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1. Buckytube
2. Buckytubes
3. Carbon Nanotube
4. Carbon Nanotubes
5. Nanoribbon
6. Nanoribbons
7. Nanotube, Carbon
8. Nanotubes, Carbon
1. 05105_fluka
2. 05110_fluka
3. 05112_fluka
4. 05113_fluka
5. 05120_fluka
6. 05123_fluka
7. 101239-80-9
8. 106907-70-4
9. 109766-76-9
10. 114680-00-1
11. 115344-49-5
12. 116788-82-0
13. 12424-49-6
14. 124760-06-1
15. 12751-41-6
16. 12768-98-8
17. 12789-22-9
18. 130960-03-1
19. 131640-45-4
20. 133136-50-2
21. 1333-86-4
22. 1343-03-9
23. 137322-21-5
24. 137906-62-8
25. 138464-41-2
26. 1399-57-1
27. 147335-73-7
28. 155660-93-8
29. 156854-02-3
30. 158271-80-8
31. 159251-18-0
32. 161551_sial
33. 16291-96-6
34. 16291-96-6 (parent)
35. 164973-65-3
36. 179607-25-1
37. 18002_riedel
38. 18002_supelco
39. 18006_riedel
40. 18008_riedel
41. 18008_sial
42. 181719-82-4
43. 182761-22-4
44. 186708-92-9
45. 186708-96-3
46. 208519-32-8
47. 208728-20-5
48. 208728-21-6
49. 214540-86-0
50. 22874_fluka
51. 22874_sial
52. 242233_sial
53. 242241_sial
54. 242268_sial
55. 242276_sial
56. 26837-67-2
57. 282863_aldrich
58. 282863_sial
59. 29204_fluka
60. 29204_sial
61. 29238_fluka
62. 292591_sial
63. 2p3vwu3h10
64. 308068-56-6
65. 326874-96-8
66. 329428_sial
67. 332461_aldrich
68. 332461_sial
69. 37196-29-5
70. 37265-44-4
71. 37265-48-8
72. 37771_fluka
73. 37771_sial
74. 37996_fluka
75. 37996_sial
76. 390127_sial
77. 39422-04-3
78. 39434-34-9
79. 39988_fluka
80. 3b4-2186
81. 429685-07-4
82. 484164_aldrich
83. 496537_aldrich
84. 496545_aldrich
85. 496553_aldrich
86. 496561_aldrich
87. 496588_aldrich
88. 496596_aldrich
89. 50814-81-8
90. 51127_fluka
91. 51127_sial
92. 519308_aldrich
93. 52623-24-2
94. 53095-52-6
95. 53663_fluka
96. 53663_sial
97. 53851-02-8
98. 55353-42-9
99. 55607-95-9
100. 56257-79-5
101. 56257-80-8
102. 56274-59-0
103. 566149-76-6
104. 56729-25-0
105. 56729-26-1
106. 572497_aldrich
107. 58517-29-6
108. 58899_fluka
109. 61512-59-2
110. 633100_aldrich
111. 636398_aldrich
112. 63661-31-4
113. 64365-11-3
114. 64365-11-3 (activated)
115. 64427-56-1
116. 64900-31-8
117. 65407-06-9
118. 67167-41-3
119. 675342_sial
120. 681225-93-4
121. 6c
122. 72343_fluka
123. 72343_sial
124. 72536-89-1
125. 72840-52-9
126. 73560-38-0
127. 7440-44-0
128. 75026-75-4
129. 76416-61-0
130. 76632-92-3
131. 7782-40-3
132. 7782-42-5
133. 798556-12-4
134. 798556-14-6
135. 79921-09-8
136. 81180-26-9
137. 82600-58-6
138. 82696-74-0
139. 82696-75-1
140. 82701-02-8
141. 82701-03-9
142. 82701-04-0
143. 82701-05-1
144. 82701-06-2
145. 82709-42-0
146. 83138-28-7
147. 83797-07-3
148. 84739-05-9
149. 857167-12-5
150. 87934-03-0
151. 89341_fluka
152. 89341_sial
153. 89440_aldrich
154. 89440_fluka
155. 90452-98-5
156. 90597-58-3
157. 93067_fluka
158. 93067_sial
159. 95681_fluka
160. 95681_sial
161. 96831_fluka
162. 96831_sial
163. 97708-44-6
164. 97793-37-8
165. 97876_fluka
166. 97876_sial
167. Ac1nuwbm
168. Acetylene Black
169. Acticarbone
170. Actidose
171. Activated Carbon
172. Activated Charcoal
173. Activated Charcoal Norit
174. Activated Charcoal Norit(r)
175. Activated Charcoal, Iodinated
176. Adsorba
177. Adsorbit
178. Aerodag G
179. Ag 1500
180. Ag 3 (adsorbent)
181. Ag 5
182. Ag 5 (adsorbent)
183. Agn-pc-0lquf1
184. Ak (adsorbent)
185. Akos015914131
186. Amoco Px 21
187. Animal Bone Charcoal
188. Anthrasorb
189. Aqua Nuchar
190. Aquadag
191. Ar 3
192. Aroflow
193. Arogen
194. Arotone
195. Arovel
196. Arrow
197. Art 2
198. As 1
199. At 20
200. Atj-s
201. Atj-s Graphite
202. Atlantic
203. Au 3
204. Bau
205. Bg 6080
206. Black 140
207. Black Kosmos 33
208. Black Lead
209. Black Pearls
210. Bone Charcoal
211. C
212. C.i. 77265
213. C.i. 77266
214. C.i. Pigment Black 10
215. C.i. Pigment Black 6
216. C.i. Pigment Black 7
217. C2194
218. C2764_sial
219. C2889_sial
220. C3014_sial
221. C3345_sial
222. C4386_sial
223. C5510_sial
224. C6289_sial
225. C9157_sial
226. Calcotone Black
227. Cancarb
228. Canesorb
229. Canlub
230. Carbo Activatus
231. Carbo Vegetabilis
232. Carbodis
233. Carbolac
234. Carbolac 1
235. Carbomet
236. Carbomix
237. Carbon Activated
238. Carbon Black
239. Carbon Black Bv And V
240. Carbon Black, Acetylene
241. Carbon Black, Channel
242. Carbon Black, Furnace
243. Carbon Black, Lamp
244. Carbon Black, Thermal
245. Carbon Nanotube
246. Carbon Nanotube, Single-walled
247. Carbon Powder
248. Carbon, Activate
249. Carbon, Activated
250. Carbon, Activated [un1362] [spontaneously Combustible]
251. Carbon, Amorphous
252. Carbon, Colloidal
253. Carbon, Vitreous
254. Carbon-12
255. Carbone
256. Carbonium
257. Carbono
258. Carbopol Extra
259. Carbopol M
260. Carbopol Z 4
261. Carbopol Z Extra
262. Carbosieve
263. Carbosorbit R
264. Caswell No. 161
