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Chemistry

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Also known as: 2468-21-5, Catharanthin, Catharanthine base, (+)-catharanthine, (+)-3,4-didehydrocoronaridine, Wt0yjv846j
Molecular Formula
C21H24N2O2
Molecular Weight
336.4  g/mol
InChI Key
CMKFQVZJOWHHDV-NQZBTDCJSA-N
FDA UNII
WT0YJV846J

Catharanthine
catharanthine is a natural product found in Catharanthus trichophyllus, Tabernaemontana catharinensis, and other organisms with data available.
1 2D Structure

Catharanthine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
methyl (1R,15R,18R)-17-ethyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8,16-pentaene-1-carboxylate
2.1.2 InChI
InChI=1S/C21H24N2O2/c1-3-14-10-13-11-21(20(24)25-2)18-16(8-9-23(12-13)19(14)21)15-6-4-5-7-17(15)22-18/h4-7,10,13,19,22H,3,8-9,11-12H2,1-2H3/t13-,19+,21-/m0/s1
2.1.3 InChI Key
CMKFQVZJOWHHDV-NQZBTDCJSA-N
2.1.4 Canonical SMILES
CCC1=CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC
2.1.5 Isomeric SMILES
CCC1=C[C@H]2C[C@]3([C@@H]1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC
2.2 Other Identifiers
2.2.1 UNII
WT0YJV846J
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Catharanthine Monohydrochloride, (2alpha,5beta,6alpha,18beta)-isomer

2. Catharanthine Sulfate, (2alpha,5beta,6alpha,18beta)-isomer

2.3.2 Depositor-Supplied Synonyms

1. 2468-21-5

2. Catharanthin

3. Catharanthine Base

4. (+)-catharanthine

5. (+)-3,4-didehydrocoronaridine

6. Wt0yjv846j

7. Chembl2163793

8. Ibogamine-18-carboxylic Acid, 3,4-didehydro-, Methyl Ester, (2alpha,5beta,6alpha,18beta)-

9. Catharanthine, (+)-

10. Unii-wt0yjv846j

11. Einecs 219-586-6

12. Catharanthine [mi]

13. Chebi:3469

14. Dtxsid80947621

15. (+)-3, 4-didehydrocoronaridine

16. Catharanthine, >=95% (hplc)

17. Hms2095f15

18. Hms3652a13

19. Hms3712f15

20. Hms3885k13

21. Bdbm50396009

22. Mfcd01753356

23. S3202

24. Zinc57297068

25. Akos024463388

26. Methyl (2alpha,5beta,6alpha)-3,4-didehydroibogamine-18beta-carboxylate

27. Ccg-220187

28. Methyl (2-alpha,5-beta,6-alpha,18-beta)-3,4-didehydroibogamine-18-carboxylate

29. Ac-34053

30. Sw198653-2

31. Ab01566866_01

32. 468c215

33. Q-100319

34. Methyl (2alpha,18beta)-3,4-didehydroibogamine-18-carboxylate

35. (1beta,4beta)-2,6-[ethylene(1h-indole-3,2-diyl)]-7-ethyl-2-azabicyclo[2.2.2]octa-7-ene-6beta-carboxylic Acid Methyl Ester

36. (6r,6ar,9r,11r)-methyl 7-ethyl-6,6a,9,10,12,13-hexahydro-5h-6,9-methanopyrido[1',2':1,2]azepino[4,5-b]indole-6-carboxylate

37. (6r,6ar,9r,11r)-methyl7-ethyl-6,6a,9,10,12,13-hexahydro-5h-6,9-methanopyrido[1',2':1,2]azepino[4,5-b]indole-6-carboxylate

38. Ibogamine-18-carboxylic Acid, 3,4-didehydro-, Methyl Ester, (2-alpha,5-beta,6-alpha,18-beta)-

39. Ibogamine-18-carboxylic Acid, 3,4-didehydro-, Methyl Ester,(2.alpha.,5.beta.,6.alpha.,18.beta.)-

40. Methyl (1r,15r,18r)-17-ethyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8,16-pentaene-1-carboxylate

2.4 Create Date
2006-02-27
3 Chemical and Physical Properties
Molecular Weight 336.4 g/mol
Molecular Formula C21H24N2O2
XLogP32.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass336.183778013 g/mol
Monoisotopic Mass336.183778013 g/mol
Topological Polar Surface Area45.3 Ų
Heavy Atom Count25
Formal Charge0
Complexity603
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 2468-21-5 / Catharanthine API manufacturers, exporters & distributors?

Catharanthine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Catharanthine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Catharanthine manufacturer or Catharanthine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Catharanthine manufacturer or Catharanthine supplier.

PharmaCompass also assists you with knowing the Catharanthine API Price utilized in the formulation of products. Catharanthine API Price is not always fixed or binding as the Catharanthine Price is obtained through a variety of data sources. The Catharanthine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Catharanthine

Synonyms

2468-21-5, Catharanthin, Catharanthine base, (+)-catharanthine, (+)-3,4-didehydrocoronaridine, Wt0yjv846j

Cas Number

2468-21-5

Unique Ingredient Identifier (UNII)

WT0YJV846J

About Catharanthine

catharanthine is a natural product found in Catharanthus trichophyllus, Tabernaemontana catharinensis, and other organisms with data available.

Catharanthine Manufacturers

A Catharanthine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Catharanthine, including repackagers and relabelers. The FDA regulates Catharanthine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Catharanthine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Catharanthine Suppliers

A Catharanthine supplier is an individual or a company that provides Catharanthine active pharmaceutical ingredient (API) or Catharanthine finished formulations upon request. The Catharanthine suppliers may include Catharanthine API manufacturers, exporters, distributors and traders.

Catharanthine GMP

Catharanthine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Catharanthine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Catharanthine GMP manufacturer or Catharanthine GMP API supplier for your needs.

Catharanthine CoA

A Catharanthine CoA (Certificate of Analysis) is a formal document that attests to Catharanthine's compliance with Catharanthine specifications and serves as a tool for batch-level quality control.

Catharanthine CoA mostly includes findings from lab analyses of a specific batch. For each Catharanthine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Catharanthine may be tested according to a variety of international standards, such as European Pharmacopoeia (Catharanthine EP), Catharanthine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Catharanthine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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