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    Also known as: 5743-28-2, Calcium l-ascorbate dihydrate, Calcium ascorbate dihydrate, Calcium ascorbate (usp), Calcium ascorbate [usp], 183e4w213w
    Molecular Formula
    C12H18CaO14
    Molecular Weight
    426.34  g/mol
    InChI Key
    RGJHWLDSRIHFKY-FWCDDDAWSA-L
    FDA UNII
    183E4W213W
    Calcium Ascorbate
    1 2D Structure

    Calcium Ascorbate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    calcium;(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-hydroxy-5-oxo-2H-furan-4-olate;dihydrate
    2.1.2 InChI
    InChI=1S/2C6H8O6.Ca.2H2O/c2*7-1-2(8)5-3(9)4(10)6(11)12-5;;;/h2*2,5,7-10H,1H2;;2*1H2/q;;+2;;/p-2/t2*2-,5+;;;/m00.../s1
    2.1.3 InChI Key
    RGJHWLDSRIHFKY-FWCDDDAWSA-L
    2.1.4 Canonical SMILES
    C(C(C1C(=C(C(=O)O1)[O-])O)O)O.C(C(C1C(=C(C(=O)O1)[O-])O)O)O.O.O.[Ca+2]
    2.1.5 Isomeric SMILES
    C([C@@H]([C@@H]1C(=C(C(=O)O1)[O-])O)O)O.C([C@@H]([C@@H]1C(=C(C(=O)O1)[O-])O)O)O.O.O.[Ca+2]
    2.2 Other Identifiers
    2.2.1 UNII
    183E4W213W
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Ester C

    2.3.2 Depositor-Supplied Synonyms

    1. 5743-28-2

    2. Calcium L-ascorbate Dihydrate

    3. Calcium Ascorbate Dihydrate

    4. Calcium Ascorbate (usp)

    5. Calcium Ascorbate [usp]

    6. 183e4w213w

    7. Ester-c

    8. Ins No.302

    9. Calcium (r)-5-((s)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5h)-one Salt Dihydrate

    10. Ins-302

    11. Vitamin C (as Calcium Ascorbate)

    12. Calcium Ascorbate [usan]

    13. E-302

    14. Unii-183e4w213w

    15. Dsstox_cid_27687

    16. Dsstox_rid_82503

    17. Dsstox_gsid_47687

    18. L-ascorbic Acid, Calcium Salt (2:1), Dihydrate

    19. Calcium Ascorbate [ii]

    20. Calcium Ascorbate [fcc]

    21. Calcium Ascorbate [inci]

    22. Chembl3184533

    23. Dtxsid3047687

    24. Calcium Ascorbate [vandf]

    25. Calcium Ascorbate [usp-rs]

    26. Tox21_303536

    27. Acetic Acid, Calcium Salt, Dihydrate

    28. Mfcd00149216

    29. Calcium Ascorbate [ep Monograph]

    30. Calcium Ascorbate [usp Monograph]

    31. Ncgc00257476-01

    32. E302

    33. Cas-5743-28-2

    34. Calcium Ascorbate Dihydrate [who-dd]

    35. L(+)-ascorbicacidcalciumsaltdihydrate

    36. D02293

    37. Q283033

    38. Calcium;(2r)-2-[(1s)-1,2-dihydroxyethyl]-3-hydroxy-5-oxo-2h-furan-4-olate;dihydrate

    2.4 Create Date
    2011-12-26
    3 Chemical and Physical Properties
    Molecular Weight 426.34 g/mol
    Molecular Formula C12H18CaO14
    Hydrogen Bond Donor Count8
    Hydrogen Bond Acceptor Count14
    Rotatable Bond Count4
    Exact Mass426.0322461 g/mol
    Monoisotopic Mass426.0322461 g/mol
    Topological Polar Surface Area222 Ų
    Heavy Atom Count27
    Formal Charge0
    Complexity232
    Isotope Atom Count0
    Defined Atom Stereocenter Count4
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count5
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Antioxidants

    Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues. (See all compounds classified as Antioxidants.)