265. Cb 50
266. Ccris 7235
267. Ccris 8681
268. Ccris 9467
269. Cecarbon
270. Ceylon Black Lead
271. Cf 8
272. Cf 8 (carbon)
273. Channel Black
274. Char, From Refuse Burner
275. Charbon
276. Charcoal
277. Charcoal Bone
278. Charcoal Activated
279. Charcoal Activated Norit
280. Charcoal Activated Norit(r)
281. Charcoal Bone
282. Charcoal, Activated
283. Charcoal, Activated [usp]
284. Charcoal, Except Activated
285. Charcodote
286. Chebi:27594
287. Ci 77266
288. Ci Pigment Black 7
289. Ck3
290. Clf Ii
291. Cmb 200
292. Cmb 50
293. Coke Powder
294. Colgon Bpl
295. Colgon Pcb 12x30
296. Colgon Pcb-d
297. Collocarb
298. Columbia Carbon
299. Columbia Lck
300. Conductex
301. Conductex 900
302. Continex
303. Corax A
304. Corax P
305. Cpb 5000
306. Croflex
307. Crolac
308. Cuz 3
309. Cwn 2
310. D&c Black No. 2
311. D002244
312. D006108
313. Darco
314. Dc 2
315. Degussa
316. Delussa Black Fw
317. Diamond
318. Durex O
319. Eagle Germantown
320. Eg 0
321. Einecs 215-609-9
322. Einecs 231-153-3
323. Einecs 231-953-2
324. Einecs 231-955-3
325. Einecs 264-846-4
326. Electrographite
327. Elf 78
328. Elftex
329. Epa Pesticide Chemical Code 016001
330. Essex
331. Excelsior
332. Exp-f
333. Explosion Acetylene Black
334. Explosion Black
335. Farbruss
336. Fecto
337. Filtrasorb
338. Filtrasorb 200
339. Filtrasorb 400
340. Flamruss
341. Formocarbine
342. Fortafil 5y
343. Ft-0621888
344. Ft-0623469
345. Fullerene Soot
346. Furnace Black
347. Furnal
348. Furnex
349. Furnex N 765
350. Gas Black
351. Gas-furnace Black
352. Gastex
353. Gk 2
354. Gk 3
355. Gp 60
356. Gp 60s
357. Gp 63
358. Grafoil
359. Grafoil Gta
360. Graphene
361. Graphite
362. Graphite (all Forms Except Graphite Fibers)
363. Graphite (natural), Dust
364. Graphite (synthetic)
365. Graphite, Natural
366. Graphite, Synthetic
367. Graphitic Acid
368. Graphnol N 3m
369. Grosafe
370. Gs 2
371. Gy 70
372. H 451
373. Hitco Hmg 50
374. Hsdb 2017
375. Hsdb 5037
376. Hsdb 7713
377. Hsdb 953
378. Huber
379. Humenegro
380. Hydrodarco
381. I14-114468
382. I14-45191
383. I14-52609
384. Ig 11
385. Impingement Black
386. Impingement Carbons
387. Irgalite 1104
388. Jado
389. K 257
390. Ketjenblack Ec
391. Kohlenstoff
392. Korobon
393. Kosmink
394. Kosmobil
395. Kosmolak
396. Kosmos
397. Kosmotherm
398. Kosmovar
399. Lamp Black
400. Lampblack
401. Ls-51900
402. Ls-59580
403. Ma 100 (carbon)
404. Magecol
405. Medicinal Carbon
406. Metanex
407. Mg 1
408. Micronex
409. Miike 20
410. Mineral Carbon
411. Modulex
412. Mogul
413. Mogul L
414. Molacco
415. Monarch 1300
416. Monarch 700
417. Mpg 6
418. Neo Spectra Beads Ag
419. Neo-spectra Ii
420. Neo-spectra Mark Ii
421. Neotex
422. Niteron 55
423. Norit
424. Norit A, U.s.p.
425. Nuchar
426. Oil-furnace Black
427. Ou-b
428. P 33 (carbon Black)
429. P1250
430. P68
431. Papyex
432. Peach Black
433. Pelikan C 11/1431a
434. Pelletex
435. Permablak 663
436. Pg 50
437. Philblack
438. Philblack N 550
439. Philblack N 765
440. Philblack O
441. Pigment Black 6
442. Pigment Black 7
443. Plumbago
444. Plumbago (graphite)
445. Printex
446. Printex 60
447. Pyro-carb 406
448. Raven
449. Raven 30
450. Raven 420
451. Raven 500
452. Raven 8000
453. Rebonex
454. Regal
455. Regal 300
456. Regal 330
457. Regal 400r
458. Regal 600
459. Regal 99
460. Regal Srf
461. Regent
462. Rl04457
463. Rocol X 7119
464. Royal Spectra
465. Rtr-024045
466. S 1
467. S 1 (graphite)
468. Schungite
469. Sevacarb
470. Seval
471. Shawinigan Acetylene Black
472. Shell Carbon
473. Shungite
474. Silver Graphite
475. Single Wall Carbon Nanotube
476. Skg
477. Skln 1
478. Skt
479. Skt (adsorbent)
480. Special Black 1v & V
481. Special Schwarz
482. Spheron
483. Spheron 6
484. Statex
485. Statex N 550
486. Sterling Mt
487. Sterling N 765
488. Sterling Ns
489. Sterling So 1
490. Stove Black
491. Su 2000
492. Suchar 681
493. Super-carbovar
494. Super-spectra
495. Superba
496. Supersorbon Iv
497. Supersorbon S 1
498. Swcnt
499. Swedish Black Lead
500. Swine Fly Ash
501. Swnt
502. Therma-atomic Black
503. Thermal Acetylene Black
504. Thermal Black
505. Thermatomic
506. Thermax
507. Thermblack
508. Tinolite
509. Tm 30
510. Toka Black 4500
511. Toka Black 5500
512. Toka Black 8500
513. Tr-024045
514. U 02
515. Ucar 38
516. Ultracarbon
517. Un1362
518. Unii-2p3vwu3h10
519. Unii-4qqn74lh4o
520. Unii-4xyu5u00c4
521. Vitreous Carbon
522. Vvp 66-95
523. W8209
524. Watercarb
525. Whetlerite
526. Witcarb 940
527. Xe 340
528. Xf 4175l
529. Graphite Powder
530. Mfcd00133992
531. Carbon Nanotubes
532. Mfcd00144065
533. Mfcd00146977
534. Mfcd00211867
535. Single-walled Carbon Nanotubes (swnts)
536. Multi-walled Carbon Nanotubes (mwnts), 95+%
537. Graphite Rod, 6.15mm (0.242in) Dia X 152mm (6in) Long
538. Graphite Rod, 6.15mm (0.242in) Dia X 305mm (12in) Long
539. Acetylene Carbon
540. Coconut Charcoal
541. Carbon Rods, 5n
542. 1034343-98-0
543. Activated Carbon, Pellets 3mm
544. Carbon, Activated, -4+8 Mesh
545. Carbon, Activated, 2mm & Down
546. Diamond Synthesized, 95% Nano
547. Carbon Conductive Cement Adhesive
548. Carbon Black, Super P Conductive
549. Carbon Slug, Activated, 6-8 Mesh
550. Carbon, Activated, -20+40 Mesh
551. Carbon Powder, 99.999%, 5n
552. Graphite Flake, Natural, -10 Mesh
553. Graphite Ink For Tantalum Capacitors
554. Diamond Powder (gray), 97+% Nano
555. Diamond Powder (gray), 98+% Nano
556. Graphite Flake, Median 7-10 Micron
557. Mfcd06411993
558. Mfcd07370731
559. Graphite Flake, Natural, -325 Mesh
560. Graphite Foil, 1mm (0.04in) Thick
561. Diamond Powder, Synthetic, <1 Mircron
562. Graphite Rod, 5.0mm (0.20in) Dia
563. Carbon Felt, 1.27cm (0.5in) Thick
564. Carbon Felt, 2.54cm (1.0in) Thick
565. Carbon, Darco™ G-60, Activated
566. Double-walled Carbon Nanotubes (dwnts)
567. Graphite Plate, 2.5cm (1.0in) Thick
568. Carbon Black, Acetylene, 50% Compressed
569. Carbon Felt, 6.35mm (0.25in) Thick
570. Diamond Powder (black), 52-65% Nano
571. Graphite Foil, 0.5mm (0.02in) Thick
572. Graphite Rod, 10.0mm (0.40in) Dia
573. Graphite Plate, 1.27cm (0.5in) Thick
574. Acetylene Carbon Black (100% Compressed)
575. Carbon Felt, 3.18mm (0.125in) Thick
576. Diamond Powder, Synthetic, 40-60 Micron
577. Graphite Foil, 0.4mm (0.015in) Thick
578. Graphite Powders, 99.9% (metals Basis)
579. Graphite Foil, 0.13mm (0.005in) Thick
580. Graphite Foil, 0.254mm (0.01in) Thick
581. Graphite Powder, Nickel Coated, -100 Mesh
582. Graphite Powder, Synthetic, -20+100 Mesh
583. Carbon Nanotubes, Single-walled/double-walled
584. G0500
585. G0501
586. G0502
587. N0968
588. N0969
589. Single-walled Carbon Nanotubes (swnts-cooh)
590. Carbon Nanotubes, Multi-walled, Core Material
591. Graphite Powder, Synthetic, Aps 7-11 Micron
592. Graphite, Colloidal, Lubricant, Aerosol Spray
593. Multi-walled Carbon Nanotubes (mwnts), 95%
594. Glassy Carbon Rod, 3mm (0.1in) Dia, Type 1
595. Glassy Carbon Rod, 3mm (0.1in) Dia, Type 2
596. Glassy Carbon Rod, 5mm (0.2in) Dia, Type 1
597. Glassy Carbon Rod, 5mm (0.2in) Dia, Type 2
598. Multi-walled Carbon Nanotubes (mwnts), 90+%
599. Glassy Carbon Rod, 1mm (0.04in) Dia, Type 1
600. Glassy Carbon Rod, 1mm (0.04in) Dia, Type 2
601. Glassy Carbon Rod, 2mm (0.08in) Dia, Type 1
602. Glassy Carbon Rod, 2mm (0.08in) Dia, Type 2
603. Glassy Carbon Rod, 4mm (0.16in) Dia, Type 1
604. Glassy Carbon Rod, 4mm (0.16in) Dia, Type 2
605. Glassy Carbon Rod, 6mm (0.24in) Dia, Type 1
606. Glassy Carbon Rod, 6mm (0.24in) Dia, Type 2
607. Glassy Carbon Rod, 7mm (0.28in) Dia, Type 1
608. Glassy Carbon Rod, 7mm (0.28in) Dia, Type 2
609. Glassy Carbon Plate, 3mm (0.1in) Thick, Type 1
610. Glassy Carbon Plate, 3mm (0.1in) Thick, Type 2
611. Graphite Powder, Natural, High Purity, -200 Mesh
612. Carbon Nanotubes, Multi-walled, Ground Core Material
613. Glassy Carbon Plate, 1mm (0.04in) Thick, Type 1
614. Glassy Carbon Plate, 1mm (0.04in) Thick, Type 2
615. Glassy Carbon Plate, 2mm (0.08in) Thick, Type 1
616. Glassy Carbon Plate, 2mm (0.08in) Thick, Type 2
617. Glassy Carbon Plate, 4mm (0.16in) Thick, Type 1
618. Glassy Carbon Plate, 4mm (0.16in) Thick, Type 2
619. Glassy Carbon Splinter Powder, 20-50 Micron, Type 1
620. Graphite Powder, Natural, Universal Grade, -200 Mesh
621. Nanodiamond (particle Size : <10nm) (amine-modified)
622. Carbon Yarn, Woven From 0.076mm (0.003in) Dia Fibers
623. Glassy Carbon Spherical Powder, 0.4-12 Micron, Type 1
624. Glassy Carbon Spherical Powder, 0.4-12 Micron, Type 2
625. Glassy Carbon Spherical Powder, 10-20 Micron, Type 1
626. Glassy Carbon Spherical Powder, 10-20 Micron, Type 2
627. Glassy Carbon Splinter Powder, 0.4-12 Micron, Type 1
628. Glassy Carbon Splinter Powder, 0.4-12 Micron, Type 2
629. Glassy Carbon Splinter Powder, 80-200 Micron, Type 1
630. Glassy Carbon Splinter Powder, 80-200 Micron, Type 2
631. Graphite Powder, Natural, Briquetting Grade, -100 Mesh
632. Graphite Powder, Natural, Briquetting Grade, -200 Mesh
633. Graphite Powder, Synthetic, Conducting Grade, -200 Mesh
634. Graphite Powder, Synthetic, Conducting Grade, -325 Mesh
635. Graphite Rod, 3.8cm (1.5in) Dia X 61cm (24in) Long
636. Carbon Nanotubes, Multi-walled, As Produced Cathode Deposit
637. Fullerene, Buckytube/nanotube, Single Walled, > 60% Swnt
638. Fullerene, Buckytube/nanotube, Single Walled, 20-35% Swnt
639. Funct. Multi-walled Carbon Nanotubes (mwnts-cooh), 95+%
640. Glassy Carbon Spherical Powder, 200-400 Micron, Type 1
641. Glassy Carbon Spherical Powder, 200-400 Micron, Type 2
642. Glassy Carbon Spherical Powder, 400-630 Micron, Type 2
643. Glassy Carbon Spherical Powder, 630-1000 Micron, Type 1
644. Glassy Carbon Spherical Powder, 630-1000 Micron, Type 2
645. Graphite Plate, Resin Impregnated, 6.35mm (0.25in) Thick
646. Graphite Rod, 1.27cm (0.5in) Dia X 61cm (24in) Long
647. Graphite Rod, 2.54cm (1.0in) Dia X 61cm (24in) Long
648. Graphite Rod, 6.3mm (0.25in) Dia. X 61cm (24in) Long
649. Nanodiamond (particle Size : <10nm) (carboxyl-modified)
650. Carbon, Activated, Norit Row 0.8mm Pellets, Steam Activated
651. Graphite Powder, Natural, Microcrystal Grade, Aps 2-15 Micron
652. Graphite Rod, 3.05mm (0.12in) Dia X 305mm (12in) Long
653. Graphite Rod, 6.15mm (0.242in) Dia X 102mm (4in) Long
654. Multi-walled Carbon Nanotubes (mwnts), 95%, Od 40-60 Nm
655. Multi-walled Carbon Nanotubes (mwnts), 95+%, Od 50-80 Nm
656. Carbon Nanotube Multi-walled 10-20nm(diam.), 5-15microm(length)
657. Carbon Nanotube Multi-walled 10-30nm(diam.), 5-15microm(length)
658. Carbon Nanotube Multi-walled 20-40nm(diam.), 1-2microm(length)
659. Carbon Nanotube Multi-walled 20-40nm(diam.), 5-15microm(length)
660. Carbon Nanotube Multi-walled 40-60nm(diam.), 1-2microm(length)
661. Carbon Nanotube Multi-walled 40-60nm(diam.), 5-15microm(length)
662. Carbon Nanotube Multi-walled 60-100nm(diam.), >5microm(length)
663. Carbon Powder, Activated, Norit Gsx, Steam Activated, Acid Washed
664. Fullerene, Nanotube, Multi-walled, 20 Nm Od, 5-20 Micron Long
665. Graphite, Fusion Crucible, Drillpoint, Unpurified, Volume 7.5cc
666. Graphite, Fusion Crucible, Drillpoint, Unpurified, Volume 7.88cc
667. Carbon Nanotube Aligned Multi-walled 10-20nm(diam.), 5-15microm(length)
668. Carbon Sputtering Target, 50.8mm (2.0in) Dia X 3.18mm (0.125in) Thick
669. Carbon Sputtering Target, 76.2mm (3.0in) Dia X 3.18mm (0.125in) Thick
670. Graphite Electrode, Counter-pointed Tip, 3.06mm Dia, 38.10 Mm Long
671. Graphite Electrode, Counter-spherical Tip, 6.15mm Dia, 38.10 Mm Long
672. Graphite Plate, Pyrolytic, 1.27x9.98x9.98mm (0.05x0.393x.393in)
673. Graphite Powder, Microcrystalline, -300 Mesh, 75-82% C, 18-25% Ash
674. Graphite Rod, Pyrolytic Coated, 2mm (0.08in) Dia X 152mm (6in) Long
675. Metals Scavenging Agent, Phosphotungstic Acid Modified Activated Carbon
676. Multi-walled Carbon Nanotubes (mwnts), 95%, Outside Diameter 10-20 Nm
677. Multi-walled Carbon Nanotubes (mwnts), 95%, Outside Diameter 20-30 Nm
678. Carbon Nanotube Array, Multi-walled, On Quartz (diameter= 100nm, Length=30 Microns)
679. Carbon Nanotubes, Multi-walled (diameter= 140nm, Length= 7microns)(>90%nanotubes)
680. Fullerene, Nanotube, Multi-walled, As-produced Cathode Deposits, Core And Shell
681. Total Organic Carbon (toc), Standard Solution, Specpure(r), 1000 Microgram/ml
682. Carbon Nanotube Single-walled (>85%) Below 3nm(average Diam.), Over 5microm(average Length)
683. Carbon Nanotubes, Multi-walled, Arc-produced (diameter = 2-50nm, Length = >2 Microns) (55-65wt% Nanotubes)
684. Graphite Electrode, Crater-drillpoint/undercut, 4.57mm Dia, 38.10mm Length, Volume 0.040cc
685. Graphite Fusion Crucible Lid For Stock Number 40794, 2.54cm (1.0in) Dia, 6.35mm (0.25in) Thick
686. Graphite Plate, Highly Oriented Pyrolytic Graphite (hopg), 10x10x(1.6min)mm (0.394x0.394x0.079in), 0.4 +0.1 O Mosaic Angle
687. Graphite Plate, Highly Oriented Pyrolytic Graphite (hopg), 10x10x(1.6min)mm (0.394x0.394x0.079in), 0.8 +0.2 O Mosaic Angle
688. Graphite Plate, Highly Oriented Pyrolytic Graphite (hopg), 10x10x1mm (0.394x0.394x0.039in), 0.4 +0.1 O Mosaic Angle
689. Graphite Plate, Highly Oriented Pyrolytic Graphite (hopg), 10x10x1mm (0.394x0.394x0.039in), 0.8 +0.2 O Mosaic Angle
690. Oh Functionalized Single-walled Carbon Nanotubes (swnts-oh), Purity (excluding -oh): 90% Cnts, 60% Swnts, Content Of -oh: 3.76-4.16 Wt%
691. Oh Functionalized Single-walled Carbon Nanotubes (swnts-oh), Purity (excluding -oh): 95% Cnts, 90% Swnts, Content Of -oh: 3.76-4.16 Wt%
| Molecular Weight | 12.011 g/mol |
|---|---|
| Molecular Formula | C |
| XLogP3 | 0.6 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 0 |
| Rotatable Bond Count | 0 |
| Exact Mass | 12 g/mol |
| Monoisotopic Mass | 12 g/mol |
| Topological Polar Surface Area | 0 Ų |
| Heavy Atom Count | 1 |
| Formal Charge | 0 |
| Complexity | 0 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Antidotes
National Library of Medicine's Medical Subject Headings online file (MeSH, 1999)
Activated charcoal has been used in the management of erythropoietic porphyria (to interrupt the enterohepatic recycling of protoporphyrin and lower plasma porphyrin concentrations) and for symptomatic relief of pruritis in patients with renal failure.
