Synopsis
Synopsis
0
API Suppliers
0
USDMF
0
CEP/COS
0
JDMF
0
EU WC
0
KDMF
0
NDC API
0
VMF
0
Listed Suppliers
0
API
0
FDF
0
FDF Dossiers
0
FDA Orange Book
0
Europe
0
Canada
0
Australia
0
South Africa
0
Listed Dossiers
DRUG PRODUCT COMPOSITIONS
0
EDQM
0
USP
0
JP
0
Others
0
US Patents
0
US Exclusivities
0
Health Canada Patents
0
Data Compilation #PharmaFlow
0
Stock Recap #PipelineProspector
0
Weekly News Recap #Phispers
0
News #PharmaBuzz
US Medicaid
NA
Annual Reports
NA
Finished Drug Prices
NA
1. 4-oxime Uridine
2. Beta-d-n4-hydroxycytidine
3. Eidd-1931
4. N4-hydroxycytidine
1. N4-hydroxycytidine
2. Eidd-1931
3. Beta-d-n4-hydroxycytidine
4. N-hydroxycytidine
5. 3258-02-4
6. 4-n-hydroxycytidine
7. C3d11pv2o4
8. 1-[(2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one
9. 1-((2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(hydroxyimino)-3,4-dihydropyrimidin-2(1h)-one
10. 4-oxime Uridine
11. N-4-hydroxycytidine
12. Cytidine, N-hydroxy-
13. Ccris 1074
14. 1-[(2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4-(hydroxyimino)-3,4-dihydropyrimidin-2(1h)-one
15. Unii-c3d11pv2o4
16. Eidd1931
17. Beta-d-n(4)-hydroxycytidine
18. N-hydroxy-3,4-dihydrocytidine
19. Schembl5190819
20. Chembl2178720
21. Eidd 1931
22. Gtpl10735
23. Dtxsid20186274
24. Chebi:180654
25. Ex-a3655
26. Mfcd01675695
27. At13085
28. Bs-47105
29. Hy-125033
30. Cs-0088698
31. 1-((2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(hydroxyamino)pyrimidin-2(1h)-one
32. 1-((2r,3r,4s,5r)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-4-hydroxyamino-1h-pyrimidin-2-one
33. 1-[(2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)-1,2-dihydropyrimidin-2-one
34. 1-[(2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4-(hydroxyamino)pyrimidin-2-one
Molecular Weight | 259.22 g/mol |
---|---|
Molecular Formula | C9H13N3O6 |
XLogP3 | -2.2 |
Hydrogen Bond Donor Count | 5 |
Hydrogen Bond Acceptor Count | 6 |
Rotatable Bond Count | 3 |
Exact Mass | 259.08043514 g/mol |
Monoisotopic Mass | 259.08043514 g/mol |
Topological Polar Surface Area | 135 Ų |
Heavy Atom Count | 18 |
Formal Charge | 0 |
Complexity | 398 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 4 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
N4-hydroxycytidine and its prodrug [EIDD-2801] is being studied for its activity against a number of viral infections including influenza, MERS-CoV, and SARS-CoV-2.
Absorption
N4-hydroxycytidine is orally bioavailable in mice but poorly bioavailable in non-human primates.
N4-hydroxycytidine distributes into tissues where it is is phosphorylated to the 5'-triphosphate form.
N4-hydroxycytidine is phosphorylated in tissue to the active 5-triphosphate form, which is incorporated into the genome of new virions, resulting in the accumulation of inactivating mutations, known as viral error catastrophe. A [remdesivir] resistant mutant mouse hepatitis virus has also been shown to have increased sensitivity to N4-hydroxycytidine.
ABOUT THIS PAGE
96
PharmaCompass offers a list of Beta-D-N4-hydroxycytidine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Beta-D-N4-hydroxycytidine manufacturer or Beta-D-N4-hydroxycytidine supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Beta-D-N4-hydroxycytidine manufacturer or Beta-D-N4-hydroxycytidine supplier.
PharmaCompass also assists you with knowing the Beta-D-N4-hydroxycytidine API Price utilized in the formulation of products. Beta-D-N4-hydroxycytidine API Price is not always fixed or binding as the Beta-D-N4-hydroxycytidine Price is obtained through a variety of data sources. The Beta-D-N4-hydroxycytidine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Beta-D-N4-hydroxycytidine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Beta-D-N4-hydroxycytidine, including repackagers and relabelers. The FDA regulates Beta-D-N4-hydroxycytidine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Beta-D-N4-hydroxycytidine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Beta-D-N4-hydroxycytidine supplier is an individual or a company that provides Beta-D-N4-hydroxycytidine active pharmaceutical ingredient (API) or Beta-D-N4-hydroxycytidine finished formulations upon request. The Beta-D-N4-hydroxycytidine suppliers may include Beta-D-N4-hydroxycytidine API manufacturers, exporters, distributors and traders.
Beta-D-N4-hydroxycytidine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Beta-D-N4-hydroxycytidine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Beta-D-N4-hydroxycytidine GMP manufacturer or Beta-D-N4-hydroxycytidine GMP API supplier for your needs.
A Beta-D-N4-hydroxycytidine CoA (Certificate of Analysis) is a formal document that attests to Beta-D-N4-hydroxycytidine's compliance with Beta-D-N4-hydroxycytidine specifications and serves as a tool for batch-level quality control.
Beta-D-N4-hydroxycytidine CoA mostly includes findings from lab analyses of a specific batch. For each Beta-D-N4-hydroxycytidine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Beta-D-N4-hydroxycytidine may be tested according to a variety of international standards, such as European Pharmacopoeia (Beta-D-N4-hydroxycytidine EP), Beta-D-N4-hydroxycytidine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Beta-D-N4-hydroxycytidine USP).