Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

Contact Supplier

Jai Radhe Sales is your partner for all your sourcing needs.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

2 API Suppliers, 1 USDMF, 1 Listed Suppliers

2 API Suppliers
1 USDMF
1 Listed Suppliers

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 89213-87-6, Alpha-atriopeptin, Sun-4936, Atrial natriuretic peptide, 85637-73-6, Atrial natriuretic peptide-28 (human reduced)

Molecular Formula

C₁₂₇H₂₀₃N₄₅O₃₉S₃

Molecular Weight

3080.5 g/mol

InChI Key

NSQLIUXCMFBZME-MPVJKSABSA-N

1 2D Structure

Carperitide

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(4R,10S,16S,19S,22S,28S,31S,34S,37S,40S,49S,52R)-52-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-19-(3-amino-3-oxopropyl)-49-benzyl-28-[(2S)-butan-2-yl]-31,40-bis(3-carbamimidamidopropyl)-34-(carboxymethyl)-16-(hydroxymethyl)-22-methyl-10-(2-methylpropyl)-37-(2-methylsulfanylethyl)-6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51-hexadecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-hexadecazacyclotripentacontane-4-carbonyl]amino]-4-oxobutanoyl]amino]-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid

2.1.2 InChI

InChI=1S/C127H203N45O39S3/c1-9-64(6)99-121(209)150-52-94(182)151-65(7)100(188)155-76(34-35-91(129)179)109(197)167-85(56-174)104(192)149-53-96(184)153-78(43-62(2)3)102(190)148-54-97(185)154-89(119(207)164-82(48-92(130)180)114(202)169-86(57-175)116(204)163-81(46-67-23-14-11-15-24-67)113(201)158-73(27-18-39-143-125(135)136)107(195)166-84(122(210)211)47-68-30-32-69(178)33-31-68)60-213-214-61-90(171-118(206)88(59-177)170-117(205)87(58-176)168-108(196)74(28-19-40-144-126(137)138)156-106(194)72(26-17-38-142-124(133)134)157-112(200)79(44-63(4)5)161-101(189)70(128)55-173)120(208)162-80(45-66-21-12-10-13-22-66)103(191)147-50-93(181)146-51-95(183)152-71(25-16-37-141-123(131)132)105(193)160-77(36-42-212-8)110(198)165-83(49-98(186)187)115(203)159-75(111(199)172-99)29-20-41-145-127(139)140/h10-15,21-24,30-33,62-65,70-90,99,173-178H,9,16-20,25-29,34-61,128H2,1-8H3,(H2,129,179)(H2,130,180)(H,146,181)(H,147,191)(H,148,190)(H,149,192)(H,150,209)(H,151,182)(H,152,183)(H,153,184)(H,154,185)(H,155,188)(H,156,194)(H,157,200)(H,158,201)(H,159,203)(H,160,193)(H,161,189)(H,162,208)(H,163,204)(H,164,207)(H,165,198)(H,166,195)(H,167,197)(H,168,196)(H,169,202)(H,170,205)(H,171,206)(H,172,199)(H,186,187)(H,210,211)(H4,131,132,141)(H4,133,134,142)(H4,135,136,143)(H4,137,138,144)(H4,139,140,145)/t64-,65-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,99-/m0/s1

2.1.3 InChI Key

NSQLIUXCMFBZME-MPVJKSABSA-N

2.1.4 Canonical SMILES

CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)CCSC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CO)N)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC4=CC=C(C=C4)O)C(=O)O)CC(C)C)CO)CCC(=O)N)C

2.1.5 Isomeric SMILES

CC[C@H](C)[C@H]1C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCCNC(=N)N)CC(=O)O)CCSC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC4=CC=C(C=C4)O)C(=O)O)CC(C)C)CO)CCC(=O)N)C

2.2 Synonyms

2.2.1 MeSH Synonyms

1. Alpha-atrial Natriuretic Peptide, Human

2. Alpha-hanp

3. Alpha-human Atrial Natriuretic Peptide

4. Atrial Natriuretic Peptide Precusor A, Human

5. Natriuretic Peptide Precursor A, Human

6. Nppa Protein, Human

2.2.2 Depositor-Supplied Synonyms

1. 89213-87-6

2. Alpha-atriopeptin

3. Sun-4936

4. Atrial Natriuretic Peptide

5. 85637-73-6

6. Atrial Natriuretic Peptide-28 (human Reduced)

7. Sun 4936

8. Atriopeptin

9. Alpha-human Atriopeptin

10. Atriopeptins

11. Cardionatrin

12. Atriopeptin-28 (human)

13. Alpha-atriopeptin (human)

14. Human Atriopeptin(1-28)

15. Auriculin (peptide)

16. Human Atriopeptin(99-126)

17. Ccris 4930

18. Atrial Natriuretic Peptide Human

19. Triopeptin (human Alpha-component)

20. Atrial Natriuretic Hormone

21. Atrial Natriuretic Peptides

22. Carperitide [usan:inn]

23. Alpha-human Atrial Natriuretic Hormone

24. Atrial Natriuretic Factor (99-126)

25. Natriuretic Peptides, Atrial

26. Atrial Natriuretic Peptide A

27. Unii-gz8fa500j0

28. Atrial Natriuretic Polypeptide

29. Alphahanf

30. Atrial Natriuretic Factor

31. Nppa Protein, Human

32. Anp 1-28,human

33. Schembl218549

34. Gz8fa500j0

35. Chembl2104386

36. Alpha-anf(1-28)-human

37. Chebi:135914

38. Dtxsid201346607

39. Bdbm50230986

40. Slrrsscfggrmdrigaqsglgcnsfry-oh

41. Atrial Natriuretic Peptide Carperitide

42. Akos024456845

43. Atriopeptin-33(rat), 1-de-l-leucine-2-de-l-alanine-3-deglycine-4-de-l-proline-5-de-l-arginine-17-l-methionine-

44. L-seryl-l-leucyl-l-arginyl-l-arginyl-l-seryl-l-seryl-l-cysteinyl-l-phenylalanylglycylglycyl-l-arginyl-l-methionyl-l-aspartyl-l-arginyl-l-isoleucylglycyl-l-alanyl-l-glutaminyl-l-serylglycyl-l-leucylglycyl-l-cysteinyl-l-asparaginyl-l-seryl-l-phenylalanyl-l-arginyl-l-tyrosine Cyclic(7->23)-disulfide

45. L-seryl-l-leucyl-l-arginyl-l-arginyl-l-seryl-l-seryl-l-cysteinyl-l-phenylalanylglycylglycyl-l-arginyl-l-methionyl-l-aspartyl-l-arginyl-l-isoleucylglycyl-l-alanyl-l-glutaminyl-l-serylglycyl-l-leucylglycyl-l-cysteinyl-l-asparaginyl-l-seryl-l-phenylalanyl-l-arginyl-l-tyrosine Cyclic(7-23)-disulfide

46. Atrial Natriuretic Factor (1-28) (human)

47. Atrial Natriuretic Peptide (1-28) (human, Porcine)

48. H-ser-leu-arg-arg-ser-ser-cys-phe-gly-gly-arg-met-asp-arg-ile-gly-ala-gln-ser-gly-leu-gly-cys-asn-ser-phe-arg-tyr-oh

2.3 Create Date

2007-07-03

3 Chemical and Physical Properties

Molecular Formula	C₁₂₇H₂₀₃N₄₅O₃₉S₃
Molecular Weight	3080.5 g/mol
XLogP3	-14.9
Hydrogen Bond Donor Count	53
Hydrogen Bond Acceptor Count	48
Rotatable Bond Count	75
Exact Mass	3079.4480502 g/mol
Monoisotopic Mass	3078.4446953 g/mol
Topological Polar Surface Area	1480 Å²
Heavy Atom Count	214
Formal Charge	0
Complexity	6940
Isotope Atom Count	0
Defined Atom Stereocenter Count	24
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1