    Vitamins

    Organic substances that are required in small amounts for maintenance and growth, but which cannot be manufactured by the human body. (See all compounds classified as Vitamins.)

    API Reference Price

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I. D. C.,,TARA PUR, BOISAR,","city":"THANE,MAHARASHTRA","supplier":"KENKO CORPORATION","supplierCountry":"CHINA","foreign_port":"NA","customer":"BAJAJ HEALTHCARE","customerCountry":"INDIA","quantity":"5000.00","actualQuantity":"5000","unit":"KGS","unitRateFc":"7.5","totalValueFC":"37894.5","currency":"USD","unitRateINR":"567.8","date":"18-Oct-2021","totalValueINR":"2838750","totalValueInUsd":"37894.5","indian_port":"JNPT","hs_no":"29362990","bill_no":"5879625","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"N - 216 & N-217, M. I. D. C.,,TARA PUR, BOISAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1644777000,"product":"CALCIUM ASCORBATE- UNITED STATES","address":"B 502, DELPHI BUILDING, ORCHARD AVE HIRANANDANI BUSINESS PARK, POWAI,","city":"MUMBAI","supplier":"ROYAL DSM","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"ROYAL DSM","customerCountry":"INDIA","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"2084","totalValueFC":"8340.8","currency":"INR","unitRateINR":"2084","date":"14-Feb-2022","totalValueINR":"625200","totalValueInUsd":"8340.8","indian_port":"BOMBAY AIR","hs_no":"29362700","bill_no":"7480519","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"B 502, DELPHI BUILDING, ORCHARD AVE HIRANANDANI BUSINESS PARK, POWAI,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1663007400,"product":"CALCIUM ASCORBATE- UNITED STATES","address":"B 502, DELPHI BUILDING, ORCHARD AVE HIRANANDANI BUSINESS PARK, POWAI,","city":"MUMBAI","supplier":"ROYAL DSM","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"ROYAL DSM","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"2819.6","totalValueFC":"3518.3","currency":"INR","unitRateINR":"2819.6","date":"13-Sep-2022","totalValueINR":"281957","totalValueInUsd":"3518.3","indian_port":"BOMBAY AIR","hs_no":"29362700","bill_no":"2411314","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"B 502, DELPHI BUILDING, ORCHARD AVE HIRANANDANI BUSINESS PARK, POWAI,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1670265000,"product":"CALCIUM ASCORBATE -UNITED STATES","address":"B 502, DELPHI BUILDING, ORCHARD AVE HIRANANDANI BUSINESS PARK, POWAI,","city":"MUMBAI","supplier":"ROYAL DSM","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"ROYAL DSM","customerCountry":"INDIA","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"2799.6","totalValueFC":"10191.8","currency":"INR","unitRateINR":"2799.6","date":"06-Dec-2022","totalValueINR":"839871","totalValueInUsd":"10191.8","indian_port":"BOMBAY AIR","hs_no":"29362400","bill_no":"3616055","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"B 502, DELPHI BUILDING, ORCHARD AVE HIRANANDANI BUSINESS PARK, POWAI,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1678818600,"product":"CALCIUM ASCORBATE -UNITED STATES","address":"B 502, DELPHI BUILDING, ORCHARD AVE HIRANANDANI BUSINESS PARK, POWAI,","city":"MUMBAI","supplier":"ROYAL DSM","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"ROYAL DSM","customerCountry":"INDIA","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"2784.6","totalValueFC":"10156.4","currency":"INR","unitRateINR":"2784.6","date":"15-Mar-2023","totalValueINR":"835371","totalValueInUsd":"10156.4","indian_port":"BOMBAY AIR","hs_no":"29362400","bill_no":"5061347","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"B 502, DELPHI BUILDING, ORCHARD AVE HIRANANDANI BUSINESS PARK, POWAI,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1701801000,"product":"CALCIUM ASCORBATE -UNITED STATES","address":"401 4TH FL WINDSOR HOUSE CST RD","city":"MUMBAI, MAHARASHTRA.","supplier":"ROYAL DSM","supplierCountry":"UNITED STATES","foreign_port":"NEW YORK - JOHN F. K","customer":"ROYAL DSM","customerCountry":"INDIA","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"2662.6","totalValueFC":"9595.6","currency":"INR","unitRateINR":"2662.6","date":"06-Dec-2023","totalValueINR":"798771","totalValueInUsd":"9595.6","indian_port":"Bombay Air","hs_no":"29362400","bill_no":"9092855","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NEW YORK - JOHN F. K","supplierAddress":"30 PASIR PANJANG ROAD #13-31, MAPLETREE BUSINESS CITY, Singapore - 117440, , Singapore Singapore","customerAddress":"401 4TH FL WINDSOR HOUSE CST RD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1713551400,"product":"CALCIUM ASCORBATE -UNITED STATES","address":"401 4TH FL WINDSOR HOUSE CST RD","city":"MUMBAI, MAHARASHTRA.","supplier":"ROYAL DSM","supplierCountry":"UNITED STATES","foreign_port":"NEW YORK - JOHN F. K","customer":"ROYAL DSM","customerCountry":"INDIA","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"2675.8","totalValueFC":"9612.9","currency":"INR","unitRateINR":"2675.8","date":"20-Apr-2024","totalValueINR":"802749","totalValueInUsd":"9612.9","indian_port":"Bombay Air","hs_no":"29362400","bill_no":"3109294","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NEW YORK - JOHN F. K","supplierAddress":"30 PASIR PANJANG ROAD #13-31, MAPLETREE BUSINESS CITY, Singapore - 117440, , Singapore Singapore","customerAddress":"401 4TH FL WINDSOR HOUSE CST RD"}]
    26-Jan-2021
    31-Jul-2024
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    ABOUT THIS PAGE