American Society of Health System Pharmacists. AHFS Drug Information 2008. Bethesda, Maryland 2008, p. 2966
Activated charcoal also has been used topically in wound or ulcer dressings to decrease odor and promote healing.102
American Society of Health System Pharmacists. AHFS Drug Information 2008. Bethesda, Maryland 2008, p. 2966
Activated charcoal has been used to adsorb intestinal gases in the treatment of flatulence, intestinal distension, and dyspepsia; however, the US Food and Drug Administration (FDA) has classified activated charcoal as lacking substantial evidence of efficacy as an antiflatulent or digestive aid. Activated charcoal has been used alone or in combination with kaolin in the management of diarrhea but its value has not been established.
American Society of Health System Pharmacists. AHFS Drug Information 2008. Bethesda, Maryland 2008, p. 2966
For more Therapeutic Uses (Complete) data for ACTIVATED CHARCOAL (28 total), please visit the HSDB record page.
/EXPL THER/ Single-walled carbon nanotubes (SWCNTs) were covalently linked to epidermal growth factor (EGF) proteins through an esterification process that was found to be responsible for the docking of SWCNTs on the human pancreatic cancer cells (PANC-1) surface, thus providing a mechanism for the enhanced delivery and internalization of the nanotubes. Micro Raman spectroscopy and enzyme-linked immunosorbent assay were used to evaluate the delivery process and kinetics of the SWCNTs. In vitro studies indicated that the delivery kinetics of SWCNT-EGF conjugates, at a concentration of 85 ug/mL, to the PANC-1 cell surfaces was significant in the first 30 min of incubation, but reached a plateau with time in accordance with the establishment of equilibrium between the association and the dissociation of EGF with the cell receptors. SWCNT-EGF conjugates could act as strong thermal ablation agents and could induce higher percentages of cellular death compared with the nontargeted SWCNTs alone. /Molecular carrier system/
PMID:22147491 Karmakar A et al; J Appl Toxicol 32 (5): 365-75 (2012)
/EXPL THER/ Single-walled carbon nanotubes are currently under evaluation in biomedical applications, including in vivo delivery of drugs, proteins, peptides and nucleic acids (for gene transfer or gene silencing), in vivo tumor imaging and tumor targeting of single-walled carbon nanotubes as an anti-neoplastic treatment. /Single-walled carbon nanotubes/
Schipper ML et al; Nature Nanotechnology 3, 216 - 221 (2008)
/EXPL THER/ The development of nanomaterials for biomedical and biotechnological applications is an area of research that holds great promise and intense interest, and ... carbon nanotubes (CNTs) are attracting an increasing level of attention. One of the key advantages that CNTs offer is the possibility of effectively crossing biological barriers, which would allow their use in the delivery of therapeutically active molecules. ... Laboratories have been investigating the use of CNTs ... as nanovectors for therapeutic agent delivery. The interaction between cells and CNTs is a critical issue that will determine any future biological application of such structures. ... Various types of functionalized carbon nanotubes (f-CNTs) exhibit a capacity to be taken up by a wide range of cells and can intracellularly traffic through different cellular barriers. /Molecular carrier system/
Kostarelos K et al; Nature Nanotechnology 2, 108 - 113 (2006)
/EXPL THER/ An array of chemiresistive random network of single-walled carbon nanotubes coated with nonpolymeric organic materials shows a high potential for diagnosis of lung cancer via breath samples. The sensors array shows excellent discrimination between the volatile organic compounds (VOCs) found in the breath of patients with lung cancer, relative to healthy controls, especially if the sensors array is preceded with either water extractor and/or preconcentrator of VOCs. The pattern compositions of the healthy and cancerous states were determined by gas-chromatography linked with mass-spectroscopy (GC-MS) analysis of real exhaled breath. /Single-walled carbon nanotubes/
PMID:18839997 Peng G et al; Nano Lett 8 (11): 3631-5 (2008)
For more Therapeutic Uses (Complete) data for CARBON NANOTUBES (7 total), please visit the HSDB record page.
Charcoal bezoars are a rare complication of activated charcoal administration. They have been associated with treatments for intoxication with carbamazepine, amitriptyline, theophylline, benzodiazepines and barbiturates. The parasympatholytic effects of the drugs can precipitate or contribute to paralytic ileus, allowing charcoal to accumulate (potentially with remnants of undigested tablets) and form bezoars. Additional factors that influence bowel obstruction secondary to charcoal administration include the dose and timing of activated charcoal therapy, patient age and comorbidities, and previous intra-abdominal surgery. Gastrointestinal complications should be considered whenever activated charcoal is administered. Prompt recognition and treatment at the first sign of ileus or obstruction may prevent bowel necrosis and subsequent perforation/peritonitis. Charcoal-stained vomiting, abdominal distension and ongoing pain should raise the suspicion of mechanical obstruction. ... Gastrografin follow-through /was advocated/ as both a diagnostic and potentially therapeutic tool in incomplete obstruction. However, complete obstruction may signal the need for early laparotomy.
