Find Benproperine manufacturers, exporters & distributors on PharmaCompass

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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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JDMF

JDMFs Filed

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

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$ 0

MARKET PLACE

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API

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FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

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FDA Orange Book

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Europe

Europe

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Canada

Canada

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Australia

Australia

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South Africa

South Africa

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Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

PATENTS & EXCLUSIVITIES

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US Patents

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Data Compilation #PharmaFlow

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Chemistry

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Also known as: 2156-27-6, Cofrel, Benproperine [inn], 1-(2-(2-benzylphenoxy)-1-methylethyl)piperidine, 3aa6iz48yk, 1-[1-(2-benzylphenoxy)propan-2-yl]piperidine
Molecular Formula
C21H27NO
Molecular Weight
309.4  g/mol
InChI Key
JTUQXGZRVLWBCR-UHFFFAOYSA-N
FDA UNII
3AA6IZ48YK

Benproperine
1 2D Structure

Benproperine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-[1-(2-benzylphenoxy)propan-2-yl]piperidine
2.1.2 InChI
InChI=1S/C21H27NO/c1-18(22-14-8-3-9-15-22)17-23-21-13-7-6-12-20(21)16-19-10-4-2-5-11-19/h2,4-7,10-13,18H,3,8-9,14-17H2,1H3
2.1.3 InChI Key
JTUQXGZRVLWBCR-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(COC1=CC=CC=C1CC2=CC=CC=C2)N3CCCCC3
2.2 Other Identifiers
2.2.1 UNII
3AA6IZ48YK
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (+)-benproperine

2. (-)-benproperine

3. (r)-benproperine

4. (s)-benproperine

5. 1-((1r)-1-methyl-2-(2-(phenylmethyl)phenoxy)ethyl)-piperidine

6. 1-((1s)-1-methyl-2-(2-(phenylmethyl)phenoxy)ethyl)-piperidine

7. 1-(1-methyl-2-(2-(phenylmethyl)phenoxy)ethyl)-piperidine And 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylate) (2:1)

8. 1-(2-(2-benzylphenoxy)-1-methylethyl)piperidine

9. 1-(2-(2-benzylphenoxy)-1-methylethyl)piperidine Monophosphate

10. 1-(o-benzylphenoxy)-2-piperidinopropane Phosphate

11. Asa 158-5

12. Asa 158-5 Free Base

13. Asa-158-5

14. Asa-158-5 Free Base

15. Asa-1585 Pamoate

16. Benproperine Embonate

17. Benproperine Pamoate

18. Benproperine Phosphate

19. Benproperine Trihydrogen Phosphate

20. Benproperine, (+)-

21. Benproperine, (-)-

22. Benproperine, (r)-

23. Benproperine, (s)-

24. Cofrel

25. Piperidine, 1-((1r)-1-methyl-2-(2-(phenylmethyl)phenoxy)ethyl)-

26. Piperidine, 1-((1s)-1-methyl-2-(2-(phenylmethyl)phenoxy)ethyl)-

27. Pirexyl

28. Tussafug

2.3.2 Depositor-Supplied Synonyms

1. 2156-27-6

2. Cofrel

3. Benproperine [inn]

4. 1-(2-(2-benzylphenoxy)-1-methylethyl)piperidine

5. 3aa6iz48yk

6. 1-[1-(2-benzylphenoxy)propan-2-yl]piperidine

7. Benproperine (inn)

8. Asa 158/5 [as Phosphate]

9. Piperidine,1-[1-methyl-2-[2-(phenylmethyl)phenoxy]ethyl]-

10. 1-(1-(2-benzylphenoxy)propan-2-yl)piperidine

11. Benproperinum [inn-latin]

12. Bemproperina [inn-spanish]

13. Bemproperina

14. Benproperin

15. Benproperinum

16. Benproper-inum

17. Cofrel (tn)

18. Brn 1258822

19. Benproperine [mi]

20. Unii-3aa6iz48yk

21. Benproperine [mart.]

22. Benproperine [who-dd]

23. Schembl142207

24. Chembl2105910

25. Asa 158/5 Free Base

26. Asa-158/5 Free Base

27. Chebi:94380

28. 1-(2-(2-benzilfenossi)-1-metiletil)-piperidina [italian]

29. Dtxsid10862853

30. 1-(1-methyl-2-((alpha-phenyl-o-tolyl)oxy)ethyl)piperidine

31. Piperidine, 1-(1-methyl-2-(2-(phenylmethyl)phenoxy)ethyl)-

32. Piperidine, 1-(1-methyl-2-((alpha-phenyl-o-tolyl)oxy)ethyl)-

33. Akos015962139

34. Db13309

35. Mrf-0000197

36. Ac-15848

37. Ft-0707238

38. D07512

39. Ab00698314-05

40. 1-(2-(2-benzilfenossi)-1-metiletil)-piperidina

41. 5-20-02-00159 (beilstein Handbook Reference)

42. Q818139

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 309.4 g/mol
Molecular Formula C21H27NO
XLogP35.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count6
Exact Mass309.209264485 g/mol
Monoisotopic Mass309.209264485 g/mol
Topological Polar Surface Area12.5 Ų
Heavy Atom Count23
Formal Charge0
Complexity320
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 ATC Code

R - Respiratory system

R05 - Cough and cold preparations

R05D - Cough suppressants, excl. combinations with expectorants

R05DB - Other cough suppressants

R05DB02 - Benproperine


REF. STANDARDS & IMPURITIES

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ABOUT THIS PAGE

Benproperine Manufacturers

A Benproperine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Benproperine, including repackagers and relabelers. The FDA regulates Benproperine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Benproperine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Benproperine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Benproperine Suppliers

A Benproperine supplier is an individual or a company that provides Benproperine active pharmaceutical ingredient (API) or Benproperine finished formulations upon request. The Benproperine suppliers may include Benproperine API manufacturers, exporters, distributors and traders.

click here to find a list of Benproperine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Benproperine GMP

Benproperine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Benproperine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Benproperine GMP manufacturer or Benproperine GMP API supplier for your needs.

Benproperine CoA

A Benproperine CoA (Certificate of Analysis) is a formal document that attests to Benproperine's compliance with Benproperine specifications and serves as a tool for batch-level quality control.

Benproperine CoA mostly includes findings from lab analyses of a specific batch. For each Benproperine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Benproperine may be tested according to a variety of international standards, such as European Pharmacopoeia (Benproperine EP), Benproperine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Benproperine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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