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Calcium Dobesilate

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ACTIVE PHARMA INGREDIENTS

5 API Suppliers, 9 KDMF, 5 Listed Suppliers, $ API Reference Price

5 API Suppliers
9 KDMF
5 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

8 FDF Dossiers, 5 Europe, 3 Listed Dossiers

8 FDF Dossiers
5 Europe
3 Listed Dossiers

GLOBAL SALES INFORMATION

5 Finished Drug Prices

globalSalesInformation
5 Finished Drug Prices

MARKET PLACE

10 APIs, 1 FDF Dossiers

marketPlace
10 APIs
1 FDF Dossiers

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 35

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

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US Patents

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Health Canada Patents

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Annual Reports (USD Million)

Finished Drug Prices

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Chemistry

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Also known as: 20123-80-2, Dexium, Dobesilate calcium, Doxium, Calcium 2,5-dihydroxybenzenesulfonate, Hydroquinone calcium sulfonate

Molecular Formula

C₁₂H₁₀CaO₁₀S₂

Molecular Weight

418.4 g/mol

InChI Key

QGNBTYAQAPLTMX-UHFFFAOYSA-L

FDA UNII

5921X1560Q

A drug used to reduce hemorrhage in diabetic retinopathy.

1 2D Structure

Calcium Dobesilate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

calcium;2,5-dihydroxybenzenesulfonate

2.1.2 InChI

InChI=1S/2C6H6O5S.Ca/c2*7-4-1-2-5(8)6(3-4)12(9,10)11;/h2*1-3,7-8H,(H,9,10,11);/q;;+2/p-2

2.1.3 InChI Key

QGNBTYAQAPLTMX-UHFFFAOYSA-L

2.1.4 Canonical SMILES

C1=CC(=C(C=C1O)S(=O)(=O)[O-])O.C1=CC(=C(C=C1O)S(=O)(=O)[O-])O.[Ca+2]

2.2 Other Identifiers

2.2.1 UNII

5921X1560Q

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 2,5 Dihydroxybenzenesulfonate

2. 2,5 Dihydroxybenzenesulfonic Acid

3. 2,5-dihydroxybenzenesulfonate

4. 2,5-dihydroxybenzenesulfonic Acid

5. Calcium Dobesilate (1:1)

6. Calcium Dobesilate Monoammonium Salt

7. Calcium Dobesilate Monopotassium Salt

8. Calcium, Dobesilate

9. Dexium

10. Dobesilate Calcium

11. Dobesilate, Calcium

12. Dobica

13. Doxium

2.3.2 Depositor-Supplied Synonyms

1. 20123-80-2

2. Dexium

3. Dobesilate Calcium

4. Doxium

5. Calcium 2,5-dihydroxybenzenesulfonate

6. Hydroquinone Calcium Sulfonate

7. Calcium Dobesilate [inn]

8. 205 E

9. Benzenesulfonic Acid, 2,5-dihydroxy-, Calcium Salt (2:1)

10. 2,5-dihydroxybenzenesulfonic Acid Calcium Salt

11. Calcium Doxybensylate

12. Calcii Dobesilas

13. 205-e

14. 5921x1560q

15. Calcium Dobesilate (inn)

16. Dobesilato Calcico

17. Doxi-om

18. Dobesilate De Calcium

19. Calcium Bis(2,5-dihydroxybenzenesulfonate)

20. Calcium Dobesilate Hydrate

21. Calciumdobesilate

22. Calcium Hydrochinonsulfonat

23. Dobesilato Calcio

24. Dobesilato Di Calcio [dcit]

25. Dobesilato Di Calcio

26. Calcii Dobesilas [inn-latin]

27. Dobesilato Calcio [inn-spanish]

28. Dobesilate De Calcium [inn-french]

29. Einecs 243-531-5

30. Calcium Bis(2,5-dihydroxybenzolsulfonat)

31. Unii-5921x1560q

32. Doxium (tn)

33. Calcium Dobesilate,(s)

34. Schembl148396

35. Benzenesulfonic Acid, 2,5-dihydroxy-, Calcium Salt

36. 2,5-dihydroxybenzenesulfonic Acid Calcium Salt (2:1)

37. Dobesilate Calcium [mi]

38. Chembl2106191

39. Exo-2-aminonorbornane99

40. Dtxsid60173946

41. Bcp13786

42. Calcium Dobesilate [who-dd]

43. Akos005267175

44. Dobesilate Calcium, >=98% (hplc)

45. Calcium 2,5-bis(oxidanyl)benzenesulfonate

46. Db-045100

47. Hy-111603

48. Cs-0088365

49. Ft-0625554

50. Calcium 2,5-dihydroxybenzenesulphonate

51. D07427

52. D70205

53. A814261

54. J-013032

55. Q5018825

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₁₂H₁₀CaO₁₀S₂
Molecular Weight	418.4 g/mol
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	0
Exact Mass	417.9341297 g/mol
Monoisotopic Mass	417.9341297 g/mol
Topological Polar Surface Area	212 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	228
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	3

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Hemostatics

Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure. (See all compounds classified as Hemostatics.)

4.2 ATC Code

C - Cardiovascular system

C05 - Vasoprotectives

C05B - Antivaricose therapy

C05BX - Other sclerosing agents

C05BX01 - Calcium dobesilate

API SUPPLIERS

01

Jai Radhe Sales

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

AES 2024

Not Confirmed

Jai Radhe Sales is your partner for all your sourcing needs.

Contact Supplier

India

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

02

Global Calcium

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

AES 2024

Not Confirmed

03

Northern Synthesis

Latvia

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

AES 2024

Not Confirmed

04

Chemignition Laboratory

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

AES 2024

Not Confirmed

05

Wanbang Biopharmaceuticals

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

AES 2024

Not Confirmed

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KDMF

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Listed Suppliers

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API Reference Price

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