PMID:16296970 Chan JCY; Med J Australia 183 (10): 537 (2005)
/VET/ ... Six healthy adult dogs were administered 4 g/kg activated charcoal (AC) in a commercially available suspension that contained propylene glycol and glycerol as vehicles. Blood samples were taken before and 1, 4, 6, 8, 12, and 24 hours after the administration of the test suspension /and/ ... analyzed for osmolality, blood gases, and concentrations of lactate, sodium, potassium, serum urea nitrogen, and glucose. ... Three of the 6 dogs vomited between 1 and 3 hours after the administration of the test suspension, and 4 of 6 dogs were lethargic. All dogs drank frequently after AC administration. Commercial AC suspension administered at a clinically relevant dose /significantly increased/ serum osmolality, osmolal gap, and lactate concentration in dogs. These laboratory measures, ...clinical signs ... and increased frequency of drinking might complicate the diagnosis or monitoring of some intoxications (such as ethylene glycol) in dogs that have previously received AC suspension containing propylene glycol, glycerol, or both as vehicles.
PMID:16231712 Burkitt JM et al; J Vet Intern Med 19 (5): 683-6 (2005)
Although activated charcoal is widely used for the treatment of self-poisoning, its effectiveness is unknown. An important consideration is patient compliance since poor compliance will limit effectiveness. ... 1,103 patients randomized to single or multiple (six doses q4h) 50 g doses of superactivated charcoal were prospectively observed. Charcoal was given by study doctors who recorded the amount ingested and the amount of persuasion required for the patients to drink the charcoal. ... 559 patients were randomized to receive one dose and 544 to receive six doses. Data was available for 1,071 (97%) patients. Eighty-eight were unable to complete their course; 98 required a NG tube, leaving 885 patients that received the first dose by mouth. The mean estimated amount of the prescribed dose of charcoal taken orally as a single or first dose was 83% (95% C.I. 82-84%). For patients receiving multiple doses, this amount fell over the next five doses to 66% (63-69%). While only 3.2% of patients refused the first dose, 12.3% refused the sixth. Relatively less persuasion was required for patients ingesting the first or single dose; 38% of patients required intense persuasion by the sixth dose.
PMID:17364629 Full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950600 Mohamed F et al; Clin Toxicol (Phila) 45 (2): 132-5 (2007)
... The incidence of aspiration pneumonia in intubated overdose patients who then received activated charcoal (AC) /was estimated by /... a retrospective review from January 1994 to April 1997 of intubated patients who then received AC. Patients were transferred to, or primarily treated at, an 843-bed tertiary medical center with an annual emergency department volume of 100,000 patients. Objective evidence of infiltrate on chest radiograph during initial 48 hr of hospitalization was used to determine the incidence of aspiration pneumonia. Patients with known preexisting pneumonia or with administration of AC before intubation were excluded. There were 64 patients identified. Fourteen were excluded for clinical aspiration before intubation, receiving activated charcoal before intubation, or abnormal immediate post-intubation chest radiographs. The remaining 50 patients, ages 1-64 years, 33% male, overdosing on a large variety of substances, required acute intubation and then received AC. Only two patients of these 50 (4%) with initial negative radiographs developed a new infiltrate after intubation and AC. Administration of AC to intubated overdose patients is associated with a low incidence of aspiration pneumonia.
PMID:10195487 Moll J et al; J Emerg Med 17 (2): 279-83 (1999)
For more Drug Warnings (Complete) data for ACTIVATED CHARCOAL (16 total), please visit the HSDB record page.
Uptake and retention of carbon black particles in lung macrophages have been observed following inhalation ... as well as following injection into the cerebral ventricles of rats ... or into the bladder wall of rats. ... Carbon black particles perfused into the abdominal aorta of rabbits were observed in the endothelial cells of the vessel.
IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V33 70 (1984)
Particles were found in phagocytic cells in the proximal convoluted tubules and glomeruli of the kidneys in mice, together with amyloidosis and renal fibrosis. It was later reported that carbon black particles also accumulated in the lungs of exposed monkeys (total duration of exposure, 5784 hr) ...
IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V33 69 (1984)
Mice (for their lifespan), guinea pigs, and monkeys (up to 13,000 total hr) were exposed to 1.6 mg/cu m of various types of furnace blacks for 7 hr/day, 5 days/wk. ... Carbon black was found scattered in lung tissue, both free-lying and inside macrophages (scavenger cells). In mice, the black was diffuse and finely distributed, while monkeys progressively developed diffusely distributed areas of nodularity where the black was concentrated. ... Carbon black was observed to infiltrate the pulmonary lymph nodes, and was also present in the liver, spleen, and kidneys of exposed animals.
USEPA; Chemical Hazard Information Profile: Carbon Black p.67 (1978) EPA-560/11-80-011
The effect of continuous exposure to inert carbonaceous particles on the pulmonary clearance of inhaled diesel tracer particles was studied in male Fischer 344 rats. Submicron carbon black particles with a mass median aerodynamic diameter of 0.22 um and having a size distribution similar to those particles from a GM 5.7 liter diesel engine were successfully generated and admin to test animals at a nominal concn of 6 mg/cu m for 20 hr/day, 7 day/wk, for periods lasting 1 to 11 wk. Immediately after the carbon black exposure, test animals were admin (14)C tagged diesel particles for 45 min in a nose only chamber. The pulmonary retention of inhaled radioactive tracer particles was determined at preselected time intervals. Based upon the data collected up to six months post exposure, prolonged exposure to carbon black particles exhibits the same inhibitory effect on pulmonary clearance as prolonged exposure to diesel exhaust with a comparable particulate dose. This observation, coupled with the observation that continuous exposure to nitrogen oxide at 2 ppm produced no significant incr on the pulmonary retention of radioactive diesel test particles, indicates that the accumulation of inert carbonaceous material is the predominant cause of impaired lung clearance.
Lee PS et al; Fed Proc 43 (3): (1984)
For more Absorption, Distribution and Excretion (Complete) data for CARBON BLACK (10 total), please visit the HSDB record page.
Activated charcoal is neither absorbed in the GI tract nor metabolized, and it is excreted in feces.
American Society of Health System Pharmacists. AHFS Drug Information 2008. Bethesda, Maryland 2008, p. 2968
EXPTL INTRAVENOUS INJECTION OF PURE CARBON SUSPENSIONS IN RABBITS PRODUCES NO OCULAR INFLAMMATION, ALTHOUGH CARBON PARTICLES ARE DEPOSITED WITHIN THE BLOOD VESSELS.
Grant, W.M. Toxicology of the Eye. 3rd ed. Springfield, IL: Charles C. Thomas Publisher, 1986., p. 178
Individualized, chemically pristine single-walled carbon nanotubes have been intravenously administered to rabbits and monitored through their characteristic near-infrared fluorescence. Spectra indicated that blood proteins displaced the nanotube coating of synthetic surfactant molecules within seconds. The nanotube concentration in the blood serum decreased exponentially with a half-life of 1.0 +/- 0.1 hr. No adverse effects from low-level nanotube exposure could be detected from behavior or pathological examination. At 24 hr after iv administration, significant concentrations of nanotubes were found only in the liver. These results demonstrate that debundled single-walled carbon nanotubes are high-contrast near-infrared fluorophores that can be sensitively and selectively tracked in mammalian tissues using optical methods. In addition, the absence of acute toxicity and promising circulation persistence suggest the potential of carbon nanotubes in future pharmaceutical applications. /Single-walled carbon nanotubes/
PMID:17135351 Full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1665645 Cherukuri P et al; Proc Natl Acad Sci U S A 103 (50): 18882-6 (2006)
Single-walled carbon nanotubes (SWNTs) exhibit unique size, shape and physical properties that make them promising candidates for biological applications. Here, ... the biodistribution of radio-labelled SWNTs in mice /is investigated/ by in vivo positron emission tomography (PET), ex vivo biodistribution and Raman spectroscopy. It is found that SWNTs that are functionalized with phospholipids bearing polyethylene-glycol (PEG) are surprisingly stable in vivo. The effect of PEG chain length on the biodistribution and circulation of the SWNTs is studied. Effectively PEGylated SWNTs exhibit relatively long blood circulation times and low uptake by the reticuloendothelial system (RES). Efficient targeting of integrin positive tumor in mice is achieved with SWNTs coated with PEG chains linked to an arginine-glycine-aspartic acid (RGD) peptide. A high tumor accumulation is attributed to the multivalent effect of the SWNTs... /Functionalized single-walled carbon nanotubes/
Liu Z et al; Nature Nanotechnology 2, 47 - 52 (2006)
Carbon nanotubes are promising new materials for molecular delivery in biological systems. The long-term fate of nanotubes intravenously injected into animals in vivo is currently unknown, an issue critical to potential clinical applications of these materials. Here, using the intrinsic Raman spectroscopic signatures of single-walled carbon nanotubes (SWNTs), ... the blood circulation of intravenously injected SWNTs and detect SWNTs /was measured/ in various organs and tissues of mice ex vivo over a period of three months. Functionalization of SWNTs by branched polyethylene-glycol (PEG) chains was developed, enabling thus far the longest SWNT blood circulation up to 1 day, relatively low uptake in the reticuloendothelial system (RES), and near-complete clearance from the main organs in approximately 2 months. Raman spectroscopy detected SWNT in the intestine, feces, kidney, and bladder of mice, suggesting excretion and clearance of SWNTs from mice via the biliary and renal pathways. No toxic side effect of SWNTs to mice was observed in necropsy, histology, and blood chemistry measurements. ... /Functionalized single-walled carbon nanotubes/
PMID:18230737 Full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234157 Liu Z et al; Proc Natl Acad Sci U S A.105 (5): 1410-5 (2008)
Single walled carbon nanotubes (SWCNT) have a small size and unique physicalchemical properties which suggest that novel particles may translocate to systemic organs after deposition in the lungs. In this study, gold particles (10 nm) were used to label a highly dispersed preparation of SWCNT with a mean geometric diameter of 1.1 microns. The gold labeled SWCNT were delivered to the lungs by pharyngeal aspiration to C57BL/6 mice. Neutron activation analysis (NAA) of lung, blood and other organs was carried out at various times after aspiration to determine if the gold labeled SWCNT translocated out of the lungs. Six mice per group were studied at 1 hour, 1 day and 3 days after exposure to a single dose of 50 ug of gold labeled SWCNT. A separate group was given gold particles without SWCNT. A phosphate buffered saline (PBS) aspiration group served as the negative control. At sacrifice the lungs, heart, brain, liver, kidneys and a blood sample were taken for analysis of gold content by NAA. Gold content of the PBS aspiration group was negligible. In the gold labeled SWCNT group lung gold content at 1 day was 65 percent of that at 1 hour and not significantly different from the content at 3 days. The heart, brain, liver, kidney and blood samples from the gold labeled SWCNT groups contained less than 1 part in 200 of the total dose and were not statistically different from the PBS aspiration group at 1 hour, 1 day and 3 days. The results indicate that SWCNT do not readily translocate from the lungs. /Single-walled carbon nanotubes/
Mercer RR et al; Toxicologist 102 (1): 286, abstract 1399 (2008)
For more Absorption, Distribution and Excretion (Complete) data for CARBON NANOTUBES (6 total), please visit the HSDB record page.
Small quantities of carbon suspensions in the form of graphite or India ink injected into the anterior chamber of /the eyes of/ rabbits is mostly taken up by the leukocytes and by the corneal endothelium, producing essentially no signs of inflammation.
Grant, W.M. Toxicology of the Eye. 3rd ed. Springfield, IL: Charles C. Thomas Publisher, 1986., p. 178
Activated charcoal is neither absorbed in the GI tract nor metabolized, and it is excreted in feces.
American Society of Health System Pharmacists. AHFS Drug Information 2008. Bethesda, Maryland 2008, p. 2968
Individualized, chemically pristine single-walled carbon nanotubes have been intravenously administered to rabbits and monitored through their characteristic near-infrared fluorescence. ... The nanotube concentration in the blood serum decreased exponentially with a half-life of 1.0 +/- 0.1 hr. /Single-walled carbon nanotubes/
PMID:17135351 Full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1665645 Cherukuri P et al; Proc Natl Acad Sci U S A 103 (50): 18882-6 (2006)
Macrophages were treated with carbon black and carbon black adsorbate complexes to determine whether the presence, identity and coverage of the adsorbate altered the phagocytic ingestion of the carbon black particles. This study was performed to determine the effect of such treatment on the capacity of the macrophages to phagocytize a secondary particle challenge via its Fc membrane receptor. Rat alveolar macrophages were incubated in vitro with two carbon blacks that had 15 fold differences in specific surface areas (ASTM-N339 less than Black-Pearls-2000) sorbed with 0.5 and 1.0 monolayer coverages of a polar and semi polar adsorbate; acrolein and benzofuran. One half monolayer coverages of N339 with either adsorbate significantly suppressed the phagocytosis of the carbon black, whereas one monolayer coverage did not. Neither adsorbate at either coverages affected the phagocytosis of Black-Pearls-2000. It was concluded that these results indicate that the surface properties of the particles, the chemical properties of chemical pollutants, and the interactions between particles and pollutants can play a major role in defining the biological effects of particles that are carried to the distal lung.
