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ACTIVE PHARMA INGREDIENTS

10 API Suppliers, 8 USDMF, 1 EU WC, 4 NDC API, 4 Listed Suppliers

10 API Suppliers
8 USDMF
1 EU WC
4 NDC API
4 Listed Suppliers

FINISHED DOSAGE FORMULATIONS

13 FDF Dossiers, 13 FDA Orange Book

13 FDF Dossiers
13 FDA Orange Book

DRUG PRODUCT COMPOSITIONS

TABLET;ORAL - 25MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, TABLET;ORAL - 50MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

drugProductComposition
TABLET;ORAL - 25MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
TABLET;ORAL - 50MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc, 6 SPI Pharma, 2 Seqens, 3 DKSH, 4 Faran Shimi Pharmaceutical, 1 Boai NKY Pharmaceuticals Ltd, 13 Gangwal Healthcare, 4 Nanjing Well Pharmaceutical, 1 ACG Worldwide, 5 Actylis, 1 Aeon Procare, 6 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 19 BASF, 10 Corel Pharma Chem, 6 DFE Pharma, 1 Finar, 11 Gangwal Chemicals, 7 Ideal Cures Pvt Ltd, 3 Ingredion Pharma Solutions, 38 Kerry, 3 Kima Chemical, 6 Lonza Capsugel, 14 Microlex e.U, 1 Nanjing Bold Chemical, 2 Nomisma Healthcare, 3 Novo Excipients, 3 Pharmatrans-Sanaq, 4 Pluviaendo, 3 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 1 Qualicaps, 26 Roquette, 13 Seppic, 5 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Shijiazhuang Huaxu Pharmaceutical, 11 Sigachi Industries, 2 The Dow Chemical Company, 4 Vasa Pharmachem, 1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

71 Fillers, Diluents & Binders, 52 Coating Systems & Additives, 33 Direct Compression, 31 Controlled & Modified Release, 21 Solubilizers, 21 Thickeners and Stabilizers, 21 Disintegrants & Superdisintegrants, 19 Lubricants & Glidants, 19 Granulation, 18 Film Formers & Plasticizers, 18 Co-Processed Excipients, 14 Parenteral, 12 Topical, 11 Taste Masking, 8 Chewable & Orodispersible Aids, 7 Emulsifying Agents, 6 API Stability Enhancers, 5 Empty Capsules, 4 Coloring Agents, 4 Vegetarian Capsules, 3 Rheology Modifiers, 2 Surfactant & Foaming Agents, 1 Soft Gelatin

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2 Finished Drug Prices

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REF. STANDARDS & IMPURITIES

1 USP , 5 Others

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Synopsis

ACTIVE PHARMA INGREDIENTS

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KDMF

NDC API

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Chemistry

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Also known as: 1027-30-1, D-benzphetamine hydrochloride, N-benzyl-n-methyl-1-phenylpropan-2-amine;hydrochloride, N-benzyl-n-methyl-1-phenyl-2-propanamine hydrochloride, Didrex (tn), N-benzyl-n,alpha-dimethylphenethylamine hydrochloride

Molecular Formula

C₁₇H₂₂ClN

Molecular Weight

275.8 g/mol

InChI Key

ANFSNXAXVLRZCG-UHFFFAOYSA-N

1 2D Structure

Benzphetamine

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

N-benzyl-N-methyl-1-phenylpropan-2-amine;hydrochloride

2.1.2 InChI

InChI=1S/C17H21N.ClH/c1-15(13-16-9-5-3-6-10-16)18(2)14-17-11-7-4-8-12-17;/h3-12,15H,13-14H2,1-2H3;1H

2.1.3 InChI Key

ANFSNXAXVLRZCG-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC(CC1=CC=CC=C1)N(C)CC2=CC=CC=C2.Cl

2.2 Synonyms

2.2.1 Depositor-Supplied Synonyms

1. 1027-30-1

2. D-benzphetamine Hydrochloride

3. N-benzyl-n-methyl-1-phenylpropan-2-amine;hydrochloride

4. N-benzyl-n-methyl-1-phenyl-2-propanamine Hydrochloride

5. Didrex (tn)

6. N-benzyl-n,alpha-dimethylphenethylamine Hydrochloride

7. Dtxsid70908004

8. N,alpha-dimethyl-n-(phenylmethyl)benzeneethanamine Hydrochloride

9. Nsc10937

10. Benzeneethanamine, N,alpha-dimethyl-n-(phenylmethyl)-, Hydrochloride (1:1)

11. 5411-22-3 (hcl)

