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Chemistry

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Also known as: 138-92-1, Histalog, Ametazole dihydrochloride, 2-(3-pyrazolyl)ethanamine dihydrochloride, Betazole hcl, Betazole (dihydrochloride)
Molecular Formula
C5H11Cl2N3
Molecular Weight
184.06  g/mol
InChI Key
BUXCUOWXTOKEMQ-UHFFFAOYSA-N
FDA UNII
66ABP6C83F

Betazole
A histamine H2 agonist used clinically to test gastric secretory function.
1 2D Structure

Betazole

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-(1H-pyrazol-5-yl)ethanamine;dihydrochloride
2.1.2 InChI
InChI=1S/C5H9N3.2ClH/c6-3-1-5-2-4-7-8-5;;/h2,4H,1,3,6H2,(H,7,8);2*1H
2.1.3 InChI Key
BUXCUOWXTOKEMQ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=C(NN=C1)CCN.Cl.Cl
2.2 Other Identifiers
2.2.1 UNII
66ABP6C83F
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Ametazole

2. Betazole

3. Betazole Monohydrochloride

4. Dihydrochloride, Betazole

5. Histalog

6. Lilly 96791

7. Monohydrochloride, Betazole

2.3.2 Depositor-Supplied Synonyms

1. 138-92-1

2. Histalog

3. Ametazole Dihydrochloride

4. 2-(3-pyrazolyl)ethanamine Dihydrochloride

5. Betazole Hcl

6. Betazole (dihydrochloride)

7. 3-(2-aminoethyl)pyrazole Dihydrochloride

8. 3-beta-aminoethylpyrazole Dihydrochloride

9. 1h-pyrazole-3-ethanamine, Dihydrochloride

10. 2-(3-pyrazolyl)ethylamine Dihydrochloride

11. 2-(1h-pyrazol-3-yl)-ethylamine Dihydrochloride

12. [2-(1h-pyrazol-3-yl)ethyl]amine Dihydrochloride

13. 66abp6c83f

14. 2-(1h-pyrazol-5-yl)ethanamine;dihydrochloride

15. Mfcd01693704

16. Gastramine

17. Histimin

18. 2-(1h-pyrazol-3-yl)ethanamine Dihydrochloride

19. Betazole Hydrochloride (jan)

20. Betazole Hydrochloride [jan]

21. Einecs 205-345-2

22. Unii-66abp6c83f

23. 1h-pyrazole-3-ethanamine Dihydrochloride

24. 3,5-beta-pyrazoleethylamine Dihydrochloride

25. Betazole Hydrochloride [usp:jan]

26. Histalog (tn)

27. Betazoldihydrochlorid

28. Pyrazole, 3-(2-aminoethyl)-, Dihydrochloride

29. 2-(1h-pyrazol-5-yl)ethanamine Dihydrochloride

30. Schembl1237744

31. Chembl4303510

32. Chebi:31280

33. Hy-b1557a

34. Ac1362

35. Betazole Dihydrochloride [mi]

36. Akos027321706

37. Betazole Hydrochloride [who-dd]

38. Ccg-220043

39. Nsc 759872

40. Sb33227

41. 2-(3-pyrazolyl)ethanamine 2hcl

42. 2-(3-pyrazolyl)ethanaminedihydrochloride

43. Cs-12207

44. Sy040011

45. Betazole Hydrochloride [orange Book]

46. Db-124560

47. Cs-0013439

48. S6612

49. D01187

50. 2-(1h-pyrazol-3-yl)ethan-1-amine Dihydrochloride

51. Sr-01000841815

52. Sr-01000841815-2

53. 3-(2-aminoethyl)pyrazole Dihydrochloride (6ci,8ci)

54. Q27114259

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 184.06 g/mol
Molecular Formula C5H11Cl2N3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass183.0330028 g/mol
Monoisotopic Mass183.0330028 g/mol
Topological Polar Surface Area54.7 Ų
Heavy Atom Count10
Formal Charge0
Complexity64.7
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Histamine Agonists

Drugs that bind to and activate histamine receptors. Although they have been suggested for a variety of clinical applications histamine agonists have so far been more widely used in research than therapeutically. (See all compounds classified as Histamine Agonists.)


Gastrointestinal Agents

Drugs used for their effects on the gastrointestinal system, as to control gastric acidity, regulate gastrointestinal motility and water flow, and improve digestion. (See all compounds classified as Gastrointestinal Agents.)


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