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Benzocaine

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ACTIVE PHARMA INGREDIENTS

32 API Suppliers, 11 USDMF, 6 CEP/COS, 1 JDMF, 5 EU WC, 19 NDC API, 22 Listed Suppliers, $ API Reference Price

32 API Suppliers
11 USDMF
6 CEP/COS
1 JDMF
5 EU WC
19 NDC API
22 Listed Suppliers
$ API Reference Price

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2 Intermediates Suppliers

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47 FDF Dossiers, 3 Europe, 2 Canada, 34 South Africa, 8 Listed Dossiers

47 FDF Dossiers
3 Europe
2 Canada
34 South Africa
8 Listed Dossiers

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14 Rochem International Inc
11 SPI Pharma
2 Seqens
29 DKSH
3 Pharm-RX Chemical
5 Faran Shimi Pharmaceutical
9 Boai NKY Pharmaceuticals Ltd
11 Gangwal Healthcare
21 Nanjing Well Pharmaceutical
1 Pfanstiehl
1 Capital Farma
4 ACG Worldwide
22 Actylis
2 Aeon Procare
1 Alcedo Pharmachem
2 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd
1 Avesta Pharma
42 BASF
8 Beneo
1 Bioplus Life Sciences
6 Clariant
11 Corel Pharma Chem
5 Finar
14 Gangwal Chemicals
2 Huzhou Sunflower Pharmaceutical
1 Ideal Cures Pvt Ltd
2 Ingredion Pharma Solutions
11 Kerry
2 Kima Chemical
3 Lonza Capsugel
7 Lubrizol Life Science Health
12 Microlex e.U
1 Nanjing Bold Chemical
2 Nomisma Healthcare
2 Novo Excipients
1 Pharmatrans-Sanaq
7 Pluviaendo
1 Qualicaps
32 Roquette
15 Seppic
2 Shandong Focus Biotechnology Co., Ltd
2 Shanghai Shenmei Pharmaceutical Technology Co., Ltd
1 Shanghai Welltone Material Technology Co., Ltd
1 Shijiazhuang Huaxu Pharmaceutical
2 Sigachi Industries
2 The Dow Chemical Company
2 Ulanqab Kema New Material
2 Valens Pharmachem
3 Zhejiang Huakang Pharmaceutical

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25 APIs, 1 FDF Dossiers

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1 EDQM , 1 USP , 4 JP , 1 Others

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ANALYTICAL

1 Analytical Methods

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1 Analytical Methods

Pharm-Rx Benzocaine

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 38

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FDF

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FDF Dossiers

FDA Orange Book

Europe

Canada

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Chemistry

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Also known as: Ethyl 4-aminobenzoate, 94-09-7, Ethyl aminobenzoate, Ethyl p-aminobenzoate, Americaine, Anaesthesin

Molecular Formula

C₉H₁₁NO₂

Molecular Weight

165.19 g/mol

InChI Key

BLFLLBZGZJTVJG-UHFFFAOYSA-N

FDA UNII

U3RSY48JW5

A surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.

Benzocaine is a Standardized Chemical Allergen. The physiologic effect of benzocaine is by means of Increased Histamine Release, and Cell-mediated Immunity.

1 2D Structure

Benzocaine

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

ethyl 4-aminobenzoate

2.1.2 InChI

InChI=1S/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3

2.1.3 InChI Key

BLFLLBZGZJTVJG-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CCOC(=O)C1=CC=C(C=C1)N

2.2 Other Identifiers

2.2.1 UNII

U3RSY48JW5

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 4-aminobenzoic Acid Ethyl Ester