12. Ft-0662617

13. Ft-0662619

14. D07515

15. N-benzyl-n-methyl-1-phenylpropan-2-amine--hydrogen Chloride (1/1)

16. Benzeneethanamine,.alpha.-dimethyl-n-(phenylmethyl)-, Hydrochloride, (+)-

2.3 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₁₇H₂₂ClN
Molecular Weight	275.8 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	5
Exact Mass	275.1440774 g/mol
Monoisotopic Mass	275.1440774 g/mol
Topological Polar Surface Area	3.2 Å²
Heavy Atom Count	19
Formal Charge	0
Complexity	214
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 4
Drug Name	Benzphetamine hydrochloride
PubMed Health	Benzphetamine (By mouth)
Drug Classes	Appetite Suppressant, Centrally Acting
Drug Label	DIDREX Tablets contain the anorectic agent benzphetamine hydrochloride. Benzphetamine hydrochloride is a white crystalline powder readily soluble in water and 95% ethanol. The chemical name for benzphetamine hydrochloride is d-N,-Dimethyl-N-(phenyl...
Active Ingredient	Benzphetamine hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	25mg; 50mg
Market Status	Prescription
Company	Emcure Pharms; Paddock; Kvk Tech; Tedor Pharm; Mallinckrodt; Mikart; Impax Labs

2 of 4
Drug Name	Didrex
Drug Label	DIDREX Tablets contain the anorectic agent benzphetamine hydrochloride. Benzphetamine hydrochloride is a white crystalline powder readily soluble in water and 95% ethanol. The chemical name for benzphetamine hydrochloride is d-N,-Dimethyl-N-(phenyl...
Active Ingredient	Benzphetamine hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	50mg
Market Status	Prescription
Company	Pharmacia And Upjohn

3 of 4
Drug Name	Benzphetamine hydrochloride
PubMed Health	Benzphetamine (By mouth)
Drug Classes	Appetite Suppressant, Centrally Acting
Drug Label	DIDREX Tablets contain the anorectic agent benzphetamine hydrochloride. Benzphetamine hydrochloride is a white crystalline powder readily soluble in water and 95% ethanol. The chemical name for benzphetamine hydrochloride is d-N,-Dimethyl-N-(phenyl...
Active Ingredient	Benzphetamine hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	25mg; 50mg
Market Status	Prescription
Company	Emcure Pharms; Paddock; Kvk Tech; Tedor Pharm; Mallinckrodt; Mikart; Impax Labs

4 of 4
Drug Name	Didrex
Drug Label	DIDREX Tablets contain the anorectic agent benzphetamine hydrochloride. Benzphetamine hydrochloride is a white crystalline powder readily soluble in water and 95% ethanol. The chemical name for benzphetamine hydrochloride is d-N,-Dimethyl-N-(phenyl...
Active Ingredient	Benzphetamine hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	50mg
Market Status	Prescription
Company	Pharmacia And Upjohn

API SUPPLIERS

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - TABLET;ORAL - 25MG **Federal Registe...DOSAGE - TABLET;ORAL - 25MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 12427

DOSAGE - TABLET;ORAL - 50MG **Federal Registe...DOSAGE - TABLET;ORAL - 50MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 12427

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BENZPHETAMINE HYDROCHLORIDE

ACCESS ALL DATA

Browse all information

CHEMISTRY

Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

10 API Suppliers

8 USDMF

1 EU WC

4 NDC API

4 Listed Suppliers

FINISHED DOSAGE FORMULATIONS

13 FDF Dossiers

13 FDA Orange Book

DRUG PRODUCT COMPOSITIONS

TABLET;ORAL - 25MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

TABLET;ORAL - 50MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc

6 SPI Pharma

2 Seqens

3 DKSH

4 Faran Shimi Pharmaceutical

1 Boai NKY Pharmaceuticals Ltd

13 Gangwal Healthcare

4 Nanjing Well Pharmaceutical

1 ACG Worldwide

5 Actylis

1 Aeon Procare

6 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

19 BASF

10 Corel Pharma Chem

6 DFE Pharma

1 Finar

11 Gangwal Chemicals

7 Ideal Cures Pvt Ltd

3 Ingredion Pharma Solutions

38 Kerry

3 Kima Chemical

6 Lonza Capsugel

14 Microlex e.U

1 Nanjing Bold Chemical

2 Nomisma Healthcare

3 Novo Excipients

3 Pharmatrans-Sanaq

4 Pluviaendo

3 Prachin Chemical

1 Qianhao Chemical (Hebei) Co., Ltd

1 Qualicaps

26 Roquette

13 Seppic

5 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

1 Shijiazhuang Huaxu Pharmaceutical

11 Sigachi Industries

2 The Dow Chemical Company

4 Vasa Pharmachem

1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

71 Fillers, Diluents & Binders

52 Coating Systems & Additives

33 Direct Compression

31 Controlled & Modified Release

21 Solubilizers

21 Thickeners and Stabilizers

21 Disintegrants & Superdisintegrants

19 Lubricants & Glidants

19 Granulation

18 Film Formers & Plasticizers

18 Co-Processed Excipients

14 Parenteral

12 Topical

11 Taste Masking

8 Chewable & Orodispersible Aids

7 Emulsifying Agents

6 API Stability Enhancers

5 Empty Capsules

4 Coloring Agents

4 Vegetarian Capsules

3 Rheology Modifiers

TABLET;ORAL - 25MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons

TABLET;ORAL - 50MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons