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Chemistry

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Also known as: 89213-87-6, Alpha-atriopeptin, Sun-4936, Atrial natriuretic peptide, 85637-73-6, Atrial natriuretic peptide-28 (human reduced)
Molecular Formula
C127H203N45O39S3
Molecular Weight
3080.5  g/mol
InChI Key
NSQLIUXCMFBZME-MPVJKSABSA-N

Carperitide
1 2D Structure

Carperitide

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(4R,10S,16S,19S,22S,28S,31S,34S,37S,40S,49S,52R)-52-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-19-(3-amino-3-oxopropyl)-49-benzyl-28-[(2S)-butan-2-yl]-31,40-bis(3-carbamimidamidopropyl)-34-(carboxymethyl)-16-(hydroxymethyl)-22-methyl-10-(2-methylpropyl)-37-(2-methylsulfanylethyl)-6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51-hexadecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-hexadecazacyclotripentacontane-4-carbonyl]amino]-4-oxobutanoyl]amino]-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
2.1.2 InChI
InChI=1S/C127H203N45O39S3/c1-9-64(6)99-121(209)150-52-94(182)151-65(7)100(188)155-76(34-35-91(129)179)109(197)167-85(56-174)104(192)149-53-96(184)153-78(43-62(2)3)102(190)148-54-97(185)154-89(119(207)164-82(48-92(130)180)114(202)169-86(57-175)116(204)163-81(46-67-23-14-11-15-24-67)113(201)158-73(27-18-39-143-125(135)136)107(195)166-84(122(210)211)47-68-30-32-69(178)33-31-68)60-213-214-61-90(171-118(206)88(59-177)170-117(205)87(58-176)168-108(196)74(28-19-40-144-126(137)138)156-106(194)72(26-17-38-142-124(133)134)157-112(200)79(44-63(4)5)161-101(189)70(128)55-173)120(208)162-80(45-66-21-12-10-13-22-66)103(191)147-50-93(181)146-51-95(183)152-71(25-16-37-141-123(131)132)105(193)160-77(36-42-212-8)110(198)165-83(49-98(186)187)115(203)159-75(111(199)172-99)29-20-41-145-127(139)140/h10-15,21-24,30-33,62-65,70-90,99,173-178H,9,16-20,25-29,34-61,128H2,1-8H3,(H2,129,179)(H2,130,180)(H,146,181)(H,147,191)(H,148,190)(H,149,192)(H,150,209)(H,151,182)(H,152,183)(H,153,184)(H,154,185)(H,155,188)(H,156,194)(H,157,200)(H,158,201)(H,159,203)(H,160,193)(H,161,189)(H,162,208)(H,163,204)(H,164,207)(H,165,198)(H,166,195)(H,167,197)(H,168,196)(H,169,202)(H,170,205)(H,171,206)(H,172,199)(H,186,187)(H,210,211)(H4,131,132,141)(H4,133,134,142)(H4,135,136,143)(H4,137,138,144)(H4,139,140,145)/t64-,65-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,99-/m0/s1
2.1.3 InChI Key
NSQLIUXCMFBZME-MPVJKSABSA-N
2.1.4 Canonical SMILES
CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)CCSC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CO)N)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC4=CC=C(C=C4)O)C(=O)O)CC(C)C)CO)CCC(=O)N)C
2.1.5 Isomeric SMILES
CC[C@H](C)[C@H]1C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCCNC(=N)N)CC(=O)O)CCSC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC4=CC=C(C=C4)O)C(=O)O)CC(C)C)CO)CCC(=O)N)C
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Alpha-atrial Natriuretic Peptide, Human

2. Alpha-hanp

3. Alpha-human Atrial Natriuretic Peptide

4. Atrial Natriuretic Peptide Precusor A, Human

5. Natriuretic Peptide Precursor A, Human

6. Nppa Protein, Human

2.2.2 Depositor-Supplied Synonyms

1. 89213-87-6

2. Alpha-atriopeptin

3. Sun-4936

4. Atrial Natriuretic Peptide

5. 85637-73-6

6. Atrial Natriuretic Peptide-28 (human Reduced)

7. Sun 4936

8. Atriopeptin

9. Alpha-human Atriopeptin

10. Atriopeptins

11. Cardionatrin

12. Atriopeptin-28 (human)

13. Alpha-atriopeptin (human)

14. Human Atriopeptin(1-28)

15. Auriculin (peptide)

16. Human Atriopeptin(99-126)

17. Ccris 4930

18. Atrial Natriuretic Peptide Human

19. Triopeptin (human Alpha-component)

20. Atrial Natriuretic Hormone

21. Atrial Natriuretic Peptides

22. Carperitide [usan:inn]

23. Alpha-human Atrial Natriuretic Hormone

24. Atrial Natriuretic Factor (99-126)

25. Natriuretic Peptides, Atrial

26. Atrial Natriuretic Peptide A

27. Unii-gz8fa500j0

28. Atrial Natriuretic Polypeptide

29. Alphahanf

30. Atrial Natriuretic Factor

31. Nppa Protein, Human

32. Anp 1-28,human

33. Schembl218549

34. Gz8fa500j0

35. Chembl2104386

36. Alpha-anf(1-28)-human

37. Chebi:135914

38. Dtxsid201346607

39. Bdbm50230986

40. Slrrsscfggrmdrigaqsglgcnsfry-oh

41. Atrial Natriuretic Peptide Carperitide

42. Akos024456845

43. Atriopeptin-33(rat), 1-de-l-leucine-2-de-l-alanine-3-deglycine-4-de-l-proline-5-de-l-arginine-17-l-methionine-

44. L-seryl-l-leucyl-l-arginyl-l-arginyl-l-seryl-l-seryl-l-cysteinyl-l-phenylalanylglycylglycyl-l-arginyl-l-methionyl-l-aspartyl-l-arginyl-l-isoleucylglycyl-l-alanyl-l-glutaminyl-l-serylglycyl-l-leucylglycyl-l-cysteinyl-l-asparaginyl-l-seryl-l-phenylalanyl-l-arginyl-l-tyrosine Cyclic(7->23)-disulfide

45. L-seryl-l-leucyl-l-arginyl-l-arginyl-l-seryl-l-seryl-l-cysteinyl-l-phenylalanylglycylglycyl-l-arginyl-l-methionyl-l-aspartyl-l-arginyl-l-isoleucylglycyl-l-alanyl-l-glutaminyl-l-serylglycyl-l-leucylglycyl-l-cysteinyl-l-asparaginyl-l-seryl-l-phenylalanyl-l-arginyl-l-tyrosine Cyclic(7-23)-disulfide

46. Atrial Natriuretic Factor (1-28) (human)

47. Atrial Natriuretic Peptide (1-28) (human, Porcine)

48. H-ser-leu-arg-arg-ser-ser-cys-phe-gly-gly-arg-met-asp-arg-ile-gly-ala-gln-ser-gly-leu-gly-cys-asn-ser-phe-arg-tyr-oh

2.3 Create Date
2007-07-03
3 Chemical and Physical Properties
Molecular Weight 3080.5 g/mol
Molecular Formula C127H203N45O39S3
XLogP3-14.9
Hydrogen Bond Donor Count53
Hydrogen Bond Acceptor Count48
Rotatable Bond Count75
Exact Mass3079.4480502 g/mol
Monoisotopic Mass3078.4446953 g/mol
Topological Polar Surface Area1480 Ų
Heavy Atom Count214
Formal Charge0
Complexity6940
Isotope Atom Count0
Defined Atom Stereocenter Count24
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Carperitide Manufacturers

A Carperitide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Carperitide, including repackagers and relabelers. The FDA regulates Carperitide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Carperitide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Carperitide manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Carperitide Suppliers

A Carperitide supplier is an individual or a company that provides Carperitide active pharmaceutical ingredient (API) or Carperitide finished formulations upon request. The Carperitide suppliers may include Carperitide API manufacturers, exporters, distributors and traders.

click here to find a list of Carperitide suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Carperitide USDMF

A Carperitide DMF (Drug Master File) is a document detailing the whole manufacturing process of Carperitide active pharmaceutical ingredient (API) in detail. Different forms of Carperitide DMFs exist exist since differing nations have different regulations, such as Carperitide USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Carperitide DMF submitted to regulatory agencies in the US is known as a USDMF. Carperitide USDMF includes data on Carperitide's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Carperitide USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Carperitide suppliers with USDMF on PharmaCompass.

Carperitide GMP

Carperitide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Carperitide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Carperitide GMP manufacturer or Carperitide GMP API supplier for your needs.

Carperitide CoA

A Carperitide CoA (Certificate of Analysis) is a formal document that attests to Carperitide's compliance with Carperitide specifications and serves as a tool for batch-level quality control.

Carperitide CoA mostly includes findings from lab analyses of a specific batch. For each Carperitide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Carperitide may be tested according to a variety of international standards, such as European Pharmacopoeia (Carperitide EP), Carperitide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Carperitide USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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