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Chemistry

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Also known as: 66-22-8, 2,4-dihydroxypyrimidine, 2,4(1h,3h)-pyrimidinedione, 2,4-pyrimidinediol, Pyrimidine-2,4(1h,3h)-dione, 2,4-dioxopyrimidine
Molecular Formula
C4H4N2O2
Molecular Weight
112.09  g/mol
InChI Key
ISAKRJDGNUQOIC-UHFFFAOYSA-N
FDA UNII
56HH86ZVCT

Uracil
One of four nucleotide bases in the nucleic acid RNA.
1 2D Structure

Uracil

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1H-pyrimidine-2,4-dione
2.1.2 InChI
InChI=1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)
2.1.3 InChI Key
ISAKRJDGNUQOIC-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=CNC(=O)NC1=O
2.2 Other Identifiers
2.2.1 UNII
56HH86ZVCT
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 66-22-8

2. 2,4-dihydroxypyrimidine

3. 2,4(1h,3h)-pyrimidinedione

4. 2,4-pyrimidinediol

5. Pyrimidine-2,4(1h,3h)-dione

6. 2,4-dioxopyrimidine

7. Pyrod

8. Pyrimidine-2,4-diol

9. Hybar X

10. 2,4-pyrimidinedione

11. Pirod

12. 1h-pyrimidine-2,4-dione

13. 51953-14-1

14. Uracil [usan]

15. Ru 12709

16. Ura

17. Mfcd00006016

18. Ccris 3077

19. Uracyl

20. Urazil

21. 2-hydroxy-4(3h)-pyrimidinone

22. Sq 6201

23. Sq 7726

24. Sq 8493

25. Chebi:17568

26. 1,2,3,4-tetrahydropyrimidine-2,4-dione

27. Bms 205603-01

28. Ai3-25470

29. Nsc 3970

30. Nsc-3970

31. Sq-6201

32. Sq-7726

33. Sq-8493

34. Lamivudine Impurity E

35. 2-hydroxy-4(1h)-pyrimidinone

36. Bms-205603-01

37. Lamivudine Impurity E Rs

38. 144104-68-7

39. 66255-05-8

40. 56hh86zvct

41. 4-hydroxy-2(1h)-pyrimidinone

42. Fluorouracil Specified Compound C

43. Nsc3970

44. Ncgc00181030-01

45. Dsstox_cid_1424

46. Dsstox_rid_76153

47. Dsstox_gsid_21424

48. 4-hydroxyuracil

49. Cas-66-22-8

50. Cid 5274267

51. Uracil (8ci)

52. Uracil [usan:jan]

53. Einecs 200-621-9

54. Unii-56hh86zvct

55. 2,4-pyrimidinediol (9ci)

56. 4(3h)-pyrimidinone, 2-hydroxy- (9ci)

57. 8h-uracil

58. Hydroxypyrimidinone

59. 2,6-dioxypyrimidin

60. Uracil,(s)

61. 2,4-dioxypyrimidine

62. 2,4(1h,3h)-pyrimidinedione (9ci)

63. Pyrimidine-2,4-dione

64. Fluorouracil Impurity C

65. Uracil, 99%

66. 1ui0

67. Uracil (jan/usan)

68. 2,3h)-pyrimidinedione

69. 2,6-dihydroxypyrimidine

70. Uracil [inci]

71. Uracil [jan]

72. Uracil [usp-rs]

73. Uracil [who-dd]

74. Uracil [mi]

75. Uracil [mart.]

76. Bmse000187

77. Bmse000940

78. Chembl566

79. Epitope Id:120356

80. Ncimech_000782

81. Schembl8235

82. Uracil, >=99.0%

83. Mls001304993

84. Gtpl4560

85. 2,4-(1h,3h)-pyrimidinedione

86. Dtxsid4021424

87. 1h-pyrimidine-2,4-dione;uracil

88. Uracil, >=99.0% (t)

89. Hms2234e19

90. Hms3264c13

91. Hms3373e18

92. Hms3652n05

93. Pharmakon1600-01502345

94. Zinc895045

95. Bcp26546

96. Hy-i0960

97. Nsc29742

98. Tox21_112680

99. Tox21_201023

100. Bdbm50549809

101. Ccg-35866

102. Nsc-29742

103. Nsc759649

104. S4177

105. Stk301734

106. Stl124066

107. Akos000119989

108. Akos002303991

109. Tox21_112680_1

110. 4(3h)-pyrimidinone,2-hydroxy-(9ci)

