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Chemistry

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Also known as: 138-92-1, Histalog, Ametazole dihydrochloride, 2-(3-pyrazolyl)ethanamine dihydrochloride, Betazole hcl, Betazole (dihydrochloride)
Molecular Formula
C5H11Cl2N3
Molecular Weight
184.06  g/mol
InChI Key
BUXCUOWXTOKEMQ-UHFFFAOYSA-N
FDA UNII
66ABP6C83F

Betazole
A histamine H2 agonist used clinically to test gastric secretory function.
1 2D Structure

Betazole

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-(1H-pyrazol-5-yl)ethanamine;dihydrochloride
2.1.2 InChI
InChI=1S/C5H9N3.2ClH/c6-3-1-5-2-4-7-8-5;;/h2,4H,1,3,6H2,(H,7,8);2*1H
2.1.3 InChI Key
BUXCUOWXTOKEMQ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=C(NN=C1)CCN.Cl.Cl
2.2 Other Identifiers
2.2.1 UNII
66ABP6C83F
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Ametazole

2. Betazole

3. Betazole Monohydrochloride

4. Dihydrochloride, Betazole

5. Histalog

6. Lilly 96791

7. Monohydrochloride, Betazole

2.3.2 Depositor-Supplied Synonyms

1. 138-92-1

2. Histalog

3. Ametazole Dihydrochloride

4. 2-(3-pyrazolyl)ethanamine Dihydrochloride

5. Betazole Hcl

6. Betazole (dihydrochloride)

7. 3-(2-aminoethyl)pyrazole Dihydrochloride

8. 3-beta-aminoethylpyrazole Dihydrochloride

9. 1h-pyrazole-3-ethanamine, Dihydrochloride

10. 2-(3-pyrazolyl)ethylamine Dihydrochloride

11. 2-(1h-pyrazol-3-yl)-ethylamine Dihydrochloride

12. [2-(1h-pyrazol-3-yl)ethyl]amine Dihydrochloride

13. 66abp6c83f

14. 2-(1h-pyrazol-5-yl)ethanamine;dihydrochloride

15. Mfcd01693704

16. Gastramine

17. Histimin

18. 2-(1h-pyrazol-3-yl)ethanamine Dihydrochloride

19. Betazole Hydrochloride (jan)

20. Betazole Hydrochloride [jan]

21. Einecs 205-345-2

22. Unii-66abp6c83f

23. 1h-pyrazole-3-ethanamine Dihydrochloride

24. 3,5-beta-pyrazoleethylamine Dihydrochloride

25. Betazole Hydrochloride [usp:jan]

26. Histalog (tn)

27. Betazoldihydrochlorid

28. Pyrazole, 3-(2-aminoethyl)-, Dihydrochloride

29. 2-(1h-pyrazol-5-yl)ethanamine Dihydrochloride

30. Schembl1237744

31. Chembl4303510

32. Chebi:31280

33. Hy-b1557a

34. Ac1362

35. Betazole Dihydrochloride [mi]

36. Akos027321706

37. Betazole Hydrochloride [who-dd]

38. Ccg-220043

39. Nsc 759872

40. Sb33227

41. 2-(3-pyrazolyl)ethanamine 2hcl

42. 2-(3-pyrazolyl)ethanaminedihydrochloride

43. Cs-12207

44. Sy040011

45. Betazole Hydrochloride [orange Book]

46. Db-124560

47. Cs-0013439

48. S6612

49. D01187

50. 2-(1h-pyrazol-3-yl)ethan-1-amine Dihydrochloride

51. Sr-01000841815

52. Sr-01000841815-2

53. 3-(2-aminoethyl)pyrazole Dihydrochloride (6ci,8ci)

54. Q27114259

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 184.06 g/mol
Molecular Formula C5H11Cl2N3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass183.0330028 g/mol
Monoisotopic Mass183.0330028 g/mol
Topological Polar Surface Area54.7 Ų
Heavy Atom Count10
Formal Charge0
Complexity64.7
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Histamine Agonists

Drugs that bind to and activate histamine receptors. Although they have been suggested for a variety of clinical applications histamine agonists have so far been more widely used in research than therapeutically. (See all compounds classified as Histamine Agonists.)


Gastrointestinal Agents

Drugs used for their effects on the gastrointestinal system, as to control gastric acidity, regulate gastrointestinal motility and water flow, and improve digestion. (See all compounds classified as Gastrointestinal Agents.)


ABOUT THIS PAGE

Betazole Manufacturers

A Betazole manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Betazole, including repackagers and relabelers. The FDA regulates Betazole manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Betazole API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Betazole Suppliers

A Betazole supplier is an individual or a company that provides Betazole active pharmaceutical ingredient (API) or Betazole finished formulations upon request. The Betazole suppliers may include Betazole API manufacturers, exporters, distributors and traders.

Betazole GMP

Betazole Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Betazole GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Betazole GMP manufacturer or Betazole GMP API supplier for your needs.

Betazole CoA

A Betazole CoA (Certificate of Analysis) is a formal document that attests to Betazole's compliance with Betazole specifications and serves as a tool for batch-level quality control.

Betazole CoA mostly includes findings from lab analyses of a specific batch. For each Betazole CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Betazole may be tested according to a variety of international standards, such as European Pharmacopoeia (Betazole EP), Betazole JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Betazole USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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