2. Acetate, Benzocaine

3. Americaine

4. Anaesthesin

5. Anesthesin

6. Bensokain

7. Benzocaine Acetate

8. Benzocaine Formate

9. Benzocaine Hydrobromide

10. Benzocaine Hydrochloride

11. Benzocaine Methanesulfonate

12. Ethoform

13. Ethyl Aminobenzoate

14. Formate, Benzocaine

15. Hydrobromide, Benzocaine

16. Hydrochloride, Benzocaine

17. Methanesulfonate, Benzocaine

2.3.2 Depositor-Supplied Synonyms

1. Ethyl 4-aminobenzoate

2. 94-09-7

3. Ethyl Aminobenzoate

4. Ethyl P-aminobenzoate

5. Americaine

6. Anaesthesin

7. Parathesin

8. Norcaine

9. Parathesine

10. Anesthesin

11. 4-aminobenzoic Acid Ethyl Ester

12. Ethoform

13. Orthesin

14. Amben Ethyl Ester

15. P-carbethoxyaniline

16. Anaesthin

17. Anestezin

18. Anesthesine

19. Anesthone

20. Dermoplast

21. Hurricaine

22. Identhesin

23. Keloform

24. Norcain

25. Topcaine

26. Baby Anbesol

27. Anaesthan-syngala

28. Ora-jel

29. Benzocainum

30. Solu H

31. P-ethoxycarboxylic Aniline

32. 4-carbethoxyaniline

33. Benzoic Acid, 4-amino-, Ethyl Ester

34. P-(ethoxycarbonyl)aniline

35. Ethyl P-aminophenylcarboxylate

36. Dextran Sulfate Sodium

37. 9011-18-1

38. Benzocaina

39. Ethyl Paba

40. 4-(ethoxycarbonyl)aniline

41. P-aminobenzoic Acid Ethyl Ester

42. Aethoform

43. Benzoic Acid, P-amino-, Ethyl Ester

44. Ethyl4-aminobenzoate

45. 4-aminobenzoic Acid, Ethyl Ester

46. 4-amino-benzoic Acid Ethyl Ester

47. Ethylester Kyseliny P-aminobenzoove

48. Ethyl-p-aminobenzoate

49. Flavamed

50. Subcutin

51. P-aminobenzoic Acid, Ethyl Ester

52. Chebi:116735

53. Nsc-4688

54. Mfcd00007892

55. Nsc-41531

56. U3rsy48jw5

57. Ar01

58. 4-aminobenzoic Acid-ethyl Ester

59. Anaesthesinum

60. Ethoforme

61. Norcainum

62. Ar-01

63. Ethylis Aminobenzoas

64. Cas-94-09-7

65. Ncgc00016352-01

66. Anestezin [russian]

67. Chloraseptic

68. Dextran Sulfate Sodium Salt

69. Otocain

70. Outgro

71. Dsstox_cid_1804

72. Wln: Zr Dvo2

73. Dsstox_rid_76338

74. Aethylium Paraminobenzoicum

75. Benzocainum [inn-latin]

76. Dsstox_gsid_21804

77. Benzocaina [inn-spanish]

78. Ethyl Aminobenzoate (van)

79. Caswell No. 430a

80. Finafta

81. Parathesin (tn)

82. Smr000059025

83. Ethylaminobenzoate-4

84. H-4-abz-oet

85. Hsdb 7225

86. Ethylester Kyseliny P-aminobenzoove [czech]

87. Benzocaine (usp/inn)

88. Sr-05000001573

89. Einecs 202-303-5

90. Nsc 41531

91. P-aminobenzoic Ethyl Ester

92. Unii-u3rsy48jw5

93. Epa Pesticide Chemical Code 097001

94. Brn 0638434

95. Benzoak

96. Benzocaine [usp:inn:ban]

97. Vagisil

98. Ai3-02081

99. Benzocaine Usp

100. Diet Ayds

101. Orabase-b

102. Slim Mint Gum

103. Prestwick_991

104. 4-carboethoxyaniline

105. Ethyl 4aminobenzoate

106. Ethyl 4-aminobenzate

107. Ethyl 4-aminobezoate

108. Outgro (salt/mix)

109. Anbesol (salt/mix)

110. Vagisil (salt/mix)

111. Ethyl-4-aminobenzoate

112. P-ethoxycarbonylaniline

113. 4-ethoxycarbonylaniline

114. Ethyl P-amino-benzoate

115. Ethyl-p-amino-benzoate

116. Ethyl Aminobenzoic Acid

117. Cough-x (salt/mix)

118. Spectrum_000074

119. Ethyl 4-amino-benzoate

120. Benzocaine [mi]

121. Ethyl 4-(amino)benzoate

122. Benzocaine [inn]

123. Ethyl P-aminobenzoic Acid

124. Prestwick0_000712

125. Prestwick1_000712

126. Prestwick2_000712

127. Prestwick3_000712

128. Spectrum2_000117

129. Spectrum3_000314

130. Spectrum4_000249

131. Spectrum5_000860

132. Benzocaine [hsdb]

133. Ethyl 4-aminobenzoic Acid

134. Benzocaine [vandf]

135. Epitope Id:114084

136. Ethyl Paba [inci]

137. Benzocaine [mart.]

138. Benzocaine [usp-rs]

139. Benzocaine [who-dd]

140. Benzocaine [who-ip]

141. Sampl3, G4

142. Ethyl Aminobenzoate (jp17)

143. Oprea1_750694

144. Oprea1_827402

145. Schembl25100

146. Bspbio_000923

147. Bspbio_001908

148. Kbiogr_000658

149. Kbioss_000474

150. 4-(ethoxycarbonyl)phenylamine

151. 4-14-00-01129 (beilstein Handbook Reference)

