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    Chemistry

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    Also known as: 22260-51-1, Parlodel, Bromocriptine mesilate, Bromocryptine mesylate, Pravidel, Bromocriptine methanesulfonate
    Molecular Formula
    C33H44BrN5O8S
    Molecular Weight
    750.7  g/mol
    InChI Key
    NOJMTMIRQRDZMT-GSPXQYRGSA-N
    FDA UNII
    FFP983J3OD
    Bromocriptine Mesylate
    A semisynthetic ergotamine alkaloid that is a dopamine D2 agonist. It suppresses prolactin secretion.
    1 2D Structure

    Bromocriptine Mesylate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (6aR,9R)-5-bromo-N-[(1S,2S,4R,7S)-2-hydroxy-7-(2-methylpropyl)-5,8-dioxo-4-propan-2-yl-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide;methanesulfonic acid
    2.1.2 InChI
    InChI=1S/C32H40BrN5O5.CH4O3S/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18;1-5(2,3)4/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39);1H3,(H,2,3,4)/t18-,23-,24+,25+,31-,32+;/m1./s1
    2.1.3 InChI Key
    NOJMTMIRQRDZMT-GSPXQYRGSA-N
    2.1.4 Canonical SMILES
    CC(C)CC1C(=O)N2CCCC2C3(N1C(=O)C(O3)(C(C)C)NC(=O)C4CN(C5CC6=C(NC7=CC=CC(=C67)C5=C4)Br)C)O.CS(=O)(=O)O
    2.1.5 Isomeric SMILES
    CC(C)C[C@H]1C(=O)N2CCC[C@H]2[C@]3(N1C(=O)[C@](O3)(C(C)C)NC(=O)[C@H]4CN([C@@H]5CC6=C(NC7=CC=CC(=C67)C5=C4)Br)C)O.CS(=O)(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    FFP983J3OD
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 2 Bromo Alpha Ergocryptine

    2. 2 Bromo Alpha Ergokryptine

    3. 2 Bromoergocryptine

    4. 2 Bromoergocryptine Mesylate

    5. 2 Bromoergocryptine Methanesulfonate

    6. 2 Bromoergokryptine

    7. 2-bromo-alpha-ergocryptine

    8. 2-bromo-alpha-ergokryptine

    9. 2-bromoergocryptine

    10. 2-bromoergocryptine Mesylate

    11. 2-bromoergocryptine Methanesulfonate

    12. 2-bromoergokryptine

    13. Bromocriptin

    14. Bromocriptine

    15. Bromocryptin

    16. Cb 154

    17. Cb-154

    18. Cb154

    19. Mesylate, 2-bromoergocryptine

    20. Mesylate, Bromocriptine

    21. Methanesulfonate, 2-bromoergocryptine

    22. Parlodel

    2.3.2 Depositor-Supplied Synonyms

    1. 22260-51-1

    2. Parlodel

    3. Bromocriptine Mesilate

    4. Bromocryptine Mesylate

    5. Pravidel

    6. Bromocriptine Methanesulfonate

    7. Cycloset

    8. Bagren

    9. Cb-154 Mesylate

    10. Bromergon

    11. (+)-bromocriptine Methanesulfonate

    12. 2-bromo-alpha-ergocryptine Mesylate

    13. Cb-154

    14. Cb-154 Mesilate

    15. Cb 154

    16. 2-bromoergocryptine Monomethanesulfonate (salt)

    17. Ffp983j3od

    18. Bromocriptine (mesylate)

    19. Chebi:3182

    20. 2-bromoergocryptine Mesylate

    21. Nsc-755915

    22. Oline-9-carboxamide Methanesulfonate

    23. Bromocryptine Methanesulfonate

    24. (5'a)-2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione Mesylate

    25. Bromocriptine Mesylate [usan]

    26. Nsc169774

    27. Sr-01000597796

    28. Einecs 244-881-1

    29. Unii-ffp983j3od

    30. 2-bromo-alpha-ergocryptine Methanesulfonate

    31. Sr-01000075356

    32. 2-bromine-alpha-ergocryptine Methanesulfonate

    33. 2-bromo-alpha-ergokryptine-mesilate [german]

