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LGM Nicotinamide Adenine Dinucleotide

Synopsis

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Chemistry

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Also known as: Nicotinamide adenine dinucleotide, Nad+, Enzopride, Diphosphopyridine nucleotide, 53-84-9, Adenine-nicotinamide dinucleotide

Molecular Formula

C₂₁H₂₈N₇O₁₄P₂+

Molecular Weight

664.4 g/mol

InChI Key

BAWFJGJZGIEFAR-NNYOXOHSSA-O

A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)

1 2D Structure

Beta Nicotinamide Adenine Dinucleotide

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate

2.1.2 InChI

InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/p+1/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

2.1.3 InChI Key

BAWFJGJZGIEFAR-NNYOXOHSSA-O

2.1.4 Canonical SMILES

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

2.1.5 Isomeric SMILES

C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

2.2 Synonyms

2.2.1 MeSH Synonyms

1. Adenine Dinucleotide, Dihydronicotinamide

2. Coenzyme I

3. Dihydronicotinamide Adenine Dinucleotide

4. Dinucleotide, Dihydronicotinamide Adenine

5. Dinucleotide, Nicotinamide-adenine

6. Diphosphopyridine Nucleotide

7. Dpn

8. Nad

9. Nadh

10. Nadide

11. Nicotinamide Adenine Dinucleotide

12. Nicotinamide-adenine Dinucleotide

13. Nucleotide, Diphosphopyridine

2.2.2 Depositor-Supplied Synonyms

1. Nicotinamide Adenine Dinucleotide

2. Nad+

3. Enzopride

4. Diphosphopyridine Nucleotide

5. 53-84-9

6. Adenine-nicotinamide Dinucleotide

7. Nad

8. Nadidum [inn-latin]

9. Nadida [inn-spanish]

10. Nad(+)

11. Chebi:15846

12. [[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2r,3s,4r,5r)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl Hydrogen Phosphate

13. 151411-04-0

14. Nicotinamide-adenine Dinucleotide

15. Brn 3584133

16. Sr-05000001677

17. Nadide [usan:ban:inn:jan]

18. Nad Cation

19. [[(2r,3s,4r,5r)-5-[(3r)-3-aminocarbonyl-3,4-dihydro-2h-pyridin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanidyl-phosphoryl] [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl Phosphate

20. 121053-11-0

21. Naj

22. Txe

23. Spectrum_000973

24. Nicotinamide Adenine Dinucleotide (nad+)

25. [[(2~{r},3~{s},4~{r},5~{r})-5-(3-aminocarbonylpyridin-1-ium-1-yl)-4-[[5-[4-cyano-2-[(~{e})-hydroxyiminomethyl]phenoxy]-1-oxidanyl-3~{h}-2,1$l^{4}-benzoxaborol-1-yl]oxy]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{r},3~{s},4~{r},5~{r})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl Hydrogen Phosphate

26. 9jm

27. Adenosine 5'-(trihydrogen Diphosphate), P'-5'-ester With 3-(aminocarbonyl)-1-beta-d-ribofuranosylpyridinium, Inner Salt

28. Prestwick3_000741

29. Pyridinium, 3-carbamoyl-1-beta-d-ribofuranosyl-, Hydroxide, 5'-ester With Adenosine 5'-5'-(trihydrogen Pyrophosphate), Inner Salt

30. Spectrum2_001056

31. Spectrum3_000511

32. Spectrum4_000065

33. Spectrum5_001291

34. Bmse000053

35. Nadide (jan/usan/inn)

36. Bspbio_000722

37. Bspbio_002061

38. Kbiogr_000589

39. Kbioss_001453

40. Divk1c_000189

41. Spbio_001012

42. Bpbio1_000796

43. Chembl3039307

44. Schembl14478781

45. Kbio1_000189

46. Kbio2_001453

47. Kbio2_004021

48. Kbio2_006589

49. Kbio3_001561

50. Ninds_000189

51. Zinc8214766

52. Idi1_000189

53. 65085-09-8

54. C00003

55. D00002

56. 036d253

57. Sr-05000001677-1

58. Sr-05000001677-3

59. Brd-a11132253-001-01-7

60. Q26987253

61. 1-[5-o-[(5'-adenylyloxy)phosphonyl]-beta-d-ribofuranosyl]-3-(aminocarbonyl)pyridinium