111. Am83913

112. Ccg-213042

113. Cs-w020104

114. Db03419

115. Nsc-759649

116. Ps-5279

117. Sb55489

118. Sb55884

119. Ncgc00181030-02

120. Ncgc00247663-01

121. Ncgc00258576-01

122. Uracil, Vetec(tm) Reagent Grade, 98%

123. Nci60_003718

124. Pyrimidine-2,4(1h,3h)-dione (uracil)

125. Smr000752912

126. Sy008943

127. Uracil 1000 Microg/ml In Methanol:water

128. Db-030518

129. Db-103964

130. Lamivudine Impurity F [ep Impurity]

131. Bb 0242167

132. Fluorouracil Impurity C [ep Impurity]

133. Ft-0609769

134. Ft-0694063

135. Ft-0695907

136. Ft-0695908

137. Ft-0773727

138. Lamivudine Impurity E [usp Impurity]

139. Sw220239-1

140. U0013

141. Uracil, Suitable For Cell Culture, Bioreagent

142. C00106

143. D00027

144. Ab00171810_03

145. Ab00171810_04

146. Ab00918623-05

147. A835376

148. Ac-907/30002021

149. Q182990

150. Z56889474

151. F1796-0008

152. Fluorouracil Specified Compound C [usp Impurity]

153. E2fc11e5-1887-46df-b415-82313ce9b2bd

154. Uracil, United States Pharmacopeia (usp) Reference Standard

155. Fluorouracil Impurity C, European Pharmacopoeia (ep) Reference Standard

156. Uracil, Pharmaceutical Secondary Standard; Certified Reference Material

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 112.09 g/mol
Molecular Formula C4H4N2O2
XLogP3-1.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass112.027277375 g/mol
Monoisotopic Mass112.027277375 g/mol
Topological Polar Surface Area58.2 Ų
Heavy Atom Count8
Formal Charge0
Complexity161
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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01

Sakar Healthcare

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Uracil

About the Company : Established in the year 2004, Sakar is engaged in manufacturing of Pharmaceutical products providing Liquid Orals, Cephalosporin Tablet, Capsule, Dry Powder Syrup, Dry Powder Injec...

