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Chemistry

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Also known as: 1100318-47-5, Ccx140, Ilacirnon, Ccx140-b, Ilacirnon [usan], Ccx-140
Molecular Formula
C20H13ClF3N5O3S
Molecular Weight
495.9  g/mol
InChI Key
LUUMLYXKTPBTQR-UHFFFAOYSA-N
FDA UNII
380F68J5PH

CCX140
CCX-140 is under investigation in clinical trial NCT01440257 (A Study to Evaluate the Effect of CCX140-B on Urinary Albumin Excretion in Subjects With Type 2 Diabetes and Albuminuria).
1 2D Structure

CCX140

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-chloro-N-[5-methyl-2-(7H-pyrrolo[2,3-d]pyrimidine-4-carbonyl)pyridin-3-yl]-3-(trifluoromethyl)benzenesulfonamide
2.1.2 InChI
InChI=1S/C20H13ClF3N5O3S/c1-10-6-15(29-33(31,32)11-2-3-14(21)13(7-11)20(22,23)24)17(26-8-10)18(30)16-12-4-5-25-19(12)28-9-27-16/h2-9,29H,1H3,(H,25,27,28)
2.1.3 InChI Key
LUUMLYXKTPBTQR-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=CC(=C(N=C1)C(=O)C2=C3C=CNC3=NC=N2)NS(=O)(=O)C4=CC(=C(C=C4)Cl)C(F)(F)F
2.2 Other Identifiers
2.2.1 UNII
380F68J5PH
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Ccx140-b

2.3.2 Depositor-Supplied Synonyms

1. 1100318-47-5

2. Ccx140

3. Ilacirnon

4. Ccx140-b

5. Ilacirnon [usan]

6. Ccx-140

7. Chembl2178573

8. 380f68j5ph

9. Mfcd30378911

10. 4-chloro-n-[5-methyl-2-(7h-pyrrolo[2,3-d]pyrimidine-4-carbonyl)pyridin-3-yl]-3-(trifluoromethyl)benzenesulfonamide

11. 4-chloro-n-(5-methyl-2-(7h-pyrrolo(2,3-d)pyrimidin-4-ylcarbonyl)-3-pyridinyl)-3-(trifluoromethyl)benzenesulfonamide

12. 4-chloro-n-(5-methyl-2-(7h-pyrrolo[2,3-d]pyrimidine-4-carbonyl)pyridin-3-yl)-3-(trifluoromethyl)benzenesulfonamide

13. Ilacirnon [inn]

14. Ccx140b

15. Schembl127113

16. Unii-380f68j5ph

17. Ccx-140b

18. Ccx140-bccx140-b

19. Gtpl11185

20. Ccx140b; Ccx140 B

21. Bcp25695

22. Ex-a2956

23. Ac1940

24. Bdbm50398343

25. Who 11339

26. Zinc43204193

27. Cs-6448

28. Example 5 [wo2009009740a1]

29. Ac-31374

30. Cs-12273

31. Sy044972

32. Db-106774

33. Hy-101713

34. 4-chloro-n-(5-methyl-2-(7h-pyrrolo[2,3-d]pyrimidine-4-carbonyl)pyridin-3-yl)-3-(trifluoromethyl)benzenesulfonamidedine-4-carbonyl)pyridin-3-yl)-3-(trifluoromethyl)benzenesulfonamide

35. 4-chloro-n-[5-methyl-2-(7h-pyrrolo[2,3-d]pyrimidine-4-carbonyl)-pyridin-3-yl]-3-trifluoromethyl-benzenesulfonamide

36. Benzenesulfonamide, 4-chloro-n-(5-methyl-2-(7h-pyrrolo(2,3-d)pyrimidin-4-ylcarbonyl)-3-pyridinyl)-3-(trifluoromethyl)-

2.4 Create Date
2009-01-26
3 Chemical and Physical Properties
Molecular Weight 495.9 g/mol
Molecular Formula C20H13ClF3N5O3S
XLogP34.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count10
Rotatable Bond Count5
Exact Mass495.0379726 g/mol
Monoisotopic Mass495.0379726 g/mol
Topological Polar Surface Area126 Ų
Heavy Atom Count33
Formal Charge0
Complexity827
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 1100318-47-5 / CCX140 API manufacturers, exporters & distributors?

CCX140 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of CCX140 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right CCX140 manufacturer or CCX140 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred CCX140 manufacturer or CCX140 supplier.

PharmaCompass also assists you with knowing the CCX140 API Price utilized in the formulation of products. CCX140 API Price is not always fixed or binding as the CCX140 Price is obtained through a variety of data sources. The CCX140 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

CCX140

Synonyms

1100318-47-5, Ilacirnon, Ccx140-b, Ilacirnon [usan], Ccx-140, Chembl2178573

Cas Number

1100318-47-5

Unique Ingredient Identifier (UNII)

380F68J5PH

About CCX140

CCX-140 is under investigation in clinical trial NCT01440257 (A Study to Evaluate the Effect of CCX140-B on Urinary Albumin Excretion in Subjects With Type 2 Diabetes and Albuminuria).

CCX140 Manufacturers

A CCX140 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of CCX140, including repackagers and relabelers. The FDA regulates CCX140 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. CCX140 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

CCX140 Suppliers

A CCX140 supplier is an individual or a company that provides CCX140 active pharmaceutical ingredient (API) or CCX140 finished formulations upon request. The CCX140 suppliers may include CCX140 API manufacturers, exporters, distributors and traders.

CCX140 GMP

CCX140 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of CCX140 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right CCX140 GMP manufacturer or CCX140 GMP API supplier for your needs.

CCX140 CoA

A CCX140 CoA (Certificate of Analysis) is a formal document that attests to CCX140's compliance with CCX140 specifications and serves as a tool for batch-level quality control.

CCX140 CoA mostly includes findings from lab analyses of a specific batch. For each CCX140 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

CCX140 may be tested according to a variety of international standards, such as European Pharmacopoeia (CCX140 EP), CCX140 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (CCX140 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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