62. Coconut Oil, Polymer With Benzoic Acid, Glycerol, Pentaerythritol And Phthalic Anhydride

63. 865-05-4

64. Adenosine 5'-{3-[1-(3-carbamoylpyridinio)-1,4-anhydro-d-ribitol-5-yl] Dihydrogen Diphosphate}

2.3 Create Date

2004-09-16

3 Chemical and Physical Properties

Molecular Formula	C₂₁H₂₈N₇O₁₄P₂+
Molecular Weight	664.4 g/mol
XLogP3	-5.9
Hydrogen Bond Donor Count	8
Hydrogen Bond Acceptor Count	18
Rotatable Bond Count	11
Exact Mass	664.11694759 g/mol
Monoisotopic Mass	664.11694759 g/mol
Topological Polar Surface Area	318 Å²
Heavy Atom Count	44
Formal Charge	1
Complexity	1130
Isotope Atom Count	0
Defined Atom Stereocenter Count	8
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

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API Reference Price

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K","customer":"S. KUSHALCHAND INTERNATIONAL ","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"2061","totalValueFC":"10802.6","currency":"USD","unitRateINR":"181540.6","date":"30-Oct-2024","totalValueINR":"907703.19","totalValueInUsd":"10802.6","indian_port":"Bombay Air","hs_no":"29052900","bill_no":"6414117","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NEW YORK - JOHN F. K","supplierAddress":"6 COMMERCE DRIVE, DANBURY,CT 06810 SDNF SDNF U.S.A.","customerAddress":"1601 16TH FLR G WING,LOTUS CORPOR"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732300200,"product":"NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OR NADP (CAS NO.53-59-8) (INTERMEDIATE GOODS)","address":"M-34, SAKET,","city":"NEW DELHI,DELHI","supplier":"SYNCOZYMES SHANGHAI CO. ","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"TEVA API","customerCountry":"INDIA","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"1450","totalValueFC":"14665.3","currency":"USD","unitRateINR":"123757.5","date":"23-Nov-2024","totalValueINR":"1237575","totalValueInUsd":"14665.3","indian_port":"Delhi Air","hs_no":"29349990","bill_no":"6843778","productDescription":"Intermediate","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"BUILDING 1, NO.1199 LANDIAN RD., PUDONG NEW AREA, SHANGHAI 201318 P.R. CHINA CHINA","customerAddress":"M-34, SAKET,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732818600,"product":"B-NAD (BETA-NICOTINAMIDE-ADENINE DINUCLEOTIDE, OXIDIZED FORM) (ABBREVIATION) (CAT-44065900) (LOT.008410)(CEPA CERT NO.24","address":"SHOP NO.37,GR,FLR,THE GREAT EASTERN","city":"PLOT NO.20,SEC-4,NERUL, NAVI MUMBAI","supplier":"NISSHIN SEIFUN GROUP","supplierCountry":"JAPAN","foreign_port":"N\/A","customer":"NISSHIN SEIFUN GROUP","customerCountry":"INDIA","quantity":"7.00","actualQuantity":"7000","unit":"GMS","unitRateFc":"78.9","totalValueFC":"6698","currency":"INR","unitRateINR":"80.7","date":"29-Nov-2024","totalValueINR":"565234.68","totalValueInUsd":"6698","indian_port":"Bombay Air","hs_no":"29349990","bill_no":"6966581","productDescription":"API","marketType":"REGULATED MARKET","country":"JAPAN","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"6-10,3-CHROME,AZUSAWA, ITABASHI-KU, TOKYO 174-8505. JAPAN","customerAddress":"SHOP NO.37,GR,FLR,THE GREAT EASTERN"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732818600,"product":"B-NAD (BETA-NICOTINAMIDE-ADENINE DINUCLEOTIDE, OXIDIZED FORM) (ABBREVIATION) (CAT-44065900) (LOT.008411)(CEPA CERT NO.24","address":"SHOP NO.37,GR,FLR,THE GREAT EASTERN","city":"PLOT NO.20,SEC-4,NERUL, NAVI MUMBAI","supplier":"NISSHIN SEIFUN GROUP","supplierCountry":"JAPAN","foreign_port":"N\/A","customer":"NISSHIN SEIFUN GROUP","customerCountry":"INDIA","quantity":"20.00","actualQuantity":"20000","unit":"GMS","unitRateFc":"78.9","totalValueFC":"19137.2","currency":"INR","unitRateINR":"80.7","date":"29-Nov-2024","totalValueINR":"1614956.23","totalValueInUsd":"19137.2","indian_port":"Bombay Air","hs_no":"29349990","bill_no":"6966581","productDescription":"API","marketType":"REGULATED MARKET","country":"JAPAN","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"6-10,3-CHROME,AZUSAWA, ITABASHI-KU, TOKYO 174-8505. JAPAN","customerAddress":"SHOP NO.37,GR,FLR,THE GREAT EASTERN"}]

Number of Transactions

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Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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ABOUT THIS PAGE

Beta Nicotinamide Adenine Dinucleotide Manufacturers

A Beta Nicotinamide Adenine Dinucleotide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Beta Nicotinamide Adenine Dinucleotide, including repackagers and relabelers. The FDA regulates Beta Nicotinamide Adenine Dinucleotide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Beta Nicotinamide Adenine Dinucleotide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Beta Nicotinamide Adenine Dinucleotide manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Beta Nicotinamide Adenine Dinucleotide Suppliers

A Beta Nicotinamide Adenine Dinucleotide supplier is an individual or a company that provides Beta Nicotinamide Adenine Dinucleotide active pharmaceutical ingredient (API) or Beta Nicotinamide Adenine Dinucleotide finished formulations upon request. The Beta Nicotinamide Adenine Dinucleotide suppliers may include Beta Nicotinamide Adenine Dinucleotide API manufacturers, exporters, distributors and traders.

click here to find a list of Beta Nicotinamide Adenine Dinucleotide suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Beta Nicotinamide Adenine Dinucleotide USDMF

A Beta Nicotinamide Adenine Dinucleotide DMF (Drug Master File) is a document detailing the whole manufacturing process of Beta Nicotinamide Adenine Dinucleotide active pharmaceutical ingredient (API) in detail. Different forms of Beta Nicotinamide Adenine Dinucleotide DMFs exist exist since differing nations have different regulations, such as Beta Nicotinamide Adenine Dinucleotide USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Beta Nicotinamide Adenine Dinucleotide DMF submitted to regulatory agencies in the US is known as a USDMF. Beta Nicotinamide Adenine Dinucleotide USDMF includes data on Beta Nicotinamide Adenine Dinucleotide's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Beta Nicotinamide Adenine Dinucleotide USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Beta Nicotinamide Adenine Dinucleotide suppliers with USDMF on PharmaCompass.

Beta Nicotinamide Adenine Dinucleotide NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Beta Nicotinamide Adenine Dinucleotide as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Beta Nicotinamide Adenine Dinucleotide API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Beta Nicotinamide Adenine Dinucleotide as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Beta Nicotinamide Adenine Dinucleotide and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Beta Nicotinamide Adenine Dinucleotide NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Beta Nicotinamide Adenine Dinucleotide suppliers with NDC on PharmaCompass.

Beta Nicotinamide Adenine Dinucleotide GMP

Beta Nicotinamide Adenine Dinucleotide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Beta Nicotinamide Adenine Dinucleotide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Beta Nicotinamide Adenine Dinucleotide GMP manufacturer or Beta Nicotinamide Adenine Dinucleotide GMP API supplier for your needs.

Beta Nicotinamide Adenine Dinucleotide CoA

A Beta Nicotinamide Adenine Dinucleotide CoA (Certificate of Analysis) is a formal document that attests to Beta Nicotinamide Adenine Dinucleotide's compliance with Beta Nicotinamide Adenine Dinucleotide specifications and serves as a tool for batch-level quality control.

Beta Nicotinamide Adenine Dinucleotide CoA mostly includes findings from lab analyses of a specific batch. For each Beta Nicotinamide Adenine Dinucleotide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Beta Nicotinamide Adenine Dinucleotide may be tested according to a variety of international standards, such as European Pharmacopoeia (Beta Nicotinamide Adenine Dinucleotide EP), Beta Nicotinamide Adenine Dinucleotide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Beta Nicotinamide Adenine Dinucleotide USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

Find Beta Nicotinamide Adenine Dinucleotide manufacturers, exporters & distributors on PharmaCompass

Beta Nicotinamide Adenine Dinucleotide

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6 API Suppliers

3 USDMF

8 NDC API

4 Listed Suppliers

$ API Reference Price

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API REF. PRICE (USD/KG)

$ 153