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    Chemistry

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    Also known as: 1235-82-1, Akineton, Akinophyl, Biperiden hcl, Biperiden (hydrochloride), Akineton hydrochloride
    Molecular Formula
    C21H30ClNO
    Molecular Weight
    347.9  g/mol
    InChI Key
    RDNLAULGBSQZMP-UHFFFAOYSA-N
    FDA UNII
    K35N76CUHF
    Biperiden Hydrochloride
    A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
    1 2D Structure

    Biperiden Hydrochloride

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    1-(2-bicyclo[2.2.1]hept-5-enyl)-1-phenyl-3-piperidin-1-ylpropan-1-ol;hydrochloride
    2.1.2 InChI
    InChI=1S/C21H29NO.ClH/c23-21(19-7-3-1-4-8-19,11-14-22-12-5-2-6-13-22)20-16-17-9-10-18(20)15-17;/h1,3-4,7-10,17-18,20,23H,2,5-6,11-16H2;1H
    2.1.3 InChI Key
    RDNLAULGBSQZMP-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1CCN(CC1)CCC(C2CC3CC2C=C3)(C4=CC=CC=C4)O.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    K35N76CUHF
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Akineton

    2. Alpha-bicyclo(2.2.1)hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol

    3. Biperiden

    4. Biperiden, 1r-(1 Alpha,2 Alpha(r*),4 Alpha)-isomer

    5. Biperiden, 1s-(1 Alpha,2 Alpha(r*),4 Alpha)-isomer

    6. Biperidene

    7. Hydrochloride, Biperiden

    2.3.2 Depositor-Supplied Synonyms

    1. 1235-82-1

    2. Akineton

    3. Akinophyl

    4. Biperiden Hcl

    5. Biperiden (hydrochloride)

    6. Akineton Hydrochloride

    7. Biperidine Hydrochloride

    8. Tasmolin

    9. Kl 373 (hydrochloride)

    10. Biperidene Hydrochloride

    11. Nsc-84989

    12. Nsc-170950

    13. K35n76cuhf

    14. 1-bicycloheptenyl-1-phenyl-3-piperidinopropanol-1 Hydrochloride

    15. Tasmolin (tn)

    16. 1-(2-bicyclo[2.2.1]hept-5-enyl)-1-phenyl-3-piperidin-1-ylpropan-1-ol;hydrochloride

    17. Dsstox_cid_27832

    18. Dsstox_rid_82595

    19. Dsstox_gsid_47856

    20. 1-piperidinepropanol, Alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-, Hydrochloride (1:1)

    21. Akineton, Hydrochloride

    22. Chebi:59171

    23. Smr001456154

    24. Wln: L55 A Cutj Fxqr&2- At6ntj &gh

    25. Ncgc00182965-01

    26. Einecs 214-976-2

    27. Nsc 84989

    28. Unii-k35n76cuhf

    29. Nsc 170950

    30. Sr-05000001649

    31. .alpha.-5-norbornen-2-yl-.alpha.-phenyl-piperidinepropanol Hydrochloride

    32. .alpha.-[bicyclo[2.2.1]hept-5-en-2-yl]-.alpha.-phenyl-1-piperidinepropanol Hydrochloride

    33. Prestwick_839

    34. Biperiden Hydrochloride [usp:ban:jan]

    35. Biperideni Hydrochloridum

    36. 1-piperidinepropanol, .alpha.-bicyclo(2.2.1)hept-5-en-2-yl-.alpha.-phenyl-, Hydrochloride

    37. Alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropanol Hydrochloride

    38. Cas-1235-82-1

    39. 1-piperidinepropanol, Alpha-bicyclo(2.2.1)hept-5-en-2-yl-alpha-phenyl-, Hydrochloride

    40. Alpha-(bicyclo(2.2.1)hept-5-en-2-yl)-alpha-phenyl-1-piperidinepropanol Hydrochloride

    41. Piperidinepropanol, Alpha-bicyclo(2.2.1)hept-5-en-2-yl-alpha-phenyl-, Hydrochloride

    42. Schembl40776

    43. Mls003915621

    44. Mls006011163

    45. Chembl1201035

    46. Dtxsid2047856

    47. Hms1569f05

    48. Nsc84989

    49. Biperiden Hydrochloride [mi]

    50. Tox21_112785

    51. Tox21_113064

    52. Tox21_500217

    53. Biperiden Hydrochloride (jp17/usp)

    54. Biperiden Hydrochloride [jan]

    55. Nsc170950

    56. 1-piperidinepropanol, Alpha-5-norbornen-2-yl-alpha-phenyl-, Hydrochloride

    57. Akos024457314

    58. Tox21_112785_1

    59. Bcp9000415

    60. Biperiden Hydrochloride [mart.]

    61. Biperiden Hydrochloride [vandf]

    62. Ccg-221521

    63. Cs-0442

    64. Lp00217

    65. 1-(5-bicyclo[2.2.1]hept-2-enyl)-1-phenyl-3-(1-piperidinyl)propan-1-ol Hydrochloride

    66. Biperiden Hydrochloride [who-dd]

    67. Biperiden Hydrochloride [who-ip]

    68. Ncgc00182965-05

    69. Ncgc00260902-01

    70. Hy-13204

    71. Biperiden Hydrochloride [orange Book]

    72. Sw196970-2

    73. Biperiden Hydrochloride [ep Monograph]

    74. Biperiden Hydrochloride [usp Impurity]

    75. D02246

    76. Biperiden Hydrochloride, >=98% (hplc), Powder

    77. Biperideni Hydrochloridum [who-ip Latin]

    78. J-004957

    79. Sr-05000001649-3

    80. Q27126508

    81. 1-bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-ylpropan-1-ol Hcl

    82. .alpha.-5-norbornen-2-yl-.alpha.-phenyl-1-piperidinepropanol Hydrochloride

    83. 1-(bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-(piperidin-1-yl)propan-1-olhydrochloride

    2.4 Create Date
    2005-03-27
    3 Chemical and Physical Properties
    Molecular Weight 347.9 g/mol
    Molecular Formula C21H30ClNO
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count5
    Exact Mass347.2015923 g/mol
    Monoisotopic Mass347.2015923 g/mol
    Topological Polar Surface Area23.5 Ų
    Heavy Atom Count24
    Formal Charge0
    Complexity422
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count4
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Antiparkinson Agents

    Agents used in the treatment of Parkinson's disease. The most commonly used drugs act on the dopaminergic system in the striatum and basal ganglia or are centrally acting muscarinic antagonists. (See all compounds classified as Antiparkinson Agents.)

    Muscarinic Antagonists

    Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system. (See all compounds classified as Muscarinic Antagonists.)

    Parasympatholytics

    Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS. (See all compounds classified as Parasympatholytics.)

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    27-Jan-2021
    26-Jul-2024
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    Biperiden Hydrochloride Manufacturers | Traders | Suppliers

    Biperiden Hydrochloride Manufacturers, Traders, Suppliers 1
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    We have 3 companies offering Biperiden Hydrochloride

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    1. CF Pharma
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    3. API Corporation
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