Find Cafedrine manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Norephendrinetheophylline, 58166-83-9, Cafedrinum, 14535-83-2, 7-[2-[(1-hydroxy-1-phenylpropan-2-yl)amino]ethyl]-1,3-dimethylpurine-2,6-dione, Cafedrine (ban)
Molecular Formula
C18H23N5O3
Molecular Weight
357.4  g/mol
InChI Key
UJSKUDDDPKGBJY-UHFFFAOYSA-N

Cafedrine
1 2D Structure

Cafedrine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
7-[2-[(1-hydroxy-1-phenylpropan-2-yl)amino]ethyl]-1,3-dimethylpurine-2,6-dione
2.1.2 InChI
InChI=1S/C18H23N5O3/c1-12(15(24)13-7-5-4-6-8-13)19-9-10-23-11-20-16-14(23)17(25)22(3)18(26)21(16)2/h4-8,11-12,15,19,24H,9-10H2,1-3H3
2.1.3 InChI Key
UJSKUDDDPKGBJY-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(C(C1=CC=CC=C1)O)NCCN2C=NC3=C2C(=O)N(C(=O)N3C)C
2.2 Synonyms
2.2.1 MeSH Synonyms

1. 7-(2-(1-methyl-2-hydroxy-2-phenylethylamino)ethyl)theophylline

2. Cafedrine Hydrochloride

3. Norephendrinetheophylline

4. Norephendrinetheophylline Mono-hydrochloride, (r-(r*,s*))-isomer

2.2.2 Depositor-Supplied Synonyms

1. Norephendrinetheophylline

2. 58166-83-9

3. Cafedrinum

4. 14535-83-2

5. 7-[2-[(1-hydroxy-1-phenylpropan-2-yl)amino]ethyl]-1,3-dimethylpurine-2,6-dione

6. Cafedrine (ban)

7. Schembl147271

8. Chembl2104207

9. Dtxsid50866678

10. 7-(2-(1-methyl-2-hydroxy-2-phenylethylamino)ethyl)theophylline Monohydrochloride

11. D07151

12. 7-[2-(2-hydroxy-1 Methyl-2-phenylethyl-amino)ethyl]theophylline

13. 1h-purine-2,6-dione, 3,7-dihydro-7-(2-((2-hydroxy-1-methyl-2-phenylethyl)amino)ethyl)-1,3-dimethyl- (van)

2.3 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 357.4 g/mol
Molecular Formula C18H23N5O3
XLogP30.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass357.18008961 g/mol
Monoisotopic Mass357.18008961 g/mol
Topological Polar Surface Area90.7 Ų
Heavy Atom Count26
Formal Charge0
Complexity525
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antihypertensive Agents

Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)


Vasodilator Agents

Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)


4.2 ATC Code

C - Cardiovascular system

C01 - Cardiac therapy

C01C - Cardiac stimulants excl. cardiac glycosides

C01CA - Adrenergic and dopaminergic agents

C01CA21 - Cafedrine


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Looking for 58166-83-9 / Cafedrine API manufacturers, exporters & distributors?

Cafedrine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Cafedrine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Cafedrine manufacturer or Cafedrine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Cafedrine manufacturer or Cafedrine supplier.

PharmaCompass also assists you with knowing the Cafedrine API Price utilized in the formulation of products. Cafedrine API Price is not always fixed or binding as the Cafedrine Price is obtained through a variety of data sources. The Cafedrine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Cafedrine

Synonyms

Norephendrinetheophylline, 58166-83-9, Cafedrinum, 14535-83-2, 7-[2-[(1-hydroxy-1-phenylpropan-2-yl)amino]ethyl]-1,3-dimethylpurine-2,6-dione, Cafedrine (ban)

Cas Number

58166-83-9

Cafedrine Manufacturers

A Cafedrine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Cafedrine, including repackagers and relabelers. The FDA regulates Cafedrine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Cafedrine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Cafedrine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Cafedrine Suppliers

A Cafedrine supplier is an individual or a company that provides Cafedrine active pharmaceutical ingredient (API) or Cafedrine finished formulations upon request. The Cafedrine suppliers may include Cafedrine API manufacturers, exporters, distributors and traders.

click here to find a list of Cafedrine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Cafedrine GMP

Cafedrine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Cafedrine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Cafedrine GMP manufacturer or Cafedrine GMP API supplier for your needs.

Cafedrine CoA

A Cafedrine CoA (Certificate of Analysis) is a formal document that attests to Cafedrine's compliance with Cafedrine specifications and serves as a tool for batch-level quality control.

Cafedrine CoA mostly includes findings from lab analyses of a specific batch. For each Cafedrine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Cafedrine may be tested according to a variety of international standards, such as European Pharmacopoeia (Cafedrine EP), Cafedrine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Cafedrine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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