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    Also known as: 132-69-4, Benzydamine hcl, Benzidamine hydrochloride, Benzindamine hydrochloride, Tantum, Benzydamine (hydrochloride)
    Molecular Formula
    C19H24ClN3O
    Molecular Weight
    345.9  g/mol
    InChI Key
    HNNIWKQLJSNAEQ-UHFFFAOYSA-N
    FDA UNII
    K2GI407R4Q
    Benzydamine Hydrochloride
    A benzyl-indazole having analgesic, antipyretic, and anti-inflammatory effects. It is used to reduce post-surgical and post-traumatic pain and edema and to promote healing. It is also used topically in treatment of RHEUMATIC DISEASES and INFLAMMATION of the mouth and throat.
    1 2D Structure

    Benzydamine Hydrochloride

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    3-(1-benzylindazol-3-yl)oxy-N,N-dimethylpropan-1-amine;hydrochloride
    2.1.2 InChI
    InChI=1S/C19H23N3O.ClH/c1-21(2)13-8-14-23-19-17-11-6-7-12-18(17)22(20-19)15-16-9-4-3-5-10-16;/h3-7,9-12H,8,13-15H2,1-2H3;1H
    2.1.3 InChI Key
    HNNIWKQLJSNAEQ-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CN(C)CCCOC1=NN(C2=CC=CC=C21)CC3=CC=CC=C3.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    K2GI407R4Q
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Benzidamine

    2. Benzindamine

    3. Benzydamine

    4. Benzydamine Monohydrochloride

    5. Difflam

    6. Hydrochloride, Benzydamine

    7. Lonol

    8. Monohydrochloride, Benzydamine

    9. Novo Benzydamine

    10. Novo-benzydamine

    11. Opalgyne

    12. Pms Benzydamine

    13. Pms-benzydamine

    14. Ratio Benzydamine

    15. Ratio-benzydamine

    16. Rosalgin

    17. Sun Benz

    18. Sun-benz

    19. Tantum

    20. Tantum Topico

    2.3.2 Depositor-Supplied Synonyms

    1. 132-69-4

    2. Benzydamine Hcl

    3. Benzidamine Hydrochloride

    4. Benzindamine Hydrochloride

    5. Tantum

    6. Benzydamine (hydrochloride)

    7. Af-864

    8. Nsc-759276

    9. 132-69-4 (hcl)

    10. K2gi407r4q

    11. Benalgin

    12. {3-[(1-benzyl-1h-indazol-3-yl)oxy]propyl}dimethylamine Hydrochloride

    13. 1-benzyl-3-(3-(dimethylamino)propoxy)-1h-indazole Monohydrochloride

    14. 3-((1-benzyl-1h-indazol-3-yl)oxy)-n,n-dimethylpropan-1-amine Hydrochloride

    15. 1-propanamine, N,n-dimethyl-3-((1-(phenylmethyl)-1h-indazol-3-yl)oxy)-, Monohydrochloride

    16. Benzidan

    17. Benzyrin

    18. Difflam

    19. Dorinamin

    20. Enzamin

    21. Epirotin

    22. Flogaton

    23. Imotryl

    24. Oxinazin

    25. Ririlim

    26. Riripen

    27. Salyzoron

    28. Tamas

    29. Verax

    30. 1-benzyl-3-(3-(dimethylamino)propoxy)-1h-indazole Hydrochloride

    31. 1-benzyl-3-(3-[dimethylamino]propoxy)-1h-indazole Hydrochloride

    32. Dsstox_cid_25293

    33. Dsstox_rid_80786

    34. Dsstox_gsid_45293

    35. 1-benzyl-3-[3-(dimethylamino)propoxy]-1h-indazole Hydrochloride

    36. 3-(1-benzylindazol-3-yl)oxy-n,n-dimethylpropan-1-amine;hydrochloride

    37. Smr000544402

    38. Ncgc00016397-01

    39. Cas-132-69-4

    40. Einecs 205-076-0

    41. Af 864

    42. Af864

    43. Benzydamine Hydrochloride [usan:jan]

    44. Unii-k2gi407r4q

    45. Sr-01000799149

    46. Benzydamine, Hcl

    47. Prestwick_403

    48. Tantum (tn)

    49. 1-benzyl-3-gamma-dimethylaminopropoxy-1h-indazole Hydrochloride

    50. 1-propanamine, N,n-dimethyl-3-((1-(phenylmethyl)-1h-indazol-3-yl)oxy)-, Hydrochloride

    51. Schembl42644

    52. Benzydaminehydrochloride

    53. Mls001216204

    54. Mls001306431

    55. Mls001333107

    56. Mls001333108

    57. Mls002222210

    58. Not Available;benzydamine Hcl

    59. Benzydamine-[d6] Hydrochloride

    60. Chembl1528134

    61. Dtxsid1045293

    62. Chebi:31266

    63. Hms1568l16

    64. Pharmakon1600-01505975

    65. Bcp12133

    66. Tox21_110420

    67. Hy-30235a

    68. Mfcd00078957

    69. Nsc759276

    70. S4165

    71. Benzydamine Hydrochloride (jan/usan)

    72. Benzydamine Hydrochloride [mi]

    73. 1h-indazole, 1-benzyl-3-(3-(dimethylamino)propoxy)-, Monohydrochloride

    74. 3-((1-benzyl-1h-indazol-3-yl)oxy)-n,n-dimethylpropylamine Monohydrochloride

    75. Akos015994635

    76. Tox21_110420_1

    77. Ac-6791

    78. Benzydamine Hydrochloride [jan]

    79. Ccg-213582

    80. Cs-4463

    81. Hs-1002

    82. Nsc 759276

    83. Benzydamine Hydrochloride [usan]

    84. Benzydamine Hydrochloride [mart.]

    85. Ncgc00016397-04

    86. Benzydamine Hydrochloride [who-dd]

    87. 1-benzyl-3-hydroxy-1h-indazolesodiumsalt

    88. B3751

    89. Ft-0662621

    90. Sw196646-3

    91. Benzydamine Hydrochloride, Analytical Standard

    92. A14562

    93. Benzydamine Hydrochloride [ep Monograph]

    94. D01410

    95. H10439

    96. A854848

    97. J-006209

    98. Sr-01000799149-4

    99. Q27281858

    100. 1-benzyl-3-(3-(dimethylamino) Propoxy)-1h Indozale Hydrochloride

    101. 3-(1-benzyl-1h-indazol-3-yloxy)-n,n-dimethylpropan-1-amine Hydrochloride

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 345.9 g/mol
    Molecular Formula C19H24ClN3O
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count3
    Rotatable Bond Count7
    Exact Mass345.1607901 g/mol
    Monoisotopic Mass345.1607901 g/mol
    Topological Polar Surface Area30.3 Ų
    Heavy Atom Count24
    Formal Charge0
    Complexity344
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Inflammatory Agents

    Substances that reduce or suppress INFLAMMATION. (See all compounds classified as Anti-Inflammatory Agents.)

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    BAL PHARMA LIMITED Bengaluru IN

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    CEP 2021-325 - Rev 01
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    Certificate Number : CEP 2021-325 - Rev 01

    Status : Valid

    Issue Date : 2024-06-05

    Type : Chemical

    Substance Number : 2759

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    19-Jan-2021
    29-Oct-2024
    KGS
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