    34. Bromocriptine Mesylate [usan:usp]

    35. Parlodel (tn)

    36. (5'alpha)-2-bromo-12'-hydroxy-5'-(2-methylpropyl)-3',6',18-trioxo-2'-(propan-2-yl)ergotaman Methanesulfonate (salt)

    37. (6ar,9r)-5-bromo-n-[(2r,5s,10as,10bs)-10b-hydroxy-2-(1-methylethyl)-5-(2-methylpropyl)-3,6-dioxooctahydro-8h-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quin

    38. 2-bromo-alpha-ergokryptine-mesilate

    39. Prestwick_771

    40. Cas-22260-51-1

    41. Dsstox_cid_197

    42. Bromocriptinemesylate

    43. Alpha-ergocryptine, 2-bromo-, Methanesulfonate

    44. Dsstox_rid_75426

    45. Dsstox_gsid_20197

    46. Schembl40559

    47. 2-bromo-12'-hydroxy-5'alpha-isobutyl-2'-isopropylergotaman-3',6',18-trione Monomethanesulphonate

    48. Bromocriptine Mesylate (usp)

    49. Bromocriptine Mesylate- Bio-x

    50. Bromocriptine Mesilate (jp17)

    51. Chembl1200503

    52. Dtxsid6020197

    53. 2-bromo ?-ergocryptine Mesylate

    54. Cb 154 Methanesulfonate (salt)

    55. C32h40brn5o5.ch3so3h

    56. Hms1568i04

    57. Hms3260d03

    58. Hms3411k09

    59. Hms3675k09

    60. Hms3712i04

    61. 2-bromo Alpha-ergocryptine Mesylate

    62. Bromocriptine Mesilate [jan]

    63. Tox21_303597

    64. Tox21_500171

    65. Hy-12705a

    66. Bromocriptine Mesylate [vandf]

    67. .alpha.-ergocryptine, Methanesulfonate

    68. Akos015896276

    69. Bromocriptine Mesilate [mart.]

    70. Bromocriptine Mesilate [who-dd]

    71. Bromocriptine Mesylate [usp-rs]

    72. Ccg-220121

    73. Ccg-221475

    74. Cs-6048

    75. Lp00171

    76. Nsc 755915

    77. Nsc-169774

    78. Ncgc00257268-01

    79. Ncgc00260856-01

    80. Bb164266

    81. Ergotaman-3',6',18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, Monomethanesulfonate (salt), (5'alpha)-

    82. Bromocriptine Methanesulfonate [mi]

    83. Bromocriptine Mesylate [orange Book]

    84. 2-bromo-a-ergocryptine Methanesulfonate Salt

    85. B6298

    86. Bromocriptine Mesilate [ep Monograph]

    87. Eu-0100171

    88. Bromocriptine Mesylate [usp Monograph]

    89. B 2134

    90. D00780

    91. D81822

    92. 2-bromo-.alpha.-ergocryptine Monomethanesulfonate

    93. A903911

    94. Sr-01000075356-1

    95. Sr-01000597796-1

    96. Sr-01000597796-2

    97. Q27105974

    98. 2-bromoergocryptine Monomethanesulphonate (salt)

    99. (+)-2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6'-18-trione Methanesulfonate Salt

    100. (5'alpha)-2-bromo-12'-hydroxy-5'-(2-methylpropyl)-2'-(propan-2-yl)-3',6',18-trioxoergotaman Methanesulfonate

    101. (5'alpha)-2-bromo-12'-hydroxy-5'-isobutyl-2'-isopropyl-3',6',18-trioxoergotaman Methanesulfonate

    102. (6ar,9r)-5-bromo-n-[(1s,2s,4r,7s)-2-hydroxy-7-(2-methylpropyl)-5,8-dioxo-4-propan-2-yl-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9-tetrahydro-4h-indolo[4,3-fg]quinoline-9-carboxamide;methanesulfonic Acid

    103. Ergotaman-3',6',18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, (5.alpha.)-, Methanesulfonate (1:1)

    104. Ergotaman-3',6',18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, Monomethanesulfonate (salt), (5'.alpha.)-

    105. Ergotaman-3',6',18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, Monomethanesulphonate (salt), (5'.alpha.)-

    2.4 Create Date
    2005-03-26
    3 Chemical and Physical Properties
    Molecular Weight 750.7 g/mol
    Molecular Formula C33H44BrN5O8S
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count9
    Rotatable Bond Count5
    Exact Mass749.20940 g/mol
    Monoisotopic Mass749.20940 g/mol
    Topological Polar Surface Area181 Ų
    Heavy Atom Count48
    Formal Charge0
    Complexity1320
    Isotope Atom Count0
    Defined Atom Stereocenter Count6
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 6  
    Drug NameBromocriptine mesylate
    Drug LabelBromocriptine mesylate is an ergot derivative with potent dopamine receptor agonist activity. Each bromocriptine mesylate tablet, USP for oral administration contains 2.5 mg bromocriptine (as the mesylate). Bromocriptine mesylate is chemically design...
    Active IngredientBromocriptine mesylate
    Dosage FormTablet; Capsule
    RouteOral
    Strengtheq 5mg base; eq 2.5mg base
    Market StatusPrescription
    CompanyLek Pharms; Paddock; Zydus Pharms Usa; Mylan

    2 of 6  
    Drug NameCycloset
    PubMed HealthBromocriptine (By mouth)
    Drug ClassesAntidiabetic, Antiparkinsonian, Prolactin Secretion Inhibitor
    Drug LabelCYCLOSET Tablets contain bromocriptine mesylate, a dopamine receptor agonist. Bromocriptine mesylate is chemically designated [Ergotaman-3',6',18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, monomethanesulf
    Active IngredientBromocriptine mesylate
    Dosage FormTablet
    RouteOral
    Strengtheq 0.8mg base
    Market StatusPrescription
    CompanyVeroscience

    3 of 6  
    Drug NameParlodel
    PubMed HealthBromocriptine (By mouth)
    Drug ClassesAntidiabetic, Antiparkinsonian, Prolactin Secretion Inhibitor
    Drug LabelParlodel (bromocriptine mesylate) is an ergot derivative with potent dopamine receptor agonist activity. Each Parlodel (bromocriptine mesylate) SnapTabs tablet for oral administration contains 2 mg and each capsule contains 5 mg bromocriptine...
    Active IngredientBromocriptine mesylate
    Dosage FormTablet; Capsule
    RouteOral
    Strengtheq 5mg base; eq 2.5mg base
    Market StatusPrescription
    CompanyUs Pharms Holdings I

    4 of 6  
    Drug NameBromocriptine mesylate
    Drug LabelBromocriptine mesylate is an ergot derivative with potent dopamine receptor agonist activity. Each bromocriptine mesylate tablet, USP for oral administration contains 2.5 mg bromocriptine (as the mesylate). Bromocriptine mesylate is chemically design...
    Active IngredientBromocriptine mesylate
    Dosage FormTablet; Capsule
    RouteOral
    Strengtheq 5mg base; eq 2.5mg base
    Market StatusPrescription
    CompanyLek Pharms; Paddock; Zydus Pharms Usa; Mylan

    5 of 6  
    Drug NameCycloset
    PubMed HealthBromocriptine (By mouth)
    Drug ClassesAntidiabetic, Antiparkinsonian, Prolactin Secretion Inhibitor
    Drug LabelCYCLOSET Tablets contain bromocriptine mesylate, a dopamine receptor agonist. Bromocriptine mesylate is chemically designated [Ergotaman-3',6',18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, monomethanesulf
    Active IngredientBromocriptine mesylate
    Dosage FormTablet
    RouteOral
    Strengtheq 0.8mg base
    Market StatusPrescription
    CompanyVeroscience

    6 of 6  
    Drug NameParlodel
    PubMed HealthBromocriptine (By mouth)
    Drug ClassesAntidiabetic, Antiparkinsonian, Prolactin Secretion Inhibitor
    Drug LabelParlodel (bromocriptine mesylate) is an ergot derivative with potent dopamine receptor agonist activity. Each Parlodel (bromocriptine mesylate) SnapTabs tablet for oral administration contains 2 mg and each capsule contains 5 mg bromocriptine...
    Active IngredientBromocriptine mesylate
    Dosage FormTablet; Capsule
    RouteOral
    Strengtheq 5mg base; eq 2.5mg base
    Market StatusPrescription
    CompanyUs Pharms Holdings I

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Antiparkinson Agents

    Agents used in the treatment of Parkinson's disease. The most commonly used drugs act on the dopaminergic system in the striatum and basal ganglia or are centrally acting muscarinic antagonists. (See all compounds classified as Antiparkinson Agents.)

