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31 API Suppliers, 11 USDMF, 2 EU WC, 2 KDMF, 10 NDC API, 25 Listed Suppliers, $ API Reference Price

31 API Suppliers
11 USDMF
2 EU WC
2 KDMF
10 NDC API
25 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

69 Drugs in Development

69 Drugs in Development

INTERMEDIATES

16 Intermediates Suppliers

16 Intermediates Suppliers

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44 FDF Dossiers, 8 FDA Orange Book, 11 Europe, 3 Canada, 12 Australia, 3 South Africa, 7 Listed Dossiers

44 FDF Dossiers
8 FDA Orange Book
11 Europe
3 Canada
12 Australia
3 South Africa
7 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

CAPSULE;ORAL - EQ 20MG BASE, CAPSULE;ORAL - EQ 80MG BASE

drugProductComposition
CAPSULE;ORAL - EQ 20MG BASE
CAPSULE;ORAL - EQ 80MG BASE

RELATED EXCIPIENT COMPANIES

1 SPI Pharma, 8 DKSH, 1 Jai Radhe Sales, 8 Gangwal Healthcare, 1 Nanjing Well Pharmaceutical, 4 ACG Worldwide, 7 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 4 BASF, 10 Corel Pharma Chem, 5 DFE Pharma, 1 Finar, 6 Gangwal Chemicals, 5 Ideal Cures Pvt Ltd, 2 Ingredion Pharma Solutions, 21 Kerry, 3 Kima Chemical, 6 Lonza Capsugel, 11 Microlex e.U, 1 Novo Excipients, 2 Pharmatrans-Sanaq, 2 Pluviaendo, 4 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 2 Qualicaps, 14 Roquette, 7 Seppic, 4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 10 Sigachi Industries, 2 The Dow Chemical Company, 1 Valens Pharmachem, 4 Vasa Pharmachem

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46 Coating Systems & Additives, 36 Fillers, Diluents & Binders, 24 Disintegrants & Superdisintegrants, 20 Controlled & Modified Release, 19 Direct Compression, 19 Thickeners and Stabilizers, 15 Lubricants & Glidants, 12 Film Formers & Plasticizers, 12 Granulation, 9 Co-Processed Excipients, 9 Empty Capsules, 5 Coloring Agents, 5 Emulsifying Agents, 4 Vegetarian Capsules, 4 API Stability Enhancers, 4 Taste Masking, 4 Topical, 3 Solubilizers, 3 Rheology Modifiers, 3 Chewable & Orodispersible Aids, 1 Parenteral

DIGITAL CONTENT

3 DATA COMPILATION #PharmaFlow, 2 STOCK RECAP #PipelineProspector, 160 NEWS #PharmaBuzz

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3 DATA COMPILATION #PharmaFlow
2 STOCK RECAP #PipelineProspector
160 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

2 US Medicaid Prescriptions, 9 Finished Drug Prices, 10 Annual Reports

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2 US Medicaid Prescriptions
9 Finished Drug Prices
10 Annual Reports

MARKET PLACE

7 APIs, 2 FDF Dossiers

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7 APIs
2 FDF Dossiers

PATENTS & EXCLUSIVITIES

59 US Patents, 12 US Exclusivities

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59 US Patents
12 US Exclusivities

REF. STANDARDS & IMPURITIES

10 Others

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10 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

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CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 20,542

MARKET PLACE

API

FDF

16INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

69DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

160

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

923,240,109

Annual Reports (USD Million)

2,414

Finished Drug Prices

158 RELATED EXCIPIENT COMPANIES

257EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 1140909-48-3, Cabozantinib malate, Cabozantinib (s)-malate, Cabometyx, Cabozantinib malate (xl184), Xl184

Molecular Formula

C₃₂H₃₀FN₃O₁₀

Molecular Weight

635.6 g/mol

InChI Key

HFCFMRYTXDINDK-WNQIDUERSA-N

FDA UNII

DR7ST46X58

Cabozantinib S-malate is the s-malate salt form of cabozantinib, an orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Cabozantinib strongly binds to and inhibits several RTKs, which are often overexpressed in a variety of cancer cell types, including hepatocyte growth factor receptor (MET), RET (rearranged during transfection), vascular endothelial growth factor receptor types 1 (VEGFR-1), 2 (VEGFR-2), and 3 (VEGFR-3), mast/stem cell growth factor (KIT), FMS-like tyrosine kinase 3 (FLT-3), TIE-2 (TEK tyrosine kinase, endothelial), tropomyosin-related kinase B (TRKB) and AXL. This may result in an inhibition of both tumor growth and angiogenesis, and eventually lead to tumor regression.

