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Bethanechol

DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

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ACTIVE PHARMA INGREDIENTS

13 API Suppliers, 7 USDMF, 2 JDMF, 3 EU WC, 1 KDMF, 3 NDC API, 4 Listed Suppliers, $ API Reference Price

13 API Suppliers
7 USDMF
2 JDMF
3 EU WC
1 KDMF
3 NDC API
4 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

85 FDF Dossiers, 78 FDA Orange Book, 6 Canada, 1 Australia

85 FDF Dossiers
78 FDA Orange Book
6 Canada
1 Australia

DRUG PRODUCT COMPOSITIONS

TABLET;ORAL - 10MG, TABLET;ORAL - 25MG

drugProductComposition
TABLET;ORAL - 10MG
TABLET;ORAL - 25MG

RELATED EXCIPIENT COMPANIES

1 SPI Pharma, 1 DKSH, 3 Faran Shimi Pharmaceutical, 1 Boai NKY Pharmaceuticals Ltd, 10 Gangwal Healthcare, 1 Nanjing Well Pharmaceutical, 1 Aeon Procare, 4 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 9 BASF, 6 DFE Pharma, 6 Gangwal Chemicals, 1 Ideal Cures Pvt Ltd, 1 Ingredion Pharma Solutions, 23 Kerry, 11 Microlex e.U, 1 Novo Excipients, 3 Pharmatrans-Sanaq, 3 Pluviaendo, 3 Prachin Chemical, 9 Roquette, 2 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 11 Sigachi Industries, 3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

51 Fillers, Diluents & Binders, 25 Direct Compression, 15 Granulation, 15 Disintegrants & Superdisintegrants, 14 Lubricants & Glidants, 13 Thickeners and Stabilizers, 13 Co-Processed Excipients, 8 Controlled & Modified Release, 6 Solubilizers, 4 Coating Systems & Additives, 3 Emulsifying Agents, 3 Parenteral, 3 Film Formers & Plasticizers, 2 Chewable & Orodispersible Aids, 2 Taste Masking, 1 Rheology Modifiers, 1 API Stability Enhancers

excipientsByApplications
51 Fillers, Diluents & Binders
25 Direct Compression
15 Granulation
15 Disintegrants & Superdisintegrants
14 Lubricants & Glidants
13 Thickeners and Stabilizers
13 Co-Processed Excipients
8 Controlled & Modified Release
6 Solubilizers
4 Coating Systems & Additives
3 Emulsifying Agents
3 Parenteral
3 Film Formers & Plasticizers
2 Chewable & Orodispersible Aids
2 Taste Masking
1 Rheology Modifiers
1 API Stability Enhancers

DIGITAL CONTENT

2 NEWS #PharmaBuzz

media
2 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 9 Finished Drug Prices

globalSalesInformation
1 US Medicaid Prescriptions
9 Finished Drug Prices

MARKET PLACE

4 APIs, 1 FDF Dossiers

marketPlace
4 APIs
1 FDF Dossiers

REF. STANDARDS & IMPURITIES

1 USP , 1 Others

otherSolutions
1 USP
1 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 688

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

13,068,847

Annual Reports (USD Million)

Finished Drug Prices

114 RELATED EXCIPIENT COMPANIES

179EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 590-63-6, Urecholine, Duvoid, Myocholine, Besacholine, Myotonachol

Molecular Formula

C₇H₁₇ClN₂O₂

Molecular Weight

196.67 g/mol

InChI Key

XXRMYXBSBOVVBH-UHFFFAOYSA-N

FDA UNII

H4QBZ2LO84

A slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, HEART RATE changes, and BRONCHIAL SPASM.

1 2D Structure

Bethanechol

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-carbamoyloxypropyl(trimethyl)azanium;chloride

2.1.2 InChI

InChI=1S/C7H16N2O2.ClH/c1-6(11-7(8)10)5-9(2,3)4;/h6H,5H2,1-4H3,(H-,8,10);1H

2.1.3 InChI Key

XXRMYXBSBOVVBH-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC(C[N+](C)(C)C)OC(=O)N.[Cl-]

2.2 Other Identifiers

2.2.1 UNII

H4QBZ2LO84

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Bethanechol

2. Bethanecol

3. Chloride, Bethanechol

4. Duvoid

5. Hermes, Myo

6. Myo Hermes

7. Myocholine

8. Myotonachol

9. Myotonine

10. Pms Bethanechol Chloride

11. Pms-bethanechol Chloride

12. Urecholine

13. Urocarb

2.3.2 Depositor-Supplied Synonyms

1. 590-63-6

2. Urecholine

3. Duvoid

4. Myocholine

5. Besacholine

6. Myotonachol

7. Carbamyl-beta-methylcholine Chloride

8. Mechotane

9. Mechothane

10. Mecothane

11. Mictone

12. Mictrol

13. Bethanechol (chloride)

14. Uro-carb

15. Urecholine Chloride

16. Carbamylmethylcholine Chloride

17. Bethaine Choline Chloride

18. 2-carbamoyloxypropyltrimethylammonium Chloride

19. Trimethyl(2-carbamoyloxypropyl)ammonium Chloride

20. 2-(carbamoyloxy)-n,n,n-trimethylpropan-1-aminium Chloride

21. (2-hydroxypropyl)trimethylammonium Chloride Carbamate

22. 2-(carbamoyloxy)-n,n,n-trimethyl-1-propanaminium Chloride

23. Beta-methyl Carbachol Chloride

24. Nsc-30783

25. 2-((aminocarbonyl)oxy)-n,n,n-trimethyl-1-propanaminium Chloride

26. 1-propanaminium, 2-[(aminocarbonyl)oxy]-n,n,n-trimethyl-, Chloride

27. H4qbz2lo84

28. Mls000028675

29. Chebi:3085

30. Myotonine

31. 2-carbamoyloxypropyl(trimethyl)azanium;chloride

32. Muscaran

33. Smr000058680

34. 1-propanaminium, 2-((aminocarbonyl)oxy)-n,n,n-trimethyl-, Chloride

35. Dsstox_cid_2676

36. Mfcd00055224

37. (2-carbamoyloxypropyl)trimethylammonium Chloride

38. Dsstox_rid_76686

39. Dsstox_gsid_22676

40. Myotonine Chloride

41. Beta-methylcholine Chloride Urethan

42. Sr-01000000282

43. Ncgc00163217-01

44. Einecs 209-686-8

45. Nsc 30783

46. Unii-h4qbz2lo84

47. Carbaminoyl, Beta-methylcholine Chloride

48. 1-propanaminium, 2-((aminocarbonyl)oxy)-n,n,n-trimethyl-, Chloride (1:1)

49. 1-propanaminium, 2-[(aminocarbonyl)oxy]-n,n,n-trimethyl-, Chloride (1:1)

