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ACTIVE PHARMA INGREDIENTS

8 API Suppliers, 1 CEP/COS, 7 Listed Suppliers, $ API Reference Price

8 API Suppliers
1 CEP/COS
7 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

3 FDF Dossiers, 3 South Africa

3 FDF Dossiers
3 South Africa

RELATED EXCIPIENT COMPANIES

3 Rochem International Inc, 6 SPI Pharma, 2 Seqens, 8 DKSH, 2 Jai Radhe Sales, 3 Boai NKY Pharmaceuticals Ltd, 11 Gangwal Healthcare, 3 Nanjing Well Pharmaceutical, 1 Pfanstiehl, 4 ACG Worldwide, 8 Actylis, 1 Aeon Procare, 7 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 12 BASF, 11 Corel Pharma Chem, 3 DFE Pharma, 1 Finar, 11 Gangwal Chemicals, 7 Ideal Cures Pvt Ltd, 3 Ingredion Pharma Solutions, 17 Kerry, 4 Kima Chemical, 6 Lonza Capsugel, 10 Microlex e.U, 1 Nanjing Bold Chemical, 2 Nomisma Healthcare, 2 Novo Excipients, 1 Pharmatrans-Sanaq, 5 Pluviaendo, 3 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 2 Qualicaps, 25 Roquette, 13 Seppic, 6 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Shanghai Welltone Material Technology Co., Ltd, 1 Shijiazhuang Huaxu Pharmaceutical, 10 Sigachi Industries, 3 The Dow Chemical Company, 1 Ulanqab Kema New Material, 3 Vasa Pharmachem, 1 Zhejiang Huakang Pharmaceutical

relatedExcipients
3 Rochem International Inc
6 SPI Pharma
2 Seqens
8 DKSH
2 Jai Radhe Sales
3 Boai NKY Pharmaceuticals Ltd
11 Gangwal Healthcare
3 Nanjing Well Pharmaceutical
1 Pfanstiehl
4 ACG Worldwide
8 Actylis
1 Aeon Procare
7 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd
12 BASF
11 Corel Pharma Chem
3 DFE Pharma
1 Finar
11 Gangwal Chemicals
7 Ideal Cures Pvt Ltd
3 Ingredion Pharma Solutions
17 Kerry
4 Kima Chemical
6 Lonza Capsugel
10 Microlex e.U
1 Nanjing Bold Chemical
2 Nomisma Healthcare
2 Novo Excipients
1 Pharmatrans-Sanaq
5 Pluviaendo
3 Prachin Chemical
1 Qianhao Chemical (Hebei) Co., Ltd
2 Qualicaps
25 Roquette
13 Seppic
6 Shanghai Shenmei Pharmaceutical Technology Co., Ltd
1 Shanghai Welltone Material Technology Co., Ltd
1 Shijiazhuang Huaxu Pharmaceutical
10 Sigachi Industries
3 The Dow Chemical Company
1 Ulanqab Kema New Material
3 Vasa Pharmachem
1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

55 Fillers, Diluents & Binders, 53 Coating Systems & Additives, 30 Controlled & Modified Release, 26 Thickeners and Stabilizers, 25 Direct Compression, 20 Disintegrants & Superdisintegrants, 19 Film Formers & Plasticizers, 17 Lubricants & Glidants, 17 Solubilizers, 15 Parenteral, 15 Co-Processed Excipients, 15 Taste Masking, 14 Topical, 14 Granulation, 9 Emulsifying Agents, 9 Empty Capsules, 8 Chewable & Orodispersible Aids, 8 API Stability Enhancers, 5 Coloring Agents, 4 Rheology Modifiers, 4 Vegetarian Capsules, 2 Surfactant & Foaming Agents, 1 Soft Gelatin

MARKET PLACE

8 APIs, 1 EXCIPIENTS

marketPlace
8 APIs
1 EXCIPIENTS

REF. STANDARDS & IMPURITIES

1 USP , 1 Others

otherSolutions
1 USP
1 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 15

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

225 RELATED EXCIPIENT COMPANIES

385EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 5743-28-2, Calcium l-ascorbate dihydrate, Calcium ascorbate dihydrate, Calcium ascorbate (usp), Calcium ascorbate [usp], 183e4w213w

Molecular Formula

C₁₂H₁₈CaO₁₄

Molecular Weight

426.34 g/mol

InChI Key

RGJHWLDSRIHFKY-FWCDDDAWSA-L

FDA UNII

183E4W213W

1 2D Structure

Calcium Ascorbate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

calcium;(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-hydroxy-5-oxo-2H-furan-4-olate;dihydrate

2.1.2 InChI

InChI=1S/2C6H8O6.Ca.2H2O/c2*7-1-2(8)5-3(9)4(10)6(11)12-5;;;/h2*2,5,7-10H,1H2;;2*1H2/q;;+2;;/p-2/t2*2-,5+;;;/m00.../s1

2.1.3 InChI Key

RGJHWLDSRIHFKY-FWCDDDAWSA-L

2.1.4 Canonical SMILES

C(C(C1C(=C(C(=O)O1)[O-])O)O)O.C(C(C1C(=C(C(=O)O1)[O-])O)O)O.O.O.[Ca+2]

2.1.5 Isomeric SMILES

C([C@@H]([C@@H]1C(=C(C(=O)O1)[O-])O)O)O.C([C@@H]([C@@H]1C(=C(C(=O)O1)[O-])O)O)O.O.O.[Ca+2]