1 2D Structure

Cabozantinib

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;(2S)-2-hydroxybutanedioic acid

2.1.2 InChI

InChI=1S/C28H24FN3O5.C4H6O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18;5-2(4(8)9)1-3(6)7/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34);2,5H,1H2,(H,6,7)(H,8,9)/t;2-/m.0/s1

2.1.3 InChI Key

HFCFMRYTXDINDK-WNQIDUERSA-N

2.1.4 Canonical SMILES

COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F.C(C(C(=O)O)O)C(=O)O

2.1.5 Isomeric SMILES

COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F.C([C@@H](C(=O)O)O)C(=O)O

2.2 Other Identifiers

2.2.1 UNII

DR7ST46X58

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Bms 907351

2. Bms-907351

3. Bms907351

4. Cabozantinib

5. Cometriq

6. Xl 184

7. Xl-184

8. Xl184 Cpd

2.3.2 Depositor-Supplied Synonyms

1. 1140909-48-3

2. Cabozantinib Malate

3. Cabozantinib (s)-malate

4. Cabometyx

5. Cabozantinib Malate (xl184)

6. Xl184

7. Cabozantinib (s-malate)

8. Cometriq

9. Cabozantinib S-malate [usan]

10. Dr7st46x58

11. Bms907351

12. Chebi:72319

13. N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-n-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (s)-2-hydroxysuccinate

14. Cabometyx (tn)

15. Cometriq (tn)

16. Cabozantinib Malate (jan)

17. 1-n-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;(2s)-2-hydroxybutanedioic Acid

18. Cabozantinib S-malate (usan)

19. Cabozantinib Malate [jan]

20. Unii-dr7st46x58

21. Butanedioic Acid, 2-hydroxy-, (2s)-, Compd. With N-(4-((6,7-dimethoxy-4-quinolinyl)oxy)phenyl)-n'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1)

22. Butanedioic Acid, 2-hydroxy-, (2s)-, Compd. With N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1)

23. Xl184 Malate

24. Cabozantinib L-malate

25. Bms907351 Malate

26. Xl184(cabozantinib Malate)

27. Mls006010951

28. Chembl2103868

29. Dtxsid60915949

30. Ex-a2819

31. Mfcd20923480

32. S4001

33. 1140909-48-3 (malate)

34. Akos025401945

35. Cabozantinib S-malate [who-dd]

36. Ccg-270301

37. Cs-0201

38. (2s)-2-hydroxybutanedioic Acid Compd. With N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n'-(4-fluor

39. (2s)-2-hydroxybutanedioic Acid Compd. With N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1)

40. Ac-27471

41. As-75255

42. Hy-12044

43. Smr004702755

44. Cabozantinib S-malate [orange Book]

45. Sw218093-2

46. D10095

47. Q27139901

48. (2s)-2-hydroxybutanedioic Acid Compd. With N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide

49. (2s)-2-hydroxybutanedioic Acid Compd. With N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1)

50. (2s)-2-hydroxybutanedioic Acid; N'1-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-n1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

51. 1,1-cyclopropanedicarboxamide, N'-(4-((6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n-(4- Fluorophenyl)- Mono((2s)-2-hydroxybutanedioate)

52. Cyclopropane-1,1-dicarboxylic Acid [4-(6,7-dimethoxy-quinoline-4-yloxy)-phenyl]-amide(4-fluoro-phenyl)-amide, (s) Malate Salt

53. N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide Mono((2s)-2-hydroxybutanedioate)

54. N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-n-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (s)-2-hydroxysuccinate

55. N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (2s)-2-hydroxybutanedioate

2.4 Create Date

2008-12-22

3 Chemical and Physical Properties

Molecular Formula	C₃₂H₃₀FN₃O₁₀
Molecular Weight	635.6 g/mol
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	11
Exact Mass	635.19152232 g/mol
Monoisotopic Mass	635.19152232 g/mol
Topological Polar Surface Area	194 Å²
Heavy Atom Count	46
Formal Charge	0
Complexity	924
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Indication

* Renal Cell Carcinoma (RCC):

Cabometyx is indicated as monotherapy for the treatment of advanced renal cell carcinoma (RCC):

- in treatment-nave adults with intermediate or poor risk,

- in adults following prior vascular endothelial growth factor (VEGF)-targeted therapy.