Established in the year 2004, Sakar is engaged in manufacturing of Pharmaceutical products providing Liquid Orals, Cephalosporin Tablet, Capsule, Dry Powder Syrup, Dry Powder Injections, Liquid Injectables (SVP) in Ampoules and Vials & Lyophilized Injections. Sakar is managed by a team of professionals with an endeavour to offer Quality Pharmaceutical & Health Care Products in various countries. The company operates as contract development and manufacturing organisation (CDMO), being the EU GMP approved CMO for leading multinational pharmaceutical companies.
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NO.:52)","address":"2ND FLOOR, CHINUBHAI CENTRE,,OFF.","city":"AHMEDABAD,GUJARAT","supplier":"WELDING GMBH & CO.KG","supplierCountry":"CHINA","foreign_port":"PUDONG\/SHANGHAI","customer":"INTAS PHARMACEUTICALS","customerCountry":"INDIA","quantity":"1000.00","actualQuantity":"1000","unit":"KGS","unitRateFc":"273","totalValueFC":"276161.8","currency":"USD","unitRateINR":"23164.1","date":"21-Aug-2024","totalValueINR":"23164050","totalValueInUsd":"276161.8","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29335990","bill_no":"5159879","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"PUDONG\/SHANGHAI","supplierAddress":"Esplanade 39 20354 Hamburg SDNF Germany","customerAddress":"2ND FLOOR, CHINUBHAI CENTRE,,OFF."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727634600,"product":"5-TRIFLUOROMETHYLURACIL 98% MIN CAS NO.: 54-20-6","address":"62, WADIA BLDG, 3RD FLOOR,","city":"FORT, MUMBAI, MAHARASHTRA","supplier":"ZHEJIANG CHEMICALS I & E CORP","supplierCountry":"CHINA","foreign_port":"GUANGZHOU","customer":"RUDRA SPECIALITY CHEM ","customerCountry":"INDIA","quantity":"35.00","actualQuantity":"35","unit":"KGS","unitRateFc":"400","totalValueFC":"14133.4","currency":"USD","unitRateINR":"33840","date":"30-Sep-2024","totalValueINR":"1184400","totalValueInUsd":"14133.4","indian_port":"Bombay Air","hs_no":"29333990","bill_no":"5877724","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"GUANGZHOU","supplierAddress":"10F , BUILDING 4, TAIPING FINANCE TOWER, NO.199 SHIMIN STREET, SHANGCHENG DISTRICT,HANGZHOU CHINA","customerAddress":"62, WADIA BLDG, 3RD FLOOR,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727634600,"product":"5-FLUOROURACIL USP","address":"UNIT NO.24 STEEL MADE INDL.ESTATE","city":"MUMBAI","supplier":"NANTONG JINGHUA PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ENCUBE ETHICALS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"600","totalValueFC":"605.7","currency":"USD","unitRateINR":"50760","date":"30-Sep-2024","totalValueINR":"50760","totalValueInUsd":"605.7","indian_port":"Bombay Air","hs_no":"29335990","bill_no":"5878787","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"LTD. NO.20, 3 HAIBIN ROAD, YANHAI ECONOMIC DEVELOPMENT ZONE RUDONG, NANTONG, JIANGSU CN","customerAddress":"UNIT NO.24 STEEL MADE INDL.ESTATE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1727980200,"product":"5-ETHYLURACIL CAS NO: 4212-49-1","address":"ROOM NO.17, HARSHA CO-OP. HSG. SOC.","city":"NAVI MUMBAI, MAHARASHTRA.","supplier":"USUN FINE CHEMICAL ","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"EBURON ORGANICS","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"320","totalValueFC":"1615.7","currency":"USD","unitRateINR":"27152","date":"04-Oct-2024","totalValueINR":"135760","totalValueInUsd":"1615.7","indian_port":"Bombay Air","hs_no":"29335990","bill_no":"5939676","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"UNIT B, 21\/F, THE HEMISPHERES, 3 GO RDON ROAD, NORTH POINT, HONG KONG SDNF HONG KONG","customerAddress":"ROOM NO.17, HARSHA CO-OP. HSG. SOC."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1728498600,"product":"6-CHLORO-3-METHYLURACIL","address":"2 FLR.PRESTIGE PLAZA","city":"AKOTA BARODA","supplier":"HANGZHOU CELOR CHEMICAL","supplierCountry":"CHINA","foreign_port":"HANGCHOW (HANGZHOU)","customer":"AMI LIFESCIENCES PRIVATE LIMITED","customerCountry":"INDIA","quantity":"55.00","actualQuantity":"55","unit":"KGS","unitRateFc":"72","totalValueFC":"3998.8","currency":"USD","unitRateINR":"6109.2","date":"10-Oct-2024","totalValueINR":"336006","totalValueInUsd":"3998.8","indian_port":"Bombay Air","hs_no":"29335990","bill_no":"6045983","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HANGCHOW (HANGZHOU)","supplierAddress":"BLOCK E-1804 WANTONG CENTRE, 189 DAGUAN ROAD, HANGZHOU CHINA","customerAddress":"2 FLR.PRESTIGE PLAZA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729449000,"product":"5-(TRIFLUOROMETHYL)URACIL","address":"R.S.NO.578 VILLAGAE- LUNA","city":"VADODARA GUJARAT","supplier":"M\/S. TAIZHOU CRENE BIOTECHNOLOGY CO.,LTD","supplierCountry":"CHINA","foreign_port":"HONG KONG","customer":"BDR LIFESCIENCES PRIVATE LIMITED","customerCountry":"INDIA","quantity":"35.00","actualQuantity":"35","unit":"KGS","unitRateFc":"515","totalValueFC":"18223.1","currency":"USD","unitRateINR":"43749.3","date":"21-Oct-2024","totalValueINR":"1531223.75","totalValueInUsd":"18223.1","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"6246187","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HONG KONG","supplierAddress":"ECONOMIC DEVELOPED ZONE OF TAIZHOU ZHEJIANG CHINA CN","customerAddress":"R.S.NO.578 VILLAGAE- LUNA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1730053800,"product":"5-FLUOROURACIL USP","address":"UNIT NO.24 STEEL MADE INDL.ESTATE","city":"MUMBAI","supplier":"NANTONG JINGHUA PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"ENCUBE ETHICALS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"600","totalValueFC":"3033","currency":"USD","unitRateINR":"50970","date":"28-Oct-2024","totalValueINR":"254850","totalValueInUsd":"3033","indian_port":"Bombay Air","hs_no":"29335990","bill_no":"6370080","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"LTD. 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SOC.","city":"NAVI MUMBAI, MAHARASHTRA.","supplier":"USUN FINE CHEMICAL ","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"EBURON ORGANICS","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"320","totalValueFC":"1617.3","currency":"USD","unitRateINR":"27296","date":"18-Nov-2024","totalValueINR":"136480","totalValueInUsd":"1617.3","indian_port":"Bombay Air","hs_no":"29335990","bill_no":"6746177","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"UNIT B, 21\/F, THE HEMISPHERES, 3 GO RDON ROAD, NORTH POINT, SDNF HONG KONG","customerAddress":"ROOM NO.17, HARSHA CO-OP. HSG. SOC."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732213800,"product":"5-FLUOROURACIL USP FDA","address":"UNIT NO.24 STEEL MADE INDL.ESTATE","city":"MUMBAI","supplier":"NANTONG JINGHUA PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ENCUBE ETHICALS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"15.00","actualQuantity":"15","unit":"KGS","unitRateFc":"600","totalValueFC":"9102.6","currency":"USD","unitRateINR":"51210","date":"22-Nov-2024","totalValueINR":"768150","totalValueInUsd":"9102.6","indian_port":"Bombay Air","hs_no":"29335990","bill_no":"6809990","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"LTD. NO.20, 3 HAIBIN ROAD, YANHAI ECONOMIC DEVELOPMENT ZONE RUDONG, NANTONG, JIANGSU CN","customerAddress":"UNIT NO.24 STEEL MADE INDL.ESTATE"}]
15-Jan-2021
22-Nov-2024
KGS
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
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FDF Dossiers