152. Ae-562/40377256

153. Mls001331704

154. Mls002153970

155. Divk1c_000932

156. Ethyl 4-aminobenzoate, 98%

157. Spectrum1500139

158. (p-(ethoxycarbonyl)phenylamine

159. Ethyl P-aminobenzenecarboxylate

160. Spbio_000134

161. Spbio_002844

162. Bpbio1_001017

163. Chembl278172

164. Dtxsid8021804

165. Dextran Sulfate Sodium (dst-h)

166. Ethyl Para Amino Benzoate

167. Hms502o14

168. Kbio1_000932

169. Kbio2_000474

170. Kbio2_003042

171. Kbio2_005610

172. Kbio3_001408

173. P-amino Benzoic Acid Ethyl Ester

174. 4-amino Benzoic Acid Ethyl Ester

175. Benzocaine [ep Monograph]

176. Ethyl Aminobenzoate [jan]

177. Nsc4688

178. Dextran Sulfate Sodium (kmds-h)

179. Ninds_000932

180. Bdbm197282

181. Benzocaine [usp Monograph]

182. Dextran Sulfate Sodium (ds-m-1)

183. Hms1570o05

184. Hms1920g09

185. Hms2091m11

186. Hms2097o05

187. Hms2233h21

188. Hms3371d08

189. Hms3652h13

190. Hms3714o05

191. Hms3885b11

192. Pharmakon1600-01500139

193. Benzocainum [who-ip Latin]

194. Component Of Tympagesic (salt/mix)

195. Cs-b0934

196. Hy-y0258

197. Nsc41531

198. Str01509

199. Tox21_110391

200. Tox21_301149

201. Ccg-38918

202. Nsc755909

203. S4210

204. Stk043620

205. Zinc12358719

206. Akos000119763

207. Benzocaine 1.0 Mg/ml In Acetonitrile

208. Benzocaine 100 Microg/ml In Methanol

209. Tox21_110391_1

210. Ac-8127

211. Db01086

212. Dextran, Hydrogen Sulfate, Sodium Salt

213. Nsc-755909

214. Idi1_000932

215. Benzocaine, Purum, >=99.0% (hplc)

216. Benzocaine, Tested According To Ph.eur.

217. Ncgc00016352-02

218. Ncgc00016352-03

219. Ncgc00016352-04

220. Ncgc00016352-07

221. Ncgc00094598-01

222. Ncgc00094598-02

223. Ncgc00255047-01

224. Ethyl 4-aminobenzoate, 98.0-101.0%

225. Sbi-0051293.p003

226. Component Of Solarcaine Aerosol (salt/mix)

227. A0271

228. Ab00051923

229. Bb 0258778

230. Ft-0624536

231. Ft-0625762

232. Ft-0662548

233. Sw197074-3

234. A14560

235. C07527

236. D00552

237. Ab00051923_09

238. Ab00051923_10

239. Component Of Anbesol Maximum Strength (salt/mix)

240. A860898

241. A930377

242. Aminobenzoic Acid Impurity B [ep Impurity]

243. Q422745

244. Ethyl 4-aminobenzoate, Saj First Grade, >=99.0%

245. Q-200688

246. Sr-05000001573-1

247. Sr-05000001573-3

248. Brd-k75466013-001-05-2

249. Brd-k75466013-001-08-6

250. Ethyl 4-aminobenzoate, Vetec(tm) Reagent Grade, 98%

251. F2190-0448

252. 4-aminobenzoic Acid-ethyl Ester 1000 Microg/ml In Methanol

253. Benzocaine, European Pharmacopoeia (ep) Reference Standard

254. Benzocaine, United States Pharmacopeia (usp) Reference Standard

255. Benzocaine, Pharmaceutical Secondary Standard; Certified Reference Material

2.4 Create Date

2005-03-25

3 Chemical and Physical Properties

Molecular Formula	C₉H₁₁NO₂
Molecular Weight	165.19 g/mol
XLogP3	1.9
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	165.078978594 g/mol
Monoisotopic Mass	165.078978594 g/mol
Topological Polar Surface Area	52.3 Å²
Heavy Atom Count	12
Formal Charge	0
Complexity	151
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Therapeutic Uses

Indicated for the relief of: canker sores, cold sores, or fever blisters: benzocaine (gel and topical solution); gingival or oral mucosal pain (i.e., pain caused by mouth or gum irritation, inflammation, lesions, or minor dental procedures): benzocaine (gel, dental paste, lozenges, and topical solution); dental prosthetic pain (i.e., pain or irritation caused by dentures or other dental or orthodontic appliances): benzocaine (dental paste, gel ointment, and topical solution); teething pain: benzocaine (7.5% and 10% gel); and toothache: benzocaine (10% and 20% gel and topical solution).