    Calcium Ascorbate Manufacturers

    A Calcium Ascorbate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Calcium Ascorbate, including repackagers and relabelers. The FDA regulates Calcium Ascorbate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Calcium Ascorbate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Calcium Ascorbate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Calcium Ascorbate Suppliers

    A Calcium Ascorbate supplier is an individual or a company that provides Calcium Ascorbate active pharmaceutical ingredient (API) or Calcium Ascorbate finished formulations upon request. The Calcium Ascorbate suppliers may include Calcium Ascorbate API manufacturers, exporters, distributors and traders.

    click here to find a list of Calcium Ascorbate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Calcium Ascorbate CEP

    A Calcium Ascorbate CEP of the European Pharmacopoeia monograph is often referred to as a Calcium Ascorbate Certificate of Suitability (COS). The purpose of a Calcium Ascorbate CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Calcium Ascorbate EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Calcium Ascorbate to their clients by showing that a Calcium Ascorbate CEP has been issued for it. The manufacturer submits a Calcium Ascorbate CEP (COS) as part of the market authorization procedure, and it takes on the role of a Calcium Ascorbate CEP holder for the record. Additionally, the data presented in the Calcium Ascorbate CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Calcium Ascorbate DMF.

    A Calcium Ascorbate CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Calcium Ascorbate CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Calcium Ascorbate suppliers with CEP (COS) on PharmaCompass.

    Calcium Ascorbate GMP

    Calcium Ascorbate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Calcium Ascorbate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Calcium Ascorbate GMP manufacturer or Calcium Ascorbate GMP API supplier for your needs.

    Calcium Ascorbate CoA

    A Calcium Ascorbate CoA (Certificate of Analysis) is a formal document that attests to Calcium Ascorbate's compliance with Calcium Ascorbate specifications and serves as a tool for batch-level quality control.

    Calcium Ascorbate CoA mostly includes findings from lab analyses of a specific batch. For each Calcium Ascorbate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Calcium Ascorbate may be tested according to a variety of international standards, such as European Pharmacopoeia (Calcium Ascorbate EP), Calcium Ascorbate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Calcium Ascorbate USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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