;hydrochloride

20. 2-((1-methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)ethyl Benzoate Hydrochloride

21. Ethanol, 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]-, 1-benzoate, Hydrochloride (1:1)

22. Sr-01000838831

23. Einecs 245-801-8

24. Unii-x7o165xz00

25. 2-((1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl)amino)ethyl Benzoate Hydrochloride

26. Mediator (tn)

27. Ethanol, 2-((1-methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)-, 1-benzoate, Hydrochloride (1:1)

28. Prestwick_911

29. Einecs 245-020-2

30. 2-(alpha-methyl-3-(trifluoromethyl)phenylethylamino)ethyl Benzoat

31. Cas-23642-66-2

32. Mls002153789

33. Schembl467300

34. Spectrum1500669

35. Chembl1412305

36. Dtxsid8045854

37. Hms1569i15

38. Hms1921a14

39. Pharmakon1600-01500669

40. Amy33324

41. Hy-b1058

42. Tox21_111343

43. Benfluorex Hydrochloride [mi]

44. Ccg-39155

45. Mfcd00058493

46. Nsc757396

47. Akos015994754

48. Tox21_111343_1

49. Cs-4580

50. Ss-4205

51. (1)-2-((1-methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)ethyl Benzoate Hydrochloride

52. Benfluorex Hydrochloride [mart.]

53. Ethanol, 2-((alpha-methyl-m-(trifluoromethyl)phenethyl)amino)-, Benzoate (ester), Hcl

54. Benfluorex Hydrochloride [who-dd]

55. Ncgc00094832-02

56. Ncgc00178369-05

57. Ethanol, 2-((1-methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)-, Benzoate (ester), Hydrochloride

58. Smr001233170

59. Db-046210

60. Benfluorex Hydrochloride, Analytical Standard

61. Ft-0602882

62. Benfluorex Hydrochloride [ep Impurity]

63. D07508

64. D86322

65. Sr-01000838831-3

66. Sr-01000838831-4

67. W-110575

68. Q27293648

69. 2-({1-[3-(trifluoromethyl)phenyl]prop-2-yl}amino)ethylbenzoate Hydrochloride

70. 2-(1-(3-(trifluoromethyl)phenyl)propan-2-ylamino)ethyl Benzoate Hydrochloride

71. 2-(alpha-methyl-3-(trifluoromethyl)phenylethylamino)ethyl Benzoate Hydrochloride

72. 2-{(1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl}amino)ethylbenzoate Hydrochloride

2.4 Create Date
2005-07-19
3 Chemical and Physical Properties
Molecular Weight 387.8 g/mol
Molecular Formula C19H21ClF3NO2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count8
Exact Mass387.1212911 g/mol
Monoisotopic Mass387.1212911 g/mol
Topological Polar Surface Area38.3 Ų
Heavy Atom Count26
Formal Charge0
Complexity408
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Appetite Depressants

Agents that are used to suppress appetite. (See all compounds classified as Appetite Depressants.)


Hypolipidemic Agents

Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS. (See all compounds classified as Hypolipidemic Agents.)


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ABOUT THIS PAGE

Benfluorex Manufacturers

A Benfluorex manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Benfluorex, including repackagers and relabelers. The FDA regulates Benfluorex manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Benfluorex API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Benfluorex Suppliers

A Benfluorex supplier is an individual or a company that provides Benfluorex active pharmaceutical ingredient (API) or Benfluorex finished formulations upon request. The Benfluorex suppliers may include Benfluorex API manufacturers, exporters, distributors and traders.

click here to find a list of Benfluorex suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Benfluorex CEP

A Benfluorex CEP of the European Pharmacopoeia monograph is often referred to as a Benfluorex Certificate of Suitability (COS). The purpose of a Benfluorex CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Benfluorex EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Benfluorex to their clients by showing that a Benfluorex CEP has been issued for it. The manufacturer submits a Benfluorex CEP (COS) as part of the market authorization procedure, and it takes on the role of a Benfluorex CEP holder for the record. Additionally, the data presented in the Benfluorex CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Benfluorex DMF.

A Benfluorex CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Benfluorex CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Benfluorex suppliers with CEP (COS) on PharmaCompass.

Benfluorex GMP

Benfluorex Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Benfluorex GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Benfluorex GMP manufacturer or Benfluorex GMP API supplier for your needs.

Benfluorex CoA

A Benfluorex CoA (Certificate of Analysis) is a formal document that attests to Benfluorex's compliance with Benfluorex specifications and serves as a tool for batch-level quality control.

Benfluorex CoA mostly includes findings from lab analyses of a specific batch. For each Benfluorex CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Benfluorex may be tested according to a variety of international standards, such as European Pharmacopoeia (Benfluorex EP), Benfluorex JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Benfluorex USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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