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    Chemistry

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    Also known as:
    Molecular Formula
    C12H15N5O3
    Molecular Weight
    277.28  g/mol
    InChI Key
    QDGZDCVAUDNJFG-FXQIFTODSA-N
    Entecavir
    1 2D Structure

    Entecavir

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one
    2.1.2 InChI
    InChI=1S/C12H15N5O3/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20)/t6-,7-,8-/m0/s1
    2.1.3 InChI Key
    QDGZDCVAUDNJFG-FXQIFTODSA-N
    2.1.4 Canonical SMILES
    C=C1C(CC(C1CO)O)N2C=NC3=C2NC(=NC3=O)N
    2.1.5 Isomeric SMILES
    C=C1[C@H](C[C@@H]([C@H]1CO)O)N2C=NC3=C2NC(=NC3=O)N
    2.2 Create Date
    2005-08-01
    3 Chemical and Physical Properties
    Molecular Weight 277.28 g/mol
    Molecular Formula C12H15N5O3
    XLogP3-0.8
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count2
    Exact Mass277.11748936 g/mol
    Monoisotopic Mass277.11748936 g/mol
    Topological Polar Surface Area126 A^2
    Heavy Atom Count20
    Formal Charge0
    Complexity480
    Isotope Atom Count0
    Defined Atom Stereocenter Count3
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 4  
    Drug NameBaraclude
    PubMed HealthEntecavir (By mouth)
    Drug ClassesAntiviral
    Drug LabelBARACLUDE is the tradename for entecavir, a guanosine nucleoside analogue with selective activity against HBV. The chemical name for entecavir is 2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one,...
    Active IngredientEntecavir
    Dosage FormTablet; Solution
    RouteOral
    Strength0.5mg; 0.05mg/ml; 1mg
    Market StatusPrescription
    CompanyBristol Myers Squibb

    2 of 4  
    Drug NameEntecavir
    PubMed HealthEntecavir (By mouth)
    Drug ClassesAntiviral
    Drug LabelBARACLUDE is the tradename for entecavir, a guanosine nucleoside analogue with selective activity against HBV. The chemical name for entecavir is 2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one,...
    Active IngredientEntecavir
    Dosage FormTablet
    RouteOral
    Strength0.5mg; 1mg
    Market StatusPrescription
    CompanyTeva Pharms Usa

    3 of 4  
    Drug NameBaraclude
    PubMed HealthEntecavir (By mouth)
    Drug ClassesAntiviral
    Drug LabelBARACLUDE is the tradename for entecavir, a guanosine nucleoside analogue with selective activity against HBV. The chemical name for entecavir is 2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one,...
    Active IngredientEntecavir
    Dosage FormTablet; Solution
    RouteOral
    Strength0.5mg; 0.05mg/ml; 1mg
    Market StatusPrescription
    CompanyBristol Myers Squibb

    4 of 4  
    Drug NameEntecavir
    PubMed HealthEntecavir (By mouth)
    Drug ClassesAntiviral
    Drug LabelBARACLUDE is the tradename for entecavir, a guanosine nucleoside analogue with selective activity against HBV. The chemical name for entecavir is 2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one,...
    Active IngredientEntecavir
    Dosage FormTablet
    RouteOral
    Strength0.5mg; 1mg
    Market StatusPrescription
    CompanyTeva Pharms Usa

