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1. Benzimidazole Monohydrochloride
2. Benzimidazole Mononitrate
1. 1h-benzimidazole
2. 51-17-2
3. 1h-benzo[d]imidazole
4. 1,3-benzodiazole
5. Benzoimidazole
6. O-benzimidazole
7. 3-azaindole
8. Benziminazole
9. Benzoglyoxaline
10. Azindole
11. 1h-benzoimidazole
12. 1,3-diazaindene
13. Benzimidazol
14. N,n'-methenyl-o-phenylenediamine
15. Nsc 759
16. 1h-1,3-benzodiazole
17. Bzi
18. Chebi:41275
19. Nsc-759
20. Mfcd00005585
21. 1h-benzimidazole, Homopolymer
22. E24gx49ld8
23. 26985-65-9
24. Dsstox_cid_4573
25. Benzimidazole Phase Betaetha
26. Benzimidazole Phase Alphalpha
27. Benzimidazole Phase Gammaamma
28. Dsstox_rid_77454
29. Dsstox_gsid_24573
30. Cas-51-17-2
31. Ccris 5967
32. Hsdb 2797
33. Einecs 200-081-4
34. Bezimidazole
35. Brn 0109682
36. Unii-e24gx49ld8
37. Benz-imidazole
38. Hbzim
39. Hbim
40. Ai3-03737
41. 1h-benzimidazol
42. 4dsu
43. Benzimidazole, 98%
44. 1,3-benzodiazole, Bzi
45. Benzimidazole [mi]
46. Epitope Id:140095
47. Schembl6009
48. Schembl6010
49. Benzimidazole [hsdb]
50. Benzimidazole [inci]
51. Wln: T56 Bm Dnj
52. 5-23-06-00196 (beilstein Handbook Reference)
53. Mls001066336
54. Bdbm7939
55. Chembl306226
56. F3366-5347
57. Nsc759
58. Schembl5197771
59. Dtxsid8024573
60. Hms2233d03
61. Hms3370l16
62. Zinc331902
63. Hy-y1825
64. Tox21_202107
65. Tox21_303321
66. Stk397462
67. Akos000119163
68. Am81999
69. Cs-w019944
70. Db02962
71. Ps-5765
72. Ncgc00091255-01
73. Ncgc00091255-02
74. Ncgc00257173-01
75. Ncgc00259656-01
76. ((non-isotopelabelled)benzimidazole-13c6
77. Smr000471839
78. Sy012765
79. Db-002016
80. B0054
81. Ft-0606545
82. C02009
83. D70829
84. Q415190
85. W-105914
| Molecular Weight | 118.14 g/mol |
|---|---|
| Molecular Formula | C7H6N2 |
| XLogP3 | 1.3 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 0 |
| Exact Mass | 118.053098200 g/mol |
| Monoisotopic Mass | 118.053098200 g/mol |
| Topological Polar Surface Area | 28.7 Ų |
| Heavy Atom Count | 9 |
| Formal Charge | 0 |
| Complexity | 103 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Anthelmintics
Agents that kill parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal. (See all compounds classified as Anthelmintics.)
Benzimidazoles have only limited solubility in water; consequently, minor differences in solubility tend to have a major effect on absorption. Thiabenzole is rapidly absorbed after oral ingestion ... Most of the drug is excreted in the urine ... as 5-hydroxythiabendazole ... . In contrast tablet forms of mebendazole are poorly and erratically absorbed ... And is extensively metabolized. ... Like mebendazole, albendazole is variably and erratically absorbed after oral administration, although its absorbtion may be increased when it is given with a fatty meal.
Hardman, J.G., L.E. Limbird, P.B. Molinoff, R.W. Ruddon, A.G. Goodman (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill, 1996., p. 1013
5-HYDROXYBENZIMIDAZOLE IS A MAJOR URINARY METABOLITE OF BENZIMIDAZOLE IN RAT.
TYLER TR ET AL; DRUG METAB DISPOS 4(2) 177-9 (1976)
SIXTY DAYS AFTER TREATMENT WITH BENZIMIDAZOLE, MELON PLANTS CONTAINED METABOLITES 2-AMINOBENZONITRILE, O-PHENYLENEDIAMINE, ANILINE
ROUCHAUD JP ET AL; PESTIC SCI 8(1) 31-4 (1977)
Thiabendazole ... Is excreted in the urine as 5-hydroxythiabendazole, conjugated either as the glucuronide or as the sulfate. /Benzimidazoles/
Hardman, J.G., L.E. Limbird, P.B. Molinoff, R.W. Ruddon, A.G. Goodman (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill, 1996., p. 1013
Benzimidazole prevent tubulin polymerization or spindle movement and their administration can result in aneuploidy.
Klaassen, C.D., M.O. Amdur, Doull J. (eds.). Casarett and Doull's Toxicology. The Basic Science of Poisons. 5th ed. New York, NY: McGraw-Hill, 1995., p. 253
API SUPPLIERS
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 15105
Submission : 2000-10-13
Status : Inactive
Type : II
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 29045
Submission : 2015-01-21
Status : Inactive
Type : II
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 6167
Submission : 1986-01-03
Status : Inactive
Type : II
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USDMF
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ABOUT THIS PAGE
A Benzimidazole manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Benzimidazole, including repackagers and relabelers. The FDA regulates Benzimidazole manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Benzimidazole API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Benzimidazole supplier is an individual or a company that provides Benzimidazole active pharmaceutical ingredient (API) or Benzimidazole finished formulations upon request. The Benzimidazole suppliers may include Benzimidazole API manufacturers, exporters, distributors and traders.
click here to find a list of Benzimidazole suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Benzimidazole DMF (Drug Master File) is a document detailing the whole manufacturing process of Benzimidazole active pharmaceutical ingredient (API) in detail. Different forms of Benzimidazole DMFs exist exist since differing nations have different regulations, such as Benzimidazole USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Benzimidazole DMF submitted to regulatory agencies in the US is known as a USDMF. Benzimidazole USDMF includes data on Benzimidazole's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Benzimidazole USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Benzimidazole suppliers with USDMF on PharmaCompass.
Benzimidazole Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Benzimidazole GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Benzimidazole GMP manufacturer or Benzimidazole GMP API supplier for your needs.
A Benzimidazole CoA (Certificate of Analysis) is a formal document that attests to Benzimidazole's compliance with Benzimidazole specifications and serves as a tool for batch-level quality control.
Benzimidazole CoA mostly includes findings from lab analyses of a specific batch. For each Benzimidazole CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Benzimidazole may be tested according to a variety of international standards, such as European Pharmacopoeia (Benzimidazole EP), Benzimidazole JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Benzimidazole USP).
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