Cabometyx, in combination with nivolumab, is indicated for the first-line treatment of advanced renal cell carcinoma in adults.

* Hepatocellular Carcinoma (HCC):

Cabometyx is indicated as monotherapy for the treatment of hepatocellular carcinoma (HCC) in adults who have previously been treated with sorafenib.

5 Pharmacology and Biochemistry

5.1 ATC Code

L01EX07

API SUPPLIERS

01

Granules India Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI India 2024

Attending

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02

Sichuan Elixir Pharmaceuticals

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Saudi International Expo

Not Confirmed

Sichuan Elixir Pharmaceutical, a manufacturer of small molecule APIs & a CMO/CDMO service provider for anti-tumor characteristic APIs..

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China

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USDMF

CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

03

ChemWerth Inc

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Saudi International Expo

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ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

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04

Transo-Pharm USA LLC

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Saudi International Expo

Not Confirmed

TransoPharm USA works in the Sourcing and Management of Active Pharmaceutical Ingredients.

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05

LGM Pharma

U.S.A

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BioFlorida Conference

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06

Fermion Oy

Finland

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Bio-Europe 2024

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USDMF

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07

Dr. Reddy's Laboratories

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI India 2024

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DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

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08

Tagoor Laboratories

India

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09

Sichuan Elixir Pharmaceuticals

China

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Saudi International Expo

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Sichuan Elixir Pharmaceutical, a manufacturer of small molecule APIs & a CMO/CDMO service provider for anti-tumor characteristic APIs..

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China

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USDMF

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10

Dr. Reddy's Laboratories

India

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CPhI India 2024

Booth #RH.E02

DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

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USDMF

01

Sichuan Elixir Pharmaceutical Co Ltd

China

SupplySide West 2024

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Cabozantinib (s)-malate

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 39785

Submission : 2024-03-26

Status : Active

Type : II

02

Sichuan Elixir Pharmaceutical Co Ltd

China

SupplySide West 2024

Not Confirmed

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Cabozantinib Sulfate

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 39757

Submission : 2024-03-22

Status : Active

Type : II

03

Fermion Oy

Finland

Bio-Europe 2024

Attending

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Cabozantinib S-malate

GDUFA

DMF Review : Complete

Rev. Date : 2020-04-17

Pay. Date : 2020-02-27

DMF Number : 34437

Submission : 2020-02-25

Status : Active

Type : II

04

Dr Reddys Laboratories Ltd

India

CPhI India 2024

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Cabozantinib (s)-malate (form N-2)

GDUFA

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DMF Number : 39274

Submission : 2023-12-29

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05

Dr Reddys Laboratories Ltd

India

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Cabozantinib Intermediate (czt3)

GDUFA

DMF Review : N/A

Rev. Date :

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DMF Number : 39141

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Status : Active

Type : II

06

Dr Reddys Laboratories Ltd

India

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Cabozantinib Hydrochloride

GDUFA

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DMF Number : 38207

Submission : 2023-03-31

Status : Active

Type : II

07

Biocon Ltd

India

SupplySide West 2024

Not Confirmed

08

Msn Laboratories Private Ltd

India

SupplySide West 2024

Not Confirmed

09

Msn Laboratories Private Ltd

India

SupplySide West 2024

Not Confirmed

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Natco Pharma Ltd

India

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MSN Laboratories

India

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MSN Laboratories

India

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Dr Reddy’s Laboratories Limited

