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Chemistry

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Also known as: Benclay, Bentolite l, Bentone 34, Aquagel, Askangel, Magbond
Molecular Formula
Al2H2O6Si
Molecular Weight
180.06  g/mol
InChI Key
SVPXDRXYRYOSEX-UHFFFAOYSA-N

Bentonite
Bentoquatam is a topical medication intended to act as a shield against exposure to the irritating substance urushiol, found in plants such as poison ivy or poison oak. Bentoquatam contains bentonite, a clay, and is only effective as long as the film is visible on the skin.
1 2D Structure

Bentonite

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
dioxosilane;oxo(oxoalumanyloxy)alumane;hydrate
2.1.2 InChI
InChI=1S/2Al.O2Si.H2O.3O/c;;1-3-2;;;;/h;;;1H2;;;
2.1.3 InChI Key
SVPXDRXYRYOSEX-UHFFFAOYSA-N
2.1.4 Canonical SMILES
O.O=[Al]O[Al]=O.O=[Si]=O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Bentone 34

2. Dimethyldioctadecylammonium Montmorillonite

3. Ivy Block

4. Quaternium 18-bentonite

2.2.2 Depositor-Supplied Synonyms

1. Benclay

2. Bentolite L

3. Bentone 34

4. Aquagel

5. Askangel

6. Magbond

7. Otaylite

8. Tixoton

9. Volclay

10. Wilkinite

11. Bengel

12. Culvin

13. Filgel

14. Akajo

15. Asama

16. Bentogrout

17. Soap Clay

18. Bentonit T

19. Bentolite Hs

20. Bulgarben Ba

21. Accugel F

22. Altonit Sf

23. Bengel A

24. Bengel Fw

25. Southern Bentonite

26. Bengel Hvp

27. Bentosolon 82

28. Aquagel Gold Seal

29. Detercal G 1fc

30. Detercal G 2fc

31. Detercol P 2

32. Bentone 27

33. Accofloc 352

34. Cosintam 403

35. Hi-jel

36. Bengel 11

37. Bengel 15

38. Bengel 23

39. Bentonite 2073

40. Bentone 660

41. Cvis

42. Fulbent 570

43. Volcaly Bentonite Bc

44. Aluminosilicate Hydrate

45. Imvite I.g.b.a

46. Bentonite [jan:nf]

47. Bentonite, Sodium Form

48. Panther Creek Bentonite

49. Clarit Bw 100

50. Clarit Bw 125

51. Black Hills Bh 200

52. Bentonite, Calcian-sodian

53. Unii-a3n5zcn45c

54. G 100 (clay)

55. Ex 0030 (clay)

56. Albagel Premium Usp 4444

57. Ccris 3663

58. Hsdb 392

59. Gk 129sa3

60. Gk 129sa5

61. Aeg 325

62. Ex-m 703

63. Einecs 215-108-5

64. Mfcd00130611

65. Ex 0276

66. 250m

67. Dioxosilane;oxo(oxoalumanyloxy)alumane;hydrate

68. Q20817027

2.3 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 180.06 g/mol
Molecular Formula Al2H2O6Si
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count0
Exact Mass179.925141 g/mol
Monoisotopic Mass179.925141 g/mol
Topological Polar Surface Area78.5 Ų
Heavy Atom Count9
Formal Charge0
Complexity52.4
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameIvy block
Active IngredientBentoquatam
Dosage FormLotion
RouteTopical
Strength5%
Market StatusOver the Counter
CompanyStand Homeopath

2 of 2  
Drug NameIvy block
Active IngredientBentoquatam
Dosage FormLotion
RouteTopical
Strength5%
Market StatusOver the Counter
CompanyStand Homeopath

4.2 Drug Indication

Used to prevent or reduce the severity of allergic contact dermatitis due to urushiol, the allergenic resin of poison ivy, poison oak, and poison sumac.


5 Pharmacology and Biochemistry
5.1 Pharmacology

Bentoquatam protects the skin like a shield against poison ivy, poison oak, and poison sumac by physically blocking skin contact with their resin. The best protection against getting these conditions is to avoid contact with these plants. This medicine does not dry oozing and weeping caused by the rash of poison ivy, poison oak, or poison sumac.


5.2 MeSH Pharmacological Classification

Dermatologic Agents

Drugs used to treat or prevent skin disorders or for the routine care of skin. (See all compounds classified as Dermatologic Agents.)


5.3 Mechanism of Action

The mechanism of action is unknown. It is thought topically applied bentoquatam acts as a physical barrier that interferes with the adsorption of antigens onto the skin and reduces absorption of antigens into the skin. It probably does not work by modifying the systemic allergic response.


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ABOUT THIS PAGE

Bentonite Manufacturers

A Bentonite manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Bentonite, including repackagers and relabelers. The FDA regulates Bentonite manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Bentonite API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Bentonite Suppliers

A Bentonite supplier is an individual or a company that provides Bentonite active pharmaceutical ingredient (API) or Bentonite finished formulations upon request. The Bentonite suppliers may include Bentonite API manufacturers, exporters, distributors and traders.

Bentonite GMP

Bentonite Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Bentonite GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Bentonite GMP manufacturer or Bentonite GMP API supplier for your needs.

Bentonite CoA

A Bentonite CoA (Certificate of Analysis) is a formal document that attests to Bentonite's compliance with Bentonite specifications and serves as a tool for batch-level quality control.

Bentonite CoA mostly includes findings from lab analyses of a specific batch. For each Bentonite CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Bentonite may be tested according to a variety of international standards, such as European Pharmacopoeia (Bentonite EP), Bentonite JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Bentonite USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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