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Biperiden Lactate

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ACTIVE PHARMA INGREDIENTS

3 API Suppliers, 3 Listed Suppliers, $ API Reference Price

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$ API Reference Price

FINISHED DOSAGE FORMULATIONS

4 FDF Dossiers, 1 FDA Orange Book, 1 Europe, 2 Listed Dossiers

4 FDF Dossiers
1 FDA Orange Book
1 Europe
2 Listed Dossiers

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3 APIs

CF Pharma biperiden lactate

Synopsis

ACTIVE PHARMA INGREDIENTS

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API REF. PRICE (USD/KG)

$ 23,447

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Chemistry

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Also known as: Akineton, 09td6c5147, 1-piperidinepropanol, alpha-bicyclo(2.2.1)hept-5-en-2-yl-alpha-phenyl-, compd. with 2-hydroxypropanoic acid (1:1), Tasmolin (tn), Akineton lactate, Einecs 230-388-9

Molecular Formula

C₂₄H₃₅NO₄

Molecular Weight

401.5 g/mol

InChI Key

GLPUBCPQWZZFNJ-UHFFFAOYSA-N

FDA UNII

09TD6C5147

1 2D Structure

Biperiden Lactate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-(2-bicyclo[2.2.1]hept-5-enyl)-1-phenyl-3-piperidin-1-ylpropan-1-ol;2-hydroxypropanoic acid

2.1.2 InChI

InChI=1S/C21H29NO.C3H6O3/c23-21(19-7-3-1-4-8-19,11-14-22-12-5-2-6-13-22)20-16-17-9-10-18(20)15-17;1-2(4)3(5)6/h1,3-4,7-10,17-18,20,23H,2,5-6,11-16H2;2,4H,1H3,(H,5,6)

2.1.3 InChI Key

GLPUBCPQWZZFNJ-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC(C(=O)O)O.C1CCN(CC1)CCC(C2CC3CC2C=C3)(C4=CC=CC=C4)O

2.2 Other Identifiers

2.2.1 UNII

09TD6C5147

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Biperidene Lactate

2.3.2 Depositor-Supplied Synonyms

1. Akineton

2. 09td6c5147

3. 1-piperidinepropanol, Alpha-bicyclo(2.2.1)hept-5-en-2-yl-alpha-phenyl-, Compd. With 2-hydroxypropanoic Acid (1:1)

4. Tasmolin (tn)

5. Akineton Lactate

6. Einecs 230-388-9

7. Biperidenlactat

8. Unii-09td6c5147

9. Biperiden Lactate [usp:ban:jan]

10. Biperidenlactate

11. Alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropanol Lactate (salt)

12. Alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropanol Compd. With Lactic Acid (1:1)

13. Schembl41834

14. Biperiden Lactate (jan/usp)

15. Biperiden Lactate [jan]

16. Chembl1201067

17. Biperiden Lactate [vandf]

18. Dtxsid40991120

19. Biperiden Lactate [mart.]

20. Biperiden Lactate [who-dd]

21. Hy-13204b

22. Biperiden Lactate [orange Book]

23. Biperiden Lactate [usp Impurity]

24. Lactic Acid, Compd. With Alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropanol (1:1)

25. Lactic Acid, Compound With Alpha-bicyclo(2.2.1)hept-5-en-2-yl-alpha-phenylpiperidin-1-propanol (1:1)

26. Cs-0030940

27. D02247

28. Q27236503

29. .alpha.-5-norbornen-2-yl-.alpha.-phenyl-1-piperidinepropanol Lactate (salt)

30. 1-(2-bicyclo[2.2.1]hept-5-enyl)-1-phenyl-3-piperidin-1-ylpropan-1-ol;2-hydroxypropanoic Acid

31. 1-piperidinepropanol, .alpha.-bicyclo(2.2.1)hept-5-en-2-yl-.alpha.-phenyl-, Compd. With 2-hydroxypropanoic Acid (1:1)

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₂₄H₃₅NO₄
Molecular Weight	401.5 g/mol
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	6
Exact Mass	401.25660860 g/mol
Monoisotopic Mass	401.25660860 g/mol
Topological Polar Surface Area	81 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	481
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	5
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Muscarinic Antagonists

Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system. (See all compounds classified as Muscarinic Antagonists.)

Antiparkinson Agents

Agents used in the treatment of Parkinson's disease. The most commonly used drugs act on the dopaminergic system in the striatum and basal ganglia or are centrally acting muscarinic antagonists. (See all compounds classified as Antiparkinson Agents.)

Parasympatholytics

Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS. (See all compounds classified as Parasympatholytics.)

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API Reference Price

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