PMID:2088744 Full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567780 Jakab GJ et al; Environmental Health Perspectives 89: 169-74 (1990)
The desorption of adsorbed molecules from amorphous carbon black was investigated. Five oil furnace carbon blacks consisting of pelletized agglomerates of 0.20 to 0.24 nanometer aciniform particles and 13 adsorbates were used. The adsorbates consisted of organic compounds containing functional groups characteristic of organic molecules formed on particles generated by combustion of organic material. The carbon blacks were incorporated into liquid chromatographic columns. n-Hexane, dichloromethane, tetrahydrofuran, methanol, and water were used as mobile phases. Ten microliter sample aliquots were injected into the chromatographs. The data showed that the adsorbates displaced the mobile phase molecules from the surface. The extent of desorption increased with increasing solubility of the adsorbate in the mobile phase. Desorption also depended on the heat of desorption. With the exception of basic adsorbates adsorbed on the least polar carbon black, N765, most of the compounds were adsorbed irreversibly when the mobile phase was water. The adsorption isotherms showed that desorption depended on the extent of surface coverage and increased as the extent of coverage approached one monolayer. It was concluded that adsorbed molecules are desorbed from particulate surfaces to different extents, the amount desorbed depending on the polarity of the physiological fluid that interacts with the surface. Desorption also depends on the extent of adsorbent surface covered.
Risby TH et al; Environ Health Perspectives 77: 141-9 (1988)
Exposure to ambient ultrafine particles induces airway inflammatory reactions and tissue remodeling. In this experiment, to determine whether ultrafine carbon black (ufCB) affects proliferation of airway epithelium and, if so, what the mechanism of action is, ... human primary bronchial epithelial cell cultures /were studied/. Incubation of cells in the serum-free medium with ufCB increased incorporations of [(3)H]thymidine and [(3)H]leucine into cells in a time- and dose-dependent manner. This effect was attenuated by Cu- and Zn-containing superoxide dismutase (Cu/Zn SOD) and apocynin, an inhibitor of NADPH oxidase, and completely inhibited by pretreatment with the epidermal growth factor receptor (EGF-R) tyrosine kinase inhibitors AG-1478 and BIBX-1382, and the mitogen-activated protein kinase kinase inhibitor PD-98059. Transfection of a dominant-negative mutant of H-Ras likewise abolished the effect ufCB. Stimulation with ufCB also induced processing of membrane-anchored proheparin-binding (HB)-EGF, release of soluble HB-EGF into the medium, association of phosphorylated EGF-R and Shc with glutathione-S-transferase-Grb2 fusion protein, and phosphorylation of extracellular signal-regulated kinase (ERK). Pretreatment with AG-1478, [Glu(52)]Diphtheria toxin, a specific inhibitor of HB-EGF, neutralizing HB-EGF antibody, Cu/Zn SOD, and apocynin each inhibited ufCB-induced ERK activation. These results suggest that ufCB causes oxidative stress-mediated proliferation of airway epithelium, involving processing of HB-EGF and the concomitant activation of EGF-R and ERK cascade.
PMID:15298855 Tamaoki J et al; Am J Physiol 287 (6): 1127-33 (2004)
... Ultrafine carbon black (ufCB) does not have its effects via transition metal-mediated mechanisms. However, ufCB and other ultrafines generate free radicals at their surface as measured by a number of chemical assays and are able to cause oxidative stress to cells and this is likely to be a factor in their ability to cause inflammation. Changes in calcium resulting from oxidative stress within cells may be an additional factor leading to transcription of pro-inflammatory genes...
PMID:12762574 MacNee W, Donaldson K; Eur Resp J Suppl 40: 47-51 (2003)
Activated charcoal avidly adsorbs drugs and chemicals on the surfaces of the charcoal particles, thereby preventing absorption and toxicity. ... The effectiveness of charcoal is dependent on the time since the ingestion and on the dose of charcoal; one should attempt to achieve a charcoal:drug ratio of at least 10:1.
Hardman, J.G., L.E. Limbird, P.B., A.G. Gilman. Goodman and Gilman's The Pharmacological Basis of Therapeutics. 11th ed. New York, NY: McGraw-Hill, 2006., p. 1748
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A Carbon supplier is an individual or a company that provides Carbon active pharmaceutical ingredient (API) or Carbon finished formulations upon request. The Carbon suppliers may include Carbon API manufacturers, exporters, distributors and traders.
click here to find a list of Carbon suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Carbon DMF (Drug Master File) is a document detailing the whole manufacturing process of Carbon active pharmaceutical ingredient (API) in detail. Different forms of Carbon DMFs exist exist since differing nations have different regulations, such as Carbon USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Carbon DMF submitted to regulatory agencies in the US is known as a USDMF. Carbon USDMF includes data on Carbon's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Carbon USDMF is kept confidential to protect the manufacturer’s intellectual property.
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In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.
Pharmaceutical companies submit a Carbon Drug Master File in Korea (Carbon KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Carbon. The MFDS reviews the Carbon KDMF as part of the drug registration process and uses the information provided in the Carbon KDMF to evaluate the safety and efficacy of the drug.
After submitting a Carbon KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Carbon API can apply through the Korea Drug Master File (KDMF).
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A Carbon CEP of the European Pharmacopoeia monograph is often referred to as a Carbon Certificate of Suitability (COS). The purpose of a Carbon CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Carbon EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Carbon to their clients by showing that a Carbon CEP has been issued for it. The manufacturer submits a Carbon CEP (COS) as part of the market authorization procedure, and it takes on the role of a Carbon CEP holder for the record. Additionally, the data presented in the Carbon CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Carbon DMF.
A Carbon CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Carbon CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.
click here to find a list of Carbon suppliers with CEP (COS) on PharmaCompass.
Carbon Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Carbon GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Carbon GMP manufacturer or Carbon GMP API supplier for your needs.
A Carbon CoA (Certificate of Analysis) is a formal document that attests to Carbon's compliance with Carbon specifications and serves as a tool for batch-level quality control.
Carbon CoA mostly includes findings from lab analyses of a specific batch. For each Carbon CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Carbon may be tested according to a variety of international standards, such as European Pharmacopoeia (Carbon EP), Carbon JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Carbon USP).
