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ACTIVE PHARMA INGREDIENTS

19 API Suppliers, 1 USDMF, 10 CEP/COS, 1 EU WC, 6 KDMF, 14 Listed Suppliers, $ API Reference Price

19 API Suppliers
1 USDMF
10 CEP/COS
1 EU WC
6 KDMF
14 Listed Suppliers
$ API Reference Price

INTERMEDIATES

8 Intermediates Suppliers

8 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

42 FDF Dossiers, 24 Europe, 2 South Africa, 16 Listed Dossiers

42 FDF Dossiers
24 Europe
2 South Africa
16 Listed Dossiers

DIGITAL CONTENT

1 NEWS #PharmaBuzz

media
1 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

21 Finished Drug Prices, 5 Annual Reports

globalSalesInformation
21 Finished Drug Prices
5 Annual Reports

MARKET PLACE

10 APIs, 1 FDF Dossiers

marketPlace
10 APIs
1 FDF Dossiers

REF. STANDARDS & IMPURITIES

4 EDQM

otherSolutions
4 EDQM

Fermion Benserazide HCl

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

API

FDF

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

2,030

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 14919-77-8, Benserazide hcl, 2-amino-3-hydroxy-n'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride, Benzerazide hydrochloride, Benserazide (hydrochloride), 2'-(2,3,4-trihydroxybenzyl)-dl-serinohydrazide monohydrochloride

Molecular Formula

C₁₀H₁₆ClN₃O₅

Molecular Weight

293.70 g/mol

InChI Key

ULFCBIUXQQYDEI-UHFFFAOYSA-N

FDA UNII

B66E5RK36Q

1 2D Structure

Benserazide Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide;hydrochloride

2.1.2 InChI

InChI=1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H

2.1.3 InChI Key

ULFCBIUXQQYDEI-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O.Cl

2.2 Other Identifiers

2.2.1 UNII

B66E5RK36Q

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. 14919-77-8

2. Benserazide Hcl

3. 2-amino-3-hydroxy-n'-(2,3,4-trihydroxybenzyl)propanehydrazide Hydrochloride

4. Benzerazide Hydrochloride

5. Benserazide (hydrochloride)

6. 2'-(2,3,4-trihydroxybenzyl)-dl-serinohydrazide Monohydrochloride

7. Ro 4-4602/001

8. Benserazide Hydrochloride [jan]

9. 14046-64-1

10. Dl-serine 2-(2,3,4-trihydroxybenzyl)hydrazine Hydrochloride

11. 2-amino-3-hydroxy-n'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide Hydrochloride

12. Mls000028424

13. B66e5rk36q

14. Dl-serine 2-(2,3,4-trihydroxybenzyl)hydrazide Hydrochloride

15. Chebi:31262

16. (s)-2-amino-3-hydroxy-n'-(2,3,4-trihydroxybenzyl)propanehydrazide Hydrochloride

17. 2-amino-3-hydroxy-n'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide;hydrochloride

18. Nsc-755907

19. Smr000058421

20. Ro-4-4602

21. Dsstox_cid_25412

22. Dsstox_rid_80862

23. Dsstox_gsid_45412

24. Benserazide (as Hydrochloride)

25. 3-hydroxy-1-oxo-1-[2-(2,3,4-trihydroxybenzyl)hydrazinyl]propan-2-aminium Chloride

26. Ccris 5092

27. Sr-01000003044

28. Einecs 238-991-9

29. Unii-b66e5rk36q

30. Mfcd00078571

31. Opera_id_1594

32. Ncgc00016709-01

33. Madopa (hoffmann-laroche)

34. Cas-14919-77-8

35. Mls001148252

36. Mls002222160

37. Schembl364720

38. Spectrum1500137

39. Chembl1255778

40. Dtxsid0045412

41. Hy-b0404a

42. Benserazide Hydrochloride (jp17)

43. Benserazide Hydrochloride - Bio-x

44. Hms1570l18

45. Hms1920g05

46. Pharmakon1600-01500137

47. Bcp14068

48. Cba17287

49. Tox21_110573

50. Tox21_500233

51. Ccg-38998

52. Nsc755907

53. S2453

54. Serine, 2-(2,3,4-trihydroxybenzyl)hydrazide, Monohydrochloride, Dl-

55. Benserazide Hydrochloride [mi]

56. Akos007930267

57. Dl-serine, 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide, Monohydrochloride

58. Tox21_110573_1

59. Ac-6825

60. H22b350

61. Lp00233

62. Nsc 755907

63. Sb44383

64. Benserazide Middot Hcl (ro 4-4602)

65. Benserazide Hydrochloride [mart.]

66. Ncgc00015163-09

67. Ncgc00093698-01

68. Ncgc00093698-02

69. Ncgc00093698-03

70. Ncgc00093698-04

71. Ncgc00093698-05

72. Ncgc00260918-01

73. As-13683

74. Bb166155

75. Benserazide Hydrochloride [who-dd]

76. B4108

77. Eu-0100233

78. Ft-0659734

79. Ft-0760799

80. Sw196391-3

81. B 7283

82. Benserazide Hydrochloride [ep Monograph]

83. D01653

84. D70746

85. Benserazide Hydrochloride, >=98% (tlc), Solid

86. A808862

87. Sr-01000003044-2

88. Sr-01000003044-8

89. W-108090

90. Q27114249

91. 2-amino-3-hydroxy-n'-(2,3,4-trihydroxybenzyl)propanehydrazidehydrochloride

92. Benserazide Hydrochloride, European Pharmacopoeia (ep) Reference Standard

93. Dl-serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide Hydrochloride

94. Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide, Hydrochloride (1:1)