India

CPhI India 2024

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CABOZANTINIB

NDC Package Code : 71796-059

Start Marketing Date : 2023-03-31

End Marketing Date : 2024-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT

02

Ash Stevens LLC

U.S.A

India

SupplySide West 2024

Not Confirmed

07

Sterling Chemical Malta Ltd

Malta

SupplySide West 2024

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08

Sterling Chemical Malta Ltd

Malta

SupplySide West 2024

Not Confirmed

09

STERLING SPA

Italy

SupplySide West 2024

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Valary Lab Private Limited

Country

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API Reference Price

[{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1638383400,"product":"CABOZANTINIB (S)-MALATE","address":"MSN HOUSE, PLOT NO. C-24,INDUSTRIAL HYDERABAD","city":"HYDERABAD","supplier":"MSN LABORATORIES","supplierCountry":"INDIA","foreign_port":"SEOUL","customer":"BORYUNG PHARMACEUTICAL CO., LTD","customerCountry":"KOREA, REPUBLIC OF","quantity":"2.50","actualQuantity":"2.5","unit":"KGS","unitRateFc":"34000","totalValueFC":"82716.7","currency":"USD","unitRateINR":2495600,"date":"02-Dec-2021","totalValueINR":"6239000","totalValueInUsd":"82716.7","indian_port":"HYDERABAD AIR","hs_no":"29337990","bill_no":"6452083","productDescription":"API","marketType":"REGULATED MARKET","country":"KOREA,REPUBLIC OF","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"MSN HOUSE, PLOT NO. C-24,INDUSTRIAL HYDERABAD, HYDERABAD","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1642012200,"product":"CABOZANTINIB (S)-MALATE (TAX INV NO:1905","address":"MSN HOUSE, PLOT NO. C-24,INDUSTRIAL HYDERABAD","city":"HYDERABAD","supplier":"MSN LABORATORIES","supplierCountry":"INDIA","foreign_port":"HONG KONG","customer":"BIOBETTA PHARMACEUTICALS SHANGHAI","customerCountry":"HONG KONG","quantity":"4.50","actualQuantity":"4.5","unit":"KGS","unitRateFc":"18000","totalValueFC":"79819.1","currency":"USD","unitRateINR":1321333.3333333333,"date":"13-Jan-2022","totalValueINR":"5946000","totalValueInUsd":"79819.1","indian_port":"HYDERABAD AIR","hs_no":"29337990","bill_no":"7464169","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"HONG KONG","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"MSN HOUSE, PLOT NO. C-24,INDUSTRIAL HYDERABAD, HYDERABAD","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1690828200,"product":"CABOZANTINIB (S) MALATE","address":"MSN HOUSE PLOT NO. C-24INDUSTRI AL ESTATE SANATH NAGAR","city":"Hyderabad","supplier":"MSN LABORATORIES","supplierCountry":"INDIA","foreign_port":"NA","customer":"TO THE ORDER OF","customerCountry":"CHINA","quantity":"4.50","actualQuantity":"4.5","unit":"KGS","unitRateFc":"15955.1","totalValueFC":"70986.5","currency":"USD","unitRateINR":1306724.1459999999,"date":"01-Aug-2023","totalValueINR":"5880258.657","totalValueInUsd":"70986.5","indian_port":"HYDERABAD ICD","hs_no":"29337990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD ICD","supplierAddress":"MSN HOUSE PLOT NO. C-24INDUSTRI AL ESTATE SANATH NAGAR, Hyderabad","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1691001000,"product":"CABOZANTINIB (S) MALATE","address":"MSN HOUSE PLOT NO. C-24INDUSTRI AL ESTATE SANATH NAGAR","city":"Hyderabad","supplier":"MSN LABORATORIES","supplierCountry":"INDIA","foreign_port":"NA","customer":"TO THE ORDER OF","customerCountry":"CHINA","quantity":"4.50","actualQuantity":"4.5","unit":"KGS","unitRateFc":"15955.1","totalValueFC":"70986.5","currency":"USD","unitRateINR":1306724.1459999999,"date":"03-Aug-2023","totalValueINR":"5880258.657","totalValueInUsd":"70986.5","indian_port":"HYDERABAD ICD","hs_no":"29337990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD ICD","supplierAddress":"MSN HOUSE PLOT NO. C-24INDUSTRI AL ESTATE SANATH NAGAR, Hyderabad","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1717698600,"product":"CABOZANTINIB (S)-MALATE (FORM-S)","address":"MSN HOUSE, PLOT NO. C-24,","city":"HYDERABAD. AP","supplier":"MSN LABORATORIES","supplierCountry":"INDIA","foreign_port":"SEOUL - INCHEON INT\\'","customer":"BORYUNG CORPORATION","customerCountry":"REPUBLIC OF KOREA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"25000","totalValueFC":"24736.6","currency":"USD","unitRateINR":2065000,"date":"07-Jun-2024","totalValueINR":"2065000","totalValueInUsd":"24736.6","indian_port":"Hyderabad Air","hs_no":"29337990","bill_no":"1503900","productDescription":"API","marketType":"REGULATED MARKET","country":"REPUBLIC OF KOREA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"MSN HOUSE, PLOT NO. C-24,, HYDERABAD. AP","customerAddress":""}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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Drugs in Development