Thomson.Micromedex. Drug Information for the Health Care Professional. 24th ed. Volume 1. Plus Updates. Content Reviewed by the United States Pharmacopeial Convention, Inc. Greenwood Village, CO. 2004., p. 153

Indicated to suppress the gag reflex and/or other laryngeal and esophageal reflexes to facilitate dental examination or procedures (including oral surgery), endoscopy, or intubation: benzocaine (gel, topical aerosol, and topical solution). /Included in US product labeling/

Indicated to provide topical anesthesia of accessible mucous membranes prior to examination, endoscopy or instrumentation, or other procedures involving the: esophagus: benzocaine (gel and topical solution)); larynx: benzocaine (gel and topical solution); mouth, In dental procedures and oral surgery: benzocaine (gel, topical aerosol, and topical solution); nasal cavity: benzocaine (gel); pharynx or throat: benzocaine (gel, topical aerosol, and topical solution); rectum: benzocaine (gel); respiratory tract or trachea: benzocaine (gel, topical aerosol, and topical solution); urinary tract: benzocaine (gel); and vagina: benzocaine (gel).

Anesthetic (local).

O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 186

(VET): Local (usually surface) anesthetic.

O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 186

4.2 Drug Warning

Infants and the elderly were more likely to develop toxic methemoglobinemia after benzocaine exposure. Other risk factors included genetic reductase deficiencies, exposure to high doses of anesthetic, and presence of denuded skin and mucous membranes. Because of the potential for severe complications, methemoglobinemia should be corrected promptly in compromised patients and those with toxic benzocaine concentrations. The possibility of masking symptoms during general anesthesia carries special risk of use of this agent in the preanesthesia setting.

PMID:8069004 Rodriguez LF et al; Ann Pharmacother 28 (5): 643-9 (1994)

Use of otic anesthetics may mask symptoms of a fulminating middle ear infection (acute otitis media). Otic solutions containing benzocaine should not be used in the presence of a perforated tympanic membrane.

McEvoy, G.K. (ed.). American Hospital Formulary Service- Drug Information 2004. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2004 (Plus Supplements)., p. 2695

When applied topically as recommended, benzocaine is relatively nontoxic, however, sensitization may occur.

McEvoy, G.K. (ed.). American Hospital Formulary Service- Drug Information 2004. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2004 (Plus Supplements)., p. 3411

When used as a male genital desensitizer, benzocaine generally does not adversely affect orgasm in female sexual partners and does not appear to anesthetize the clitoris or vagina.

McEvoy, G.K. (ed.). American Hospital Formulary Service- Drug Information 2004. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2004 (Plus Supplements)., p. 3411

For more Drug Warnings (Complete) data for BENZOCAINE (9 total), please visit the HSDB record page.

4.3 Drug Indication

Benzocaine is indicated for local anesthesia in dentistry, minor trauma, and as preparation for infiltrative anesthesia. Benzocaine products are indicated for topical anesthesia in a wide variety of conditions including skin irritation, oral pain, and hemorrhoids.

Treatment of oropharyngeal pain

5 Pharmacology and Biochemistry

5.1 Pharmacology

Benzocaine is indicated for use as a topical anesthetic. It has a duration of action of approximately 10 minutes and a wide therapeutic window. Patients should be counselled regarding the risks of methemoglobinemia.

5.2 MeSH Pharmacological Classification

Anesthetics, Local

Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. (See all compounds classified as Anesthetics, Local.)

5.3 FDA Pharmacological Classification

5.3.1 Active Moiety

BENZOCAINE

5.3.2 FDA UNII

U3RSY48JW5

5.3.3 Pharmacological Classes

Cell-mediated Immunity [PE]; Copper Absorption Inhibitor [EPC]; Decreased Copper Ion Absorption [PE]; Increased Histamine Release [PE]; Sigma-1 Agonist [EPC]; Sigma-1 Receptor Agonists [MoA]; Skin Barrier Activity [PE]; Standardized Chemical Allergen [EPC]; Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC]; Uncompetitive NMDA Receptor Antagonists [MoA]; Allergens [CS]

5.4 ATC Code

C05AD03

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355

C - Cardiovascular system

C05 - Vasoprotectives

C05A - Agents for treatment of hemorrhoids and anal fissures for topical use

C05AD - Local anesthetics

C05AD03 - Benzocaine

D - Dermatologicals

D04 - Antipruritics, incl. antihistamines, anesthetics, etc.