2.2 Other Identifiers

2.2.1 UNII

183E4W213W

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Ester C

2.3.2 Depositor-Supplied Synonyms

1. 5743-28-2

2. Calcium L-ascorbate Dihydrate

3. Calcium Ascorbate Dihydrate

4. Calcium Ascorbate (usp)

5. Calcium Ascorbate [usp]

6. 183e4w213w

7. Ester-c

8. Ins No.302

9. Calcium (r)-5-((s)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5h)-one Salt Dihydrate

10. Ins-302

11. Vitamin C (as Calcium Ascorbate)

12. Calcium Ascorbate [usan]

13. E-302

14. Unii-183e4w213w

15. Dsstox_cid_27687

16. Dsstox_rid_82503

17. Dsstox_gsid_47687

18. L-ascorbic Acid, Calcium Salt (2:1), Dihydrate

19. Calcium Ascorbate [ii]

20. Calcium Ascorbate [fcc]

21. Calcium Ascorbate [inci]

22. Chembl3184533

23. Dtxsid3047687

24. Calcium Ascorbate [vandf]

25. Calcium Ascorbate [usp-rs]

26. Tox21_303536

27. Acetic Acid, Calcium Salt, Dihydrate

28. Mfcd00149216

29. Calcium Ascorbate [ep Monograph]

30. Calcium Ascorbate [usp Monograph]

31. Ncgc00257476-01

32. E302

33. Cas-5743-28-2

34. Calcium Ascorbate Dihydrate [who-dd]

35. L(+)-ascorbicacidcalciumsaltdihydrate

36. D02293

37. Q283033

38. Calcium;(2r)-2-[(1s)-1,2-dihydroxyethyl]-3-hydroxy-5-oxo-2h-furan-4-olate;dihydrate

2.4 Create Date

2011-12-26

3 Chemical and Physical Properties

Molecular Formula	C₁₂H₁₈CaO₁₄
Molecular Weight	426.34 g/mol
Hydrogen Bond Donor Count	8
Hydrogen Bond Acceptor Count	14
Rotatable Bond Count	4
Exact Mass	426.0322461 g/mol
Monoisotopic Mass	426.0322461 g/mol
Topological Polar Surface Area	222 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	232
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	5

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Antioxidants

Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues. (See all compounds classified as Antioxidants.)

Vitamins

Organic substances that are required in small amounts for maintenance and growth, but which cannot be manufactured by the human body. (See all compounds classified as Vitamins.)

API SUPPLIERS

01

BASF

Germany

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

ASC 2024

Not Confirmed

02

Northeast Pharmaceutical Group Co ...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

ASC 2024

Not Confirmed

03

Royal DSM

Netherlands

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

ASC 2024

Not Confirmed

04

West Bengal Chemicals Industries

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

ASC 2024

Not Confirmed

05

India Phosphate

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

ASC 2024

Not Confirmed

06

Sneha Medicare Pvt Ltd

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

ASC 2024

Not Confirmed

07

CSPC Pharmaceutical Group

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

ASC 2024

Not Confirmed

08

Bajaj Healthcare

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

ASC 2024

Not Confirmed

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

CEP/COS

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Listed Suppliers

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

API Reference Price

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","customerCountry":"GERMANY","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"19","totalValueFC":"9386.6","currency":"USD","unitRateINR":1557.6900000000001,"date":"29-Feb-2024","totalValueINR":"778845","totalValueInUsd":"9386.6","indian_port":"Bombay Air","hs_no":"29362990","bill_no":"7951383","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"N - 216 N-217, M. I. D. 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K","customer":"ROYAL DSM","customerCountry":"INDIA","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"2668","totalValueFC":"9542.5","currency":"INR","unitRateINR":"2668","date":"25-Aug-2024","totalValueINR":"800412","totalValueInUsd":"9542.5","indian_port":"Bombay Air","hs_no":"29362400","bill_no":"5241558","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NEW YORK - JOHN F. K","supplierAddress":"30 PASIR PANJANG ROAD #13-31, MAPLETREE BUSINESS CITY, Singapore - 117440, , Singapore Singapore","customerAddress":"401 4TH FL WINDSOR HOUSE CST RD"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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ABOUT THIS PAGE

List of Related Excipient Companies and Suppliers of Calcium Ascorbate by Sigachi Industries on PharmaCompass.com

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CHEMISTRY

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ACTIVE PHARMA INGREDIENTS

8 API Suppliers

1 CEP/COS

7 Listed Suppliers

$ API Reference Price

FINISHED DOSAGE FORMULATIONS

3 FDF Dossiers

3 South Africa

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EXCIPIENTS BY APPLICATIONS

55 Fillers, Diluents & Binders

53 Coating Systems & Additives

30 Controlled & Modified Release

26 Thickeners and Stabilizers

25 Direct Compression

20 Disintegrants & Superdisintegrants

19 Film Formers & Plasticizers

17 Lubricants & Glidants

17 Solubilizers

15 Parenteral

15 Co-Processed Excipients

15 Taste Masking

14 Topical

14 Granulation

9 Emulsifying Agents

9 Empty Capsules

8 Chewable & Orodispersible Aids

8 API Stability Enhancers

5 Coloring Agents

4 Rheology Modifiers

4 Vegetarian Capsules

2 Surfactant & Foaming Agents

1 Soft Gelatin