    Hormone Antagonists

    Chemical substances which inhibit the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. (See all compounds classified as Hormone Antagonists.)

    Dopamine Agonists

    Drugs that bind to and activate dopamine receptors. (See all compounds classified as Dopamine Agonists.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Ergot Derivative [EPC]; Ergolines [CS]

    API Reference Price

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ESTATE, WAMAN PATIL MARG, GOVANDI,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1681929000,"product":"BROMOCRIPTINE MESYLATE","address":"SURVEY NO.225, SAMPANBOLE VILLAGE, SHAMIRPET MANDAL","city":"MEDCHAL-MALKAKGIRI DISTRICT,TELANGA","supplier":"TEVA API","supplierCountry":"CZECH REPUBLIC","foreign_port":"NA","customer":"ALPHAMED FORMULATIONS PRIVATE ","customerCountry":"INDIA","quantity":"3.60","actualQuantity":"3.6","unit":"KGS","unitRateFc":"8500","totalValueFC":"30934.6","currency":"USD","unitRateINR":"704225","date":"20-Apr-2023","totalValueINR":"2535210","totalValueInUsd":"30934.6","indian_port":"HYDERABAD AIR","hs_no":"29396900","bill_no":"5595097","productDescription":"API","marketType":"REGULATED MARKET","country":"CZECH REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SURVEY NO.225, SAMPANBOLE VILLAGE, SHAMIRPET MANDAL"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1700591400,"product":"BROMOCRIPTINE MESYLATE USP","address":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H","city":"AHMEDABAD,GUJARAT","supplier":"TEVA API","supplierCountry":"CZECH REPUBLIC","foreign_port":"PRAGUE - RUZYNE","customer":"ZYDUS LIFESCIENCES LIMITED","customerCountry":"INDIA","quantity":"1.50","actualQuantity":"1.5","unit":"KGS","unitRateFc":"24000","totalValueFC":"36358.4","currency":"USD","unitRateINR":"2018400","date":"22-Nov-2023","totalValueINR":"3027600","totalValueInUsd":"36358.4","indian_port":"Bombay Air","hs_no":"29396900","bill_no":"8882071","productDescription":"API","marketType":"REGULATED MARKET","country":"CZECH REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"PRAGUE - RUZYNE","supplierAddress":"PIET HEIN BUILDING PIET HEINKADE 107, 1019 GM AMSTERDAM Amsterdam, , Netherlands Netherlands","customerAddress":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1702492200,"product":"BROMOCRIPTINE MESYLATE","address":"B - 124, ANTOP HILL WAREHOUSING","city":"WADALA (E), MUMBAI,MAHARASHTRA","supplier":"TEVA API","supplierCountry":"CZECH REPUBLIC","foreign_port":"PRAGUE - RUZYNE","customer":"AADITYA PHARMACHEM","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"9000","totalValueFC":"18228.5","currency":"USD","unitRateINR":"758700","date":"14-Dec-2023","totalValueINR":"1517400","totalValueInUsd":"18228.5","indian_port":"Bombay Air","hs_no":"29396900","bill_no":"9230694","productDescription":"API","marketType":"REGULATED MARKET","country":"CZECH REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"PRAGUE - RUZYNE","supplierAddress":"PIET HEIN BUILDING, PIET HEINKADE 107 1019 GM AMSTERDAM THE NETHERLANDS , , NETHERLANDS NETHERLANDS","customerAddress":"B - 124, ANTOP HILL WAREHOUSING"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1709145000,"product":"BROMOCRIPTINE MESYLATE ITEM NO. 722210","address":"23-24, KALPTARU COURT, DR.C.G.ROAD,","city":"MUMBAI MAHARASHTRA","supplier":"TEVA PHARMACEUTICAL INDUSTRIES","supplierCountry":"CZECH REPUBLIC","foreign_port":"PRAGUE - RUZYNE","customer":"MANEESH PHARMACEUTICALS LIMITED","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"8500","totalValueFC":"17189.8","currency":"USD","unitRateINR":"713150","date":"29-Feb-2024","totalValueINR":"1426300","totalValueInUsd":"17189.8","indian_port":"Bombay Air","hs_no":"29396900","bill_no":"2358871","productDescription":"API","marketType":"REGULATED MARKET","country":"CZECH REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"PRAGUE - RUZYNE","supplierAddress":"OSTRAVSKA 29, C.P. 305,OPAVAKOMAROV 747 70SDNF CZ","customerAddress":"23-24, KALPTARU COURT, DR.C.G.ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1710959400,"product":"BROMOCRIPTINE MESYLATE MICRONIZE","address":"SECOND FLOOR, BLOCK-III,MY HOME HUB","city":"HYDERABAD, AP","supplier":"TEVA API","supplierCountry":"CZECH REPUBLIC","foreign_port":"PRAGUE - RUZYNE","customer":"GRANULES INDIA LIMITED","customerCountry":"INDIA","quantity":"8.00","actualQuantity":"8","unit":"KGS","unitRateFc":"25000","totalValueFC":"212209.7","currency":"USD","unitRateINR":"2202625","date":"21-Mar-2024","totalValueINR":"17621000","totalValueInUsd":"212209.7","indian_port":"Hyderabad Air","hs_no":"29396900","bill_no":"2676910","productDescription":"API","marketType":"REGULATED MARKET","country":"CZECH REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"PRAGUE - RUZYNE","supplierAddress":"Piet Hein Building, Piet Heinkade 107 1019 GM Amsterdam The Netherlands Netherlands","customerAddress":"SECOND FLOOR, BLOCK-III,MY HOME HUB"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1719772200,"product":"BROMOCRIPTINE MESYLATE ITEM NO. 722210","address":"23-24, KALPTARU COURT, DR.C.G.ROAD,","city":"MUMBAI MAHARASHTRA","supplier":"TEVA PHARMACEUTICAL INDUSTRIES","supplierCountry":"CZECH REPUBLIC","foreign_port":"PRAGUE - RUZYNE","customer":"MANEESH PHARMACEUTICALS LIMITED","customerCountry":"INDIA","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"8500","totalValueFC":"25716.3","currency":"USD","unitRateINR":"716550","date":"01-Jul-2024","totalValueINR":"2149650","totalValueInUsd":"25716.3","indian_port":"Bombay Air","hs_no":"29396900","bill_no":"4277226","productDescription":"API","marketType":"REGULATED MARKET","country":"CZECH REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"PRAGUE - RUZYNE","supplierAddress":"OSTRAVSKA 29, C.P. 305,OPAVAKOMAROV 747 70SDNF CZ","customerAddress":"23-24, KALPTARU COURT, DR.C.G.ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725388200,"product":"BROMOCRIPTINE MESYLATE USP","address":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H","city":"AHMEDABAD,GUJARAT","supplier":"TEVA API","supplierCountry":"CZECH REPUBLIC","foreign_port":"PRAGUE - RUZYNE","customer":"ZYDUS LIFESCIENCES LIMITED","customerCountry":"INDIA","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"24000","totalValueFC":"72901.1","currency":"USD","unitRateINR":"2036400","date":"04-Sep-2024","totalValueINR":"6109200","totalValueInUsd":"72901.1","indian_port":"Bombay Air","hs_no":"29396900","bill_no":"5415477","productDescription":"API","marketType":"REGULATED MARKET","country":"CZECH REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"PRAGUE - 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SDNF Netherlands","customerAddress":"3RD FLOOR, PLOT NO.2, MAITRIVIHAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1730313000,"product":"BROMOCRIPTINE MESYLATE (FORM 10 LIC NO.IL\/BD-015260 BD-113)","address":"INGA HOUSE","city":"BOMBAY ,MAHARASHTRA","supplier":"TEVA API","supplierCountry":"CZECH REPUBLIC","foreign_port":"PRAGUE - RUZYNE","customer":"INGA LABORATORIES PRIVATE ","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"10750","totalValueFC":"21736.3","currency":"USD","unitRateINR":"913212.5","date":"31-Oct-2024","totalValueINR":"1826425","totalValueInUsd":"21736.3","indian_port":"Bombay Air","hs_no":"29398000","bill_no":"6438192","productDescription":"API","marketType":"REGULATED MARKET","country":"CZECH REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"PRAGUE - RUZYNE","supplierAddress":"PIET HEIN BUILDING, PIET HEINKADE 1 07 1019 GM Amsterdam, , NETHERLANDS SDNF NETHERLANDS","customerAddress":"INGA HOUSE"}]
    05-Jan-2021
    31-Oct-2024
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    ABOUT THIS PAGE

