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CHEMISTRY
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ACTIVE PHARMA INGREDIENTS

18 API Suppliers, 1 USDMF, 10 CEP/COS, 1 EU WC, 6 KDMF, 13 Listed Suppliers, $ API Reference Price

18 API Suppliers
1 USDMF
10 CEP/COS
1 EU WC
6 KDMF
13 Listed Suppliers
$ API Reference Price

INTERMEDIATES

8 Intermediates Suppliers

8 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

42 FDF Dossiers, 24 Europe, 2 South Africa, 16 Listed Dossiers

42 FDF Dossiers
24 Europe
2 South Africa
16 Listed Dossiers

DIGITAL CONTENT

1 NEWS #PharmaBuzz

media
1 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

21 Finished Drug Prices, 5 Annual Reports

globalSalesInformation
21 Finished Drug Prices
5 Annual Reports

MARKET PLACE

10 APIs, 1 FDF Dossiers

marketPlace
10 APIs
1 FDF Dossiers

REF. STANDARDS & IMPURITIES

4 EDQM

otherSolutions
4 EDQM

Fermion Benserazide HCl

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

API

FDF

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

2,030

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 14919-77-8, Benserazide hcl, 2-amino-3-hydroxy-n'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride, Benzerazide hydrochloride, Benserazide (hydrochloride), 2'-(2,3,4-trihydroxybenzyl)-dl-serinohydrazide monohydrochloride

Molecular Formula

C₁₀H₁₆ClN₃O₅

Molecular Weight

293.70 g/mol

InChI Key

ULFCBIUXQQYDEI-UHFFFAOYSA-N

FDA UNII

B66E5RK36Q

1 2D Structure

Benserazide Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide;hydrochloride

2.1.2 InChI

InChI=1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H

2.1.3 InChI Key

ULFCBIUXQQYDEI-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O.Cl

2.2 Other Identifiers

2.2.1 UNII

B66E5RK36Q

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. 14919-77-8

2. Benserazide Hcl

3. 2-amino-3-hydroxy-n'-(2,3,4-trihydroxybenzyl)propanehydrazide Hydrochloride

4. Benzerazide Hydrochloride

5. Benserazide (hydrochloride)

6. 2'-(2,3,4-trihydroxybenzyl)-dl-serinohydrazide Monohydrochloride

7. Ro 4-4602/001

8. Benserazide Hydrochloride [jan]

9. 14046-64-1

10. Dl-serine 2-(2,3,4-trihydroxybenzyl)hydrazine Hydrochloride

11. 2-amino-3-hydroxy-n'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide Hydrochloride

12. Mls000028424

13. B66e5rk36q

14. Dl-serine 2-(2,3,4-trihydroxybenzyl)hydrazide Hydrochloride

15. Chebi:31262

16. (s)-2-amino-3-hydroxy-n'-(2,3,4-trihydroxybenzyl)propanehydrazide Hydrochloride

17. 2-amino-3-hydroxy-n'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide;hydrochloride

18. Nsc-755907

19. Smr000058421

20. Ro-4-4602

21. Dsstox_cid_25412

22. Dsstox_rid_80862

23. Dsstox_gsid_45412

24. Benserazide (as Hydrochloride)

25. 3-hydroxy-1-oxo-1-[2-(2,3,4-trihydroxybenzyl)hydrazinyl]propan-2-aminium Chloride