    API Reference Price

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","customerCountry":"INDIA","quantity":"0.20","actualQuantity":"0.2","unit":"KGS","unitRateFc":"178000","totalValueFC":"35737.2","currency":"USD","unitRateINR":"14320100","date":"15-Sep-2022","totalValueINR":"2864020","totalValueInUsd":"35737.2","indian_port":"HYDERABAD AIR","hs_no":"29335990","bill_no":"2458439","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"PLOT NO.26 & 27, FIRST FLOOR, TECHNOCRATS INDUSTRIAL ESTATE, Cont"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1663871400,"product":"ENTECAVIR MONOHYDRATE (CEP GRADE ) (275 GRAM) [TL NO.:TL\/WZ\/22\/002876 DT.25\/07\/2022]","address":"PLOT NO.H-19,MIDC,WALUJ AURANGABAD","city":"AURANGABAD,MAHARASHTRA","supplier":"BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO.,LTD","supplierCountry":"CHINA","foreign_port":"NA","customer":"RV LIFESCIENCES LIMITED","customerCountry":"INDIA","quantity":"0.28","actualQuantity":"0.275","unit":"KGS","unitRateFc":"65000","totalValueFC":"17932.8","currency":"USD","unitRateINR":"5226000","date":"23-Sep-2022","totalValueINR":"1437150","totalValueInUsd":"17932.8","indian_port":"BOMBAY AIR","hs_no":"29419030","bill_no":"2577601","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"PLOT NO.H-19,MIDC,WALUJ AURANGABAD"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1666636200,"product":"ENTECAVIR MONOHYDRATE","address":"NATCO HOUSE, ROAD NO.2,,BANJARA H ILLS,","city":"HYDERABAD,TELANGANA","supplier":"M\/S. SHANGHAI LIGHT INDUSTRIAL PRODUCTS","supplierCountry":"CHINA","foreign_port":"NA","customer":"NATCO PHARMA","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"128000","totalValueFC":"130513.5","currency":"USD","unitRateINR":"10739200","date":"25-Oct-2022","totalValueINR":"10739200","totalValueInUsd":"130513.5","indian_port":"HYDERABAD AIR","hs_no":"29335990","bill_no":"3031102","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"NATCO HOUSE, ROAD NO.2,,BANJARA H ILLS,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1692210600,"product":"ENTECAVIR MONOHYDRATE QTY: 200 GRAMS AS PER INV","address":"NA","city":"NA","supplier":"WELDING GMBH & CO.KG","supplierCountry":"CHINA","foreign_port":"NA","customer":"COHANCE LIFESCIENCES","customerCountry":"INDIA","quantity":"0.20","actualQuantity":"0.2","unit":"KGS","unitRateFc":"178000","totalValueFC":"35856.3","currency":"USD","unitRateINR":"14702528","date":"17-Aug-2023","totalValueINR":"2970207.68","totalValueInUsd":"35856.3","indian_port":"HYDERABAD AIR","hs_no":"29335990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"NA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1706034600,"product":"ENTECAVIR MONOHYDRATE USP (590 G) CAS NO.142217-69-4 2-AMINO-9-[(1S,3R,4S)-4-HYDROXY-3- (HYDROXYMETHYL)-2-METHYLIDENE","address":"H.O.ANJALI COMPLEX,","city":"AURANGABAD ,MAHARASHTRA","supplier":"BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO.,LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"RV LIFESCIENCES LIMITED","customerCountry":"INDIA","quantity":"0.59","actualQuantity":"0.59","unit":"KGS","unitRateFc":"35593.2","totalValueFC":"21249.7","currency":"USD","unitRateINR":"2993389.8","date":"24-Jan-2024","totalValueINR":"1766100","totalValueInUsd":"21249.7","indian_port":"Bombay Air","hs_no":"29051990","bill_no":"9808092","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"BUILDING C25-C28, NO.218 XINGHUROAD, SUZHOU IND PARKSUZHOU P.R. CHINA CHINA","customerAddress":"H.O.ANJALI COMPLEX,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1706553000,"product":"ENTECAVIR MONOHYDRATE(400 GMS)","address":"Plot No. 26 & 27, Technocrat Industrial Estate (TIE)","city":"Hyderabad","supplier":"WELDING GMBH & CO.KG","supplierCountry":"GERMANY","foreign_port":"HANGCHOW (HANGZHOU)","customer":"COHANCE LIFESCIENCES","customerCountry":"INDIA","quantity":"0.40","actualQuantity":"0.4","unit":"KGS","unitRateFc":"178000","totalValueFC":"72046.7","currency":"USD","unitRateINR":"14969800","date":"30-Jan-2024","totalValueINR":"5987920","totalValueInUsd":"72046.7","indian_port":"Hyderabad Air","hs_no":"29335990","bill_no":"9904457","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"HANGCHOW (HANGZHOU)","supplierAddress":"Esplanade 3920354Hamburg GERMANY","customerAddress":"Plot No. 26 & 27, Technocrat Industrial Estate (TIE)"}]
    15-Jan-2021
    17-Mar-2025
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    DOSAGE - TABLET;ORAL - 0.5MG

    USFDA APPLICATION NUMBER - 21797

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    DOSAGE - TABLET;ORAL - 1MG

    USFDA APPLICATION NUMBER - 21797

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    DOSAGE - SOLUTION;ORAL - 0.05MG/ML

    USFDA APPLICATION NUMBER - 21798

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    ABOUT THIS PAGE

    Looking for / Entecavir API manufacturers, exporters & distributors?

    Entecavir manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Entecavir API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Entecavir manufacturer or Entecavir supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Entecavir manufacturer or Entecavir supplier.