95. 2-amino-3-hydroxy-n'-(2,3,4-trihydroxybenzyl)-propanehydrazide Hydrochloride

96. Benserazide For Peak Identification, European Pharmacopoeia (ep) Reference Standard

97. 2-amino-3-hydroxy-n'-(2,3,4-trihydroxybenzyl)-propanehydrazide Hydrochloride;benserazide Hcl

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₀H₁₆ClN₃O₅
Molecular Weight	293.70 g/mol
Hydrogen Bond Donor Count	8
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	5
Exact Mass	293.0778483 g/mol
Monoisotopic Mass	293.0778483 g/mol
Topological Polar Surface Area	148 Å²
Heavy Atom Count	19
Formal Charge	0
Complexity	278
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

API SUPPLIERS

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USDMF

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CEP/COS

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EU WC

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KDMF

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Listed Suppliers

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API Reference Price

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EUR. (TL NO: TL\/AZ\/22\/003466)FOR R&D PURPOSE NOT FOR SALE","address":"ZYDUS CORPORATE PARK, SCHEME NO 63, KHORAJ (GANDHINAGAR), NR. VAISHNODE","city":"AHMEDABAD","supplier":"ITALFARMACO S.P.A","supplierCountry":"ITALY","foreign_port":"NA","customer":"ZYDUS LIFESCIENCES","customerCountry":"INDIA","quantity":"0.50","actualQuantity":"0.5","unit":"KGS","unitRateFc":"1090","totalValueFC":"598","currency":"EUR","unitRateINR":"98372.5","date":"02-Mar-2023","totalValueINR":"49186.25","totalValueInUsd":"598","indian_port":"BOMBAY AIR","hs_no":"29280090","bill_no":"4875580","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"ZYDUS CORPORATE PARK, SCHEME NO 63, KHORAJ (GANDHINAGAR), NR. VAISHNODE"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1677695400,"product":"BENSERAZIDE HYDROCHLORIDE PH. EUR. (TL NO: TL\/WZ\/23\/000026)FOR R&D PURPOSE NOT FOR SALE","address":"ZYDUS CORPORATE PARK, SCHEME NO 63, KHORAJ (GANDHINAGAR), NR. VAISHNODE","city":"AHMEDABAD","supplier":"ITALFARMACO S.P.A","supplierCountry":"ITALY","foreign_port":"NA","customer":"ZYDUS LIFESCIENCES","customerCountry":"INDIA","quantity":"17.00","actualQuantity":"17","unit":"KGS","unitRateFc":"1090","totalValueFC":"20332.2","currency":"EUR","unitRateINR":"98372.5","date":"02-Mar-2023","totalValueINR":"1672332.5","totalValueInUsd":"20332.2","indian_port":"BOMBAY AIR","hs_no":"29280090","bill_no":"4875117","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"ZYDUS CORPORATE PARK, SCHEME NO 63, KHORAJ (GANDHINAGAR), NR. VAISHNODE"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1683570600,"product":"BENSERAZIDE HYDROCHLORIDE GOODS ARE FOR TESTING ANALYSIS AND DEVELOPMENT PURPOSE ONLY AND NOT FOR COMMERCIAL USE","address":"OFFICENO 5-6COMMERCE AVENUE PAUD R ,D","city":"PUNE","supplier":"BIOBETTA LIMITED","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"BATAVIA PHARMA PRIVATE ","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"1100","totalValueFC":"5521.1","currency":"USD","unitRateINR":"90860","date":"09-May-2023","totalValueINR":"454300","totalValueInUsd":"5521.1","indian_port":"BOMBAY AIR","hs_no":"29280090","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"China","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"","customerAddress":"OFFICENO 5-6COMMERCE AVENUE PAUD R ,D"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1686076200,"product":"BENSERAZIDE HYDROCHLORIDE","address":"MSN HOUSE, PLOT NO. C-24,INDUSTRIAL HYDERABAD","city":"HYDERABAD","supplier":"FERMION OY","supplierCountry":"FINLAND","foreign_port":"NA","customer":"MSN LABORATORIES","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"1500","totalValueFC":"7609.8","currency":"USD","unitRateINR":"125099.9","date":"07-Jun-2023","totalValueINR":"625499.7","totalValueInUsd":"7609.8","indian_port":"HYDERABAD AIR","hs_no":"29280090","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"FINLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"MSN HOUSE, PLOT NO. C-24,INDUSTRIAL HYDERABAD"}]