DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Contact Supplier

Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

3 API Suppliers, 3 USDMF, $ API Reference Price

3 API Suppliers
3 USDMF
$ API Reference Price

DIGITAL CONTENT

3 NEWS #PharmaBuzz

media
3 NEWS #PharmaBuzz

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 105,340

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 33017-11-7, Proinsulin c-peptide (human), Human c-peptide, Insulin c-peptide, Nmij-crm 6901a, Proinsulin c-peptide human

Molecular Formula

C₁₂₉H₂₁₁N₃₅O₄₈

Molecular Weight

3020.3 g/mol

InChI Key

VOUAQYXWVJDEQY-QENPJCQMSA-N

FDA UNII

O2J76Y002M

The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.

1 2D Structure

C-Peptide

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(4S)-4-amino-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[2-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[2-[[2-[(2S)-2-[[2-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(1S)-4-amino-1-carboxy-4-oxobutyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1,5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]amino]-2-oxoethyl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid

2.1.2 InChI

InChI=1S/C129H211N35O48/c1-58(2)42-77(155-113(195)74(31-39-102(184)185)151-127(209)105(65(15)16)162-114(196)71(25-32-88(131)167)145-95(174)54-141-126(208)104(64(13)14)161-115(197)72(26-33-89(132)168)150-118(200)80(45-61(7)8)156-121(203)83(48-103(186)187)159-112(194)73(30-38-101(182)183)148-107(189)67(18)143-109(191)69(130)24-36-99(178)179)111(193)138-50-93(172)135-49-92(171)136-55-98(177)163-40-20-22-86(163)124(206)140-51-94(173)142-66(17)106(188)137-52-96(175)146-84(56-165)122(204)157-81(46-62(9)10)119(201)152-75(27-34-90(133)169)128(210)164-41-21-23-87(164)125(207)160-78(43-59(3)4)116(198)144-68(19)108(190)154-79(44-60(5)6)117(199)149-70(29-37-100(180)181)110(192)139-53-97(176)147-85(57-166)123(205)158-82(47-63(11)12)120(202)153-76(129(211)212)28-35-91(134)170/h58-87,104-105,165-166H,20-57,130H2,1-19H3,(H2,131,167)(H2,132,168)(H2,133,169)(H2,134,170)(H,135,172)(H,136,171)(H,137,188)(H,138,193)(H,139,192)(H,140,206)(H,141,208)(H,142,173)(H,143,191)(H,144,198)(H,145,174)(H,146,175)(H,147,176)(H,148,189)(H,149,199)(H,150,200)(H,151,209)(H,152,201)(H,153,202)(H,154,190)(H,155,195)(H,156,203)(H,157,204)(H,158,205)(H,159,194)(H,160,207)(H,161,197)(H,162,196)(H,178,179)(H,180,181)(H,182,183)(H,184,185)(H,186,187)(H,211,212)/t66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,104-,105-/m0/s1

2.1.3 InChI Key

VOUAQYXWVJDEQY-QENPJCQMSA-N

2.1.4 Canonical SMILES

CC(C)CC(C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NCC(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)O)NC(=O)C1CCCN1C(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)CNC(=O)C(C)NC(=O)CNC(=O)C2CCCN2C(=O)CNC(=O)CNC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C(CCC(=O)N)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CCC(=O)O)N

2.1.5 Isomeric SMILES

C[C@@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)O)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)CNC(=O)CNC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(=O)N)NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)N

2.2 Other Identifiers

2.2.1 UNII

O2J76Y002M

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Cbx129801

2. C Peptide

3. C Peptide, Proinsulin

4. C-peptide

5. C-peptide, Proinsulin

6. Connecting Peptide

7. Proinsulin C Peptide

8. Proinsulin C-peptide

2.3.2 Depositor-Supplied Synonyms

1. 33017-11-7

2. Proinsulin C-peptide (human)

3. Human C-peptide

4. Insulin C-peptide

5. Nmij-crm 6901a

6. Proinsulin C-peptide Human

7. C-peptide (human) Acetate Salt

8. C-peptide, Proinsulin

9. C-peptide(human)

10. C-peptide, Human

11. Cbx129801

12. Cbx 129801

13. Gtpl6145

14. Chembl4594409

15. Dtxsid00186651

16. Mfcd00076295

17. C-peptide Fragment 3-33 Human, >=85% (hplc)

18. Glu-ala-glu-asp-leu-gln-val-gly-gln-val-glu-leu-gly-gly-gly-pro-gly-ala-gly-ser-leu-gln-pro-leu-ala-leu-glu-gly-ser-leu-gln

19. H-glu-ala-glu-asp-leu-gln-val-gly-gln-val-glu-leu-gly-gly-gly-pro-gly-ala-gly-ser-leu-gln-pro-leu-ala-leu-glu-gly-ser-leu-gln-oh

20. H-glu-val-glu-asp-leu-gln-val-arg-asp-val-glu-leu-ala-gly-ala-pro-gly-glu-gly-gly-leu-gln-pro-leu-ala-leu-glu-gly-ala-leu-gln-oh

21. Proinsulin Connecting Peptide (human), 1-de-l-arginine-2-de-l-arginine-34-de-l-lysine-35-de-l-arginine-

2.4 Create Date

2007-07-04

3 Chemical and Physical Properties

Molecular Formula	C₁₂₉H₂₁₁N₃₅O₄₈
Molecular Weight	3020.3 g/mol
XLogP3	-12.6
Hydrogen Bond Donor Count	41
Hydrogen Bond Acceptor Count	49
Rotatable Bond Count	101
Exact Mass	3019.5179284 g/mol
Monoisotopic Mass	3018.5145736 g/mol
Topological Polar Surface Area	1320 Å²
Heavy Atom Count	212
Formal Charge	0
Complexity	7190
Isotope Atom Count	0
Defined Atom Stereocenter Count	24
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

API SUPPLIERS

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

USDMF

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

API Reference Price

[{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q2","strtotime":1622399400,"product":"ECHINOCANDIN B CYCLIC-PEPTIDE NUCLEUS HYDROCHLORIDE SALT (ECBN,HCL)(2R,6S,9S,11R,12R,14AS,15S,16S,20S,23S,25AS)-9-AMINO-","address":"SUBHASH ROAD-A,VILE PARLE (EAST),","city":"MUMBAI, MAHA","supplier":"REGEN BIOPHARMA","supplierCountry":"CHINA","foreign_port":"","customer":"GUFIC BIOSCIENCES","customerCountry":"INDIA","quantity":"3.53","actualQuantity":"3525","unit":"GMS","unitRateFc":"116.2","totalValueFC":"414183.5","currency":"USD","unitRateINR":"8606.7","date":"31-May-2021","totalValueINR":"30338670.38","totalValueInUsd":"414183.5","indian_port":"MADRAS AIR","hs_no":"29349990","bill_no":"4142040","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"","supplierAddress":"","customerAddress":"SUBHASH ROAD-A,VILE PARLE (EAST),"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1689877800,"product":"ECHINOCANDIN B CYCLIC-PEPTIDE NUCLEUS HYDROCHLORIDE SALT (ECBN,HCL)(2R,6S,9S,11R,12R,14AS,15S,16S,20S,23S,25AS)-9-AMINO-","address":"SHOP-37, FIRST FLR. KAMLA BHAVAN I I,S. NITYANAND ROAD ANDHERI EAST","city":"MUMBAI,MAHARASHTRA","supplier":"BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO.,LTD","supplierCountry":"CHINA","foreign_port":"NA","customer":"GUFIC BIOSCIENCES","customerCountry":"INDIA","quantity":"1.20","actualQuantity":"1200","unit":"GMS","unitRateFc":"87.5","totalValueFC":"105971.5","currency":"USD","unitRateINR":"7257.9","date":"21-Jul-2023","totalValueINR":"8709749.706","totalValueInUsd":"105971.5","indian_port":"MADRAS AIR","hs_no":"29349990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SHOP-37, FIRST FLR. KAMLA BHAVAN I I,S. NITYANAND ROAD ANDHERI EAST"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1706898600,"product":"ECHINOCANDIN B CYCLIC-PEPTIDE NUCLEUS HYDROCHLORIDE SALT (ECBN,HCL)(2R,6S,9S,11R,12R,14AS,15S,16S,20S,23S,25AS)-9-AMINO-","address":"2NF FLOOR,BUILDING A,","city":"ANDHERI[W],MUMBAI,","supplier":"BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO.,LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"GUFIC BIOSCIENCES","customerCountry":"INDIA","quantity":"2.40","actualQuantity":"2400","unit":"GMS","unitRateFc":"85.5","totalValueFC":"207614.3","currency":"USD","unitRateINR":"7177.7","date":"03-Feb-2024","totalValueINR":"17226540","totalValueInUsd":"207614.3","indian_port":"Madras Air","hs_no":"29349990","bill_no":"9964946","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"ADD:BUILDING C25-C28 NO 218 XINGHUROAD SIP SUZHOU JIANGSU CHINASDNF CHINA","customerAddress":"2NF FLOOR,BUILDING A,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1713724200,"product":"ECHINOCANDIN B CYCLIC-PEPTIDE NUCLEUS HYDROCHLORIDE SALT (ECBN,HCL)(2R,6S,9S,11R,12R,14AS,15S,16S,20S,23S,25AS)-9-AMINO-","address":"2NF FLOOR,BUILDING A,","city":"ANDHERI[W],MUMBAI,","supplier":"BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO.,LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"GUFIC BIOSCIENCES","customerCountry":"INDIA","quantity":"1.81","actualQuantity":"1812","unit":"GMS","unitRateFc":"85.5","totalValueFC":"156582.2","currency":"USD","unitRateINR":"7216.2","date":"22-Apr-2024","totalValueINR":"13075754.4","totalValueInUsd":"156582.2","indian_port":"Madras Air","hs_no":"29349990","bill_no":"3145501","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"ADD:BUILDING C25-C28 NO 218 XINGHUROAD SIP SUZHOU JIANGSU CHINASDNF CHINA","customerAddress":"2NF FLOOR,BUILDING A,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718821800,"product":"ECHINOCANDIN B CYCLIC-PEPTIDE NUCLEUS HYDROCHLORIDE SALT (ECBN,HCL)(2R,6S,9S,11R,12R,14AS,15S,16S,20S,23S,25AS)-9-AMINO-","address":"2NF FLOOR,BUILDING A,","city":"ANDHERI[W],MUMBAI,","supplier":"BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO.,LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"GUFIC BIOSCIENCES","customerCountry":"INDIA","quantity":"1.20","actualQuantity":"1200","unit":"GMS","unitRateFc":"85.5","totalValueFC":"103608.5","currency":"USD","unitRateINR":"7207.7","date":"20-Jun-2024","totalValueINR":"8649180","totalValueInUsd":"103608.5","indian_port":"Madras Air","hs_no":"29349990","bill_no":"4095125","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"ADD:BUILDING C25-C28 NO 218 XINGHUROAD SIP SUZHOU JIANGSU CHINASDNF CHINA","customerAddress":"2NF FLOOR,BUILDING A,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1730226600,"product":"ECHINOCANDIN B CYCLIC-PEPTIDE NUCLEUS HYDROCHLORIDE SALT (ECBN,HCL)(2R,6S,9S,11R,12R,14AS,15S,16S,20S,23S,25AS)-9-AMINO-","address":"2NF FLOOR,BUILDING A,","city":"ANDHERI[W],MUMBAI,","supplier":"BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO.,LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"GUFIC BIOSCIENCES","customerCountry":"INDIA","quantity":"0.60","actualQuantity":"600","unit":"GMS","unitRateFc":"75.5","totalValueFC":"45797.8","currency":"USD","unitRateINR":"6413.7","date":"30-Oct-2024","totalValueINR":"3848235","totalValueInUsd":"45797.8","indian_port":"Madras Air","hs_no":"29349990","bill_no":"6415498","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"ADD:BUILDING C25-C28 NO 218 XINGHU ROAD SIP SUZHOU JIANGSU CHINA SDNF CHINA","customerAddress":"2NF FLOOR,BUILDING A,"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

Upgrade, download data, analyse, strategize, subscribe with us contact

Digital Content

Create Content with PharmaCompass, ask us

NEWS #PharmaBuzz

ABOUT THIS PAGE

Find C-Peptide manufacturers, exporters & distributors on PharmaCompass

C Peptide

ACCESS ALL DATA

Browse all information

CHEMISTRY

Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

3 API Suppliers

3 USDMF

$ API Reference Price

DIGITAL CONTENT

3 NEWS #PharmaBuzz

ACTIVE PHARMA INGREDIENTS

API REF. PRICE (USD/KG)

$ 105,340

MARKET PLACE

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

PATENTS & EXCLUSIVITIES

DIGITAL CONTENT

GLOBAL SALES INFORMATION

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

What are you looking for?