    PharmaCompass also assists you with knowing the Entecavir API Price utilized in the formulation of products. Entecavir API Price is not always fixed or binding as the Entecavir Price is obtained through a variety of data sources. The Entecavir Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Entecavir

    CAS-142217-69-4 Manufacturers

    A CAS-142217-69-4 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of CAS-142217-69-4, including repackagers and relabelers. The FDA regulates CAS-142217-69-4 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. CAS-142217-69-4 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of CAS-142217-69-4 manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    CAS-142217-69-4 Suppliers

    A CAS-142217-69-4 supplier is an individual or a company that provides CAS-142217-69-4 active pharmaceutical ingredient (API) or CAS-142217-69-4 finished formulations upon request. The CAS-142217-69-4 suppliers may include CAS-142217-69-4 API manufacturers, exporters, distributors and traders.

    click here to find a list of CAS-142217-69-4 suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    CAS-142217-69-4 USDMF

    A CAS-142217-69-4 DMF (Drug Master File) is a document detailing the whole manufacturing process of CAS-142217-69-4 active pharmaceutical ingredient (API) in detail. Different forms of CAS-142217-69-4 DMFs exist exist since differing nations have different regulations, such as CAS-142217-69-4 USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A CAS-142217-69-4 DMF submitted to regulatory agencies in the US is known as a USDMF. CAS-142217-69-4 USDMF includes data on CAS-142217-69-4's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The CAS-142217-69-4 USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of CAS-142217-69-4 suppliers with USDMF on PharmaCompass.

    CAS-142217-69-4 JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The CAS-142217-69-4 Drug Master File in Japan (CAS-142217-69-4 JDMF) empowers CAS-142217-69-4 API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the CAS-142217-69-4 JDMF during the approval evaluation for pharmaceutical products. At the time of CAS-142217-69-4 JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of CAS-142217-69-4 suppliers with JDMF on PharmaCompass.

    CAS-142217-69-4 KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a CAS-142217-69-4 Drug Master File in Korea (CAS-142217-69-4 KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of CAS-142217-69-4. The MFDS reviews the CAS-142217-69-4 KDMF as part of the drug registration process and uses the information provided in the CAS-142217-69-4 KDMF to evaluate the safety and efficacy of the drug.

    After submitting a CAS-142217-69-4 KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their CAS-142217-69-4 API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of CAS-142217-69-4 suppliers with KDMF on PharmaCompass.

    CAS-142217-69-4 CEP

    A CAS-142217-69-4 CEP of the European Pharmacopoeia monograph is often referred to as a CAS-142217-69-4 Certificate of Suitability (COS). The purpose of a CAS-142217-69-4 CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of CAS-142217-69-4 EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of CAS-142217-69-4 to their clients by showing that a CAS-142217-69-4 CEP has been issued for it. The manufacturer submits a CAS-142217-69-4 CEP (COS) as part of the market authorization procedure, and it takes on the role of a CAS-142217-69-4 CEP holder for the record. Additionally, the data presented in the CAS-142217-69-4 CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the CAS-142217-69-4 DMF.

    A CAS-142217-69-4 CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. CAS-142217-69-4 CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of CAS-142217-69-4 suppliers with CEP (COS) on PharmaCompass.

    CAS-142217-69-4 WC

    A CAS-142217-69-4 written confirmation (CAS-142217-69-4 WC) is an official document issued by a regulatory agency to a CAS-142217-69-4 manufacturer, verifying that the manufacturing facility of a CAS-142217-69-4 active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting CAS-142217-69-4 APIs or CAS-142217-69-4 finished pharmaceutical products to another nation, regulatory agencies frequently require a CAS-142217-69-4 WC (written confirmation) as part of the regulatory process.

    click here to find a list of CAS-142217-69-4 suppliers with Written Confirmation (WC) on PharmaCompass.

    CAS-142217-69-4 NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing CAS-142217-69-4 as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for CAS-142217-69-4 API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture CAS-142217-69-4 as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain CAS-142217-69-4 and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a CAS-142217-69-4 NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of CAS-142217-69-4 suppliers with NDC on PharmaCompass.

    CAS-142217-69-4 GMP

    CAS-142217-69-4 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of CAS-142217-69-4 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right CAS-142217-69-4 GMP manufacturer or CAS-142217-69-4 GMP API supplier for your needs.

    CAS-142217-69-4 CoA

    A CAS-142217-69-4 CoA (Certificate of Analysis) is a formal document that attests to CAS-142217-69-4's compliance with CAS-142217-69-4 specifications and serves as a tool for batch-level quality control.

    CAS-142217-69-4 CoA mostly includes findings from lab analyses of a specific batch. For each CAS-142217-69-4 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    CAS-142217-69-4 may be tested according to a variety of international standards, such as European Pharmacopoeia (CAS-142217-69-4 EP), CAS-142217-69-4 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (CAS-142217-69-4 USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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