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01

Duphat
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Tegafur; Uracil

Brand Name :

Dosage Form : Capsules

Dosage Strength : 100; 224

Packaging : 1 x 14’s Blister (Alu-PVC)

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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Others

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01

USP

U.S.A
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Duphat
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USP

U.S.A
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Uracil (15 mg)

CAS Number : 66-22-8

Quantity Per Vial : 15

Sale Unit : mg

Price : $250.00

Details : Material Origin- Chemical Synthesis; USMCA- N...

Monograph :

Storage :

Code/Batch No : Catalog #1705753 / F1K302

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02

USP

U.S.A
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Duphat
Not Confirmed

USP

U.S.A
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Not Confirmed

Uracil Arabinoside (50 mg)

CAS Number : 3083-77-0

Quantity Per Vial : 50

Sale Unit : mg

Price : $250.00

Details : Material Origin- Chemical Synthesis; USMCA- N...

Monograph :

Storage :

Code/Batch No : Catalog #1705800 / R131F0

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ABOUT THIS PAGE

CAS-66-22-8 Manufacturers

A CAS-66-22-8 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of CAS-66-22-8, including repackagers and relabelers. The FDA regulates CAS-66-22-8 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. CAS-66-22-8 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of CAS-66-22-8 manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

CAS-66-22-8 Suppliers

A CAS-66-22-8 supplier is an individual or a company that provides CAS-66-22-8 active pharmaceutical ingredient (API) or CAS-66-22-8 finished formulations upon request. The CAS-66-22-8 suppliers may include CAS-66-22-8 API manufacturers, exporters, distributors and traders.

click here to find a list of CAS-66-22-8 suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

CAS-66-22-8 GMP

CAS-66-22-8 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of CAS-66-22-8 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right CAS-66-22-8 GMP manufacturer or CAS-66-22-8 GMP API supplier for your needs.

CAS-66-22-8 CoA

A CAS-66-22-8 CoA (Certificate of Analysis) is a formal document that attests to CAS-66-22-8's compliance with CAS-66-22-8 specifications and serves as a tool for batch-level quality control.

CAS-66-22-8 CoA mostly includes findings from lab analyses of a specific batch. For each CAS-66-22-8 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

CAS-66-22-8 may be tested according to a variety of international standards, such as European Pharmacopoeia (CAS-66-22-8 EP), CAS-66-22-8 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (CAS-66-22-8 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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