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Chemistry

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Also known as: 33171-05-0, 24939-16-0, Curcumin iii, Didemethoxycurcumin, (1e,6e)-1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione, Bis(4-hydroxycinnamoyl)methane
Molecular Formula
C19H16O4
Molecular Weight
308.3  g/mol
InChI Key
PREBVFJICNPEKM-YDWXAUTNSA-N
FDA UNII
2EFO1BP34R

Bisdemethoxycurcumin
bisdemethoxycurcumin is a natural product found in Curcuma amada, Curcuma kwangsiensis, and other organisms with data available.
1 2D Structure

Bisdemethoxycurcumin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(1E,6E)-1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
2.1.2 InChI
InChI=1S/C19H16O4/c20-16-7-1-14(2-8-16)5-11-18(22)13-19(23)12-6-15-3-9-17(21)10-4-15/h1-12,20-21H,13H2/b11-5+,12-6+
2.1.3 InChI Key
PREBVFJICNPEKM-YDWXAUTNSA-N
2.1.4 Canonical SMILES
C1=CC(=CC=C1C=CC(=O)CC(=O)C=CC2=CC=C(C=C2)O)O
2.1.5 Isomeric SMILES
C1=CC(=CC=C1/C=C/C(=O)CC(=O)/C=C/C2=CC=C(C=C2)O)O
2.2 Other Identifiers
2.2.1 UNII
2EFO1BP34R
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1,6-heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-

2. Bis(4-hydroxycinnamoyl)methane

3. Bisdemethoxy-curcumin

2.3.2 Depositor-Supplied Synonyms

1. 33171-05-0

2. 24939-16-0

3. Curcumin Iii

4. Didemethoxycurcumin

5. (1e,6e)-1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione

6. Bis(4-hydroxycinnamoyl)methane

7. Bis-demethoxycurcumin

8. Bisdesmethoxycurcumin

9. Bisdemethoxycucurmin

10. Bis(p-hydroxycinnamoyl)methane

11. (e,e)-bisdemethoxycurcumin

12. 1,6-heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-

13. Nsc687839

14. 2efo1bp34r

15. 1,7-bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione

16. Chembl105350

17. Chebi:71045

18. (1e,6e)-1,7-bis(4-hydroxyphenyl)-hepta-1,6-diene-3,5-dione

19. 1,6-heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (1e,6e)-

20. 1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione

21. 22608-12-4

22. Bhcmt

23. Unii-2efo1bp34r

24. Curcumin Lll

25. Curcuminoid A

26. Bisdemethoxy Curcumin

27. Di-p-coumaroylmethane

28. Dide Methoxycurcu Min

29. Ins No.100(iii)

30. Schembl428638

31. Ins-100(iii)

32. Schembl13521971

33. Cid_5324473

34. Hy-n0007a

35. Dtxsid00872663

36. E-100(iii)

37. Zaa93916

38. Zinc1651126

39. 1,3-di(4-hydroxystyryl)propanedial

40. Bis-demethoxycurcumin [inci]

41. Bdbm50059989

42. Mfcd03419284

43. Bisdesmethoxycurcumin [usp-rs]

44. Akos015902102

45. Ccg-207959

46. Ccg-208635

47. Nsc-687839

48. Bisdemethoxycurcumin, Analytical Standard

49. Ac-24239

50. Ac-34720

51. Adamantan-1-yl-aceticacidhydrazide

52. As-57295

53. As-68737

54. B3347

55. Bisdemethoxycurcumin, >=98% (hplc), Solid

56. Cs-0018287

57. N1712

58. S3938

59. A14544

60. A875406

61. Q-100322

62. Q4917168

63. Brd-k37445107-001-01-9

64. 1,7-bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione(e,e)

65. (1e,6e)-1,7-bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione

66. 1,7-bis(4-hydroxyphenyl)-3-hydroxy-1,3,6-heptatrien-5-one

67. 1,7-bis-(4-hydroxyphenyl)-hepta-1,6-diene-3,5-dione

68. Bisdesmethoxycurcumin (constituent Of Turmeric) [dsc]

69. (1e,6e)-1,7-bis-(4-hydroxy-phenyl)-hepta-1,6-diene-3,5-dione

70. 1,6-heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (e,e)-

71. 5-hydroxy-1,7-bis-(4-hydroxy-phenyl)-hepta-1,4,6-trien-3-one

72. (1e,4z,6e)-5-hydroxy-1,7-bis-(4-hydroxy-phenyl)-hepta-1,4,6-trien-3-one

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 308.3 g/mol
Molecular Formula C19H16O4
XLogP33.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass308.10485899 g/mol
Monoisotopic Mass308.10485899 g/mol
Topological Polar Surface Area74.6 Ų
Heavy Atom Count23
Formal Charge0
Complexity408
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 Metabolism/Metabolites

Bisdemethoxycurcumin has known human metabolites that include Bisdemethoxycurcumin, 4-O-glucuronide.

S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560


ABOUT THIS PAGE

Bisdemethoxycurcumin Manufacturers

A Bisdemethoxycurcumin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Bisdemethoxycurcumin, including repackagers and relabelers. The FDA regulates Bisdemethoxycurcumin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Bisdemethoxycurcumin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Bisdemethoxycurcumin Suppliers

A Bisdemethoxycurcumin supplier is an individual or a company that provides Bisdemethoxycurcumin active pharmaceutical ingredient (API) or Bisdemethoxycurcumin finished formulations upon request. The Bisdemethoxycurcumin suppliers may include Bisdemethoxycurcumin API manufacturers, exporters, distributors and traders.

Bisdemethoxycurcumin GMP

Bisdemethoxycurcumin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Bisdemethoxycurcumin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Bisdemethoxycurcumin GMP manufacturer or Bisdemethoxycurcumin GMP API supplier for your needs.

Bisdemethoxycurcumin CoA

A Bisdemethoxycurcumin CoA (Certificate of Analysis) is a formal document that attests to Bisdemethoxycurcumin's compliance with Bisdemethoxycurcumin specifications and serves as a tool for batch-level quality control.

Bisdemethoxycurcumin CoA mostly includes findings from lab analyses of a specific batch. For each Bisdemethoxycurcumin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Bisdemethoxycurcumin may be tested according to a variety of international standards, such as European Pharmacopoeia (Bisdemethoxycurcumin EP), Bisdemethoxycurcumin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Bisdemethoxycurcumin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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