    Bromocriptine Mesylate Manufacturers

    A Bromocriptine Mesylate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Bromocriptine Mesylate, including repackagers and relabelers. The FDA regulates Bromocriptine Mesylate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Bromocriptine Mesylate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Bromocriptine Mesylate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Bromocriptine Mesylate Suppliers

    A Bromocriptine Mesylate supplier is an individual or a company that provides Bromocriptine Mesylate active pharmaceutical ingredient (API) or Bromocriptine Mesylate finished formulations upon request. The Bromocriptine Mesylate suppliers may include Bromocriptine Mesylate API manufacturers, exporters, distributors and traders.

    click here to find a list of Bromocriptine Mesylate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Bromocriptine Mesylate USDMF

    A Bromocriptine Mesylate DMF (Drug Master File) is a document detailing the whole manufacturing process of Bromocriptine Mesylate active pharmaceutical ingredient (API) in detail. Different forms of Bromocriptine Mesylate DMFs exist exist since differing nations have different regulations, such as Bromocriptine Mesylate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Bromocriptine Mesylate DMF submitted to regulatory agencies in the US is known as a USDMF. Bromocriptine Mesylate USDMF includes data on Bromocriptine Mesylate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Bromocriptine Mesylate USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Bromocriptine Mesylate suppliers with USDMF on PharmaCompass.

    Bromocriptine Mesylate JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Bromocriptine Mesylate Drug Master File in Japan (Bromocriptine Mesylate JDMF) empowers Bromocriptine Mesylate API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Bromocriptine Mesylate JDMF during the approval evaluation for pharmaceutical products. At the time of Bromocriptine Mesylate JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Bromocriptine Mesylate suppliers with JDMF on PharmaCompass.

    Bromocriptine Mesylate CEP

    A Bromocriptine Mesylate CEP of the European Pharmacopoeia monograph is often referred to as a Bromocriptine Mesylate Certificate of Suitability (COS). The purpose of a Bromocriptine Mesylate CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Bromocriptine Mesylate EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Bromocriptine Mesylate to their clients by showing that a Bromocriptine Mesylate CEP has been issued for it. The manufacturer submits a Bromocriptine Mesylate CEP (COS) as part of the market authorization procedure, and it takes on the role of a Bromocriptine Mesylate CEP holder for the record. Additionally, the data presented in the Bromocriptine Mesylate CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Bromocriptine Mesylate DMF.

    A Bromocriptine Mesylate CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Bromocriptine Mesylate CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Bromocriptine Mesylate suppliers with CEP (COS) on PharmaCompass.

    Bromocriptine Mesylate NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Bromocriptine Mesylate as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Bromocriptine Mesylate API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Bromocriptine Mesylate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Bromocriptine Mesylate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Bromocriptine Mesylate NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Bromocriptine Mesylate suppliers with NDC on PharmaCompass.

    Bromocriptine Mesylate GMP

    Bromocriptine Mesylate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Bromocriptine Mesylate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Bromocriptine Mesylate GMP manufacturer or Bromocriptine Mesylate GMP API supplier for your needs.

    Bromocriptine Mesylate CoA

    A Bromocriptine Mesylate CoA (Certificate of Analysis) is a formal document that attests to Bromocriptine Mesylate's compliance with Bromocriptine Mesylate specifications and serves as a tool for batch-level quality control.

    Bromocriptine Mesylate CoA mostly includes findings from lab analyses of a specific batch. For each Bromocriptine Mesylate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Bromocriptine Mesylate may be tested according to a variety of international standards, such as European Pharmacopoeia (Bromocriptine Mesylate EP), Bromocriptine Mesylate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Bromocriptine Mesylate USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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