50. Carbamyl-

51. A-methylcholine Chloride

52. Urecholine (tn)

53. Bethanechol Chloride [usp:ban:jan]

54. Regid855684

55. Opera_id_1125

56. Cas-590-63-6

57. Chembl1768

58. Schembl37393

59. Ammonium, Chloride, Carbamate

60. Mls001148071

61. Mls006011984

62. Spectrum1500146

63. Dtxsid2022676

64. .beta.-methyl Carbachol Chloride

65. Hms500i21

66. Hy-b0406a

67. (+-)-(2-hydroxypropyl)trimethylammonium Chloride Carbamate

68. Bethanechol Chloride [mi]

69. Carbamyl-ss-methylcholine Chloride

70. Bethanechol Chloride (jp17/usp)

71. Bethanechol Chloride [jan]

72. Hms1571g08

73. Hms1920g19

74. Hms2091m19

75. Hms2098g08

76. Hms2232d09

77. Hms3259l15

78. Hms3260n10

79. Hms3374d01

80. Hms3656g21

81. Hms3715g08

82. Hms3884h19

83. Pharmakon1600-01500146

84. Nsc30783

85. Bethanechol Chloride [vandf]

86. Tox21_112028

87. Tox21_500304

88. Ammonium, (2-hydroxypropyl)trimethyl-, Chloride, Carbamate

89. Bethanechol Chloride [mart.]

90. Ccg-38936

91. Nsc755913

92. S2455

93. .beta.-methylcholine Chloride Urethan

94. Bethanechol Chloride [usp-rs]

95. Bethanechol Chloride [who-dd]

96. 1-propanaminium, 2-((aminocarbonyl)oxy)-n,n,n-trimethyl-, Chloride, (+-)-

97. Akos006230324

98. Carbamyl- Beta -methylcholine Chloride

99. Tox21_112028_1

100. Carbamyl-beta-methylcholine Chloride.cd

101. Lp00304

102. Nc00660

103. Nsc-755913

104. Ncgc00015245-10

105. Ncgc00093753-01

106. Ncgc00093753-02

107. Ncgc00093753-03

108. Ncgc00093753-04

109. Ncgc00093753-05

110. Ncgc00260989-01

111. ( Inverted Exclamation Marka)-bethanechol

112. As-13371

113. Bethanechol Chloride [orange Book]

114. Carbaminoyl, .beta.-methylcholine Chloride

115. Wln: Zvoy1&1k1&1&1 &q &g

116. Bethanechol Chloride [usp Monograph]

117. Carbamyl-b-methylcholinechloride*crystalline

118. Eu-0100304

119. Ft-0622944

120. Ft-0663092

121. Ft-0663093

122. Sw197254-3

123. En300-51035

124. C 5259

125. C08202

126. D01000

127. F20466

128. A832139

129. Sr-01000000282-2

130. Sr-01000000282-4

131. Sr-01000000282-7

132. Q27105939

133. (+/-)-(2-hydroxypropyl)trimethylammonium Chloride Carbamate

134. 2-[(aminocarbonyl)oxy]-n,n,n-trimethylpropan-1-aminium Chloride

135. 1-propanaminium, 2-((aminocarbonyl)oxy)-n,n,n-trimethyl-, Chloride, (+/-)-

136. 2-carbamoyloxypropyl(trimethyl)ammonium Chloride;2-(carbamoyloxy)-n,n,n-trimethyl-1-propanaminium Chloride

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₇H₁₇ClN₂O₂
Molecular Weight	196.67 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Exact Mass	196.0978555 g/mol
Monoisotopic Mass	196.0978555 g/mol
Topological Polar Surface Area	52.3 Å²
Heavy Atom Count	12
Formal Charge	0
Complexity	140
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 4
Drug Name	Bethanechol chloride
Drug Label	Bethanechol chloride, a cholinergic agent, is a synthetic ester which is structurally and pharmacologically related to acetylcholine.It is designated chemically as 2-[(aminocarbonyl)oxy]-N, N, N-trimethyl-1-propanaminium chloride. Its molecular formu...
Active Ingredient	Bethanechol chloride
Dosage Form	Tablet
Route	oral; Oral
Strength	5mg; 25mg; 50mg; 10mg
Market Status	Prescription
Company	Emcure Usa; Wockhardt; Upsher Smith; Amneal Pharm; Lannett; Sun Pharm Inds; Pharmax; Impax Labs

2 of 4
Drug Name	Urecholine
PubMed Health	Bethanechol
Drug Classes	Cholinergic, Urinary Antispasmodic
Active Ingredient	Bethanechol chloride
Dosage Form	Tablet
Route	Oral
Strength	25mg; 5mg; 50mg; 10mg
Market Status	Prescription
Company	Odyssey Pharms

3 of 4
Drug Name	Bethanechol chloride
Drug Label	Bethanechol chloride, a cholinergic agent, is a synthetic ester which is structurally and pharmacologically related to acetylcholine.It is designated chemically as 2-[(aminocarbonyl)oxy]-N, N, N-trimethyl-1-propanaminium chloride. Its molecular formu...
Active Ingredient	Bethanechol chloride
Dosage Form	Tablet
Route	oral; Oral
Strength	5mg; 25mg; 50mg; 10mg
Market Status	Prescription
Company	Emcure Usa; Wockhardt; Upsher Smith; Amneal Pharm; Lannett; Sun Pharm Inds; Pharmax; Impax Labs

