Find Benziodarone manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: 68-90-6, Amplivix, Dilafurane, Cardivix, Dila-vasal, Corofam
Molecular Formula
C17H12I2O3
Molecular Weight
518.08  g/mol
InChI Key
CZCHIEJNWPNBDE-UHFFFAOYSA-N
FDA UNII
75CL65GTYR

Benziodarone
Benziodarone is a uricostatic and a uricosuric agent which is sold also under the name Amplivex-Labaz. It is used in the treatment of gout. It was withdrawn from France markets and British markets due to its effects causing Jaundice in patients.
1 2D Structure

Benziodarone

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2-ethyl-1-benzofuran-3-yl)-(4-hydroxy-3,5-diiodophenyl)methanone
2.1.2 InChI
InChI=1S/C17H12I2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3
2.1.3 InChI Key
CZCHIEJNWPNBDE-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)O)I
2.2 Other Identifiers
2.2.1 UNII
75CL65GTYR
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-ethyl-3-benzofuranyl-4-hydroxy-3,5-diiodophenyl Ketone

2. Algocor

3. Amplivix

4. Cardivix

5. Dila-vasal

6. Dilafurane

2.3.2 Depositor-Supplied Synonyms

1. 68-90-6

2. Amplivix

3. Dilafurane

4. Cardivix

5. Dila-vasal

6. Corofam

7. Coronal-crinos

8. Retrangor

9. Benziodaron

10. Carofam

11. Dilacoron

12. L 2329

13. 2329 Labaz

14. Nsc 82133

15. 2-ethyl-3-benzofuranyl 4-hydroxy-3,5-diiodophenyl Ketone

16. Nsc-82133

17. 75cl65gtyr

18. 2-ethyl-3-(3',5'-diiodo-4'-hydroxybenzoyl)-cumarone

19. Benzofuran, 3-(3,5-diiodo-4-hydroxybenzoyl)-2-ethyl-

20. 3,5-diiodo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl Ketone

21. Chembl232201

22. Corofam;dilacoron;nsc 82133

23. (2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-diiodophenyl)methanone

24. Methanone, (2-ethyl-3-benzofuranyl)(4-hydroxy-3,5-diiodophenyl)-

25. Aethyl-2-(3',5'-dijod-4'-oxybenzoyl)-3 Cumaron

26. Ncgc00160408-01

27. Plexocardio

28. Flanicone

29. Ketone, 2-ethyl-3-benzofuranyl 4-hydroxy-3,5-diiodophenyl

30. Ketone, 3,5-diiodo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl

31. Uricor

32. L-2329

33. Dsstox_cid_26134

34. Dsstox_rid_81367

35. Dsstox_gsid_46134

36. Benziodarona

37. Benziodaronum

38. Benzoiodarone

39. Benziodaronum [inn-latin]

40. Cas-68-90-6

41. Benziodarona [inn-spanish]

42. Einecs 200-695-2

43. Unii-75cl65gtyr

44. Brn 1257683

45. Amplivix (tn)

46. Benziodarone [inn:ban:dcf:jan]

47. Ketone,5-diiodophenyl

48. Aethyl-2-(3',5'-dijod-4'-oxybenzoyl)-3 Cumaron [german]

49. Benziodarone (jan/inn)

50. Benziodarone [mi]

51. Benziodarone [inn]

52. Benziodarone [jan]

53. Methanone,5-diiodophenyl)-

54. Benziodarone [mart.]

55. Benziodarone [who-dd]

56. Schembl308541

57. Dtxsid1046134

58. Chebi:135814

59. Nsc82133

60. Zinc3875456

61. Tox21_111793

62. (2-ethyl-1-benzofuran-3-yl)-(4-hydroxy-3,5-diiodophenyl)methanone

63. Bdbm50209206

64. Mfcd00868246

65. Akos015994715

66. Tox21_111793_1

67. Db13277

68. Ks-1133

69. Ncgc00160408-02

70. Ncgc00160408-03

71. Ncgc00160408-06

72. E1290

73. Ft-0662545

74. D01833

75. T72830

76. Q4890775

77. 2-ethylbenzofuranyl 4-hydroxy-3,5-diiodophenyl Ketone

78. (2-ethyl-1-benzofuran-3-yl)(4-hydroxy-3,5-diiodophenyl)methanone #

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 518.08 g/mol
Molecular Formula C17H12I2O3
XLogP35.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass517.88759 g/mol
Monoisotopic Mass517.88759 g/mol
Topological Polar Surface Area50.4 Ų
Heavy Atom Count22
Formal Charge0
Complexity405
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Uricosuric Agents

Gout suppressants that act directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma. (See all compounds classified as Uricosuric Agents.)


4.2 ATC Code

C - Cardiovascular system

C01 - Cardiac therapy

C01D - Vasodilators used in cardiac diseases

C01DX - Other vasodilators used in cardiac diseases

C01DX04 - Benziodarone


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ABOUT THIS PAGE

Benziodarone Manufacturers

A Benziodarone manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Benziodarone, including repackagers and relabelers. The FDA regulates Benziodarone manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Benziodarone API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Benziodarone Suppliers

A Benziodarone supplier is an individual or a company that provides Benziodarone active pharmaceutical ingredient (API) or Benziodarone finished formulations upon request. The Benziodarone suppliers may include Benziodarone API manufacturers, exporters, distributors and traders.

Benziodarone GMP

Benziodarone Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Benziodarone GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Benziodarone GMP manufacturer or Benziodarone GMP API supplier for your needs.

Benziodarone CoA

A Benziodarone CoA (Certificate of Analysis) is a formal document that attests to Benziodarone's compliance with Benziodarone specifications and serves as a tool for batch-level quality control.

Benziodarone CoA mostly includes findings from lab analyses of a specific batch. For each Benziodarone CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Benziodarone may be tested according to a variety of international standards, such as European Pharmacopoeia (Benziodarone EP), Benziodarone JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Benziodarone USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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