Find Bufylline manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Bufylline, 5634-34-4, Butaphyllamine, Ambuphylline [usan], Theophylline-2-aminoisobutanol, Vou5v0b772
Molecular Formula
C11H19N5O3
Molecular Weight
269.30  g/mol
InChI Key
SEIRRUDMPNNSCY-UHFFFAOYSA-N
FDA UNII
VOU5V0B772

Bufylline
1 2D Structure

Bufylline

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-amino-2-methylpropan-1-ol;1,3-dimethyl-7H-purine-2,6-dione
2.1.2 InChI
InChI=1S/C7H8N4O2.C4H11NO/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;1-4(2,5)3-6/h3H,1-2H3,(H,8,9);6H,3,5H2,1-2H3
2.1.3 InChI Key
SEIRRUDMPNNSCY-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(C)(CO)N.CN1C2=C(C(=O)N(C1=O)C)NC=N2
2.2 Other Identifiers
2.2.1 UNII
VOU5V0B772
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Bufylline

2. Theophylline Aminoisobutanol

2.3.2 Depositor-Supplied Synonyms

1. Bufylline

2. 5634-34-4

3. Butaphyllamine

4. Ambuphylline [usan]

5. Theophylline-2-aminoisobutanol

6. Vou5v0b772

7. Theophylline Compound With 2-amino-2-methyl-1-propanol (1:1)

8. 1h-purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, Compd. With 2-amino-2-methyl-1-propanol (1:1)

9. Ambuphylline (usan)

10. Buthoid

11. 2-amino-2-methylpropan-1-ol;1,3-dimethyl-7h-purine-2,6-dione

12. Theophylline Aminoisobutanol

13. Einecs 227-077-5

14. Unii-vou5v0b772

15. 1-propanol, 2-amino-2-methyl-, Compd. With Theophylline (1:1)

16. Bufylline (ban)

17. Butaphyllamine (tn)

18. Theophylline, Compd. With 2-amino-2-methyl-1-propanol (1:1)

19. Ambuphylline [mi]

20. Bufylline [mart.]

21. 3,7-dihydro-1,3-dimethyl-1h-purine-2,6-dione, Compound With 2-amino-2-methylpropan-1-ol (1:1)

22. Ambuphylline [who-dd]

23. Schembl355316

24. Chembl2104089

25. Dtxsid60204880

26. Akos016340427

27. Db13812

28. Ks-1324

29. Hy-105647

30. Cs-0026398

31. D02884

32. 634t344

33. Q4741993

34. 1,3-dimethyl-1h-purine-2,6(3h,7h)-dione Compound With 2-amino-2-methylpropan-1-ol (1:1)

35. 1,3-dimethyl-2,3,6,7-tetrahydro-1h-purine-2,6-dione; 2-amino-2-methylpropan-1-ol

2.4 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 269.30 g/mol
Molecular Formula C11H19N5O3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Exact Mass269.14878949 g/mol
Monoisotopic Mass269.14878949 g/mol
Topological Polar Surface Area116 Ų
Heavy Atom Count19
Formal Charge0
Complexity310
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Vasodilator Agents

Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)


Bronchodilator Agents

Agents that cause an increase in the expansion of a bronchus or bronchial tubes. (See all compounds classified as Bronchodilator Agents.)


4.2 ATC Code

R - Respiratory system

R03 - Drugs for obstructive airway diseases

R03D - Other systemic drugs for obstructive airway diseases

R03DA - Xanthines

R03DA10 - Bufylline


ABOUT THIS PAGE

Bufylline Manufacturers

A Bufylline manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Bufylline, including repackagers and relabelers. The FDA regulates Bufylline manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Bufylline API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Bufylline Suppliers

A Bufylline supplier is an individual or a company that provides Bufylline active pharmaceutical ingredient (API) or Bufylline finished formulations upon request. The Bufylline suppliers may include Bufylline API manufacturers, exporters, distributors and traders.

Bufylline GMP

Bufylline Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Bufylline GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Bufylline GMP manufacturer or Bufylline GMP API supplier for your needs.

Bufylline CoA

A Bufylline CoA (Certificate of Analysis) is a formal document that attests to Bufylline's compliance with Bufylline specifications and serves as a tool for batch-level quality control.

Bufylline CoA mostly includes findings from lab analyses of a specific batch. For each Bufylline CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Bufylline may be tested according to a variety of international standards, such as European Pharmacopoeia (Bufylline EP), Bufylline JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Bufylline USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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