D04A - Antipruritics, incl. antihistamines, anesthetics, etc.

D04AB - Anesthetics for topical use

D04AB04 - Benzocaine

N - Nervous system

N01 - Anesthetics

N01B - Anesthetics, local

N01BA - Esters of aminobenzoic acid

N01BA05 - Benzocaine

R - Respiratory system

R02 - Throat preparations

R02A - Throat preparations

R02AD - Anesthetics, local

R02AD01 - Benzocaine

5.5 Absorption, Distribution and Excretion

Branchial and urinary elimination of benzocaine residues was evaluated in adult rainbow trout, Oncorhynchus mykiss, given a single dorsal aortic dose of 14(C)-benzocaine hydrochloride. Branchial elimination of benzocaine residues was rapid and accounted for 59.2% of the dose during the first 3 h after dosing. Renal elimination of radioactivity was considerably slower; the kidney excreted 2.7% dose within 3 h and 9.0% within 24 hr. Gallbladder bile contained 2.0% dose 24 hr after injection. Of the radioactivity in radiochromatograms from water taken 3 min after injection, 87.3% was benzocaine and 12.7% was N-acetylated benzocaine. After 60 min, 32.7% was benzocaine and 67.3% was N-acetylated benzocaine. Of the radioactivity in radiochromatograms from urine taken 1 hr after dosing, 7.6% was para-aminobenzoic acid, 59.7% was N-acetylated para-aminobenzoic acid, 19.5% was benzocaine, and 8.0% was N-acetylated benzocaine. The proportion of the radioactivity in urine changed with time so that by 20 hr, 1.0% was para-aminobenzoic acid and 96.6% was N-acetylated para-aminobenzoic acid. Benzocaine and a more hydrophobic metabolite, N-acetylated benzocaine, were eliminated primarily through the gills; renal and biliary pathways were less significant elimination routes for benzocaine residues.

PMID:1897251 Meinertz JR et al; Xenobiotica 21 (4): 525-33 (1991)

5.6 Metabolism/Metabolites

Benzocaine undergoes ester hydrolysis to form 4-aminobenzoic acid, acetylation to form acetylbenzocaine, or N-hydroxylation to form benzocaine hydroxide. 4-aminobenzoic acid can be acetylated or acetylbenzocaine can undergo ester hydrolysis to form 4-acetaminobenzoic acid.

The effect of dose and enzymatic inhibition on the percutaneous absorption and metabolism of benzocaine was studied in vitro in the hairless guinea pig. At the dose level of 2 ug/sq cm, benzocaine was rapidly absorbed and extensively metabolized (80%) by acetyltransferase. As the applied dose of benzocaine was increased to 40 and 200 ug/sq cm, N-acetylation of benzocaine decreased to 44 and 34%, respectively, suggesting saturation of the acetyltransferase system. Total 14(C) absorption after benzocaine application was not significantly different between control and enzyme-inhibited skin and therefore does not appear to be affected by the extent of benzocaine metabolism during percutaneous penetration. Skin provides a significant first-pass metabolic effect for therapeutic doses of percutaneously absorbed benzocaine, and the primary metabolite formed, acetylbenzocaine, is biologically active.

PMID:8737920 Kraeling ME et al; Skin Pharmacol 9 (3): 221-30 (1996)

5.7 Mechanism of Action

Benzocaine diffuses into nerve cells where it binds to sodium channels, preventing the channels from opening, and blocking the influx of sodium ions. Nerve cells unable to allow sodium into cells cannot depolarize and conduct nerve impulses.

Benzocaine reversibly stabilizes the neuronal membrane with decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited thereby blocking the initiation and conduction of nerve impulses.

Physicians Desk Reference. 58th ed. Thomson PDR. Montvale, NJ 2004., p. 1130

API SUPPLIERS

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USDMF

01

Apex Healthcare Ltd

India

CPHI Middle east

Not Confirmed

02

Apex Healthcare Ltd

India

CPHI Middle east

Not Confirmed

03

Archimica Srl

Italy

CPHI Middle east

Not Confirmed

04

Changzhou Sunlight Pharmaceutical Co...

China

India

CPHI Middle east

Not Confirmed

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CEP/COS

01

APEX HEALTHCARE LIMITED Ankleshwar ...

India

China

Cosmoprof India

Not Confirmed

06

PHARMATEC Q LTD. Clonee IE

Country

Cosmoprof India

Not Confirmed

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JDMF

01

Changzhou Sunlight Pharmaceutical C...

China

Antibody Engineering

Not Confirmed

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EU WC

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NDC API

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Listed Suppliers

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API Reference Price

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