4 of 4
Drug Name	Urecholine
PubMed Health	Bethanechol
Drug Classes	Cholinergic, Urinary Antispasmodic
Active Ingredient	Bethanechol chloride
Dosage Form	Tablet
Route	Oral
Strength	25mg; 5mg; 50mg; 10mg
Market Status	Prescription
Company	Odyssey Pharms

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Muscarinic Agonists

Drugs that bind to and activate muscarinic cholinergic receptors (RECEPTORS, MUSCARINIC). Muscarinic agonists are most commonly used when it is desirable to increase smooth muscle tone, especially in the GI tract, urinary bladder and the eye. They may also be used to reduce heart rate. (See all compounds classified as Muscarinic Agonists.)

Parasympathomimetics

Drugs that mimic the effects of parasympathetic nervous system activity. Included here are drugs that directly stimulate muscarinic receptors and drugs that potentiate cholinergic activity, usually by slowing the breakdown of acetylcholine (CHOLINESTERASE INHIBITORS). Drugs that stimulate both sympathetic and parasympathetic postganglionic neurons (GANGLIONIC STIMULANTS) are not included here. (See all compounds classified as Parasympathomimetics.)

5.2 FDA Pharmacological Classification

5.2.1 Pharmacological Classes

Cholinergic Muscarinic Agonists [MoA]; Cholinergic Muscarinic Agonist [EPC]

API SUPPLIERS

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

USDMF

01

Corden Pharma Bergamo Spa

Italy

AES 2024

Not Confirmed

02

Seratec Sas

France

AES 2024

Not Confirmed

03

Siegfried Evionnaz Sa

Switzerland

AES 2024

Not Confirmed

04

Wockhardt Ltd

India

AES 2024

Not Confirmed

05

Ck Fine Chemicals Inc

Country

AES 2024

Not Confirmed

06

Ganes Chemicals Inc Pennsville Div

Country

AES 2024

Not Confirmed

07

Ganes Chemicals Inc Pennsville Div

Country

AES 2024

Not Confirmed

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

JDMF

01

Permakem Asia Co., Ltd.

Japan

AES 2024

Not Confirmed

02

Permakem Asia Co., Ltd.

Japan

AES 2024

Not Confirmed

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

EU WC

01

Medigraph Pharmaceuticals Pvt. Ltd.

India

AES 2024

Not Confirmed

02

Medigraph Pharmaceuticals Pvt. Ltd.

India

AES 2024

Not Confirmed

03

Wockhardt

India

AES 2024

Not Confirmed

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

KDMF

01

Samjin pharm Co. Ltd

South Korea

AES 2024

Not Confirmed

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

NDC API

01

AX Pharmaceutical Corp

Canada

AES 2024

Not Confirmed

02

Seratec S.A.S.

France

AES 2024

Not Confirmed

03

Siegfried Evionnaz SA

Switzerland

AES 2024

Not Confirmed

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Listed Suppliers

01

Globofarm International

India

AES 2024

Not Confirmed

02

JRC

India

AES 2024

Not Confirmed

03

Siegfried AG

Switzerland

AES 2024

Not Confirmed

04

Wockhardt

India

AES 2024

Not Confirmed

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

API Reference Price

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NO.37","city":"BOMBAY ,MAHARASHTRA","supplier":"TRICON ENTERPRISES PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"TAIPEI","customer":"TO THE ORDER OF","customerCountry":"TAIWAN","quantity":"13.00","actualQuantity":"13","unit":"KGS","unitRateFc":"480","totalValueFC":"6157","currency":"USD","unitRateINR":39297.923076923078,"date":"29-Feb-2024","totalValueINR":"510873","totalValueInUsd":"6157","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"7951386","productDescription":"API","marketType":"REGULATED MARKET","country":"TAIWAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"KAMALA BHUVAN NO.2, 1ST FLR. 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