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1. Ambodryl
2. Bromodiphenhydramine
3. Bromodiphenhydramine Hydrochloride
1. Bromodiphenhydramine
2. Bromdiphenhydramine
3. 118-23-0
4. Histabromamine
5. Deserol
6. Neo-benadryl
7. Bromazina
8. Bromazinum
9. Amodryl
10. Ambodryl
11. Bromazin
12. 2-[(4-bromophenyl)-phenylmethoxy]-n,n-dimethylethanamine
13. 2-(p-bromo-alpha-phenylbenzyloxy)-n,n-dimethylethylamine
14. Beta-(p-bromobenzhydryloxy)ethyldimethylamine
15. 2-((4-bromophenyl)(phenyl)methoxy)-n,n-dimethylethanamine
16. N-2-(4-bromobenzhydryloxy)ethyldimethylamine
17. Beta-dimethylaminoethyl P-bromobenzhydryl Ether
18. Chebi:59177
19. Bromdiphenhydraminum
20. T032bi7727
21. 2-[(4-bromophenyl)(phenyl)methoxy]-n,n-dimethylethanamine
22. Ethanamine, 2-[(4-bromophenyl)phenylmethoxy]-n,n-dimethyl-
23. Bromo-benadryl
24. Bromazine [inn:ban]
25. 2-(4-bromobenzhydryloxy)-nn-dimethylethylamine
26. Bromazinum [inn-latin]
27. Bromazina [inn-spanish]
28. Ethanamine, 2-((4-bromophenyl)phenylmethoxy)-n,n-dimethyl-
29. (6r,7r)-7-[[(z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid,dihydrate
30. Einecs 204-238-8
31. Bromazin Base
32. Deserol Base
33. Unii-t032bi7727
34. Bromo-benadryl Base
35. Bromodiphen-hydramine
36. 4-bromodiphen Hydramine
37. Bromazine [inn]
38. Diphenhydramine Impurity C
39. Dsstox_cid_2688
40. Bromazine [who-dd]
41. Dsstox_rid_97539
42. Dsstox_gsid_22688
43. Schembl29806
44. Gtpl7132
45. Dimenhydrinate Impurity H
46. Chembl1201245
47. Dtxsid6022688
48. Bdbm81465
49. Bromodiphenhydramine [mi]
50. (+/-)-bromodiphenhydramine
51. 2-{[(4-bromophenyl)(phenyl)methyl]oxy}-n,n-dimethylethanamine
52. Bromodiphenhydramine [vandf]
53. Cas_2444
54. Hy-b1568
55. Nsc_2444
56. Tox21_113667
57. Pdsp1_000145
58. Pdsp2_000144
59. Bromodiphenhydramine, (+/-)-
60. Db01237
61. Ncgc00249891-01
62. Cas-118-23-0
63. Cs-0013459
64. .beta.-(p-bromobenzhydryloxy)ethyldimethylamine
65. 4-bromodiphen Hydramine [usp Impurity]
66. Dimenhydrinate Impurity H [ep Impurity]
67. L001164
68. Sr-01000944388
69. Q4926102
70. Sr-01000944388-1
71. {2-[(4-bromophenyl)(phenyl)methoxy]ethyl}dimethylamine
72. 2-[(4-bromophenyl)(phenyl)methoxy]-n,n-dimethylethanamine #
73. 2-[(p-bromo-.alpha.-phenylbenzyl)oxy]-n,n-dimethylethylamine
74. Diphenhydramine Hydrochloride Impurity C [ep Impurity]
75. Ethylamine, 2-[(p-bromo-.alpha.-phenylbenzyl)oxy]-n,n-dimethyl-
| Molecular Weight | 334.2 g/mol |
|---|---|
| Molecular Formula | C17H20BrNO |
| XLogP3 | 4 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 6 |
| Exact Mass | 333.07283 g/mol |
| Monoisotopic Mass | 333.07283 g/mol |
| Topological Polar Surface Area | 12.5 Ų |
| Heavy Atom Count | 20 |
| Formal Charge | 0 |
| Complexity | 258 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
For management of symptoms related to hay fever and other types of allergy and used to help bring up phlegm, thin secretions, and make a cough productive.
Bromodiphenhydramine is an antihistamine of the ethanolamine class. Ethanolamine antihistamines have significant antimuscarinic activity and produce marked sedation in most patients. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease. Rather than preventing the release of histamine, as do cromolyn and nedocromil, Bromodiphenhydramine competes with free histamine for binding at HA-receptor sites. Bromodiphenhydramine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Ethanolamine derivatives have greater anticholinergic activity than do other antihistamines, which probably accounts for the antidyskinetic action of Bromodiphenhydramine. This anticholinergic action appears to be due to a central antimuscarinic effect, which also may be responsible for its antiemetic effects, although the exact mechanism is unknown.
R - Respiratory system
R06 - Antihistamines for systemic use
R06A - Antihistamines for systemic use
R06AA - Aminoalkyl ethers
R06AA01 - Bromazine
Absorption
Well absorbed in the digestive tract.
Hepatic (cytochrome P-450 system); some renal.
1 to 4 hours
Bromodiphenhydramine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding.
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ABOUT THIS PAGE
A Bromodiphenhydramine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Bromodiphenhydramine, including repackagers and relabelers. The FDA regulates Bromodiphenhydramine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Bromodiphenhydramine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Bromodiphenhydramine supplier is an individual or a company that provides Bromodiphenhydramine active pharmaceutical ingredient (API) or Bromodiphenhydramine finished formulations upon request. The Bromodiphenhydramine suppliers may include Bromodiphenhydramine API manufacturers, exporters, distributors and traders.
click here to find a list of Bromodiphenhydramine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Bromodiphenhydramine DMF (Drug Master File) is a document detailing the whole manufacturing process of Bromodiphenhydramine active pharmaceutical ingredient (API) in detail. Different forms of Bromodiphenhydramine DMFs exist exist since differing nations have different regulations, such as Bromodiphenhydramine USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Bromodiphenhydramine DMF submitted to regulatory agencies in the US is known as a USDMF. Bromodiphenhydramine USDMF includes data on Bromodiphenhydramine's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Bromodiphenhydramine USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Bromodiphenhydramine suppliers with USDMF on PharmaCompass.
Bromodiphenhydramine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Bromodiphenhydramine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Bromodiphenhydramine GMP manufacturer or Bromodiphenhydramine GMP API supplier for your needs.
A Bromodiphenhydramine CoA (Certificate of Analysis) is a formal document that attests to Bromodiphenhydramine's compliance with Bromodiphenhydramine specifications and serves as a tool for batch-level quality control.
Bromodiphenhydramine CoA mostly includes findings from lab analyses of a specific batch. For each Bromodiphenhydramine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Bromodiphenhydramine may be tested according to a variety of international standards, such as European Pharmacopoeia (Bromodiphenhydramine EP), Bromodiphenhydramine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Bromodiphenhydramine USP).
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