26. Ccris 5092

27. Sr-01000003044

28. Einecs 238-991-9

29. Unii-b66e5rk36q

30. Mfcd00078571

31. Opera_id_1594

32. Ncgc00016709-01

33. Madopa (hoffmann-laroche)

34. Cas-14919-77-8

35. Mls001148252

36. Mls002222160

37. Schembl364720

38. Spectrum1500137

39. Chembl1255778

40. Dtxsid0045412

41. Hy-b0404a

42. Benserazide Hydrochloride (jp17)

43. Benserazide Hydrochloride - Bio-x

44. Hms1570l18

45. Hms1920g05

46. Pharmakon1600-01500137

47. Bcp14068

48. Cba17287

49. Tox21_110573

50. Tox21_500233

51. Ccg-38998

52. Nsc755907

53. S2453

54. Serine, 2-(2,3,4-trihydroxybenzyl)hydrazide, Monohydrochloride, Dl-

55. Benserazide Hydrochloride [mi]

56. Akos007930267

57. Dl-serine, 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide, Monohydrochloride

58. Tox21_110573_1

59. Ac-6825

60. H22b350

61. Lp00233

62. Nsc 755907

63. Sb44383

64. Benserazide Middot Hcl (ro 4-4602)

65. Benserazide Hydrochloride [mart.]

66. Ncgc00015163-09

67. Ncgc00093698-01

68. Ncgc00093698-02

69. Ncgc00093698-03

70. Ncgc00093698-04

71. Ncgc00093698-05

72. Ncgc00260918-01

73. As-13683

74. Bb166155

75. Benserazide Hydrochloride [who-dd]

76. B4108

77. Eu-0100233

78. Ft-0659734

79. Ft-0760799

80. Sw196391-3

81. B 7283

82. Benserazide Hydrochloride [ep Monograph]

83. D01653

84. D70746

85. Benserazide Hydrochloride, >=98% (tlc), Solid

86. A808862

87. Sr-01000003044-2

88. Sr-01000003044-8

89. W-108090

90. Q27114249

91. 2-amino-3-hydroxy-n'-(2,3,4-trihydroxybenzyl)propanehydrazidehydrochloride

92. Benserazide Hydrochloride, European Pharmacopoeia (ep) Reference Standard

93. Dl-serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide Hydrochloride

94. Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide, Hydrochloride (1:1)

95. 2-amino-3-hydroxy-n'-(2,3,4-trihydroxybenzyl)-propanehydrazide Hydrochloride

96. Benserazide For Peak Identification, European Pharmacopoeia (ep) Reference Standard

97. 2-amino-3-hydroxy-n'-(2,3,4-trihydroxybenzyl)-propanehydrazide Hydrochloride;benserazide Hcl

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₀H₁₆ClN₃O₅
Molecular Weight	293.70 g/mol
Hydrogen Bond Donor Count	8
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	5
Exact Mass	293.0778483 g/mol
Monoisotopic Mass	293.0778483 g/mol
Topological Polar Surface Area	148 Å²
Heavy Atom Count	19
Formal Charge	0
Complexity	278
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

API SUPPLIERS

01

Fermion Oy

Finland

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

With Fermion, start the journey of your innovative API.

Contact Supplier

Finland

Virtual Booth

Digital Content

USDMF CEP/COS

JDMF EU-WC NDC KDMF

VMF Others AUDIT

02

Zhejiang Hengkang Pharmaceutical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI China

Attending

Zhejiang Hengkang Pharm Group is a dynamic pharmaceutical entity, spanning drug research, large-scale production, and global marketing.

Contact Supplier

China

Virtual Booth

Digital Content

USDMF CEP/COS

JDMF EU-WC NDC KDMF VMF Others AUDIT

03

Inke S.A

Spain

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

Inke S.A: APIs manufacturing plant.

Contact Supplier

Spain

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

04

Cohance Lifesciences

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

Cohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

Contact Supplier

India

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

05

Lifecare Laboratories Pvt Ltd

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

Lifecare Labs has been developing innovative products in specialist areas of medicine.

Contact Supplier

India

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

06

SCI Pharmtech

Taiwan

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

SCI Pharmtech offers high-quality, cost-effective APIs, advanced intermediates, & custom products with global expertise and precision.

Contact Supplier

Taiwan

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

07

Fermion Oy

Finland

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

With Fermion, start the journey of your innovative API.

Contact Supplier

Finland

Virtual Booth

Digital Content

USDMF CEP/COS

JDMF EU-WC NDC KDMF

VMF Others AUDIT

08

Zhejiang Hengkang Pharmaceutical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI China

Attending

Zhejiang Hengkang Pharm Group is a dynamic pharmaceutical entity, spanning drug research, large-scale production, and global marketing.

Contact Supplier

China

Virtual Booth

Digital Content

USDMF CEP/COS

JDMF EU-WC

NDC KDMF VMF Others AUDIT

09

SP QUIMICA, S.A.

Spain

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

10

Deva Holding AS

Turkey

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

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API Reference Price

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C-24,INDUSTRIAL HYDERABAD","city":"HYDERABAD","supplier":"FERMION OY","supplierCountry":"FINLAND","foreign_port":"NA","customer":"MSN LABORATORIES","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"1500","totalValueFC":"7609.8","currency":"USD","unitRateINR":"125099.9","date":"07-Jun-2023","totalValueINR":"625499.7","totalValueInUsd":"7609.8","indian_port":"HYDERABAD AIR","hs_no":"29280090","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"FINLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"MSN HOUSE, PLOT NO. C-24,INDUSTRIAL HYDERABAD"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1691778600,"product":"BENSERAZIDE HYDROCHLORIDE","address":"304 SAMAAN-II, OPP. SHELL PETROL, PUMP, NR.PRAHLAD NAGAR, SATELLITE","city":"AHMEDABAD","supplier":"SINOPHARM","supplierCountry":"CHINA","foreign_port":"NA","customer":"SWISS PARENTERALS LIMITED","customerCountry":"INDIA","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"940","totalValueFC":"9467.7","currency":"USD","unitRateINR":"77642.6","date":"12-Aug-2023","totalValueINR":"784268.32","totalValueInUsd":"9467.7","indian_port":"AHEMDABAD AIR","hs_no":"29280090","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"304 SAMAAN-II, OPP. 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