01 Ipsen

France

SupplySide West 2024

Not Confirmed

02 Ipsen

France

SupplySide West 2024

Not Confirmed

03 Exelixis

U.S.A

U.S.A

SupplySide West 2024

Not Confirmed

10 Exelixis

U.S.A

SupplySide West 2024

Not Confirmed

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INTERMEDIATES SUPPLIERS

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FDF Dossiers

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FDA Orange Book

01

TEVA PHARMS INC

Israel

U.S.A

U.S.A

SupplySide West 2024

Not Confirmed

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Europe

01

Ipsen Pharma

France

Country

SupplySide West 2024

Not Confirmed

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Canada

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Australia

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South Africa

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Listed Dossiers

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - CAPSULE;ORAL - EQ 20MG BASE

USFDA APPLICATION NUMBER - 203756

DOSAGE - CAPSULE;ORAL - EQ 80MG BASE

USFDA APPLICATION NUMBER - 203756

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Excipients by Applications

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Coating Systems & Additives

Fillers, Diluents & Binders

Disintegrants & Superdisintegrants

Controlled & Modified Release

Direct Compression

Thickeners and Stabilizers

Lubricants & Glidants

Film Formers & Plasticizers

Granulation

Co-Processed Excipients

Empty Capsules

Coloring Agents

Emulsifying Agents

Vegetarian Capsules

API Stability Enhancers

Taste Masking

Topical

Solubilizers

Rheology Modifiers

Chewable & Orodispersible Aids

Parenteral

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Global Sales Information

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US Medicaid Prescriptions

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Finished Drug Prices

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Annual Reports

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Market Place

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APIs

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FDF DOSSIERS

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Patents & EXCLUSIVITIES

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US Patents

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US Exclusivities

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REF. STANDARDS & IMPURITIES

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Others

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ABOUT THIS PAGE

Find Cabozantinib manufacturers, exporters & distributors on PharmaCompass

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CHEMISTRY

Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

31 API Suppliers

11 USDMF

2 EU WC

2 KDMF

10 NDC API

25 Listed Suppliers

$ API Reference Price

DEVELOPMENTS

69 Drugs in Development

INTERMEDIATES

16 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

44 FDF Dossiers

8 FDA Orange Book

11 Europe

3 Canada

12 Australia

3 South Africa

7 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

CAPSULE;ORAL - EQ 20MG BASE

CAPSULE;ORAL - EQ 80MG BASE

RELATED EXCIPIENT COMPANIES

1 SPI Pharma

8 DKSH

1 Jai Radhe Sales

8 Gangwal Healthcare

1 Nanjing Well Pharmaceutical

4 ACG Worldwide

7 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

4 BASF

10 Corel Pharma Chem

5 DFE Pharma

1 Finar

6 Gangwal Chemicals

5 Ideal Cures Pvt Ltd

2 Ingredion Pharma Solutions

21 Kerry

3 Kima Chemical

6 Lonza Capsugel

11 Microlex e.U

1 Novo Excipients

2 Pharmatrans-Sanaq

2 Pluviaendo

4 Prachin Chemical

1 Qianhao Chemical (Hebei) Co., Ltd

2 Qualicaps

14 Roquette

7 Seppic

4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

10 Sigachi Industries

2 The Dow Chemical Company

1 Valens Pharmachem

4 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

46 Coating Systems & Additives

36 Fillers, Diluents & Binders

24 Disintegrants & Superdisintegrants

20 Controlled & Modified Release

19 Direct Compression

19 Thickeners and Stabilizers

15 Lubricants & Glidants

12 Film Formers & Plasticizers

12 Granulation

9 Co-Processed Excipients

9 Empty Capsules

5 Coloring Agents

5 Emulsifying Agents

4 Vegetarian Capsules

4 API Stability Enhancers

4 Taste Masking

4 Topical

3 Solubilizers

3 Rheology Modifiers